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<feed xmlns="http://www.w3.org/2005/Atom" xml:lang="en"><id>http://publicationslist.org/data/andreas.steege/atom.xml</id><title>Andreas Steege's Publications List</title>
<link rel="self" type="application/atom+xml" href="http://publicationslist.org/data/andreas.steege/atom.xml"/><link rel="alternate" type="text/html" href="http://publicationslist.org/andreas.steege"/><author><name>Andreas Steege</name><uri>http://publicationslist.org/andreas.steege</uri></author><icon>$basepathfavicon.ico</icon><subtitle>Recent additions to Andreas Steege's PublicationsList.org page</subtitle><logo>http://publicationslist.org/publications.png</logo><updated>2019-09-18T18:08:48Z</updated>

<entry>
<id>http://publicationslist.org/andreas.steege/refid36</id>
<updated>2019-09-18T18:08:33Z</updated>
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<title type='html'>CCR7 Is Important for Mesangial Cell Physiology and Repair.</title>
<summary type='html'>The homeostatic chemokine receptor CCR7 serves as key molecule in lymphocyte homing into secondary lymphoid tissues. Previous experiments from our group identified CCR7 also to be expressed by human mesangial cells. Exposing cultured human mesangial cells to the receptor ligand CCL21 revealed a positive effect on these cells regarding proliferation, migration, and survival. In the present study, w...&lt;br/&gt;&lt;br/&gt;Simone Wurm, Andreas Steege, Eva-Maria Rom-Jurek, Claudia R van Roeyen, Armin Kurtz, Bernhard Banas, Miriam C Banas (2018)  &lt;i&gt;The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 66: 1 7-22&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid37</id>
<updated>2019-09-18T13:50:25Z</updated>
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<title type='html'>Role of α-adrenoceptor subtypes on corneal epithelial thickness and cell proliferation in mice.</title>
<summary type='html'>Adrenergic stimuli are important for corneal epithelial structure and healing. The purpose of the present study was to examine the hypothesis that the lack of a single α-adrenoceptor (α-AR) subtype affects corneal epithelial thickness and cell proliferation. Expression levels of α-AR mRNA were determined in mouse cornea using real-time PCR. In mice devoid of one of the three α-AR subtypes (α-...&lt;br/&gt;&lt;br/&gt;Aytan Musayeva, Caroline Manicam, Andreas Steege, Christoph Brochhausen, Beate K Straub, Katharina Bell, Norbert Pfeiffer, Adrian Gericke (2018)  &lt;i&gt;American journal of physiology. Cell physiology&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 315: 5 C757-C765&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid34</id>
<updated>2018-10-10T12:33:39Z</updated>
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<title type='html'>Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re-oxygenation in renal interlobar arteries.</title>
<summary type='html'>Hypoxia and sympathetic activation are main factors in the pathogenesis of acute kidney injury (AKI). We tested the hypothesis that noradrenaline (NE) in combination with hypoxia aggravates the vasoreactivity of renal arteries after hypoxia/re-oxygenation (H/R). We tested the role of adrenergic receptors and p38 MAPK using an in vitro H/R protocol.&lt;br/&gt;&lt;br/&gt;J Kaufmann, P Martinka, O Moede, M Sendeski, A Steege, M Fähling, M Hultström, M Gaestel, I C Moraes-Silva, T Nikitina, Z Z Liu, O Zavaritskaya, A Patzak (2015)  &lt;i&gt;Acta physiologica (Oxford, England)&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 213: 4 920-932&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid35</id>
<updated>2017-09-20T12:45:26Z</updated>
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<title type='html'>Effect of the M1 Muscarinic Acetylcholine Receptor on Retinal Neuron Number Studied with Gene-Targeted Mice.</title>
<summary type='html'>Pharmacological activation of the M1 muscarinic receptor subtype was suggested to promote the survival of retinal neurons. We examined the hypothesis that the M1 receptor is crucial for retinal neuron survival in vivo by using mice devoid of the M1 receptor gene. Muscarinic receptor gene expression was determined in the retina using real-time PCR. The amount of neurons in the retinal ganglion cell...&lt;br/&gt;&lt;br/&gt;Panagiotis Laspas, Jan J Sniatecki, Christoph Brochhausen, Andreas Steege, Evgeny Goloborodko, Marcin L Kordasz, Franz H Grus, Norbert Pfeiffer, Adrian Gericke (2015)  &lt;i&gt;Journal of molecular neuroscience : MN&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 56: 2 472-479&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid31</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Role of the M3 muscarinic acetylcholine receptor subtype in murine ophthalmic arteries after endothelial removal.</title>
