http://publicationslist.org/data/Ulf.Lindh/atom.xml Ulf Lindhhttp://publicationslist.org/Ulf.Lindh$basepathfavicon.icoRecent additions to Ulf Lindh's PublicationsList.org pagehttp://publicationslist.org/publications.png2008-06-15T16:39:51Z http://publicationslist.org/Ulf.Lindh/refid2 2008-06-15T16:36:46Z

Ulf Lindh (2007) <i>Ambio</i> <i></i> <i></i> 36: 1 107-110<br/>

http://publicationslist.org/Ulf.Lindh/refid1 2008-06-15T16:36:46Z

This study aimed to investigate a possible connection between removal of dental amalgam restorations supported by antioxidant therapy and indicative changes of clinical chemistry parameters. A group of 24 patients, referred for complaints related to amalgam restorations, underwent a removal of their amalgams. All patients were treated with antioxidants (vitamin B-complex, vitamin C, vitamin E, and...<br/><br/>Peter Frisk, Antero Danersund, Romuald Hudecek, Ulf Lindh (2007) <i>Biol Trace Elem Res</i> <i></i> <i></i> 120: 1-3 163-170<br/>

http://publicationslist.org/Ulf.Lindh/refid6 2008-06-15T16:36:46Z

Cadmium (Cd) is a potentially toxic metal widely distributed in the environment and known to cause adverse health effects in humans. During coxsackievirus infection, the concentrations of essential and nonessential trace elements (e.g., iron (Fe), copper (Cu), and Cd) change in different target organs of the infection. Fe and Cu are recognized cofactors in host defence reactions, and Fe is known t...<br/><br/>N-G Ilbäck, U Lindh, R Minqin, G Friman, F Watt (2006) <i>Environ Res</i> <i></i> <i></i> 102: 3 308-313<br/>

http://publicationslist.org/Ulf.Lindh/refid5 2008-06-15T16:36:46Z

OBJECTIVES: This study was done to evaluate the results and clinical relevance of an optimized lymphocyte proliferation test, MELISA, for metal-induced inflammation in patients with CFS-like symptoms. The treatment of patients consisted of the replacement of incompatible dental materials (RID) together with supportive anti-oxidant therapy. DESIGN OF THE STUDY: 513 patients were tested by MELISA at...<br/><br/>Amer Yaqob, Antero Danersund, Vera Dm Stejskal, Anders Lindvall, Romuald Hudecek, Ulf Lindh (2006) <i>Neuro Endocrinol Lett</i> <i></i> <i></i> 27: 1-2 189-197<br/>

http://publicationslist.org/Ulf.Lindh/refid8 2008-06-15T16:36:46Z

Amalgam separators are used to physically remove dental amalgam from waste water in dental clinics. They are thereby supposed to reduce mercury (Hg) emissions to the municipal waste water system to acceptable levels. We here present results from a comparative study in situ of three amalgam separators available on the market, all with a claimed efficiency of 99% according to Danish and ISO protocol...<br/><br/>Lars D Hylander, Anders Lindvall, Roland Uhrberg, Lars Gahnberg, Ulf Lindh (2006) <i>Sci Total Environ</i> <i></i> <i></i> 366: 1 320-336<br/>

http://publicationslist.org/Ulf.Lindh/refid4 2008-06-15T16:36:46Z

Arsenic (As), a potentially toxic trace element, has been shown to influence viral replication and resistance to microbial infection. However, the impact of infection on the normal As status in target organs involved in the disease process has not been studied to date. In the present study, As was measured through inductively coupled plasma mass spectrometry in the plasma, liver, spleen, kidney, h...<br/><br/>Gad Benyamin, Ulf Lindh, Peter Frisk, Göran Friman, Nils-Gunnar Ilbäck (2006) <i>J Trace Elem Med Biol</i> <i></i> <i></i> 20: 2 121-126<br/>

http://publicationslist.org/Ulf.Lindh/refid3 2008-06-15T16:36:46Z

The objective of this study was to determine the concentration changes of 13 elements in erythrocytes and plasma after the removal of dental amalgam and other metal alloys. Blood samples from 250 patients were collected, separated into erythrocytes and plasma, and analyzed by inductively coupled plasma-mass spectrometry. The 250 patients were divided into 3 groups (Negative, Zero, and Positive) de...<br/><br/>Peter Frisk, Anders Lindvall, Romuald Hudecek, Ulf Lindh (2006) <i>Biol Trace Elem Res</i> <i></i> <i></i> 113: 3 247-259<br/>

http://publicationslist.org/Ulf.Lindh/refid7 2008-06-15T16:36:46Z

As part of the general host response to coxsackievirus B3 (CB3) infection, the concentration of essential and nonessential trace elements changes in different target organs of the infection. Essential (e.g., Se) and nonessential (e.g., Hg) trace elements are known to interact and affect inflammatory tissue lesions induced by CB3 infection. However, it is unknown whether these changes involve the b...<br/><br/>Nils-Gunnar Ilbäck, Ulf Lindh, Ren Minqin, Göran Friman, Frank Watt (2005) <i>Biol Trace Elem Res</i> <i></i> <i></i> 108: 1-3 215-224<br/>

