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<feed xmlns="http://www.w3.org/2005/Atom" xml:lang="en"><id>http://publicationslist.org/data/a.m.bassi/atom.xml</id><title>Anna Bassi's Publications List</title>
<link rel="self" type="application/atom+xml" href="http://publicationslist.org/data/a.m.bassi/atom.xml"/><link rel="alternate" type="text/html" href="http://publicationslist.org/a.m.bassi"/><author><name>Anna Bassi</name><uri>http://publicationslist.org/a.m.bassi</uri></author><icon>$basepathfavicon.ico</icon><subtitle>Recent additions to Anna Bassi's PublicationsList.org page</subtitle><logo>http://publicationslist.org/publications.png</logo><updated>2010-01-08T14:34:39Z</updated>

<entry>
<id>http://publicationslist.org/a.m.bassi/refid49</id>
<updated>2010-01-08T13:19:57Z</updated>
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<title type='html'>Modulation of CYP1A1 by PKC Inhibitors and TPA Pre-Treatments in MH1C1 Rat Hepatoma Cells Exposed to 3 –Methylcholanthrene, </title>
<summary type='html'>Cytochrome P4501A1 (CYP1A1), an enzyme known to metabolize polycyclic aromatic hydrocarbons, is regulated by the aryl hydrocarbon receptor (AhR). The involvement of protein kinase C (PKC) in the regulation of AhR signal transduction pathway, has been widely studied but the role of specific PKC isoform(s) involved in this process it is not well clarified. To study which PKC isoform(s) is implicated...&lt;br/&gt;&lt;br/&gt;De Pascale C, Domenicotti C ,   Nitti M, Marengo B,  Catalano M, Scanarotti C, Sanguineti R, Siri M, Ledda S,  Penco S, Bassi A M.   (2009)  &lt;i&gt;The Open Toxicology Journal &lt;/i&gt; 3:  45-57&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid3</id>
<updated>2010-01-08T13:17:27Z</updated>
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<title type='html'>Salvia somalensis essential oil as a potential cosmetic ingredient: solvent-free microwave extraction, hydrodistillation, GC-MS analysis, odour evaluation and in vitro cytotoxicity assays.</title>
<summary type='html'>Salvia somalensis Vatke, a wild sage native of Somalia, has been studied with the aim of assessing the potential cosmetic application of its essential oil, recovered from fresh aerial parts by solvent-free microwave extraction - SFME. To evaluate the efficiency and reliability of this eco-friendly procedure, the recovery of the essential oil was also processed by conventional hydrodistillation (HD...&lt;br/&gt;&lt;br/&gt;C Villa, B Trucchi, A Bertoli, L Pistelli, A Parodi, A M Bassi, B Ruffoni (2009)  &lt;i&gt;Int J Cosmet Sci&lt;/i&gt; 31: 1 55-61&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid2</id>
<updated>2010-01-08T13:17:10Z</updated>
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<title type='html'>Pre-adipocytes commitment to neurogenesis 1: preliminary localisation of cholinergic molecules.</title>
<summary type='html'>A great effort has recently been made to obtain human stem cells able to differentiate into cholinergic neurons, as a number of diseases are associated to the cholinergic neuron loss, degeneration or incorrect function (Alzheimer's disease and motor neuron disease). A stem cell population (i.e. pre-adipocytes) is present in the adipose stromal compartment. Pre-adipocytes, like the mesodermic deriv...&lt;br/&gt;&lt;br/&gt;Maria Grazia Aluigi, Rosella Coradeghini, Chiara Guida, Chiara Scanarotti, Anna Maria Bassi, Carla Falugi, PierLuigi Santi, Edoardo Raposio (2009)  &lt;i&gt;Cell Biol Int&lt;/i&gt; 33: 5 594-601&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid1</id>
<updated>2010-01-08T12:25:55Z</updated>
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<title type='html'>A Comparative Study of Proliferation and Hepatic Differentiation of Human Adipose-Derived Stem Cells.</title>
<summary type='html'>Human adipose-derived stem cells possess a lot of stem cell characteristics, so they may be considered a source of stem cell population. On the basis of that, we have investigated the hepatic potential of adipose-derived stem cells, obtained from liposuction, following two differentiation protocols. In the first procedure, medium was supplemented with epidermal growth factor (EGF), basic fibroblas...&lt;br/&gt;&lt;br/&gt;R Coradeghini, C Guida, C Scanarotti, R Sanguineti, A M Bassi, A Parodi, P L Santi, E Raposio (2009)  &lt;i&gt;Cells Tissues Organs&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; :  &lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid5</id>
<updated>2010-01-08T13:20:44Z</updated>
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<title type='html'>Comparison of the irritation potentials of Boswellia serrata gum resin and of acetyl-11-keto-beta-boswellic acid by in vitro cytotoxicity tests on human skin-derived cell lines.</title>