<summary type='html'>We tested the hypothesis that the M3 muscarinic acetylcholine receptor subtype mediates cholinergic responses in murine ophthalmic arteries after endothelial removal.&lt;br/&gt;&lt;br/&gt;Adrian Gericke, Andreas Steege, Caroline Manicam, Tobias Böhmer, Jürgen Wess, Norbert Pfeiffer (2014)  &lt;i&gt;Investigative ophthalmology &amp; visual science&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 55: 1 625-631&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid32</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>The α₁B -adrenoceptor subtype mediates adrenergic vasoconstriction in mouse retinal arterioles with damaged endothelium.</title>
<summary type='html'>The α₁-adrenoceptor family plays a critical role in regulating ocular perfusion by mediating responses to catecholamines. The purpose of the present study was to determine the contribution of individual α₁-adrenoceptor subtypes to adrenergic vasoconstriction of retinal arterioles using gene-targeted mice deficient in one of the three adrenoceptor subtypes (α₁A-AR(-/-), α₁B-AR(-/-) and ...&lt;br/&gt;&lt;br/&gt;Tobias Böhmer, Caroline Manicam, Andreas Steege, Martin C Michel, Norbert Pfeiffer, Adrian Gericke (2014)  &lt;i&gt;British journal of pharmacology&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 171: 16 3858-3867&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid33</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Role of α₁-adrenoceptor subtypes in pupil dilation studied with gene-targeted mice.</title>
<summary type='html'>The α₁A-adrenoceptor (α₁A-AR) subtype was suggested to mediate contraction and trophic effects in the iris dilator muscle, and thus its pharmacological blockade may be involved in intraoperative floppy iris syndrome. We tested the hypothesis that the α₁A-AR mediates pupil dilation and trophic effects in the mouse iris.&lt;br/&gt;&lt;br/&gt;Marcin L Kordasz, Caroline Manicam, Andreas Steege, Evgeny Goloborodko, Claudia Amato, Panagiotis Laspas, Christoph Brochhausen, Norbert Pfeiffer, Adrian Gericke (2014)  &lt;i&gt;Investigative ophthalmology &amp; visual science&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 55: 12 8295-8301&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid29</id>
<updated>2013-02-22T13:00:20Z</updated>
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<title type='html'>Comprehensive morphometric analysis of mononuclear cell infiltration during experimental renal allograft rejection.</title>
<summary type='html'>The role of specific subtypes of infiltrating cells in acute kidney allograft rejection is still not clear and was so far not examined by different analyzing methods under standardized conditions of an experimental kidney transplantation model. Immunohistochemical staining of CD3, CD20 and CD68 was performed in rat allografts, in syngeneically transplanted rats and in control rats with a test dura...&lt;br/&gt;&lt;br/&gt;Ute Hoffmann, Tobias Bergler, Bettina Jung, Andreas Steege, Claudia Pace, Petra Rümmele, Stephan Reinhold, Bernd Krüger, Bernhard K Krämer, Bernhard Banas (2013)  &lt;i&gt;Transpl Immunol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 28: 1 24-31&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid30</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Contribution of nitric oxide synthase isoforms to cholinergic vasodilation in murine retinal arterioles.</title>
<summary type='html'>Nitric oxide synthases (NOSs) are critically involved in regulation of ocular perfusion. However, the contribution of the individual NOS isoforms to vascular responses is unknown in the retina. Because some previous findings suggested an involvement of inducible nitric oxide synthase (iNOS) in the regulation of retinal vascular tone, a major goal of the present study was to examine the hypothesis ...&lt;br/&gt;&lt;br/&gt;Adrian Gericke, Evgeny Goloborodko, Jan J Sniatecki, Andreas Steege, Leszek Wojnowski, Norbert Pfeiffer (2013)  &lt;i&gt;Experimental eye research&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 109:  60-66&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid27</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Multilevel regulation of HIF-1 signaling by TTP.</title>