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In experimental studies on the common human coxsackievirus B type 3 (CB3) infection, administered cadmium (Cd) is known to accumulate in the liver and kidneys. CB3 adapted to Balb/c mice was used to study whether infection affects the Cd-binding protein, metallothionein (MT) and if this alters the normal physiological trace element balance in the liver, kidney, spleen and brain. On day 3 of infect...<br/><br/>Nils-Gunnar Ilbäck, Anders W Glynn, Lotta Wikberg, Elvy Netzel, Ulf Lindh (2004) <i>Toxicology</i> <i></i> <i></i> 199: 2-3 241-250<br/>

http://publicationslist.org/Ulf.Lindh/refid10 2008-06-15T16:36:46Z

The pathogenesis of some heart diseases has been associated with changes in the balance of certain trace elements. However, whether blood trace element changes exist that are related to changes in the cardiovascular system are, in most cases, unknown. In this study, blood trace element levels were analysed in 46 patients with non-rheumatic aortic valve sclerosis that were previously shown to have ...<br/><br/>Christina Nyström-Rosander, Ulf Lindh, Göran Friman, Olle Lindqvist, Stefan Thelin, Nils-Gunnar Ilbäck (2004) <i>Biometals</i> <i></i> <i></i> 17: 2 121-128<br/>

http://publicationslist.org/Ulf.Lindh/refid15 2008-06-15T16:37:09Z

The objective was to study toxin-induced effects on physiological parameters in the rabbit and whether these parameters show dose-response and co-variation after administration of a recombinant fusion protein between staphylococcal enterotoxin (SE) and the Fab fragment of an antibody. Rabbits are very sensitive to SE toxins and the cardiovascular and immune effects are similar to those observed in...<br/><br/>Nils Gunnar Ilbäck, Kjell Gunnarsson, Robert Persson, Ulf Lindh, Torbjörn Stålhandske (2003) <i>Toxicology</i> <i></i> <i></i> 185: 1-2 161-174<br/>

http://publicationslist.org/Ulf.Lindh/refid14 2008-06-15T16:37:09Z

INTRODUCTION: The trigger for some cases of juvenile diabetes has been suggested to be an interaction between a virus and various trace elements. Infection with human coxsackievirus B3 (CB3) in the murine model results in viral replication and inflammation in the pancreas. AIM: To determine how infection affects the trace element balance in the pancreas. METHODOLOGY: Concentrations of the followin...<br/><br/>Nils-Gunnar Ilbäck, Gad Benyamin, Ulf Lindh, Jan Fohlman, Göran Friman (2003) <i>Pancreas</i> <i></i> <i></i> 26: 2 190-196<br/>

http://publicationslist.org/Ulf.Lindh/refid13 2008-06-15T16:37:09Z

An association between Chlamydia pneumoniae and atherosclerotic cardiovascular diseases has been suggested. However, other factors may interact in the pathogenesis of valve sclerosis. Therefore, trace elements important for C. pneumoniae growth and host defense and markers of C. pneumoniae infection were studied in sclerotic valves and serum. Forty-six patients undergoing surgical valve replacemen...<br/><br/>Christina Nyström-Rosander, Ulf Lindh, Nils-Gunnar Ilbäck, Eva Hjelm, Stefan Thelin, Olle Lindqvist, Göran Friman (2003) <i>Biol Trace Elem Res</i> <i></i> <i></i> 91: 2 97-110<br/>

http://publicationslist.org/Ulf.Lindh/refid11 2008-06-15T16:37:09Z

Selenium and mercuric chloride (MC) interactions regarding effects on cell growth and cell death have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) and with MC (35 or 50 microM). The 35-microM MC treatments resulted in a clear inhibition of cell growth with no obvious difference between mercury-...<br/><br/>Peter Frisk, Kenneth Wester, Amer Yaqob, Ulf Lindh (2003) <i>Biol Trace Elem Res</i> <i></i> <i></i> 92: 2 105-114<br/>

http://publicationslist.org/Ulf.Lindh/refid12 2008-06-15T16:37:09Z

In Coxsackievirus B3 (CB3) infection, the heart and pancreas are major target organs and, as a general host response, an associated immune activation and acute phase reaction develops. Although iron (Fe), copper (Cu), and zinc (Zn) are involved in these responses, sequential trace element changes in different target organs of infection have not been studied to date. In the present study, Fe, Cu, a...<br/><br/>Nils-Gunnar Ilbäck, Gad Benyamin, Ulf Lindh, Göran Friman (2003) <i>Biol Trace Elem Res</i> <i></i> <i></i> 91: 2 111-124<br/>

http://publicationslist.org/Ulf.Lindh/refid19 2008-06-15T16:37:09Z

A myocarditic coxsackievirus B3 (CB3) infection in adult male A/J mice was used to investigate the effects of 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD) exposure on mortality and on inflammatory lesion, virus and trace element contents of the heart. The mice were injected with four weekly intraperitoneal (i.p.) injections of TCDD (a loading dose of 5 microg/kg followed by three maintenance dose...<br/><br/>Eva Funseth, Lars Wesslén, Ulf Lindh, Göran Friman, Nils-Gunnar Ilbäck (2002) <i>Sci Total Environ</i> <i></i> <i></i> 284: 1-3 135-147<br/>

http://publicationslist.org/Ulf.Lindh/refid18 2008-06-15T16:37:09Z

Several trace elements are essential nutrients for an optimal functioning of organs and tissues, including the immune system and the heart. The pathogenesis of some heart diseases has been associated with changes in the balance of certain trace elements. The etiology of nonrheumatic aortic valve sclerosis is unknown, however. A prospective study was performed on trace element changes in the sclero...<br/><br/>Christina Nyström-Rosander, Ulf Lindh, Stefan Thelin, Olle Lindquist, Göran Friman, Nils-Gunnar Ilbäck (2002) <i>Biol Trace Elem Res</i> <i></i> <i></i> 88: 1 9-24<br/>

