http://publicationslist.org/data/andrew.day/atom.xml Andrew Dayhttp://publicationslist.org/andrew.day$basepathfavicon.icoRecent additions to Andrew Day's PublicationsList.org pagehttp://publicationslist.org/publications.png2010-08-09T10:13:00Z http://publicationslist.org/andrew.day/refid11 2010-08-09T10:12:38Z

AIMS: The main aim of this study was to assess the nutritional status of children with newly diagnosed Coeliac disease (CD)with comparison to matched controls. A further aim was to assess relationships between presentation patterns and nutrition in childhood CD. METHODS: The nutritional status of newly diagnosed CD was assessed by anthropometry, Bioelectrical Impedance and serum leptin levels, and...<br/><br/>B Aurangzeb, S T Leach, D A Lemberg, A S Day (2010) <i>Acta Paediatr</i> <i></i> <i></i> 99: 7 1020-1025<br/>

http://publicationslist.org/andrew.day/refid10 2010-08-09T10:12:38Z

BACKGROUND & AIMS: In a prospective study of children with severe ulcerative colitis (UC), we aimed to assess outcomes and to identify predictors of nonresponse to intravenous corticosteroids. METHODS: A total of 128 children (47% males; 12.9 +/- 3.9 y) hospitalized for severe UC were enrolled from 10 pediatric centers. Clinical and laboratory data and the Pediatric UC Activity Index (PUCAI) were ...<br/><br/>Dan Turner, David Mack, Neal Leleiko, Thomas D Walters, Krista Uusoue, Steven T Leach, Andrew S Day, Wallace Crandall, Mark S Silverberg, James Markowitz, Anthony R Otley, David Keljo, Petar Mamula, Subra Kugathasan, Jeffrey Hyams, Anne M Griffiths (2010) <i>Gastroenterology</i> <i></i> <i></i> 138: 7 2282-2291<br/>

http://publicationslist.org/andrew.day/refid12 2010-08-09T10:12:38Z

A S Day, R B Gearry (2010) <i>Dig Dis Sci</i> <i></i> <i></i> 55: 4 877-879<br/>

http://publicationslist.org/andrew.day/refid13 2010-08-09T10:12:38Z

BACKGROUND: Poor bone acquisition and increased fracture risk are significant complications associated with Crohn's disease (CD). The aim of this study was to determine the effects of 8 weeks of exclusive enteral nutrition (EEN) therapy upon markers of bone turnover in children with newly diagnosed CD. METHODS: Twenty-three children with newly diagnosed CD and 20 controls (without CD) were enrolle...<br/><br/>Kylie E Whitten, Steven T Leach, Timothy D Bohane, Helen J Woodhead, Andrew S Day (2010) <i>J Gastroenterol</i> <i></i> <i></i> 45: 4 399-405<br/>

http://publicationslist.org/andrew.day/refid15 2010-08-09T10:12:38Z

BACKGROUND AND AIMS: Various markers are used to monitor disease activity in paediatric Crohn's disease (CD). We sought to determine whether C-reactive protein measurement was useful in the assessment of disease activity in children with CD, with comparison to the other markers of disease activity. METHODS: Details of disease activity, C-reactive protein and inflammatory markers were obtained retr...<br/><br/>Samantha Tilakaratne, Daniel A Lemberg, Steven T Leach, Andrew S Day (2010) <i>Dig Dis Sci</i> <i></i> <i></i> 55: 1 131-136<br/>

http://publicationslist.org/andrew.day/refid14 2010-08-09T10:12:38Z

BACKGROUND: Campylobacter concisus and other members of the Campylobacter genus have recently been suggested as possible etiological agents of Crohn's disease (CD). To further investigate this issue we determined the prevalence of these organisms in pediatric patients newly diagnosed with CD. METHODS: DNA was extracted from fecal specimens collected from 54 children with CD, 27 noninflammatory bow...<br/><br/>Si Ming Man, Li Zhang, Andrew S Day, Steven T Leach, Daniel A Lemberg, Hazel Mitchell (2010) <i>Inflamm Bowel Dis</i> <i></i> <i></i> 16: 6 1008-1016<br/>