<summary type='html'>Hypoxia-inducible factor-1 (HIF-1) is a well-studied transcription factor mediating cellular adaptation to hypoxia. It also plays a crucial role under normoxic conditions, such as in inflammation, where its regulation is less well understood. The 3'-untranslated region (UTR) of HIF-1α mRNA is among the most conserved UTRs in the genome, hinting toward posttranscriptional regulation. To identify p...&lt;br/&gt;&lt;br/&gt;Michael Fähling, Anja Bondke Persson, Bertram Klinger, Edgar Benko, Andreas Steege, Mumtaz Kasim, Andreas Patzak, Pontus B Persson, Gunter Wolf, Nils Blüthgen, Ralf Mrowka (2012)  &lt;i&gt;Molecular biology of the cell&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 23: 20 4129-4141&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid25</id>
<updated>2012-08-09T13:31:05Z</updated>
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<title type='html'>Bronchoepithelial expression of CXCR1 and CXCR2 does not facilitate transepithelial migration of neutrophils.</title>
<summary type='html'>Background: Neutrophilic airway inflammation is one of the key features of chronic obstructive pulmonary disease (COPD). The chemokine receptors 1 (CXCR1) and 2 (CXCR2) are expressed in the bronchial mucosa during chronic inflammation and might be of importance for transepithelial migration of neutrophils. Objectives: This study addressed the role of bronchoepithelial CXCR1 and CXCR2 expression wi...&lt;br/&gt;&lt;br/&gt;Christian Schulz, Benjamin Stoelcker, Brigitte Ruhland, Nico Jentsch, Andreas Steege (2012)  &lt;i&gt;Respiration&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 84: 2 108-116&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid26</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Expression of fourteen novel obesity-related genes in Zucker diabetic fatty rats.</title>
<summary type='html'>Genome-wide association studies (GWAS) are useful to reveal an association between single nucleotide polymorphisms and different measures of obesity. A multitude of new loci has recently been reported, but the exact function of most of the according genes is not known. The aim of our study was to start elucidating the function of some of these genes.&lt;br/&gt;&lt;br/&gt;Peter M Schmid, Iris Heid, Christa Buechler, Andreas Steege, Markus Resch, Christoph Birner, Dierk H Endemann, Guenter A Riegger, Andreas Luchner (2012)  &lt;i&gt;Cardiovascular diabetology&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 11:  &lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid20</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice.</title>
<summary type='html'>Endothelin 1 contributes to renal blood flow control and pathogenesis of kidney diseases. The differential effects, however, of endothelin 1 (ET-1) on afferent (AA) and efferent arterioles (EA) remain to be established.&lt;br/&gt;&lt;br/&gt;Janice Schildroth, Juliane Rettig-Zimmermann, Philipp Kalk, Andreas Steege, Michael Fähling, Mauricio Sendeski, Alexander Paliege, En Yin Lai, Sebastian Bachmann, Pontus B Persson, Berthold Hocher, Andreas Patzak (2011)  &lt;i&gt;Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 26: 3 779-789&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid22</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Globular and full-length adiponectin induce NO-dependent vasodilation in resistance arteries of Zucker lean but not Zucker diabetic fatty rats.</title>
<summary type='html'>Adiponectin increases nitric oxide (NO) production in endothelial cell cultures and is reduced in the circulation of obese and diabetic patients, but its functional effect on resistance arteries is not yet studied in detail.&lt;br/&gt;&lt;br/&gt;Peter M Schmid, Markus Resch, Andreas Steege, Sabine Fredersdorf-Hahn, Benjamin Stoelcker, Christoph Birner, Christian Schach, Christa Buechler, Guenter A J Riegger, Andreas Luchner, Dierk H Endemann (2011)  &lt;i&gt;American journal of hypertension&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 24: 3 270-277&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid24</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Identification of the muscarinic acetylcholine receptor subtype mediating cholinergic vasodilation in murine retinal arterioles.</title>
<summary type='html'>To identify the muscarinic acetylcholine receptor subtype that mediates cholinergic vasodilation in murine retinal arterioles.&lt;br/&gt;&lt;br/&gt;Adrian Gericke, Jan J Sniatecki, Evgeny Goloborodko, Andreas Steege, Olga Zavaritskaya, Jan M Vetter, Franz H Grus, Andreas Patzak, Jürgen Wess, Norbert Pfeiffer (2011)  &lt;i&gt;Investigative ophthalmology &amp; visual science&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 52: 10 7479-7484&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid23</id>