http://publicationslist.org/Ulf.Lindh/refid17 2008-06-15T16:37:09Z

The interaction between selenium and cadmium was studied in relation to cellular uptake and expressions of selenium-cadmium interaction. Human K-562 cells were pre-treated or simultaneously treated with (5 or 50 microM) selenite or (10 or 50 microM) selenomethionine and with (60 or 75 microM) cadmium nitrate. Cells pre or simultaneously treated with selenite revealed increased cadmium concentratio...<br/><br/>Peter Frisk, Amer Yaqob, Ulf Lindh (2002) <i>Sci Total Environ</i> <i></i> <i></i> 296: 1-3 189-197<br/>

http://publicationslist.org/Ulf.Lindh/refid16 2008-06-15T16:37:09Z

OBJECTIVES: The purpose of this study was to evaluate treatment of patients suffering from chronic ill health with a multitude of symptoms associated with metal exposure from dental amalgam and other metal alloys. SETTING AND DESIGN: We included 796 patients in a retrospective study using a questionnaire about symptom changes, changes in quality of life as a consequence of treatment and assessment...<br/><br/>Ulf Lindh, Romuald Hudecek, Antero Danersund, Sture Eriksson, Anders Lindvall (2002) <i>Neuro Endocrinol Lett</i> <i></i> <i></i> 23: 5-6 459-482<br/>

http://publicationslist.org/Ulf.Lindh/refid23 2008-06-15T16:37:23Z

Twenty-seven consecutive patients with health problems associated with dental amalgam were recruited. In spite of thorough medical examinations, there were no diagnoses available. The patient group was dominated by women. A healthy age- and sex-matched control group with dental amalgams without symptoms was also recruited. Metal level monitoring in plasma and nuclear microscopy of isolated individ...<br/><br/>U Lindh, B Carlmark, S O Grönquist, A Lindvall (2001) <i>Clin Chem Lab Med</i> <i></i> <i></i> 39: 2 134-142<br/>

http://publicationslist.org/Ulf.Lindh/refid21 2008-06-15T16:37:23Z

Selenium and methylmercuric chloride (MMC) interactions regarding cellular uptake and selenium protection on MMC toxicity have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) together with (3.5 or 5 microM) MMC. Cells simultaneously treated with selenite or selenomethionine and 3.5 microM MMC show...<br/><br/>P Frisk, A Yaqob, K Nilsson, U Lindh (2001) <i>Biol Trace Elem Res</i> <i></i> <i></i> 80: 3 251-268<br/>

http://publicationslist.org/Ulf.Lindh/refid26 2008-06-15T16:37:23Z

The diverse genetic backgrounds of lupus-prone murine models, which produce both quantitative and qualitative differences in disease expression, may be a valuable resource for studying the influence of environmental exposure on autoimmune disease in sensitive populations. We tested this premise by exposing autoimmune-prone BXSB and the nonautoimmune C57BL/6 mice to the heavy metal mercury. Althoug...<br/><br/>K M Pollard, D L Pearson, P Hultman, T N Deane, U Lindh, D H Kono (2001) <i>Environ Health Perspect</i> <i></i> <i></i> 109: 1 27-33<br/>

http://publicationslist.org/Ulf.Lindh/refid20 2008-06-15T16:37:09Z

Selenium and mercuric chloride (MC) interactions regarding cellular uptake and selenium protection on MC toxicity have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) together with MC (35 or 50 microM). Both treatments with selenite showed an increase of mercury uptake with increased selenium dose...<br/><br/>P Frisk, A Yaqob, K Nilsson, J Carlsson, U Lindh (2001) <i>Biol Trace Elem Res</i> <i></i> <i></i> 81: 3 229-244<br/>

http://publicationslist.org/Ulf.Lindh/refid29 2008-06-15T16:37:23Z

The present study was undertaken in order to study the effects of the broad-acting chelating agent CaNa2-EDTA on plasma trace elements and cardiovascular function in anesthetised New Zealand White rabbits. Trace elements are important for cardiovascular and immune functions and the rabbit is a well-accepted species in cardiovascular studies. The test compound CaNa2-EDTA was administered intravenou...<br/><br/>N G Ilbäck, T Stålhandske, U Lindh (2000) <i>Biol Trace Elem Res</i> <i></i> <i></i> 76: 2 133-148<br/>

http://publicationslist.org/Ulf.Lindh/refid30 2008-06-15T16:37:23Z

Effects of some metals on the growth of cultured human erythroleukemia K-562 cells were investigated when grown in two different types of media based upon RPMI-1640 or Ham's F-10. The study on proliferation, using RPMI-1640 supplemented with sodium selenite, selenomethionine, mercuric chloride, methylmercuric chloride and cadmium nitrate showed no inhibition of growth at concentrations of 2.5, 25,...<br/><br/>P Frisk, A Yaqob, K Nilsson, J Carlsson, U Lindh (2000) <i>Biometals</i> <i></i> <i></i> 13: 2 101-111<br/>

http://publicationslist.org/Ulf.Lindh/refid31 2008-06-15T16:37:43Z

The aluminium content in bone has been related in several ways: to the weight of wet bone, to the weight of dry bone, to the weight of bone-ash and to the calcium content of bone. We determined the accuracy and precision of measurement (using an inductively coupled mass-spectrometer) in 30 bone samples taken from one patient. The coefficient of variation of the aluminium/weight-quotient was 12.4 p...<br/><br/>H O Hellström, U Lindh, B Mjöberg (2000) <i>Ups J Med Sci</i> <i></i> <i></i> 105: 1 67-71<br/>