http://publicationslist.org/andrew.day/refid8 2010-08-09T10:12:38Z

In this article, we examine the current and increasing emphasis on accountability and patient safety in health care, focusing on practices of incident reporting and management in New South Wales, Australia. We describe the frames of accountability associated with an incident reporting system, and explore how this system manifests in practice. In contrast to literature that situates incident report...<br/><br/>Su-yin Hor, Rick Iedema, Katrina Williams, Les White, Peter Kennedy, Andrew S Day (2010) <i>Qual Health Res</i> <i></i> <i></i> 20: 8 1091-1100<br/>

http://publicationslist.org/andrew.day/refid9 2010-08-09T10:12:38Z

Nitin Gupta, Andrew S Day (2010) <i>J Paediatr Child Health</i> <i></i> <i></i> 46: 1-2 67-68<br/>

http://publicationslist.org/andrew.day/refid7 2010-08-09T10:12:38Z

The Pediatric Crohn Disease Activity Index (PCDAI) is an established and validated measure of disease activity in children with Crohn disease. However, its use in the research setting can be limited because of ambiguity of the subjective and anthropometric components of the index. Here we propose and evaluate a modified PCDAI (Mod PCDAI) consisting of the laboratory measures of the PCDAI plus C-re...<br/><br/>Steven T Leach, Lily Nahidi, Samantha Tilakaratne, Andrew S Day, Daniel A Lemberg (2010) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 51: 2 232-236<br/>

http://publicationslist.org/andrew.day/refid2 2010-08-09T10:12:38Z

Michael Schultz, Richard Gearry, Russell Walmsley, Andrew S Day, Alan Fraser, John Wyeth, Murray Barclay, Geoff Clover, Cathryn Whiteside (2010) <i>N Z Med J</i> <i></i> <i></i> 123: 1314 134-144<br/>

http://publicationslist.org/andrew.day/refid1 2010-08-09T10:12:38Z

Crohn's disease and ulcerative colitis are lifelong conditions with particular effects upon nutrition, especially in children and adolescents. Various therapies are available for these conditions but there remains no cure. Over the last decades, exclusive enteral nutrition (EEN) has been demonstrated to have efficacy in the induction of remission, along with numerous other nutritional and inflamma...<br/><br/>Anthony R Otley, Richard K Russell, Andew S Day (2010) <i>Expert Rev Clin Immunol</i> <i></i> <i></i> 6: 4 667-676<br/>

http://publicationslist.org/andrew.day/refid4 2010-08-09T10:12:38Z

The presence of Campylobacter concisus in the saliva of healthy individuals and patients with inflammatory bowel disease (IBD) was examined. C. concisus was detected in 97% of the healthy individuals and 100% of the patients with IBD tested. The C. concisus culture positivity rate in younger children was significantly lower than that in the other age groups.<br/><br/>Li Zhang, Vanna Budiman, Andrew S Day, Hazel Mitchell, Daniel A Lemberg, Stephen M Riordan, Michael Grimm, Steven T Leach, Yazan Ismail (2010) <i>J Clin Microbiol</i> <i></i> <i></i> 48: 8 2965-2967<br/>

http://publicationslist.org/andrew.day/refid3 2010-08-09T10:12:38Z

Suzan Wong, Daniel A Lemberg, Andrew S Day (2010) <i>J Dig Dis</i> <i></i> <i></i> 11: 3 185-188<br/>