<updated>2017-09-20T12:53:35Z</updated>
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<title type='html'>Functional role of α1-adrenoceptor subtypes in murine ophthalmic arteries.</title>
<summary type='html'>To identify the α(1)-adrenoceptor (α(1)-AR) subtypes mediating vascular adrenergic responses in murine ophthalmic arteries.&lt;br/&gt;&lt;br/&gt;Adrian Gericke, Marcin L Kordasz, Andreas Steege, Atsushi Sanbe, Evgeny Goloborodko, Jan M Vetter, Andreas Patzak, Norbert Pfeiffer (2011)  &lt;i&gt;Investigative ophthalmology &amp; visual science&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 52: 7 4795-4799&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid19</id>
<updated>2012-08-09T13:31:05Z</updated>
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<title type='html'>PU.1 is regulated by NF-kappaB through a novel binding site in a 17 kb upstream enhancer element.</title>
<summary type='html'>The majority of patients with acute myeloid leukemia (AML) still die of their disease, and novel therapeutic concepts are needed. Timely expression of the hematopoietic master regulator PU.1 is crucial for normal development of myeloid and lymphoid cells. Targeted disruption of an upstream regulatory element (URE) located several kb upstream in the PU.1 promoter decreases PU.1 expression thereby i...&lt;br/&gt;&lt;br/&gt;N Bonadies, Ch Neururer, A Steege, S Vallabhapurapu, T Pabst, B U Mueller (2010)  &lt;i&gt;Oncogene&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 29: 7 1062-1072&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid21</id>
<updated>2012-08-09T13:31:05Z</updated>
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<title type='html'>Superoxide dismutase 1 limits renal microvascular remodeling and attenuates arteriole and blood pressure responses to angiotensin II via modulation of nitric oxide bioavailability.</title>
<summary type='html'>Oxidative stress is associated with vascular remodeling and increased preglomerular resistance that are both implicated in the pathogenesis of renal and cardiovascular disease. Angiotensin II induces superoxide production, which is metabolized by superoxide dismutase (SOD) or scavenged by NO. We investigated the hypothesis that SOD1 regulates renal microvascular remodeling, blood pressure, and art...&lt;br/&gt;&lt;br/&gt;Mattias Carlström, En Yin Lai, Zufu Ma, Andreas Steege, Andreas Patzak, Ulf J Eriksson, Jon O Lundberg, Christopher S Wilcox, A Erik G Persson (2010)  &lt;i&gt;Hypertension&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 56: 5 907-913&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid18</id>
<updated>2012-08-09T13:31:05Z</updated>
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<title type='html'>Cholinergic responses of ophthalmic arteries in M3 and M5 muscarinic acetylcholine receptor knockout mice.</title>
<summary type='html'>To determine the functional role of M(3) and M(5) muscarinic acetylcholine receptor subtypes in ophthalmic arteries using gene-targeted mice.&lt;br/&gt;&lt;br/&gt;Adrian Gericke, Veronique G A Mayer, Andreas Steege, Andreas Patzak, Ulrike Neumann, Franz H Grus, Stephanie C Joachim, Lars Choritz, Jürgen Wess, Norbert Pfeiffer (2009)  &lt;i&gt;Invest Ophthalmol Vis Sci&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 50: 10 4822-4827&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid17</id>
<updated>2012-08-09T13:31:05Z</updated>
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<title type='html'>Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation protein.</title>
<summary type='html'>Fragile X syndrome is a common inherited cause of mental retardation that results from loss or mutation of the fragile X mental retardation protein (FMRP). In this study, we identified the mRNA of the basic helix-loop-helix transcription factor human achaete-scute homologue-1 (hASH1 or ASCL1), which is required for normal development of the nervous system and has been implicated in the formation o...&lt;br/&gt;&lt;br/&gt;Michael Fähling, Ralf Mrowka, Andreas Steege, Karin M Kirschner, Edgar Benko, Benjamin Förstera, Pontus B Persson, Bernd J Thiele, Jochen C Meier, Holger Scholz (2009)  &lt;i&gt;J Biol Chem&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 284: 7 4255-4266&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid12</id>
<updated>2012-08-09T13:31:05Z</updated>
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<title type='html'>Angiotensin II response in afferent arterioles of mice lacking either the endothelial or neuronal isoform of nitric oxide synthase.</title>