http://publicationslist.org/Ulf.Lindh/refid27 2008-06-15T16:37:23Z

The selenium uptake and retention have been studied in K-562 cells exposed to selenite or selenomethionine. In the uptake experiments the cells were exposed to two doses of selenite (5 or 50 microM) or selenomethionine (10 or 50 microM). In the retention study the cells were treated for 2 h with the above mentioned doses of the selenocompounds before being observed at different times. The selenium...<br/><br/>P Frisk, A Yaqob, K Nilsson, J Carlsson, U Lindh (2000) <i>Biometals</i> <i></i> <i></i> 13: 3 209-215<br/>

http://publicationslist.org/Ulf.Lindh/refid28 2008-06-15T16:37:23Z

During most infections plasma, concentrations of trace elements change, but it is unclear if this reflects changes in infected target tissues. In coxsackievirus B3 (CB3) infection, the myocardium is a target in both humans and mice. The concentrations of 12 trace elements were analyzed by inductively coupled plasma-mass spectrometry (ICP-MS) in the myocardium of sham-inoculated controls and infect...<br/><br/>E Funseth, U Lindh, L Wesslén, G Friman, N G Ilbäck (2000) <i>Biol Trace Elem Res</i> <i></i> <i></i> 76: 2 149-160<br/>

http://publicationslist.org/Ulf.Lindh/refid25 2008-06-15T16:37:23Z

During most infections the plasma levels of trace elements change, but it is not clear if this reflects changes in the infected tissues. Coxsackievirus B3 (CB3) infection may result in viral replication, subsequent inflammation and changed trace element levels in the myocardium. In the present study, the trace element levels in the plasma and heart of adult male A/J mice were determined during the...<br/><br/>E Funseth, U Lindh, G Friman, N G Ilbäck (2000) <i>Biometals</i> <i></i> <i></i> 13: 4 361-367<br/>

http://publicationslist.org/Ulf.Lindh/refid24 2008-06-15T16:37:23Z

Methyl mercury (MeHg) has been shown to change Coxsackie virus type B3 (CB3) myocarditis in a direction compatible with the development of chronic disease. Murine models of CB3 myocarditis closely mimic the pathogenesis in humans. There are also indications that metals, such as mercury, and trace elements may interact and adversely affect viral replication and development of inflammatory lesions. ...<br/><br/>N G Ilbäck, U Lindh, L Wesslén, J Fohlman, G Friman (2000) <i>Biol Trace Elem Res</i> <i></i> <i></i> 78: 1-3 131-147<br/>

http://publicationslist.org/Ulf.Lindh/refid22 2008-06-15T16:37:23Z

Many patients attribute their health problems to amalgam and other dental metals. In genetically susceptible indviduals, mercury and gold may function as haptens and elicit allergic and autoimmune reactions. The frequency of metal-induced lymphocyte responses was examined in 3,162 patients in three European laboratories using MELISA(R), an optimized lymphocyte proliferation test. The patients suff...<br/><br/> Stejskal, Danersund, Lindvall, Hudecek, Nordman, Yaqob, Mayer, Bieger, Lindh (1999) <i>Neuro Endocrinol Lett</i> <i></i> <i></i> 20: 5 289-298<br/>

http://publicationslist.org/Ulf.Lindh/refid32 2008-06-15T16:37:43Z

Dental amalgam restorations are a significant source of mercury exposure in the human population, but their potential to cause systemic health effects is highly disputed. We examined effects on the immune system by giving genetically mercury-susceptible Brown Norway (BN) rats and mercury-resistant Lewis (LE) rats silver amalgam restorations in 4 molars of the upper jaw, causing a body burden simil...<br/><br/>P Hultman, U Lindh, P Hörsted-Bindslev (1998) <i>J Dent Res</i> <i></i> <i></i> 77: 6 1415-1425<br/>

http://publicationslist.org/Ulf.Lindh/refid35 2008-06-15T16:37:43Z

In order to elucidate the question of free radical involvement in acute porphyric crisis, antioxidants were administered to two acute intermittent porphyria patients with long-standing recurrent attacks. Clinical condition and urinary excretion of porphyrins and porphyrin precursors were monitored before, during and after an eight week therapy with daily doses of vitamin E, beta-carotene, ascorbic...<br/><br/>S Thunell, D Andersson, P Harper, A Henrichson, Y Floderus, U Lindh (1997) <i>Eur J Clin Chem Clin Biochem</i> <i></i> <i></i> 35: 6 427-433<br/>

http://publicationslist.org/Ulf.Lindh/refid34 2008-06-15T16:37:43Z

Effects of Pb2+, Ni2+, Hg2+ and Se4+ on cultured human glioma U-343MG cells were investigated considering uptake, toxicity and, in combination with radiation, clonogenic cells survival. The cells were exposed to 0-100 microM of the metals for a week before the evaluation. The tests showed a tendency to toxicity with 10 microM nickel although not significant (P > 0.05). Selenium, lead and mercury e...<br/><br/>P Frisk, A Saetre, B Couce, B Stenerlöw, J Carlsson, U Lindh (1997) <i>Biometals</i> <i></i> <i></i> 10: 4 263-270<br/>

http://publicationslist.org/Ulf.Lindh/refid33 2008-06-15T16:37:43Z

The incidence of fragility fractures has increased epidemically. Especially patients with senile dementia (including Alzheimer's disease) have a greatly increased risk of fragility fractures. Aluminum inhibits bone mineralization; the greater the aluminium exposure, the higher the risk of an early fracture. Aluminium is neurotoxic and may, in addition to genetic factors, play a role in the develop...<br/><br/>B Mjöberg, E Hellquist, H Mallmin, U Lindh (1997) <i>Acta Orthop Scand</i> <i></i> <i></i> 68: 6 511-514<br/>

