http://publicationslist.org/data/S.C.Mizrak/atom.xmlSefika Mizrak's Publications ListSefika Mizrakhttp://publicationslist.org/S.C.Mizrak$basepathfavicon.icoRecent additions to Sefika Mizrak's PublicationsList.org pagehttp://publicationslist.org/publications.png2008-08-22T07:54:23Zhttp://publicationslist.org/S.C.Mizrak/refid52008-08-22T07:53:00ZPropagation of Bovine Spermatogonial Stem Cells In VitroThe access to sufficient numbers of spermatogonial stem cells (SSC) is a prerequisite for the study of their regulation and further biomanipulation. A specialized medium and several growth factors were tested to study the in vitro behaviour of bovine type A spermatogonia, a cell population that includes the SSC and can be specifically stained for the lectin DBA (Dolichos bifflorus agglutinin). Dur...<br/><br/>P. Aponte, T. Soda, K. Teerds, S.C. Mizrak, H. van de Kant, D.G. de Rooij (2008) <i>Reproduction</i> 28: <br/>http://publicationslist.org/S.C.Mizrak/refid12008-08-22T07:20:56ZDeriving multipotent stem cells from mouse spermatogonial stem cells: a new tool for developmental and clinical researchIn recent years, embryonic stem (ES) cell-like cells have been obtained from cultured mouse spermatogonial stem cells (SSCs). These advances have shown that SSCs can transition from being the stem cell-producing cells of spermatogenesis to being multipotent cells that can differentiate into derivatives of all three germ layers. As such, they offer new possibilities for studying the mechanisms that...<br/><br/>D.G. de Rooij, S.C. Mizrak (2008) <i>Development</i> 13: 135 2207-13<br/>http://publicationslist.org/S.C.Mizrak/refid22008-08-22T07:23:40ZTransient receptor potential vanilloid receptor-1 confers heat resistance to male germ cellsTesticular hyperthermia in mice lacking transient receptor potential vanilloid receptor-1 results in a much more rapid and massive germ cell depletion from the seminiferous tubules than in wild-type animals, indicating that this receptor protects germ cells against heat stress.
<br/><br/>S.C. Mizrak, F.M. van Dissel-Emiliani (2008) <i>Fertility Sterility</i> 25: <br/>http://publicationslist.org/S.C.Mizrak/refid32008-08-22T07:45:53ZPhosphoprotein enriched in astrocytes-15 is expressed in mouse testis and protects spermatocytes from apoptosisPhosphoprotein enriched in astrocytes (PEA-15) is a 15 kDa acidic serine-phosphorylated protein expressed in different cell types, especially in the CN. We initially detected the expression of PEA-15 in primary cultures of Sertoli cells. To assess the presence and localization of PEA-15 in the mouse testis, we studied the expression pattern of the PEA-15 protein by immunohistochemistry and mRNA by...<br/><br/>S.C. Mizrak, F. Renault-Mihara, M. Párraga, J. Bogerd, H.J. van de Kant, P.P. López-Casas, M. Paz, J. del Mazo, D.G. de Rooij
(2007) <i>Reproduction</i> 4: 133 743-51<br/>http://publicationslist.org/S.C.Mizrak/refid42008-08-22T07:48:36ZExpression of stress inducible protein 1 (Stip1) in the mouse testisPhthalate esters are considered endocrine disruptors that interfere with the endocrine balance and development of the mammalian testis. Mono-2-ethylhexyl phthalate (MEHP), the active metabolite of the ubiquitously used plasticizer di-2-ethylhexyl phthalate (DEHP), acts upon Sertoli cells as initial target. By subtractive cDNA libraries we identified genes deregulated as response to MEHP in primary...<br/><br/>S.C. Mizrak, J. Bogerd, P.P. Lopez-Casas, M. Párraga, J. Del Mazo, D. G. de Rooij (2006) <i>Molecular Reproduction and Development</i> 11: 73 1361-6<br/>