<summary type='html'>The aim of the study is to evaluate the impact of nitric oxide (NO) produced by endothelial NO synthase (eNOS) and neuronal NOS (nNOS) on the angiotensin II response in afferent arterioles (Af). Dose responses were assessed for angiotensin II in microperfused Af of mice homozygous for disruption of the eNOS gene [eNOS(-/-)], or nNOS gene [nNOS(-/-)], and their wild-type controls, eNOS(+/+) and nNO...&lt;br/&gt;&lt;br/&gt;Andreas Patzak, Andreas Steege, En Yin Lai, Jan Ole Brinkmann, Eckehardt Kupsch, Nadine Spielmann, Adrian Gericke, Angela Skalweit, Johannes Stegbauer, Pontus B Persson, Erdmann Seeliger (2008)  &lt;i&gt;Am J Physiol Regul Integr Comp Physiol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 294: 2 R429-R437&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid13</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid13'/>
<title type='html'>Endothelial nitric oxide synthase is predominantly involved in angiotensin II modulation of renal vascular resistance and norepinephrine release.</title>
<summary type='html'>Nitric oxide (NO) is mainly generated by endothelial NO synthase (eNOS) or neuronal NOS (nNOS). Recent studies indicate that angiotensin II generates NO release, which modulates renal vascular resistance and sympathetic neurotransmission. Experiments in wild-type [eNOS(+/+) and nNOS(+/+)], eNOS-deficient [eNOS(-/-)], and nNOS-deficient [nNOS(-/-)] mice were performed to determine which NOS isoform...&lt;br/&gt;&lt;br/&gt;Johannes Stegbauer, Yvonne Kuczka, Oliver Vonend, Ivo Quack, Lorenz Sellin, Andreas Patzak, Andreas Steege, Kristina Langnaese, Lars Christian Rump (2008)  &lt;i&gt;Am J Physiol Regul Integr Comp Physiol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 294: 2 R421-R428&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid15</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid15'/>
<title type='html'>Wilms' tumor protein (-KTS) modulates renin gene transcription.</title>
<summary type='html'>Renin plays a crucial role in the control of various physiological processes such as blood pressure and body fluid homeostasis. Here, we show that a splice variant of the Wilms' tumor protein lacking three amino acids WT1(-KTS) suppresses renin gene transcription. Using bioinformatics tools, we initially predicted that a WT1-binding site exists in a regulatory region about 12 kb upstream of the re...&lt;br/&gt;&lt;br/&gt;Andreas Steege, Michael Fähling, Alexander Paliege, Anja Bondke, Karin M Kirschner, Peter Martinka, Charlotte Kaps, Andreas Patzak, Pontus B Persson, Bernd J Thiele, Holger Scholz, Ralf Mrowka (2008)  &lt;i&gt;Kidney Int&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 74: 4 458-466&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid14</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid14'/>
<title type='html'>Nitric oxide deficiency and increased adenosine response of afferent arterioles in hydronephrotic mice with hypertension.</title>
<summary type='html'>Afferent arterioles were used to investigate the role of adenosine, angiotensin II, NO, and reactive oxygen species in the pathogenesis of increased tubuloglomerular feedback response in hydronephrosis. Hydronephrosis was induced in wild-type mice, superoxide dismutase-1 overexpressed mice (superoxide-dismutase-1 transgenic), and deficient mice (superoxide dismutase-1 knockout). Isotonic contracti...&lt;br/&gt;&lt;br/&gt;Mattias Carlström, En Yin Lai, Andreas Steege, Mauricio Sendeski, Zufu Ma, Sheller Zabihi, Ulf J Eriksson, Andreas Patzak, A Erik G Persson (2008)  &lt;i&gt;Hypertension&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 51: 5 1386-1392&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid16</id>
<updated>2012-08-09T13:31:05Z</updated>
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<title type='html'>A high-throughput reporter gene assay to prove the ability of natural compounds to modulate glutathione peroxidase, superoxide dismutase and catalase gene promoters in V79 cells.</title>
<summary type='html'>The aim of the study was to establish a 96-well microtiter plate-based reporter gene assay to test the influence of natural compounds on the promoter activities of rat catalase, human glutathione peroxidase and human superoxide dismutase expressed in V79 cells. Luciferase expression vectors with the promoter regions of the genes coding for the three above-mentioned enzymes were constructed and tra...&lt;br/&gt;&lt;br/&gt;Kristina Ullmann, Anne Maria Wiencierz, Carsten Müller, Rene Thierbach, Andreas Steege, Shinya Toyokuni, Pablo Steinberg (2008)  &lt;i&gt;Free Radic Res&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 42: 8 746-753&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid3</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid3'/>