http://publicationslist.org/Ulf.Lindh/refid36 2008-06-15T16:37:43Z

The significantly increased concentrations of granulocyte manganese in subjects with AIP may be an indication of overexpression of manganese-associated enzymes. In this study we present further observations related to this phenomenon and speculate that this may provide a rational basis for hypotheses attempting to explain the pathogenesis of the acute attack of porphyria. Such hypotheses are advan...<br/><br/>S Thunell, Y Floderus, P Harper, A Henrichson, U Lindh, S Marklund (1997) <i>Cell Mol Biol (Noisy-le-grand)</i> <i></i> <i></i> 43: 1 1-8<br/>

http://publicationslist.org/Ulf.Lindh/refid37 2008-06-15T16:37:43Z

Genetic factors are major contributors in determining the susceptibility to systemic autoimmune diseases. We studied the influence of genotype on systemic autoimmunity by treating female mice of the H-2s strains SJL/N, SJL/J, A.SW, and B10.S with mercuric chloride (HgCl2) for 10 weeks and then following autoantibody and tissue immune deposits during the subsequent 12 months. All strains developed ...<br/><br/>P Hultman, S J Turley, S Eneström, U Lindh, K M Pollard (1996) <i>J Autoimmun</i> <i></i> <i></i> 9: 2 139-149<br/>

http://publicationslist.org/Ulf.Lindh/refid38 2008-06-15T16:37:43Z

Interaction between selenium and the heavy metals cadmium and mercury was studied in an experimental rat model (Sprague-Dawley). The rats were administered either one single trace element or combinations of selenium and cadmium as well as selenium and mercury. Salts of these trace elements were administered intraperitoneally daily during thirty days. Thereafter the animals were sacrificed and kidn...<br/><br/>U Lindh, A Danersund, A Lindvall (1996) <i>Cell Mol Biol (Noisy-le-grand)</i> <i></i> <i></i> 42: 1 39-48<br/>

http://publicationslist.org/Ulf.Lindh/refid41 2008-06-15T16:37:56Z

X-ray microanalysis was used to detect elemental changes in the insulin-producing tumor cell-line RINm5F. To improve discrimination between mobile ions and ions bound to macromolecules a new approach was employed, consisting of multivariate statistical analysis of correlations between the concentrations of Na, Mg, P, S, Cl, K, and Ca. RINm5F cells, cultured on Formvar-coated titanium grids, were s...<br/><br/>E Pålsgård, U Lindh, L Juntti-Berggren, P O Berggren, G M Roomans (1995) <i>Cell Biol Int</i> <i></i> <i></i> 19: 1 25-34<br/>

http://publicationslist.org/Ulf.Lindh/refid40 2008-06-15T16:37:43Z

Previously symptomatic and permanently asymptomatic carriers of a gene mutation for acute intermittent porphyria as well as matched controls were screened with regard to a series of variables of possible relevance to the development of porphyric symptoms. The basis for the study was a concept of acute porphyria as a condition of a permanent system overload of oxidative stress, with long term effec...<br/><br/>S Thunell, C Andersson, B Carlmark, Y Floderus, S O Grönqvist, P Harper, A Henrichson, U Lindh (1995) <i>Eur J Clin Chem Clin Biochem</i> <i></i> <i></i> 33: 4 179-194<br/>

http://publicationslist.org/Ulf.Lindh/refid39 2008-06-15T16:37:43Z

The magnitude of inflammatory lesions in the hearts of coxsackie B3 (CB3)-virus infected mice can be affected by the potentially toxic heavy metals cadmium (Cd), nickel (Ni) and methyl mercury (MeHg). The infection is associated with a changed distribution, such as Cd accumulation in the spleen and kidneys. New target organs for Ni during the infection were the heart, pancreas and lungs in which i...<br/><br/>N G Ilbäck, U Lindh, J Fohlman, G Friman (1995) <i>Eur Heart J</i> <i></i> <i></i> 16 Suppl O: 20-24<br/>

http://publicationslist.org/Ulf.Lindh/refid43 2008-06-15T16:37:56Z

A comparative study of some aspects of freeze-substitution as a preparative method for X-ray microanalysis of diffusible ions in biological specimens was carried out. Four substitution fluids were compared with each other and with cryosections. As criteria, elemental ratios as determined by X-ray microanalysis of thin sections of mouse pancreas were used. Freeze-substitution for 3 weeks in diethyl...<br/><br/>E Pålsgård, U Lindh, G M Roomans (1994) <i>Microsc Res Tech</i> <i></i> <i></i> 28: 3 254-258<br/>

http://publicationslist.org/Ulf.Lindh/refid44 2008-06-15T16:37:56Z

Elemental redistribution induced by insulin secretion, was investigated by electron and proton probe X-ray microanalysis. In particular, ion fluxes following immediately upon stimulation were studied. As the sensitivity of the electron probe was insufficient, the proton microprobe was employed. In order to see whether the cell is asymmetric with respect to Ca2+ influx, the cells were stimulated in...<br/><br/>E Pålsgård, U Lindh, L Juntti-Berggren, P O Berggren, G M Roomans, G W Grime (1994) <i>Scanning Microsc Suppl</i> <i></i> <i></i> 8: 325-32; discussion 332-3<br/>

