http://publicationslist.org/data/ahmed.idbaih/atom.xml Ahmed Idbaihhttp://publicationslist.org/ahmed.idbaih$basepathfavicon.icoRecent additions to Ahmed Idbaih's PublicationsList.org pagehttp://publicationslist.org/publications.png2007-09-13T20:16:41Z http://publicationslist.org/ahmed.idbaih/refid4 2007-09-13T11:47:21Z

OBJECTIVE: To evaluate the predictive impact of chromosome 1p/19q deletions on the response and outcome of progressive low-grade gliomas (LGG) treated with up-front temozolomide (TMZ) chemotherapy. METHODS: Adult patients with measurable, progressive LGG (WHO grade II) treated with TMZ delivered at the conventional schedule (200 mg/m(2)/day for 5 consecutive days, repeated every 28 days) were retr...<br/><br/>G Kaloshi, A Benouaich-Amiel, F Diakite, S Taillibert, J Lejeune, F Laigle-Donadey, M-A Renard, W Iraqi, A Idbaih, S Paris, L Capelle, H Duffau, P Cornu, J-M Simon, K Mokhtari, M Polivka, A Omuro, A Carpentier, M Sanson, J-Y Delattre, K Hoang-Xuan (2007) <i>Neurology</i> <i></i> <i></i> 68: 21 1831-1836<br/>

http://publicationslist.org/ahmed.idbaih/refid3 2007-09-13T11:47:21Z

The Brattleboro rat is an animal model of genetically induced central diabetes insipidus. These rats show cognitive and behavioral disorders, but no neurodegenerative disease has been observed. We studied brain glucose uptake, a marker of neuronal activity, in 6 Brattleboro rats, in comparison with 6 matched Long-Evans (LE) control rats. A group of 3 Brattleboro rats and 3 Long-Evans rats was stud...<br/><br/>Ahmed Idbaih, Arlette Burlet, Homa Adle-Biassette, Raphaël Boisgard, Christine Coulon, Sophie Paris, Yannick Marie, Jean Donadieu, Khê Hoang-Xuan, Maria-Joao Ribeiro (2007) <i>Brain Res</i> <i></i> <i></i> 1158: 164-168<br/>

http://publicationslist.org/ahmed.idbaih/refid2 2007-09-13T11:47:21Z

The MDM2 SNP309 variant has been shown to increase MDM2 expression and to be associated with tumor formation. In glioblastomas, the P53/MDM2 pathway is of crucial importance and MDM2 amplification is related to poor prognosis. However, we show here that MDM2 SNP309 is not associated with glioblastoma risk, and is not a prognostic factor.<br/><br/> El Hallani, Marie, Idbaih, Rodero, Boisselier, Laigle-Donadey, Ducray, Delattre, Sanson (2007) <i>J Neurooncol</i> <i></i> <i></i> : <br/>

http://publicationslist.org/ahmed.idbaih/refid1 2007-09-13T11:47:21Z

About 5% of gliomas occur in a familial context, which suggests a genetic origin, but the predisposing molecular factors remain unknown in most cases. A series of nine familial gliomas were characterized with 1-megabase resolution BAC array-based comparative genomic hybridization (aCGH) together with germline sequence analysis of TP53. This series was compared with a literature series of familial ...<br/><br/> Idbaih, Boisselier, Sanson, Crinière, Liva, Marie, Carpentier, Paris, Laigle-Donadey, Mokhtari, Kujas, Hoang-Xuan, Delattre (2007) <i>Cancer Genet Cytogenet</i> <i></i> <i></i> 176: 2 121-126<br/>

http://publicationslist.org/ahmed.idbaih/refid5 2007-09-13T11:47:21Z

Gliomas are highly lethal neoplasms that cannot be cured by currently available therapies. Temozolomide is a recently introduced alkylating agent that has yielded a significant benefit in the treatment of high-grade gliomas. However, either de novo or acquired chemoresistance occurs frequently and has been attributed to increased levels of O6-methylguanine-DNA methyltransferase or to the loss of m...<br/><br/>Nathalie Auger, Joëlle Thillet, Krystell Wanherdrick, Ahmed Idbaih, Marie-Emmanuelle Legrier, Bernard Dutrillaux, Marc Sanson, Marie-France Poupon (2006) <i>Mol Cancer Ther</i> <i></i> <i></i> 5: 9 2182-2192<br/>