<summary type='html'>Indian frankincense is a gum resin from Boswellia serrata of Burseraceae used in Ayurveda and Western medicine for the antinflammatory effects of boswellic acids, particularly 3-O-acetyl-11-keto-beta-boswellic acid (AKBA). We evaluated in vitro cytotoxicities of B. serrata extract and AKBA on differentiated and undifferentiated keratinocytes (HaCaT and NCTC 2544), and foetal dermal fibroblasts (HF...&lt;br/&gt;&lt;br/&gt;Bruno Burlando, Alessandro Parodi, Andrea Volante, Anna Maria Bassi (2008)  &lt;i&gt;Toxicol Lett&lt;/i&gt; 177: 2 144-149&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid6</id>
<updated>2010-01-08T13:22:45Z</updated>
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<title type='html'>Antioxidant activity of timolol on endothelial cells and its relevance for glaucoma course.</title>
<summary type='html'>PURPOSE: A growing evidence in the scientific literature suggests that oxidative damage plays a pathogenic role in primary open-angle glaucoma. Therefore, it is of interest to test whether drugs effective against glaucoma display antioxidant activity. We test the hypothesis that the classic beta-blocker therapy for glaucoma with timolol involves the activation of antioxidant protective mechanisms ...&lt;br/&gt;&lt;br/&gt;A Izzotti, S C Saccà, B Di Marco, S Penco, A M Bassi (2008)  &lt;i&gt;Eye (Lond)&lt;/i&gt; 22: 3 445-453&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid4</id>
<updated>2010-01-08T13:23:23Z</updated>
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<title type='html'>3,3,5-Trimethylcyclohexanols and derived esters: green synthetic procedures, odour evaluation and in vitro skin cytotoxicity assays(1).</title>
<summary type='html'>The alcohols 3,3,5-trimethylcyclohexanols (cis, trans epimers, cosmetic fragrance) and some derived esters, potential and well-known actives in the cosmetic field, such as Homosalate, were synthesized using fast solvent-free methodologies with the aim of renewing and simplifying the conventional procedures. The alcohols were prepared by reduction of 3,3,5-trimethylcyclohexanone (dihydroisophorone)...&lt;br/&gt;&lt;br/&gt;R Gambaro, C Villa, S Baldassari, E Mariani, A Parodi, A M Bassi (2006)  &lt;i&gt;Int J Cosmet Sci&lt;/i&gt; 28: 6 439-446&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid8</id>
<updated>2010-01-08T13:25:46Z</updated>
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<title type='html'>Rat HMGCoA reductase activation in thioacetamide-induced liver injury is related to an increased reactive oxygen species content.</title>
<summary type='html'>BACKGROUND/AIMS: In thioacetamide-induced liver injury a modification of isoprenoid content and an increase of reactive oxygen species has been described. We have examined how reactive oxygen species influence the 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate limiting enzyme of the isoprenoid biosynthetic pathway, to verify if changes of that enzyme activity are involved in the changed...&lt;br/&gt;&lt;br/&gt;Valentina Pallottini, Chiara Martini, Anna M Bassi, Paola Romano, Giorgio Nanni, Anna Trentalance (2006)  &lt;i&gt;J Hepatol&lt;/i&gt; 44: 2 368-374&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid7</id>
<updated>2010-01-08T13:24:09Z</updated>
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<title type='html'>Increased expression of transglutaminase-1 and PPARgamma after vitamin E treatment in human keratinocytes.</title>
<summary type='html'>In skin, vitamin E acts as the predominant lipophilic antioxidant with a protective function against irradiation and oxidative stress. In addition to that, vitamin E can also modulate signal transduction and gene expression. To study whether the four natural tocopherol analogues (alpha-, beta-, gamma-, delta-tocopherol) can influence transcriptional activity by modulating the activity of nuclear r...&lt;br/&gt;&lt;br/&gt;M Clara De Pascale, Anna Maria Bassi, Vania Patrone, Luis Villacorta, Angelo Azzi, Jean-Marc Zingg (2006)  &lt;i&gt;Arch Biochem Biophys&lt;/i&gt; 447: 2 97-106&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid20</id>
<updated>2010-01-08T12:57:32Z</updated>
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<title type='html'>Chronic high doses of thioacetamide followed by vitamin A modify dolichol, dolichol isoprenoids, and retinol content in rat liver cells.</title>
<summary type='html'>Our line of researches follows the hypothesis that dolichol and retinol metabolism might be interrelated and involved in liver fibrosis. To this end, in this study rats were subjected to chronic treatment with thioacetamide (TAA) (300 mg/L liquid diet) for 1 and 2 months and, after liver damage had occurred, supplemented with vitamin A before sacrifice. Dolichol, dolichol isoprene units, and retin...&lt;br/&gt;&lt;br/&gt;Anna Maria Bassi, Anna Casu, Claudio Canepa, Giuseppe Maloberti, Giorgio Nanni (2005)  &lt;i&gt;Drug Chem Toxicol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 28: 1 91-104&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid9</id>