http://publicationslist.org/Ulf.Lindh/refid42 2008-06-15T16:37:56Z

Dental amalgam fillings are the most important source of mercury exposure in the general population, but their potential to cause systemic health consequences is disputed. In this study, inbred mice genetically susceptible to mercury-induced immune aberrations were used to examine whether dental amalgam may interfere with the immune system and cause autoimmunity. Female SJL/N mice were implanted i...<br/><br/>P Hultman, U Johansson, S J Turley, U Lindh, S Eneström, K M Pollard (1994) <i>FASEB J</i> <i></i> <i></i> 8: 14 1183-1190<br/>

http://publicationslist.org/Ulf.Lindh/refid45 2008-06-15T16:37:56Z

To clarify whether elemental changes are present before the onset of diabetes, freeze-dried pancreas sections from young (18-19 days old), genetically prediabetic Chinese hamsters were subjected to proton bombardment and the concentrations of 15 elements (Na, Mg, Al, P, S, Cl, K, Ca, Mn, Fe, Cu, Zn, Rb, Cd, and Pb) in B cells and exocrine pancreas were calculated from the x-rays emitted. We have p...<br/><br/>L Juntti-Berggren, U Lindh, P O Berggren, B J Frankel (1992) <i>Pancreas</i> <i></i> <i></i> 7: 1 11-14<br/>

http://publicationslist.org/Ulf.Lindh/refid48 2008-06-15T16:37:56Z

Mice were injected intravenously with lead chloride, 75 micrograms/g body weight. The mice were in an experimental delay of implantation, which offered the functionally steady conditions required for developing the testing procedures. One day after the administration of lead, blastocysts were flushed from the uterine cavity, placed on thin foils of Kapton, and air-dried. The dried blastocysts were...<br/><br/>B O Nilsson, U Lindh, T Sunde, M Wide (1991) <i>Reprod Toxicol</i> <i></i> <i></i> 5: 1 53-55<br/>

http://publicationslist.org/Ulf.Lindh/refid47 2008-06-15T16:37:56Z

The concentrations of electrolytes and trace elements in erythrocytes were determined in eight children with cystic fibrosis (CF) and the parents of four of the children and compared with age- and sex-matched healthy controls. The children with CF had significantly lower median erythrocyte concentrations of sodium, magnesium and zinc and a higher median concentration of calcium than both the healt...<br/><br/>T Foucard, M Gebre-Medhin, K H Gustavson, U Lindh (1991) <i>Acta Paediatr Scand</i> <i></i> <i></i> 80: 1 57-61<br/>

http://publicationslist.org/Ulf.Lindh/refid46 2008-06-15T16:37:56Z

By using the proton microprobe technique we have investigated the elemental composition of both pancreatic beta-cells and exocrine pancreas from fed and 24 h or 48 h starved obese hyperglycemic mice. Among the 15 elements measured in the beta-cells both Ca and Fe increased while Mg and S decreased significantly after 24 h of starvation, the effects being more pronounced after 48 h. When animals we...<br/><br/>L Juntti-Berggren, U Lindh, P O Berggren (1991) <i>Biosci Rep</i> <i></i> <i></i> 11: 2 73-84<br/>

http://publicationslist.org/Ulf.Lindh/refid52 2008-06-15T16:38:12Z

Female rats were given single intraperitoneal doses of fluoride (F) (0, 4, 7, or 14 mg F/kg body weight). Plasma F levels returned to predose values within 24 h. Incisors from animals killed 35 or 70 days after the F doses had been given were analyzed for mineralization defects by microradiography, and for F and P concentrations by nuclear microprobe. At 35 days, all F-injected rats had enamel flu...<br/><br/>B Angmar-Månsson, U Lindh, G M Whitford (1990) <i>Caries Res</i> <i></i> <i></i> 24: 4 258-262<br/>

http://publicationslist.org/Ulf.Lindh/refid51 2008-06-15T16:38:12Z

Freeze-dried pancreas sections from 7-, 17- and 27-week-old genetically diabetic (db/db) and normal (+/-/+/-) mice were subjected to proton bombardment and the concentrations of 15 elements in B cells and exocrine pancreas were calculated from the characteristic X-rays emitted. In the 7-week-old diabetic animals, B cells contained significantly above-normal levels of Na and S, while exocrine pancr...<br/><br/>L Juntti-Berggren, U Lindh, P O Berggren, O Berglund, B J Frankel (1990) <i>Biosci Rep</i> <i></i> <i></i> 10: 2 217-223<br/>

http://publicationslist.org/Ulf.Lindh/refid49 2008-06-15T16:37:56Z

The elemental profiles of thrombocytes and mononuclear cells were investigated in five patients with Infantile and eight with Juvenile Neuronal Ceroid Lipofuscinosis. The patients with the infantile form had suffered from the disease for a year and those with the juvenile form for some six years. The thrombocytes exhibited increased concentrations of calcium and magnesium, but the same concentrati...<br/><br/>E Johansson, U Lindh, T Westermarck, H Heiskala, P Santavuori (1990) <i>J Trace Elem Electrolytes Health Dis</i> <i></i> <i></i> 4: 3 139-142<br/>

http://publicationslist.org/Ulf.Lindh/refid50 2008-06-15T16:37:56Z

Twenty Swedish Landrace lambs were divided randomly into two equal groups, group I and group O. Group I received approximately 0.1 mg selenium as sodium selenite per day and group O 0.1 mg selenium as selenium in yeast per day. The animals were fed per day 1.2-1.5 kg of hay and 0.3 kg of a commercial concentrate supplemented with vitamins and minerals. The trial lasted 3.5 months. As monitored by ...<br/><br/>E Johansson, S O Jacobsson, J Luthman, U Lindh (1990) <i>Zentralbl Veterinarmed A</i> <i></i> <i></i> 37: 6 463-470<br/>