<title type='html'>Dissecting the action of an evolutionary conserved non-coding region on renin promoter activity.</title>
<summary type='html'>Elucidating the mechanisms of the human transcriptional regulatory network is a major challenge of the post-genomic era. One important aspect is the identification and functional analysis of regulatory elements in non-coding DNA. Genomic sequence comparisons between related species can guide the discovery of cis-regulatory sequences. Using this technique, we identify a conserved region CNSmd of ap...&lt;br/&gt;&lt;br/&gt;Ralf Mrowka, Andreas Steege, Charlotte Kaps, Hanspeter Herzel, Bernd J Thiele, Pontus B Persson, Nils Blüthgen (2007)  &lt;i&gt;Nucleic Acids Res&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 35: 15 5120-5129&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid2</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid2'/>
<title type='html'>eNOS involved in colitis-induced mucosal blood flow increase.</title>
<summary type='html'>The role of NO in inflammatory bowel disease is controversial. Studies indicate that endothelial nitric oxide synthase (eNOS) might be involved in protecting the mucosa against colonic inflammation. The aim of this study was to investigate the involvement of nitric oxide (NO) in regulating colonic mucosal blood flow in two different colitis models in rats. In anesthetized control and colitic rats,...&lt;br/&gt;&lt;br/&gt;Joel Petersson, Olof Schreiber, Andreas Steege, Andreas Patzak, Anna Hellsten, Mia Phillipson, Lena Holm (2007)  &lt;i&gt;Am J Physiol Gastrointest Liver Physiol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 293: 6 G1281-G1287&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid4</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid4'/>
<title type='html'>Adenosine restores angiotensin II-induced contractions by receptor-independent enhancement of calcium sensitivity in renal arterioles.</title>
<summary type='html'>Adenosine is coupled to energy metabolism and regulates tissue blood flow by modulating vascular resistance. In this study, we investigated isolated, perfused afferent arterioles of mice, which were subjected to desensitization during repeated applications of angiotensin II. Exogenously applied adenosine restores angiotensin II-induced contractions by increasing calcium sensitivity of the arteriol...&lt;br/&gt;&lt;br/&gt;En Yin Lai, Peter Martinka, Michael Fähling, Ralf Mrowka, Andreas Steege, Adrian Gericke, Mauricio Sendeski, P B Persson, A Erik G Persson, Andreas Patzak (2006)  &lt;i&gt;Circ Res&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 99: 10 1117-1124&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid5</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid5'/>
<title type='html'>Translational control of collagen prolyl 4-hydroxylase-alpha(I) gene expression under hypoxia.</title>
<summary type='html'>Hypoxia is a pro-fibrotic stimulus, which is associated with enhanced collagen synthesis, as well as with augmented collagen prolyl 4-hydroxylase (C-P4H) activity. C-P4H activity is controlled mainly by regulated expression of the alpha C-P4H subunit. In this study we demonstrate that the increased synthesis of C-P4H-alpha(I) protein in human HT1080 fibroblasts under long term hypoxia (36 h, 1% ox...&lt;br/&gt;&lt;br/&gt;Michael Fähling, Ralf Mrowka, Andreas Steege, Grit Nebrich, Andrea Perlewitz, Pontus B Persson, Bernd J Thiele (2006)  &lt;i&gt;J Biol Chem&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 281: 36 26089-26101&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid6</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid6'/>
<title type='html'>Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.</title>
<summary type='html'>Adenosine (Ado) mediates vasoconstriction via A(1)-Ado receptors and vasodilation via A(2)-Ado receptors in the kidney. It interacts with angiotensin II (Ang II), which is important for renal hemodynamics and tubuloglomerular feedback (TGF). The aim was to investigate the function of Ado receptors in the Ado-Ang II interaction in mouse microperfused, afferent arterioles. Ado (10(-11)-10(-4) mol/l)...&lt;br/&gt;&lt;br/&gt;E Y Lai, A Patzak, A Steege, R Mrowka, R Brown, N Spielmann, P B Persson, B B Fredholm, A E G Persson (2006)  &lt;i&gt;Kidney Int&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 70: 4 690-698&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid8</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid8'/>
