http://publicationslist.org/data/Ian.Adams/atom.xml Ian Adamshttp://publicationslist.org/Ian.Adams$basepathfavicon.icoRecent additions to Ian Adams's PublicationsList.org pagehttp://publicationslist.org/publications.png2011-12-10T01:23:25Z http://publicationslist.org/Ian.Adams/refid1 2011-12-10T01:20:46Z

In recent years, declines in honey bee (Apis mellifera L.) colonies have been observed to varying degrees worldwide with the worst losses in the USA being termed Colony Collapse Disorder (CCD). Pathogen load and the prevalence of honey bee viruses have been implicated in these losses and many diseased hives have multiple viruses present. We have designed and tested an oligonucleotide microarray wh...<br/><br/>Rachel H Glover, Ian P Adams, Giles Budge, Selwyn Wilkins, Neil Boonham (2011) <i>J Invertebr Pathol</i> <i></i> <i></i> 107: 3 216-219<br/>

http://publicationslist.org/Ian.Adams/refid3 2011-12-10T01:22:58Z

The complete genome sequence for an isolate of the Ugandan and Tanzanian strain types of Cassava brown streak virus have been determined using the novel approach of non-directed next generation sequencing. Comparison of the genome sequences revealed that CBSV is highly heterogeneous at the isolate level as well as the strain level. The isolate of the Ugandan strain was found to have a genome 9,070...<br/><br/>Wendy A Monger, T Alicai, J Ndunguru, Z M Kinyua, M Potts, R H Reeder, D W Miano, I P Adams, N Boonham, R H Glover, J Smith (2010) <i>Arch Virol</i> <i></i> <i></i> 155: 3 429-433<br/>

http://publicationslist.org/Ian.Adams/refid2 2011-12-10T01:22:58Z

Canna yellow streak virus (Potyvirus, Potyviridae) was sequenced using the novel method of next-generation pyrosequencing. The complete genome was found to be 9,502 nucleotides excluding the poly-A tail with a predicted genome organisation typical for a member of the genus Potyvirus. As with other potyviruses that infect monocotyledons, some of the predicted cleavage sites of the polyprotein genom...<br/><br/>W A Monger, I P Adams, R H Glover, B Barrett (2010) <i>Arch Virol</i> <i></i> <i></i> 155: 9 1515-1518<br/>

http://publicationslist.org/Ian.Adams/refid4 2011-12-10T01:22:58Z

A novel, unbiased approach to plant viral disease diagnosis has been developed which requires no a priori knowledge of the host or pathogen. Next-generation sequencing coupled with metagenomic analysis was used to produce large quantities of cDNA sequence in a model system of tomato infected with Pepino mosaic virus. The method was then applied to a sample of Gomphrena globosa infected with an unk...<br/><br/>Ian P Adams, Rachel H Glover, Wendy A Monger, Rick Mumford, Elena Jackeviciene, Meletele Navalinskiene, Marija Samuitiene, Neil Boonham (2009) <i>Mol Plant Pathol</i> <i></i> <i></i> 10: 4 537-545<br/>

http://publicationslist.org/Ian.Adams/refid5 2011-12-10T01:20:46Z

Malic enzyme (ME; NADP(+)-dependent; EC 1 . 1 . 1 . 40) has been postulated to be the rate-limiting step for fatty acid biosynthesis in oleaginous fungi in which the extent of lipid accumulation is below the maximum possible. The genes encoding the isoform of ME involved in fatty acid synthesis were identified in Mucor circinelloides and Mortierella alpina, two commercially useful oil-producing fu...<br/><br/>Ying Zhang, Ian P Adams, Colin Ratledge (2007) <i>Microbiology</i> <i></i> <i></i> 153: Pt 7 2013-2025<br/>