http://publicationslist.org/andrew.day/refid5 2010-08-09T10:12:38Z

BACKGROUND AND AIM: Infliximab (IFX) is a monoclonal antibody licensed to treat medically refractory Crohn's disease (CD). Our aim was to elucidate the effects of IFX therapy on clinical, growth and serum parameters in children with CD in a single pediatric center in Sydney, Australia. METHODS: A retrospective case series review of children treated with IFX for CD at Sydney Children's Hospital, Au...<br/><br/>Daniel M Sinitsky, Daniel A Lemberg, Steven T Leach, Timothy D Bohane, Reuben Jackson, Andrew S Day (2010) <i>J Gastroenterol Hepatol</i> <i></i> <i></i> 25: 4 810-816<br/>

http://publicationslist.org/andrew.day/refid6 2010-08-09T10:12:38Z

Richard B Gearry, Andrew S Day, Murray L Barclay, Rupert W L Leong, Miles P Sparrow (2010) <i>J Gastroenterol Hepatol</i> <i></i> <i></i> 25: 4 653-655<br/>

http://publicationslist.org/andrew.day/refid22 2010-08-09T10:12:38Z

Chee Y Ooi, Anthony V Dilley, Andrew S Day (2009) <i>Pediatr Int</i> <i></i> <i></i> 51: 1 156-158<br/>

http://publicationslist.org/andrew.day/refid23 2010-08-09T10:12:38Z

Defensins are antimicrobial peptides produced at a variety of epithelial surfaces. In the intestinal tract, they contribute to host immunity and assist in maintaining the balance between protection from pathogens and tolerance to normal flora. However, attenuated expression of defensins compromises host immunity and hence may alter the balance toward inflammation. Altered defensin production is su...<br/><br/>Malith Ramasundara, Steven T Leach, Daniel A Lemberg, Andrew S Day (2009) <i>J Gastroenterol Hepatol</i> <i></i> <i></i> 24: 2 202-208<br/>

http://publicationslist.org/andrew.day/refid21 2010-08-09T10:12:38Z

Approximately 25 % of individuals with Crohn's disease (CD), a life-long relapsing-remitting disease, are diagnosed during childhood and adolescence. Symptoms of CD, including abdominal pain, nausea and diarrhoea, can lead to reduced food intake, which may negatively have an impact on nutritional status during this critical period of growth and development. The aims of the present study were to as...<br/><br/>Rachel Pons, Kylie E Whitten, Helen Woodhead, Steven T Leach, Daniel A Lemberg, Andrew S Day (2009) <i>Br J Nutr</i> <i></i> <i></i> 102: 7 1052-1057<br/>

http://publicationslist.org/andrew.day/refid25 2010-08-09T10:12:38Z

The presence of Campylobacter species other than Campylobacter jejuni and antibodies to Campylobacter concisus in children were investigated. A significantly greater presence of C. concisus and higher levels of antibodies to C. concisus were detected in children with Crohn's disease (CD) than in controls. Campylobacter species other than C. jejuni were isolated from intestinal biopsy specimens of ...<br/><br/>Li Zhang, Si Ming Man, Andrew S Day, Steven T Leach, Daniel A Lemberg, Shoma Dutt, Michael Stormon, Anthony Otley, Edward V O'Loughlin, Annabel Magoffin, Patrick H Y Ng, Hazel Mitchell (2009) <i>J Clin Microbiol</i> <i></i> <i></i> 47: 2 453-455<br/>

http://publicationslist.org/andrew.day/refid20 2010-08-09T10:12:38Z

Mario Guslandi, Li Zhang, Si Ming Man, Andrew S Day, Steven T Leach, Daniel A Lemberg, Shoma Dutt, Michael Stormon, Anthony Otley, Edward V O'Loughlin, Annabel Magoffin, Patrick H Y Ng, Hazel Mitchell (2009) <i>J Clin Microbiol</i> <i></i> <i></i> 47: 5 1614-1615<br/>