<updated>2010-01-08T12:25:55Z</updated>
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<title type='html'>Protein and m-RNA expression of farnesyl-transferases, RhoA and RhoB in rat liver hepatocytes: action of perillyl alcohol and vitamin A in vivo.</title>
<summary type='html'>We analysed the action, in rats in vivo, of the protein isoprenylation inhibitor perillyl alcohol (POH) and that of vitamin A, alone or in association, on m-RNA and protein expression of farnesyltransferases (FTases alpha and beta subunits) and their protein substrates RhoA and RhoB, in isolated hepatocytes. Combined administration of POH and vitamin A induced a sharp decrease in FTase alpha prote...&lt;br/&gt;&lt;br/&gt;A M Bassi, P Romano, S Mangini, M Colombo, C Canepa, G Nanni, A Casu (2005)  &lt;i&gt;J Biomed Sci&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 12: 3 457-466&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid19</id>
<updated>2010-01-08T12:57:32Z</updated>
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<title type='html'>Antioxidant status in J774A.1 macrophage cell line during chronic exposure to glycated serum.</title>
<summary type='html'>Advanced glycation end-products (AGEs) are linked to aging and correlated diseases. The aim of present study was to evaluate oxidative stress related parameters in J774A.1 murine macrophage cells during chronic exposure to a subtoxic concentration of AGE (5% ribose-glycated serum (GS)) and subsequently for 48 h to a higher dose (10% GS). No effects on cell viability were evident in either experime...&lt;br/&gt;&lt;br/&gt;Anna Maria Bassi, Sabina Ledda, Maria Clara De Pascale, Susanna Penco, Simona Rossi, Patrizio Odetti, Damiano Cottalasso (2005)  &lt;i&gt;Biochem Cell Biol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 83: 2 176-187&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid22</id>
<updated>2010-01-08T12:57:32Z</updated>
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<title type='html'>Association of thioacetamide and ethanol treatment: dolichol and retinol in isolated rat liver cells.</title>
<summary type='html'>Our aim was to study the distribution of dolichol, dolichol isoprenoids, and retinol in hepatocytes, Kupffer, sinusoidal endothelial and two subfractions of hepatic stellate cells, --Ito-1 and Ito-2--, after chronic treatment of rats for 2 and 4 months with a low dosage of thioacetamide associated with ethanol. Each type of cell responded differently to the two hepatotoxins. Overall, ethanol rarel...&lt;br/&gt;&lt;br/&gt;Anna Maria Bassi, Damiano Cottalasso, Claudio Canepa, Giuseppe Maloberti, Anna Casu, Giorgio Nanni (2004)  &lt;i&gt;Drug Chem Toxicol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 27: 1 55-67&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid21</id>
<updated>2010-01-08T14:29:29Z</updated>
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<title type='html'>Effect of a load of Vitamin A after acute thioacetamide intoxication on dolichol, dolichol isoprenoids and retinol content in isolated rat liver cells.</title>
<summary type='html'>This study examines how treatment with a single dose of thioacetamide, a known experimental hepatotoxin, alters the content of dolichol, dolichol isoprene units and retinol in isolated rat parenchymal and non-parenchymal liver cells at different times and when the animals are supplemented with Vitamin A. Thioacetamide (300 mg/kg i.p.) was administered in a single injection to rats, sacrificed at i...&lt;br/&gt;&lt;br/&gt;Anna M Bassi, Claudio Canepa, Giuseppe Maloberti, Anna Casu, Giorgio Nanni (2004)  &lt;i&gt;Toxicology&lt;/i&gt; 199: 2-3 97-107&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid23</id>
<updated>2010-01-08T14:30:16Z</updated>
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<title type='html'>Chronic ethanol treatment: dolichol and retinol distribution in isolated rat liver cells.</title>
<summary type='html'>The aim of this study was to use chronic ethanol intoxication for 2 and 4 months as a means of studying the distribution of dolichol and retinol in isolated rat liver parenchymal cells, Kupffer cells, sinusoidal endothelial cells, and two subfractions of hepatic stellate cells: Ito 1 and Ito 2. Dolichol and retinol were studied in two batches of rats: on normal nutrition and after a load of vitami...&lt;br/&gt;&lt;br/&gt;Damiano Cottalasso, Anna Maria Bassi, Claudio Canepa, Giuseppe Maloberti, Anna Casu, Giorgio Nanni (2003)  &lt;i&gt;Free Radic Biol Med&lt;/i&gt; 34: 3 337-344&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid24</id>
