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Prof. Dr. Dr. Zeno Földes-Papp [Biochemist, Gerontologist]: Single-Molecule Biophysics & Biochemistry Based On the Stochastic Nature of Diffusion

Prof. Dr.med. Dr.rer.nat. 
[Visiting Prof. (Univ. Kairo) Dr.med. Dr.rer.nat.]
Zeno Földes-Papp
ASKLEPIOS Klinik Lindau GmbH
Sektion Geriatrie
Friedrichshafener Strasse 82
D-88131 Lindau (am Bodensee)
Bayern
Deutschland


zeno.foldespapp@gmail.com
Prof. Dr.med. Dr.rer.nat. Zeno Földes-Papp [Visiting Professor (Univ. Kairo) Dr. med. Dr. rer. nat.] (Fuehrungsfaehigkeit des Professorentitels: Gutachten der Zentralstelle fuer auslaendisches Bildungswesen, Bonn, vom 07.07.2015 und Leiter des Sachgebiets Meldewesen der Aerztekammer Niedersachsen, Hannover, vom 06.11.2019 und des Aerztlichen Bezirksverbandes Schwaben, Augsburg, Bayern (Koerperschaft des oeffentlichen Rechts, zustaendiges Meldeswesen der Bayerischen Landesaerztekammer, Muenchen) vom 20.04.2020 sowie des Abteilungsleiters Zentrale Mitgliederverwaltung der Bayerischen Landesaerztekammer, Muenchen, mit Schreiben vom 23.04.2020).

The Bavarian Dementia Week 2023 is under the patronage of the Bavarian State Ministry for Health and Care:
https://www.demenzwoche.bayern.de/
AND
https://www.youtube.com/watch?v=hZR3hBO1mu4
https://www.youtube.com/results?search_query=Foeldes-Papp
https://www.youtube.com/results?search_query=Foeldes-Papp+Depression
AND
https://www.landkreis-lindau.de/?ffmod=suche&opt3=&NavID=2562.5&such=Bayerische+Demenzwoche+2023
ALSO
https://www.youtube.com/watch?v=YKloBUPilD8&t=1s


From the Mathematical Core To the Physical Theory - The thermodynamic Single-Molecule Demon!


Digman M.A., Gratton E. Annu. Rev. Phys. Chem. 2011; 62: 645–668: „ … the concept of fluctuations due to the same molecule was only raised recently by the pioneering work of Földes-Papp and colleagues (80–84).“ That is the INDIVIDUAL MOLECULE in dilute liquids and live cells without immobilization or hydrodynamic flow.
[80]. Földes-Papp Z. Fluorescence fluctuation spectroscopic approaches to the study of a single molecule diffusing in solution and a live cell without systemic drift or convection: a theoretical study. Curr. Pharm. Biotechnol. 2007; 8:261–73. [PubMed: 17979724]
[81]. Földes-Papp Z. ‘True’ single-molecule molecule observations by fluorescence correlation spectroscopy and two-color fluorescence cross-correlation spectroscopy. Exp. Mol. Pathol. 2007; 82:147–55. [PubMed: 17258199]
[82]. Földes-Papp Z. What it means to measure a single molecule in a solution by fluorescence fluctuation spectroscopy. Exp. Mol. Pathol. 2006; 80:209–18. [PubMed: 16515783]
Richard Levenson, Professor and Vice Chair for Strategic Technologies, Dept. at UC Davis, Davis, California, USA, wrote to me on May 24, 2021: "Much easier on Pluto, I imagine. A very cold, former planet. Not too much thermodynamic jitter at -233 C." Although the experimental attempt to measure a single molecule/particle (i.e. an individual molecule/particle) at room temperature in dilute liquids and live cells without immobilization or hydrodynamic flow has failed - what kind of a failure is this? – this failure, which spurred the theory on Brownian molecular motion in order to measure an individual molecule/particle, surpasses the greatest successes of most others.:
https://benthamsciencepublishers.wordpress.com/2022/06/30/study-on-single-molecule-biophysics-and-biochemistry-in-liquids-and-livecellsno-immobilization-flow/
Instead of citing trendy and mediocre articles on studies "at the single-molecule level” in dilute liquids and live cells or on single molecules in diffusion processes, you may read insightful research articles on the quantiffication of thermodynamic jitter in the time domain (for example, the Brownian motion of molecules and particles) below:
These dubious and far-fetched, i.e. non-serious and therefore pseudo-scientific, publications "at the single-molecule level” in dilute liquids and live cells without immobilization or significant hydrodynamic flow or on single molecules in diffusion processes will be replaced with that bright future. I think we can leave it at that.
A head start is a proven theory, e.g. proven mathematically, that turns knowledge into strength, even at odds with the mediocre mainstream. What new insights can be gained from the foundation of Single-Molecule Biophysics & Biochemistry Based On the Stochastic Nature of Diffusion? The thermodynamic signatures of single molecules and single particles in liquids and live cells (cytoplasm, membranes) without immobilization or without hydrodynamic flow
https://ajtm.journals.publicknowledgeproject.org/index.php/ajtm/article/view/2841/2537
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