http://publicationslist.org/andrew.day/refid17 2010-08-09T10:12:38Z

OBJECTIVES: Variation in medical care can be a barrier to improving clinical outcomes. We aim to describe the variation in care of Crohn disease as provided by a broad sample of pediatric gastroenterologists. METHODS: Two hundred forty-six Crohn disease patients of 93 pediatric gastroenterologists from 48 practice sites starting treatment with either thiopurine or infliximab were studied. We asses...<br/><br/>Richard B Colletti, Robert N Baldassano, David E Milov, Peter A Margolis, Athos Bousvaros, Wallace V Crandall, Karen D Crissinger, Michael A D'Amico, Andrew S Day, Lee A Denson, Marla Dubinsky, Dawn R Ebach, Edward J Hoffenberg, Howard A Kader, David J Keljo, Ian H Leibowitz, Petar Mamula, Marian D Pfefferkorn, M Azim Qureshi (2009) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 49: 3 297-303<br/>

http://publicationslist.org/andrew.day/refid18 2010-08-09T10:12:38Z

OBJECTIVE: To characterise epidemiological, clinical and laboratory features of children in New South Wales with chronic hepatitis B (HBV) or C (HCV) infections. DESIGN AND SETTING: Retrospective record review of epidemiological, clinical, laboratory, liver biopsy and treatment data for children (aged < 18 years) referred to tertiary referral paediatric and refugee clinics in NSW with chronic HBV ...<br/><br/>Scott Nightingale, Michael O Stormon, Andrew S Day, Murray T Webber, Kate A Ward, Edward V O'Loughlin (2009) <i>Med J Aust</i> <i></i> <i></i> 190: 12 670-673<br/>

http://publicationslist.org/andrew.day/refid16 2010-08-09T10:12:38Z

Cow's milk protein allergy is a condition commonly managed by general practitioners and paediatricians. The diagnosis is usually made in the first 12 months of life. Management of immediate allergic reactions and anaphylaxis includes the prevention of accidental food ingestion and provision of an adrenaline autoinjector, if appropriate. By contrast, the clinical course of delayed food-allergic man...<br/><br/>Katrina J Allen, Geoffrey P Davidson, Andrew S Day, David J Hill, Andrew S Kemp, Jane E Peake, Susan L Prescott, Albert Shugg, John K H Sinn, Ralf G Heine (2009) <i>J Paediatr Child Health</i> <i></i> <i></i> 45: 9 481-486<br/>

http://publicationslist.org/andrew.day/refid19 2010-08-09T10:12:38Z

Aim: Although available data support a role for exclusive enteral nutrition (EEN) in children with Crohn's disease (CD), use of this therapy varies. The aim of this study was to define the patterns of use of EEN across Australia and to better understand the reasons for this variation. Methods: Using an existing email network, Australian paediatric gastroenterologists were asked to provide details ...<br/><br/>Andrew S Day, Tracey Stephenson, Michael Stewart, Anthony R Otley (2009) <i>J Paediatr Child Health</i> <i></i> <i></i> : <br/>

http://publicationslist.org/andrew.day/refid33 2010-08-09T10:12:39Z

Three types of infant formula (soy, extensively hydrolysed and amino acid) may be appropriate for treating cows milk protein allergy. Selection of a formula depends on the allergy syndrome to be treated. Extensively hydrolysed formula is recommended as first choice for infants under 6 months of age for treating immediate cows milk allergy (non-anaphylactic), food protein-induced enterocolitis synd...<br/><br/>Andrew S Kemp, David J Hill, Katrina J Allen, Kym Anderson, Geoffrey P Davidson, Andrew S Day, Ralph G Heine, Jane E Peake, Susan L Prescott, Albert W Shugg, John K Sinn (2008) <i>Med J Aust</i> <i></i> <i></i> 188: 2 109-112<br/>