<updated>2010-01-08T12:57:32Z</updated>
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<title type='html'>Dolichol content in isolated sinusoidal liver cells after in vivo chronic treatment with thioacetamide.</title>
<summary type='html'>The content of dolichol, an isoprenoid present in all biological membranes, was determined in isolated sinusoidal liver cells after treatment of rats for 2 and 4 months with a low dosage of the hepatotoxin thioacetamide. The significant decrease in dolichol observed in hepatocytes after 2 months might be explained by peroxidation of the isoprenoid. At the same time point, retinol was retained, and...&lt;br/&gt;&lt;br/&gt;Giorgio Nanni, Federica Majorani, Anna Maria Bassi, Claudio Canepa, Giuseppe Maloberti, Anna Casu (2002)  &lt;i&gt;Exp Toxicol Pathol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 54: 1 43-50&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid25</id>
<updated>2010-01-08T14:31:24Z</updated>
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<title type='html'>Thioacetamide impairs retinol storage and dolichol content in rat liver cells in vivo.</title>
<summary type='html'>The aim of this paper was to ascertain whether chronic pretreatment with thioacetamide (TAA) might alter the uptake of a load of retinol and dolichol distribution in hepatocytes (HC), hepatic stellate cells (HSC) (Ito-1 and Ito-2 subfractions), Kupffer (KC) and sinusoidal endothelial cells (SEC). The reason why retinol and dolichol content was studied is that their metabolism and transport might b...&lt;br/&gt;&lt;br/&gt;A Casu, A M Bassi, C Canepa, G Maloberti, G Nanni (2002)  &lt;i&gt;Biochim Biophys Acta&lt;/i&gt; 1583: 3 266-272&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid26</id>
<updated>2010-01-08T14:32:24Z</updated>
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<title type='html'>Damaging effects of advanced glycation end-products in the murine macrophage cell line J774A.1.</title>
<summary type='html'>The interaction of reducing sugars, such as aldose, with proteins and the subsequent molecular rearrangements, produces irreversible advanced glycation end-products (AGEs), a heterogeneous class of non-enzymatic glycated proteins or lipids. AGEs form cross-links, trap macromolecules and release reactive oxygen intermediates. AGEs are linked to aging, and increase in several related diseases. The a...&lt;br/&gt;&lt;br/&gt;A M Bassi, S Ledda, S Valentini, M C De Pascale, S Rossi, P Odetti, D Cottalasso (2002)  &lt;i&gt;Toxicol In Vitro&lt;/i&gt; 16: 4 339-347&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid27</id>
<updated>2010-01-08T12:57:32Z</updated>
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<title type='html'>Increase in class 2 aldehyde dehydrogenase expression by arachidonic acid in rat hepatoma cells.</title>
<summary type='html'>Aldehyde dehydrogenase (ALDH) is a family of several isoenzymes important in cell defence against both exogenous and endogenous aldehydes. Compared with normal hepatocytes, in rat hepatoma cells the following changes in the expression of ALDH occur: cytosolic class 3 ALDH expression appears and mitochondrial class 2 ALDH decreases. In parallel with these changes, a decrease in the polyunsaturated ...&lt;br/&gt;&lt;br/&gt;R A Canuto, M Ferro, R A Salvo, A M Bassi, A Trombetta, M Maggiora, G Martinasso, R Lindahl, G Muzio (2001)  &lt;i&gt;Biochem J&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 357: Pt 3 811-818&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid28</id>
<updated>2010-01-08T14:34:26Z</updated>
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<title type='html'>Changes of CYP1A1, GST, and ALDH3 enzymes in hepatoma cell lines undergoing enhanced lipid peroxidation.</title>
<summary type='html'>Hepatoma cells show alterations in the response to oxidative stress (decreased lipid peroxidation) and in xenobiotic metabolism enzymes (decreased P450, increased GST and ALDH3). This study examined the effect of lipid peroxidation on the expression of the above enzymes in two rat hepatoma cell lines (MH(1)C(1) and 7777). To induce oxidative stress, cells were exposed to arachidonic acid (to incre...&lt;br/&gt;&lt;br/&gt;A M Bassi, S Ledda, S Penco, S Menini, G Muzio, R Canuto, M Ferro (2000)  &lt;i&gt;Free Radic Biol Med&lt;/i&gt; 29: 11 1186-1196&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid30</id>
<updated>2010-01-08T12:58:10Z</updated>
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<title type='html'>Effect of arachidonic acid alone or with prooxidant on aldehyde dehydrogenases in hepatoma cells.</title>