http://publicationslist.org/ahmed.idbaih/refid6 2007-09-13T11:47:21Z

CNS complications of LCH include "space occupying" lesions corresponding to histiocytic granulomas and "neurodegenerative" presentation (ND-LCH) characterized by a progressive cerebellar ataxia. Studies analyzing specifically the MRI presentation of ND-LCH are scarce. We present here the MRIs of 13 patients registered as isolated ND-LCH. Posterior fossa was involved in 12 patients (92%), showing a...<br/><br/>N Martin-Duverneuil, A Idbaih, K Hoang-Xuan, J Donadieu, T Genereau, R Guillevin, J Chiras (2006) <i>Eur Radiol</i> <i></i> <i></i> 16: 9 2074-2082<br/>

http://publicationslist.org/ahmed.idbaih/refid7 2007-09-13T11:47:21Z

BACKGROUND AND PURPOSE: In cerebral venous thrombosis (CVT), the sensitivity of conventional MRI sequences to detect clot in the sinuses or veins is incomplete and largely depends on the time elapsed since thrombus formation. Little is known concerning the corresponding diagnostic value of fluid-attenuated inversion recovery (FLAIR), echo-planar T2* susceptibility-weighted imaging (T2*SW) or diffu...<br/><br/>Ahmed Idbaih, Monique Boukobza, Isabelle Crassard, Raphaël Porcher, Marie-Germaine Bousser, Hugues Chabriat (2006) <i>Stroke</i> <i></i> <i></i> 37: 4 991-995<br/>

http://publicationslist.org/ahmed.idbaih/refid9 2007-09-13T11:47:21Z

Several molecular genetic alterations have been characterized in gliomas in the past years. Molecular profiles have been associated with specific histologic and prognostic tumor subgroups, contributing to improve the classification of gliomas. At least two alternative molecular pathways have been suggested in the astrocytoma progression involving TP53 inactivation (secondary glioblastomas) and EGF...<br/><br/>Khê Hoang-Xuan, Ahmed Idbaih, Karima Mokhtari, Marc Sanson (2005) <i>Bull Cancer</i> <i></i> <i></i> 92: 4 310-316<br/>

http://publicationslist.org/ahmed.idbaih/refid8 2007-09-13T11:47:21Z

Deletion of the short arm of chromosome 1 (1p) is considered a favorable prognostic factor in glial tumors. High-density array-comparative genomic hybridization analysis of 108 gliomas shows two distinct types of 1p deletions. Complete hemizygous losses of 1p, which are tightly associated with 19q loss and oligodendroglial phenotype, and partial 1p deletions mainly observed in astrocytic tumors an...<br/><br/>Ahmed Idbaih, Yannick Marie, Gaëlle Pierron, Caroline Brennetot, Khê Hoang-Xuan, Michèle Kujas, Karima Mokhtari, Marc Sanson, Julie Lejeune, Alain Aurias, Olivier Delattre, Jean-Yves Delattre (2005) <i>Ann Neurol</i> <i></i> <i></i> 58: 3 483-487<br/>

http://publicationslist.org/ahmed.idbaih/refid10 2007-09-13T11:47:21Z

Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma. Nevertheless, the validity of this heterogeneous pathological entity has been recurrently questioned by pathologists. Recently, analyses by comparative genomic hybridization (CGH) of a large series of MFHs suggested that MFHs consist of morphologic modulation of other poorly differentiated sarcomas like leiomyosarcomas (L...<br/><br/>Ahmed Idbaih, Jean-Michel Coindre, Josette Derré, Odette Mariani, Philippe Terrier, Dominique Ranchère, Aline Mairal, Alain Aurias (2005) <i>Lab Invest</i> <i></i> <i></i> 85: 2 176-181<br/>