Abstract: The n-3 fatty acids are unanimously considered as high nutritional value molecules,
especially Long-Chains PUFA from marine origin. However, most of the products available in the market
contain LC-PUFA esterified on the glycerol under the common form of triacylglycerols. Another interesting
way can be to esterify the PUFA on polar lipids and especially on Phospholipids. An original patented
enzymatic process carried out under mild conditions (low temperature, no use of organic solvent) is
presented to produce at industrial scale a Phospho-Lipo-Peptidic Complex, that is particularly rich in DHA
esterified on the sn-2 position on PL.