<summary type='html'>R A Canuto, M Ferro, R A Salvo, A M Bassi, M Terreno, M U Dianzani, R Lindahl, G Muzio (1999)  &lt;i&gt;Adv Exp Med Biol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 463:  133-142&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid31</id>
<updated>2010-01-08T12:58:10Z</updated>
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<title type='html'>Inhibition of class-3 aldehyde dehydrogenase and cell growth by restored lipid peroxidation in hepatoma cell lines.</title>
<summary type='html'>Hepatoma cells have a below-normal content of polyunsaturated fatty acids; this reduces lipid peroxidation and the production of cytotoxic and cytostatic aldehydes within the cells. In proportion to the degree of deviation, hepatoma cells also show an increase in the activity of Class-3 aldehyde dehydrogenase, an enzyme important in the metabolism of lipid peroxidation products and also in that of...&lt;br/&gt;&lt;br/&gt;R A Canuto, G Muzio, M Ferro, M Maggiora, R Federa, A M Bassi, R Lindahl, M U Dianzani (1999)  &lt;i&gt;Free Radic Biol Med&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 26: 3-4 333-340&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid29</id>
<updated>2010-01-08T12:58:10Z</updated>
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<title type='html'>Susceptibility of hepatoma cells to lipid peroxidation and adaptation of ALDH 3C activity to iron-induced oxidative stress.</title>
<summary type='html'>M Ferro, A M Bassi, S Penco, G Muzio, R A Canuto (1999)  &lt;i&gt;Adv Exp Med Biol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 463:  171-179&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid34</id>
<updated>2010-01-08T12:58:10Z</updated>
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<title type='html'>In hepatoma cell lines restored lipid peroxidation affects cell viability inversely to aldehyde metabolizing enzyme activity.</title>
<summary type='html'>R A Canuto, M Ferro, M Maggiora, R Federa, O Brossa, A M Bassi, R Lindahl, G Muzio (1997)  &lt;i&gt;Adv Exp Med Biol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 414:  113-122&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid32</id>
<updated>2010-01-08T12:58:10Z</updated>
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<title type='html'>Comparative evaluation of cytotoxicity and metabolism of four aldehydes in two hepatoma cell lines.</title>
<summary type='html'>The metabolism of acetaldehyde (ACA), benzaldehyde (BA), propionaldehyde (PA) and valeraldehyde (VA) has been studied in two hepatoma cell lines, the rat HTC and mouse Hepa 1c1c7 cells. The cytotoxicity of the four aldehydes to these two cell lines has been compared. The end-points for evaluating cytotoxicity were 1) total macromolecular content (TMC) of confluent cultures, and 2) colony forming a...&lt;br/&gt;&lt;br/&gt;A M Bassi, S Penco, R A Canuto, G Muzio, M Ferro (1997)  &lt;i&gt;Drug Chem Toxicol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 20: 3 173-187&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid38</id>
<updated>2010-01-08T12:58:10Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid38'/>
<title type='html'>Enrichment with arachidonic acid increases the sensitivity of hepatoma cells to the cytotoxic effects of oxidative stress.</title>
<summary type='html'>Hepatoma cells are, at most, moderately sensitive to oxidative stress. An important cause of this lack of sensitivity is the decreased content of polyunsaturated fatty acids in comparison with normal cells. These fatty acids are one cellular target of oxygen radicals, by which they are broken down into several toxic carbonyl compounds. If the membrane phospholipids of tumor cells are enriched with...&lt;br/&gt;&lt;br/&gt;R A Canuto, G Muzio, A M Bassi, M Maggiora, G Leonarduzzi, R Lindahl, M U Dianzani, M Ferro (1995)  &lt;i&gt;Free Radic Biol Med&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 18: 2 287-293&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid40</id>
<updated>2010-01-08T12:59:59Z</updated>
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<title type='html'>Role of aldehyde metabolizing enzymes in mediating effects of aldehyde products of lipid peroxidation in liver cells.</title>
<summary type='html'>It is well established that many types of tumor cells have reduced lipid peroxidation capacity compared to their normal counterparts. Changes in the activity of enzymes metabolizing aldehydes produced by lipid peroxidation have also been reported in a variety of tumor cells. We have investigated the relationship between changes in lipid peroxidation and changes in aldehyde-metabolizing enzymes in ...&lt;br/&gt;&lt;br/&gt;R A Canuto, M Ferro, G Muzio, A M Bassi, G Leonarduzzi, M Maggiora, D Adamo, G Poli, R Lindahl (1994)  &lt;i&gt;Carcinogenesis&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 15: 7 1359-1364&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid39</id>