http://publicationslist.org/Ulf.Lindh/refid53 2008-06-15T16:38:12Z

The mass fraction of certain elements was measured in isolated granulocytes and isolated granulocyte granule fractions from patients with active inflammatory arthritides (N = 6) and healthy controls (N = 6). The patients had significantly increased amounts of Ca in the granulocytes, in the specific and light azurophil granules, but normal Ca amounts in the dense azurophil granules. Sr was below th...<br/><br/>R Hällgren, N Feltelius, R Garcia, P Venge, U Lindh (1989) <i>Inflammation</i> <i></i> <i></i> 13: 4 383-392<br/>

http://publicationslist.org/Ulf.Lindh/refid54 2008-06-15T16:38:12Z

The distribution of lead in the cerebellum of suckling Sprague-Dawley rats was examined using a nuclear microprobe for elemental mapping of tissue sections (particle-induced X-ray emission, 3-microns beam of 2.5 MeV protons; micro-PIXE). The rats were injected intraperitoneally with a lead-containing vehicle or vehicle only from ages 1 to 14 days. The calculated doses were 7.8 (low-dose) and 15.6 ...<br/><br/>U Lindh, N G Conradi, P Sourander (1989) <i>Acta Neuropathol</i> <i></i> <i></i> 79: 2 149-153<br/>

http://publicationslist.org/Ulf.Lindh/refid55 2008-06-15T16:38:12Z

Subjectively healthy HLA-B27 positive 1st degree relatives (n = 14) of patients with ankylosing spondylitis (AS) were investigated concerning the mass fraction of calcium (Ca), magnesium (Mg), manganese (Mn), iron (Fe), zinc (Zn), strontium (Sr) and copper (Cu) in isolated blood cells using the nuclear microprobe technique. No relative had laboratory signs of inflammatory disease defined by acute ...<br/><br/>N Feltelius, R Hällgren, U Lindh (1988) <i>J Rheumatol</i> <i></i> <i></i> 15: 2 308-314<br/>

http://publicationslist.org/Ulf.Lindh/refid56 2008-06-15T16:38:12Z

The mass fraction of calcium (Ca), magnesium (Mg), manganese (Mn), iron (Fe). zinc (Zn), strontium (Sr) and copper (Cu) in isolated granulocytes, erythrocytes and platelets was measured using the nuclear microprobe technique. The cellular profile of metal variation was conspiciously altered in patients (n = 29) with ankylosing spondylitis compared with the profile found in age and sex matched heal...<br/><br/>R Hällgren, N Feltelius, U Lindh (1987) <i>J Rheumatol</i> <i></i> <i></i> 14: 3 548-553<br/>

http://publicationslist.org/Ulf.Lindh/refid57 2008-06-15T16:38:12Z

Diabetes mellitus spontaneously develops in certain sublines of non-obese Chinese hamsters, and the diabetic L-subline is known for subnormal pancreatic insulin release in vitro. The cause of the secretory defect is unknown. Freeze-dried pancreas sections from genetically diabetic Chinese hamsters and normal controls were subjected to proton bombardment and the concentration of 15 elements in B ce...<br/><br/>L Juntti-Berggren, U Lindh, P O Berggren, B J Frankel (1987) <i>Biosci Rep</i> <i></i> <i></i> 7: 1 33-41<br/>

http://publicationslist.org/Ulf.Lindh/refid59 2008-06-15T16:38:12Z

K Svenson, R Hällgren, E Johansson, U Lindh (1986) <i>Acta Pharmacol Toxicol (Copenh)</i> <i></i> <i></i> 59 Suppl 7: 386-391<br/>

http://publicationslist.org/Ulf.Lindh/refid58 2008-06-15T16:38:12Z

The cellular stores of iron in granulocytes and platelets isolated from 29 patients with ankylosing spondylitis were measured by the nuclear microprobe technique. The mean iron content in polymorphonuclear cells (PMNs) was 32 (SD 3) micrograms/g dry weight and in platelets 11 (2.6) micrograms/g dry weight. Corresponding values for age and sex matched healthy controls were 5.2 (1.9) and 4.6 (0.8) m...<br/><br/>N Feltelius, U Lindh, P Venge, R Hällgren (1986) <i>Ann Rheum Dis</i> <i></i> <i></i> 45: 10 827-831<br/>

http://publicationslist.org/Ulf.Lindh/refid64 2008-06-15T16:38:22Z

Freeze-dried pancreas sections from obese-hyperglycemic mice were subjected to proton bombardment and the elemental contents in the beta-cells and the exocrine part were obtained from the characteristic X-rays emitted. Quantitative data were provided for 18 different elements. The mole ratio between K and Na exceeded 10, implying that neither the sample preparation nor the irradiation had induced ...<br/><br/>U Lindh, L Juntti-Berggren, P O Berggren, B Hellman (1985) <i>Biomed Biochim Acta</i> <i></i> <i></i> 44: 1 55-61<br/>

http://publicationslist.org/Ulf.Lindh/refid63 2008-06-15T16:38:22Z

The mass fraction of Ca and Mg in isolated erythrocytes and granulocytes was measured using the nuclear microprobe technique. Conspicuous abnormalities were observed in cells from patients with rheumatoid arthritis and other inflammatory arthritides. Compared with the normal cellular content, total Ca was increased an average of 3 times in erythrocytes and 5 times in granulocytes. Total granulocyt...<br/><br/>R Hällgren, K Svenson, E Johansson, U Lindh (1985) <i>Arthritis Rheum</i> <i></i> <i></i> 28: 2 169-173<br/>