http://publicationslist.org/andrew.day/refid32 2010-08-09T10:12:39Z

Probiotics consist of yeast or bacteria, especially lactic acid bacteria. They are available as capsules, powder, fermented milks or yoghurts. Probiotics exhibit strain-specific differences in their resistance to acid and bile, ability to colonise the gastrointestinal tract, clinical efficacy, and benefits to the health of the host. There is level I evidence for the use of probiotics in treating a...<br/><br/>Mimi Pham, Daniel A Lemberg, Andrew S Day (2008) <i>Med J Aust</i> <i></i> <i></i> 188: 5 304-308<br/>

http://publicationslist.org/andrew.day/refid34 2010-08-09T10:12:39Z

BACKGROUND AND AIMS: Eosinophilic esophagitis and celiac disease are distinct gastrointestinal disorders. The present study in children highlights the possible coexistence of these two conditions. This study also analyzes the epidemiological and clinical profiles of these patients. METHODS: The medical records of patients diagnosed with celiac disease from 1 April 1999 to 31 March 2007 were review...<br/><br/>Chee Y Ooi, Andrew S Day, Reuben Jackson, Tim D Bohane, Vivienne Tobias, Daniel A Lemberg (2008) <i>J Gastroenterol Hepatol</i> <i></i> <i></i> 23: 7 Pt 1 1144-1148<br/>

http://publicationslist.org/andrew.day/refid36 2010-08-09T10:12:39Z

BACKGROUND: At least 25% of individuals diagnosed with Crohn's disease (CD) have onset of disease in childhood. Almost all children with CD have nutritional impairments, such as weight loss or stunting, at diagnosis or subsequently. Nutritional therapy (exclusive enteral nutrition) is established as a valid and effective treatment in paediatric CD. The advantages of this approach are induction of ...<br/><br/>A S Day, K E Whitten, M Sidler, D A Lemberg (2008) <i>Aliment Pharmacol Ther</i> <i></i> <i></i> 27: 4 293-307<br/>

http://publicationslist.org/andrew.day/refid37 2010-08-09T10:12:39Z

BACKGROUND: Interleukin-18 (IL-18) is increased in the inflamed mucosa of patients with Crohn's disease (CD). The balance between this pleiotropic proinflammatory cytokine and its natural inhibitor, IL-18-binding protein (IL-18BP), may contribute to the pathogenesis of inflammatory bowel disease (IBD). METHODS: Serum and mucosal biopsies were collected from children with IBD, from children with ce...<br/><br/>Steven T Leach, Isabella Messina, Daniel A Lemberg, Daniela Novick, Menachem Rubenstein, Andrew S Day (2008) <i>Inflamm Bowel Dis</i> <i></i> <i></i> 14: 1 68-74<br/>

http://publicationslist.org/andrew.day/refid31 2010-08-09T10:12:39Z

The expression of the inflammatory S100 calgranulin proteins (S100A8, S100A9 and S100A12) in normal and Helicobacter pylori-infected gastric mucosa of children were examined. S100A8, S100A9 and S100A12, which were virtually absent in normal gastric mucosa, were highly expressed in H pylori-infected mucosa. This expression correlated with the severity of gastritis (r=0.9422, P<0.05). S100 calgranul...<br/><br/>Steven T Leach, Hazel M Mitchell, Carolyn L Geczy, Philip M Sherman, Andrew S Day (2008) <i>Can J Gastroenterol</i> <i></i> <i></i> 22: 5 461-464<br/>

http://publicationslist.org/andrew.day/refid35 2010-08-09T10:12:39Z

BACKGROUND: Fecal calprotectin is a sensitive marker for gut inflammation. Recently, we have established that a related protein, S100A12, is elevated in the feces of children with inflammatory bowel disease (IBD). This may represent a specific and sensitive disease marker. The objective was to investigate the utility of fecal S100A12, in comparison to fecal calprotectin and standard inflammatory m...<br/><br/>Marc A Sidler, Steven T Leach, Andrew S Day (2008) <i>Inflamm Bowel Dis</i> <i></i> <i></i> 14: 3 359-366<br/>