<updated>2010-01-08T12:59:59Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid39'/>
<title type='html'>Evaluation of the xenobiotic biotransformation capability of six rodent hepatoma cell lines in comparison with rat hepatocytes.</title>
<summary type='html'>Phase I and II activities were examined in six rodent hepatoma cell lines and compared with those of cultured rat hepatocytes both in basal conditions and after exposure to 5 microM methylcholanthrene, 2 mM phenobarbital, and 15 microM beta-naphtoflavone. The metabolic profile of testosterone was also studied. The highest aryl hydrocarbon hydroxylase and 7-ethoxycoumarin O-deethylase activities we...&lt;br/&gt;&lt;br/&gt;M T Donato, A M Bassi, M J Gómez-Lechón, S Penco, E Herrero, D Adamo, J V Castell, M Ferro (1994)  &lt;i&gt;In Vitro Cell Dev Biol Anim&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 30A: 9 574-580&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid41</id>
<updated>2010-01-08T12:59:59Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid41'/>
<title type='html'>Ability of different hepatoma cells to metabolize 4-hydroxynonenal.</title>
<summary type='html'>4-Hydroxynonenal (4-HNE), produced during the oxidative lipid breakdown of biological membranes, modulates various biochemical processes in normal liver and in hepatoma cells. It is very probable that the effects of 4-HNE are related to the quantity formed in the cells and to the cells' ability to metabolize it. Aldehyde catabolism takes place within the cells through oxidative and reductive enzym...&lt;br/&gt;&lt;br/&gt;R A Canuto, G Muzio, M Maggiora, G Poli, F Biasi, M U Dianzani, M Ferro, A M Bassi, S Penco, U M Marinari (1993)  &lt;i&gt;Cell Biochem Funct&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 11: 2 79-86&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid42</id>
<updated>2010-01-08T12:59:59Z</updated>
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<title type='html'>Effects of aldehyde products of lipid peroxidation on the activity of aldehyde metabolizing enzymes in hepatomas.</title>
<summary type='html'>R A Canuto, M Ferro, G Muzio, A M Bassi, G Leonarduzzi, M Maggiora, D Adamo, G Poli, R Lindahl (1993)  &lt;i&gt;Adv Exp Med Biol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 328:  17-25&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid43</id>
<updated>2010-01-08T12:59:59Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid43'/>
<title type='html'>Use of established hepatoma cell lines in biotoxicology.</title>
<summary type='html'>M Ferro, A M Bassi, S Penco, G Nanni (1993)  &lt;i&gt;Cytotechnology&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 11 Suppl 1:  S126-S129&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid44</id>
<updated>2010-01-08T12:59:59Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid44'/>
<title type='html'>Comparative assessment of the cytotoxic effects of different xenobiotics in three hepatoma cell lines.</title>
<summary type='html'>MH1C1, HTC and HEPA 1c1c7 hepatoma cell lines were selected in this study as the bioindicators of the cytotoxicity induced by six chemicals: butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), cycloheximide (CHE), cyclophosphamide (CPA), potassium dichromate (Cr VI) and 2,4-dinitrophenol (DNP). The concentrations used were in the range from 10(-6) mol/l to 10(-2) mol/l, and the exposur...&lt;br/&gt;&lt;br/&gt;M Ferro, A M Bassi, S Penco, S Piana, D Usiglio, G Nanni (1992)  &lt;i&gt;Arzneimittelforschung&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 42: 8 1053-1057&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid48</id>
<updated>2010-01-08T12:59:59Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid48'/>
<title type='html'>Metabolism of 4-hydroxynonenal in hepatoma cell lines.</title>
<summary type='html'>R A Canuto, G Muzio, A M Bassi, M E Biocca, G Poli, H Esterbauer, M Ferro (1991)  &lt;i&gt;Adv Exp Med Biol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 284:  75-84&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid46</id>
<updated>2010-01-08T12:59:59Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid46'/>
<title type='html'>Comparative subcellular distribution of benzaldehyde and acetaldehyde dehydrogenase activities in two hepatoma cell lines and in normal hepatocytes.</title>
<summary type='html'>The NAD- and NADP-dependent aldehyde dehydrogenase (ALDH) activities were evaluated in two rat hepatoma cell lines, namely the well-differentiated MH1C1 line and the less differentiated HTC line. Each activity was determined in parallel in isolated rat hepatocytes, for comparison. The aliphatic aldehyde acetaldehyde (ACA) and the aromatic aldehyde benzaldehyde (BA) were used as substrates. With th...&lt;br/&gt;&lt;br/&gt;M Ferro, G Muzio, A M Bassi, M E Biocca, R A Canuto (1991)  &lt;i&gt;Cell Biochem Funct&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 9: 3 149-154&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid47</id>