http://publicationslist.org/Ulf.Lindh/refid62 2008-06-15T16:38:22Z

The concentrations of trace elements in three different types of blood cells--erythrocytes, thrombocytes and neutrophils--were determined by nuclear microprobe analysis in 11 children with Down's syndrome (DS) and compared with those in 13 controls. The median concentration of copper in all three types of blood cells and that of calcium in erythrocytes were significantly higher in DS children than...<br/><br/>G Annerén, E Johansson, U Lindh (1985) <i>Acta Paediatr Scand</i> <i></i> <i></i> 74: 2 259-263<br/>

http://publicationslist.org/Ulf.Lindh/refid60 2008-06-15T16:38:12Z

Higher than normal amounts (p less than 0.001) of manganese were found in granulocytes isolated from patients with rheumatoid arthritis, other inflammatory arthritides, and scleroderma, while erythrocytes and platelets contained normal amounts of manganese. The cause of manganese accumulation is not known but evidently is linked to the intensity of the inflammatory process since significant positi...<br/><br/>R Hällgren, K Svenson, E Johansson, U Lindh (1985) <i>J Rheumatol</i> <i></i> <i></i> 12: 5 876-880<br/>

http://publicationslist.org/Ulf.Lindh/refid61 2008-06-15T16:38:22Z

By the use of the nuclear microprobe technique, the concentrations of zinc in isolated erythrocytes, platelets, and granulocytes were measured in patients with rheumatoid arthritis, other inflammatory arthritides, and scleroderma. Markedly reduced cellular zinc values were found compared to those measured in healthy subjects. No relation was found to inflammatory activity or disease duration. Plas...<br/><br/>K L Svenson, R Hällgren, E Johansson, U Lindh (1985) <i>Inflammation</i> <i></i> <i></i> 9: 2 189-199<br/>

http://publicationslist.org/Ulf.Lindh/refid65 2008-06-15T16:38:22Z

Total cellular strontium and calcium were measured by the nuclear microprobe technique. Increased mass fraction of both elements was found in granulocytes isolated from patients with active rheumatoid arthritis and other kinds of inflammatory arthritides. Increased granulocyte calcium but only marginally elevated granulocyte strontium was demonstrated in patients with scleroderma. The granulocyte ...<br/><br/>R Hällgren, K Svensson, E Johansson, U Lindh (1984) <i>J Lab Clin Med</i> <i></i> <i></i> 104: 6 893-900<br/>

http://publicationslist.org/Ulf.Lindh/refid66 2008-06-15T16:38:22Z

E Johansson, U Lindh, T Alanen, T Westermarck, H Heiskala, P Santavuori, I Elovaara (1984) <i>Med Biol</i> <i></i> <i></i> 62: 2 139-142<br/>

http://publicationslist.org/Ulf.Lindh/refid67 2008-06-15T16:38:22Z

U Lindh, E Johansson (1983) <i>Neurotoxicology</i> <i></i> <i></i> 4: 3 177-188<br/>

http://publicationslist.org/Ulf.Lindh/refid68 2008-06-15T16:38:22Z

U Lindh, D Brune, G Nordberg, P O Wester (1981) <i>Sci Total Environ</i> <i></i> <i></i> 20: 1 3-11<br/>

http://publicationslist.org/Ulf.Lindh/refid71 2008-06-15T16:38:33Z

Proton microprobe analysis was used to determine the fluoride concentrations in enamel and dentin surfaces exposed to a fluoride-containing and a conventional amalgam in vitro. After seven weeks of exposure, a considerable fluoride uptake was demonstrated from the fluoride-containing amalgam. The fluoride deposition was greater in the dentin than in the enamel. The greatest fluoride concentrations...<br/><br/>A B Tveit, U Lindh (1980) <i>Acta Odontol Scand</i> <i></i> <i></i> 38: 5 279-283<br/>

http://publicationslist.org/Ulf.Lindh/refid70 2008-06-15T16:38:22Z

The contents of the elements antimony, arsenic, cadmium, copper, lead, mercury, selenium, silver, tin and zinc in bone tissue from autopsy specimens of the femur of workers who had been exposed to a large number of metals in a smeltery and refinery in Northern Sweden as well as of a control group have been quantitatively assayed. The analytical techniques used were atomic absorption spectrophotome...<br/><br/>U Lindh, D Brune, G Nordberg, P O Wester (1980) <i>Sci Total Environ</i> <i></i> <i></i> 16: 2 109-116<br/>

http://publicationslist.org/Ulf.Lindh/refid69 2008-06-15T16:38:22Z

U Lindh (1980) <i>Int J Appl Radiat Isot</i> <i></i> <i></i> 31: 12 737-746<br/>

http://publicationslist.org/Ulf.Lindh/refid72 2008-06-15T16:38:33Z

A method is described for the measurement of the distribution of lead in bone tissue. Two cases of human femur have been analyzed; one worker was exposed to lead in heavy metal industry, the other case presents a reference worker from the same environment not excessively exposed to lead. Lead was determined through proton induced X-ray emission using microprobe technique. The mean lead concentrati...<br/><br/>U Lindh, D Brune, G Nordberg (1978) <i>Sci Total Environ</i> <i></i> <i></i> 10: 1 31-37<br/>