http://publicationslist.org/Ian.Adams/refid6 2011-12-10T01:20:46Z

A 3193 bp contiguous sequence has been cloned from the oleaginous fungus Mucor circinelloides, that contains a full-length gene encoding a putative NADP+: dependent malic enzyme (EC. 1.1.1.40). The cloned DNA contains a 2154 bp putative open reading frame containing five introns and encoding a protein of 616 amino acids. The gene encoded what appeared to be an anaerobic isoform of malic enzyme (is...<br/><br/>Yonghua Li, Ian P Adams, James P Wynn, Colin Ratledge (2005) <i>Mycol Res</i> <i></i> <i></i> 109: Pt 4 461-468<br/>

http://publicationslist.org/Ian.Adams/refid7 2011-12-10T01:20:46Z

Angiogenesis is characterised by activation, migration and proliferation of endothelial cells and is central to the pathology of cancer, cardiovascular disease and chronic inflammation. Somatostatin is an inhibitory polypeptide that acts through five receptors (sst 1, 2, 3, 4, 5). Sst has previously been reported in endothelium, but their role remains obscure. Here, we report the expression of sst...<br/><br/>R L Adams, I P Adams, S W Lindow, W Zhong, S L Atkin (2005) <i>Br J Cancer</i> <i></i> <i></i> 92: 8 1493-1498<br/>

http://publicationslist.org/Ian.Adams/refid8 2011-12-10T01:20:46Z

Somatostatin (SST) modulates exocrine and endocrine secretion, proliferation and apoptosis via five G protein-linked receptors (SSTRs 1-5). Long-acting SST analogues such as Octreotide, and the new analogue SOM230, have been developed for the treatment of neuroendocrine tumours. Octreotide has previously been reported to inhibit endothelial proliferation. We wished to determine if SOM230 is a more...<br/><br/>Robyn L Adams, Ian P Adams, Stephen W Lindow, Stephen L Atkin (2004) <i>Clin Endocrinol (Oxf)</i> <i></i> <i></i> 61: 4 431-436<br/>

http://publicationslist.org/Ian.Adams/refid10 2011-12-10T01:20:46Z

ATP:citrate lyase (ACL), an important enzyme in lipid synthesis, has been purified from Aspergillus nidulans to a specific activity of 19.6 micromol min(-1) mg(-1), almost twice that of any other purified ACL and shown to be distinct from any previously purified ACL. The enzyme is a 371+/-31 kDa hexamer of 3 alpha, 3 beta proteins, unlike the 4 alpha tetramer found in rats or yeasts. The molecular...<br/><br/>Ian P Adams, Stephen Dack, F Mark Dickinson, Colin Ratledge (2002) <i>Biochim Biophys Acta</i> <i></i> <i></i> 1597: 1 36-41<br/>

http://publicationslist.org/Ian.Adams/refid9 2011-12-10T01:20:46Z

Somatostatin mediates its many inhibitory functions through five G-protein-coupled receptors (sstr1-5); however, it is not known whether somatostatin or its receptors are present in the endometrium.<br/><br/>Victoria L Green, I Richmond, S Maguiness, J Robinson, L Helboe, I P Adams, N S Drummond, S L Atkin (2002) <i>Clin Endocrinol (Oxf)</i> <i></i> <i></i> 56: 5 609-614<br/>

http://publicationslist.org/Ian.Adams/refid11 2011-12-10T01:22:07Z

Statins block de novo synthesis of cholesterol by inhibiting the enzyme, HMG CoA reductase. The product of this reaction, mevalonic acid, is also a precursor of isoprenoids, molecules required for the activation of signalling G-proteins, such as Ras. Signal transduction pathways involving Ras are important for cell survival and this may be why statins induce apoptotic death of several cell types. ...<br/><br/>C J Newton, G Ran, Y-X Xie, D Bilko, C H Burgoyne, I Adams, A Abidia, P T McCollum, S L Atkin (2002) <i>J Endocrinol</i> <i></i> <i></i> 174: 1 7-16<br/>