<updated>2010-01-08T12:59:59Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid47'/>
<title type='html'>Specific prostatic antigen in prostatic carcinoma: its relationship with tumor differentiation and clinical course</title>
<summary type='html'>Carcinoma of the prostate is a tumor with a variable clinical course and a high incidence of local progression and/or metastasis. This study was undertaken to evaluate tissue prostate specific antigen (PSA) in patients with carcinoma of the prostate, its correlation with Gleason's grading and its value in predicting the clinical course of these patients. We studied 28 transurethral biopsies of pat...&lt;br/&gt;&lt;br/&gt;A M Sáenz de Chirife, A M Bassi, F Celeste, D Bergdolt (1991)  &lt;i&gt;Arch Esp Urol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 44: 4 405-409&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid45</id>
<updated>2010-01-08T12:59:59Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid45'/>
<title type='html'>Use of an established cell line in the evaluation of the cytotoxic effects of various chemicals.</title>
<summary type='html'>The HTC hepatoma cell line was used as an &quot;in vitro&quot; model to detect the cytotoxicity of eighteen chemicals, chosen on the basis of different biological activities and physicochemical characteristics. Two different cytotoxicity assays measuring cell lethality (CS) or inhibition of cell growth (CF) were applicated to confluent cell monolayers or to colony-forming cells, respectively. Cells were exp...&lt;br/&gt;&lt;br/&gt;A M Bassi, S Piana, S Penco, O Bosco, S Brenci, M Ferro (1991)  &lt;i&gt;Boll Soc Ital Biol Sper&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 67: 8 809-816&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid10</id>
<updated>2010-01-08T12:29:47Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid10'/>
<title type='html'>Biochemical properties of carcinogen-metabolizing enzymes in cultured hepatoma cells.</title>
<summary type='html'>We have previously demonstrated the inducibility of both cytochrome P-448- and P-450-dependent monooxygenases in the differentiated rat hepatoma cell line MH1C1. Further experiments with these cells on the expression of different forms of cytochrome P-450, inducible not only by phenobarbital (PB) and 3-methylcholanthrene (MC), but also by metyrapone (MP), ethanol (E), and beta-naphthoflavone (BNF)...&lt;br/&gt;&lt;br/&gt;M Ferro, U M Marinari, A M Bassi, G Nanni (1987)  &lt;i&gt;Toxicol Pathol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 15: 1 97-102&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid13</id>
<updated>2010-01-08T12:29:47Z</updated>
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<title type='html'>Carbon tetrachloride-induced inhibition of hepatocyte lipoprotein secretion: functional impairment of Golgi apparatus in the early phases of such injury.</title>
<summary type='html'>Functional change of liver Golgi apparatus during carbon tetrachloride (CCl4) poisoning was demonstrated both in rat isolated hepatocytes and in the whole animal. The &quot;in vitro&quot; experimental model provided evidence of Golgi derangement early after giving the haloalkane. The &quot;in vivo&quot; analyses also showed that such an alteration involves both formative and secretory sides of the subcellular structu...&lt;br/&gt;&lt;br/&gt;G Poli, E Chiarpotto, E Albano, D Cottalasso, G Nanni, U M Marinari, A M Bassi, M U Dianzani (1985)  &lt;i&gt;Life Sci&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 36: 6 533-539&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid11</id>
<updated>2010-01-08T12:29:47Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid11'/>
<title type='html'>Induction of sister-chromatid exchanges in Chinese hamster ovary cells by the biotic ketoaldehyde methylglyoxal.</title>
<summary type='html'>The number of sister-chromatid exchanges (SCEs) per metaphase was determined in Chinese hamster ovary cells after 16 h exposure to methylglyoxal (MG) concentrations ranging from 0.1 to 0.75 mM. MG produced an increase of SCE frequency that proved to be dose-dependent, and to reach a maximum of 2 X baseline at the highest nontoxic concentration (0.5 mM).&lt;br/&gt;&lt;br/&gt;P Faggin, A M Bassi, R Finollo, G Brambilla (1985)  &lt;i&gt;Mutat Res&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 144: 3 189-191&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid12</id>
<updated>2010-01-08T12:29:47Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid12'/>