<title type='html'>Influence of the adenosine A1 receptor on blood pressure regulation and renin release.</title>
<summary type='html'>The present study was performed to investigate the role of adenosine A1 receptors in regulating blood pressure in conscious mice. Adenosine A1-receptor knockout (A1R-/-) mice and their wild-type (A1R+/+) littermates were placed on standardized normal-salt (NS), high-salt (HS), or salt-deficient (SD) diets for a minimum of 10 days before telemetric blood pressure and urinary excretion measurements ...&lt;br/&gt;&lt;br/&gt;Russell D Brown, Peter Thorén, Andreas Steege, Ralf Mrowka, Johan Sällström, Ole Skøtt, Bertil B Fredholm, A Erik G Persson (2006)  &lt;i&gt;Am J Physiol Regul Integr Comp Physiol&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 290: 5 R1324-R1329&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid7</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid7'/>
<title type='html'>Heterogeneous nuclear ribonucleoprotein-A2/B1 modulate collagen prolyl 4-hydroxylase, alpha (I) mRNA stability.</title>
<summary type='html'>Collagen prolyl 4-hydroxylase (C-P4H) alpha-subunit is of regulatory importance in the assembling of C-P4H tetramers, which are necessary for the hydroxylation of procollagen chains. Change in collagen expression by hypoxia or iron diminishment is a significant issue in extracellular matrix remodeling. It was proposed that C-P4H-alpha (I) is regulated at the posttrancriptional level under these co...&lt;br/&gt;&lt;br/&gt;Michael Fähling, Ralf Mrowka, Andreas Steege, Peter Martinka, Pontus B Persson, Bernd J Thiele (2006)  &lt;i&gt;J Biol Chem&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 281: 14 9279-9286&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid10</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid10'/>
<title type='html'>Role of nucleolin in posttranscriptional control of MMP-9 expression.</title>
<summary type='html'>Matrix-metalloproteinases (MMPs), which are able to degrade extra cellular matrix (ECM) components, are crucial in ECM-remodeling, under physiological (e.g., embryogenesis, wound healing, angiogenesis) or pathophysiological conditions (e.g., arthritis, cancer progression and metastasis, fibrosis). Treating HT1080 cells, a human fibrosarcoma cell line, with the iron chelator 2,2-Dipyridyl, which mi...&lt;br/&gt;&lt;br/&gt;Michael Fähling, Andreas Steege, Andrea Perlewitz, Benno Nafz, Ralf Mrowka, Pontus B Persson, Bernd J Thiele (2005)  &lt;i&gt;Biochim Biophys Acta&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 1731: 1 32-40&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid9</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid9'/>
<title type='html'>Angiotensin II sensitivity of afferent glomerular arterioles in endothelin-1 transgenic mice.</title>
<summary type='html'>Although endothelin I (ET-1) is a very potent vasoconstrictor, ET-1 transgenic (ET-1 tg) mice are not hypertensive. This might be due to higher bioavailability of nitric oxide (NO) in ET-1 tg, which counteracts the effect of vasoconstrictors. We hypothesized lower angiotensin II (Ang II) sensitivity of afferent arterioles in ET-1 tg.&lt;br/&gt;&lt;br/&gt;Andreas Patzak, Julia Bontscho, Enyin Lai, Eckehardt Kupsch, Angela Skalweit, Claus-Michael Richter, Mathias Zimmermann, Christa Thöne-Reineke, Olaf Joehren, Michael Godes, Andreas Steege, Berthold Hocher (2005)  &lt;i&gt;Nephrol Dial Transplant&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 20: 12 2681-2689&lt;br/&gt;</summary>
</entry>
<entry>
<id>http://publicationslist.org/andreas.steege/refid11</id>
<updated>2012-08-09T13:31:05Z</updated>
<link rel='alternate' type='text/html' href='http://publicationslist.org/andreas.steege#refid11'/>
<title type='html'>AT1 receptors mediate angiotensin II-induced release of nitric oxide in afferent arterioles.</title>
<summary type='html'>Recent studies have indicated that angiotensin II (Ang II) possibly activates the nitric oxide (NO) system. We investigated the role of AT receptor subtypes (AT-R) in mediating the Ang II-induced NO release in afferent arterioles (Af) of mice.&lt;br/&gt;&lt;br/&gt;Andreas Patzak, En Y Lai, Ralf Mrowka, Andreas Steege, Pontus B Persson, A Erik G Persson (2004)  &lt;i&gt;Kidney Int&lt;/i&gt; &lt;i&gt;&lt;/i&gt; &lt;i&gt;&lt;/i&gt; 66: 5 1949-1958&lt;br/&gt;</summary>
</entry>
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