<title type='html'>Methylglyoxal-induced DNA-protein cross-links and cytotoxicity in Chinese hamster ovary cells.</title>
<summary type='html'>The technique of alkaline elution was applied to study the capacity of methylglyoxal to induce DNA damage and repair in Chinese hamster ovary cells. DNA cross-linking was observed after a 90-min exposure to a subtoxic dose (1.5 mM), and the cross-links were fully repaired by 24 h. The cross-linking appeared to be DNA-protein in nature, since proteinase treatment removed the effect. When the same c...&lt;br/&gt;&lt;br/&gt;G Brambilla, L Sciabà, P Faggin, R Finollo, A M Bassi, M Ferro, U M Marinari (1985)  &lt;i&gt;Carcinogenesis&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 6: 5 683-686&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid16</id>
<updated>2010-01-08T12:29:47Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid16'/>
<title type='html'>Further experiments on lipid peroxidation in transplanted and experimental hepatomas.</title>
<summary type='html'>The results of experiments on the subject of lipid peroxidation in hepatomas are described. It is now clear that lipid peroxidation is strongly decreased in most highly dedifferentiated hepatomas. It seems evident that the extent of the decline is strictly related to the degree of dedifferentiation. The model of diethylnitrosamine carcinogenesis, according to the method by Solt, Medline and Farber...&lt;br/&gt;&lt;br/&gt;M U Dianzani, R A Canuto, M A Rossi, G Poli, R Garcea, M E Biocca, G Cecchini, F Biasi, M Ferro, A M Bassi (1984)  &lt;i&gt;Toxicol Pathol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 12: 2 189-199&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid14</id>
<updated>2010-01-08T12:29:47Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid14'/>
<title type='html'>Induction of cytochrome(s) P450-dependent drug metabolism in cultured MH1C1 hepatoma cells.</title>
<summary type='html'>A cell line derived from a Morris hepatoma, MH1C1, was examined for its in vitro expression of monooxygenases. These cells were found to contain different forms of cytochrome P450, as shown by the response to inducers, namely phenobarbital (PB), 3-methylcholanthrene (MC) and metyrapone (MP). MH1C1 cell monolayers exposed to PB or MC showed an increase in the concentration of two spectrally distinc...&lt;br/&gt;&lt;br/&gt;M Ferro, A M Bassi, U M Marinari, G Nanni, E Chiarpotto, G Poli, M U Dianzani (1984)  &lt;i&gt;Cell Biochem Funct&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 2: 4 263-268&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid15</id>
<updated>2010-01-08T12:29:47Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid15'/>
<title type='html'>DNA-damaging activity of biotic and xenobiotic aldehydes in Chinese hamster ovary cells.</title>
<summary type='html'>Alkaline elution was employed to study DNA damage in CHO-Kl cells treated with a series of biotic and xenobiotic aldehydes. DNA cross-linking was measured in terms of the reduction in the effect of methyl methanesulphonate on the kinetics of DNA elution and was observed in cells treated with formaldehyde, acetaldehyde, methylglyoxal and malonaldehyde. Propionaldehyde, valeraldehyde, hexanal and 4-...&lt;br/&gt;&lt;br/&gt;U M Marinari, M Ferro, L Sciaba, R Finollo, A M Bassi, G Brambilla (1984)  &lt;i&gt;Cell Biochem Funct&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 2: 4 243-248&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid17</id>
<updated>2010-01-08T12:29:47Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid17'/>
<title type='html'>Study of proteins, phospholipids and cholesterol of rat bile during chronic drainage.</title>
<summary type='html'>Glycerophospholipids, cholesterol and proteins of rat bile were analyzed at different time-intervals during the bile duct cannulation over a period of 24 hr, to study a possible association between the secretion of these bile components. Glycerophospholipids and cholesterol decreased between the 16th-24th hrs, then rose again, showing a bile acid synthesis dependence. In contrast, during the entir...&lt;br/&gt;&lt;br/&gt;A Casu, D Cottalasso, M A Pronzato, A M Bassi (1981)  &lt;i&gt;Ital J Biochem&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 30: 5 388-402&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/a.m.bassi/refid18</id>
<updated>2010-01-08T12:29:47Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/a.m.bassi#refid18'/>
<title type='html'>Epidermial chalone of human skin. Review of the literature and experimental contribution (author's transl)</title>
<summary type='html'>A M Bassi, F Burlando, S Romano, M Ferro (1980)  &lt;i&gt;Pathologica&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 72: 1018 201-218&lt;br/&gt;</summary>
</entry>
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