http://publicationslist.org/andrew.day/refid30 2010-08-09T10:12:38Z

With increasing medical knowledge and emphasis upon evidence-based medicine, it is essential for practitioners to have optimal literature searching skills. There are limited data regarding the use of online information retrieval (IR) systems by paediatric junior medical officers (JMO). The aims of this questionnaire-based study of a group of JMO were to assess the accessibility, frequency of use a...<br/><br/>P Shirkhedkar, A S Day (2008) <i>Inform Health Soc Care</i> <i></i> <i></i> 33: 1 69-75<br/>

http://publicationslist.org/andrew.day/refid24 2010-08-09T10:12:38Z

BACKGROUND: The use of exclusive enteral nutrition to treat paediatric Crohn's disease (CD) is widely accepted, although the precise mechanism(s) of action remains speculative. AIM: To investigate the changes to key intestinal bacterial groups of Eubacteria, Bacteroides, Clostridium coccoides, Clostridium leptum and Bifidobacteria, during and after exclusive enteral nutrition treatment for CD in p...<br/><br/>S T Leach, H M Mitchell, W R Eng, L Zhang, A S Day (2008) <i>Aliment Pharmacol Ther</i> <i></i> <i></i> 28: 6 724-733<br/>

http://publicationslist.org/andrew.day/refid27 2010-08-09T10:12:38Z

Coeliac disease (CD) screening has progressed rapidly with tissue transglutaminase (TTG), the screening tool of choice. However, TTG may be unreliable in young children and advances in CD etiology understanding have seen improvements in anti-gliadin (AGA) assay technology. The aim of this study was to investigate the utility of an updated and refined AGA (Neogliadin) assay for CD screening in chil...<br/><br/>Steven T Leach, Brekhna Aurangzeb, Andrew S Day (2008) <i>J Clin Lab Anal</i> <i></i> <i></i> 22: 5 327-333<br/>

http://publicationslist.org/andrew.day/refid26 2010-08-09T10:12:38Z

Richard B Gearry, Andrew S Day (2008) <i>N Z Med J</i> <i></i> <i></i> 121: 1283 5-8<br/>

http://publicationslist.org/andrew.day/refid28 2010-08-09T10:12:38Z

BACKGROUND: Although there is compelling evidence to support the role of bacteria in Crohn's disease (CD), there is currently no solid evidence to support the role of any one specific bacterial causative agent. Recent studies have suggested that members of the Helicobacteraceae may play a role in the development of CD. The aim of this study was to further investigate the presence of members of the...<br/><br/>Si Ming Man, Li Zhang, Andrew S Day, Steven Leach, Hazel Mitchell (2008) <i>Helicobacter</i> <i></i> <i></i> 13: 4 234-238<br/>

http://publicationslist.org/andrew.day/refid29 2010-08-09T10:12:38Z

BACKGROUND: Postnatal growth of the small intestine occurs by crypt hyperplasia and by the less recognised mechanism of crypt fission. How the small intestine grows is largely extrapolated from animals and is poorly described in humans. AIM: To investigate crypt fission and crypt hyperplasia as mechanisms of intestinal growth in humans. PATIENTS AND METHODS: Proximal intestinal samples were taken ...<br/><br/>Adrian G Cummins, Anthony G Catto-Smith, Donald J Cameron, Richard T Couper, Geoffrey P Davidson, Andrew S Day, Paul D Hammond, David J Moore, Fiona M Thompson (2008) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 47: 2 153-157<br/>

http://publicationslist.org/andrew.day/refid40 2010-08-09T10:12:39Z

Probiotics have become increasingly popular and are now promoted as having a wide range of benefits. Probiotics are generally very well tolerated and safe but many of the purported uses are not yet well supported with adequate scientific evidence. Two well-established roles for probiotics in children are acute diarrhoeal illness and antibiotic-associated diarrhoea. This review summarises the evide...<br/><br/>Daniel A Lemberg, Chee Yee Ooi, Andrew S Day (2007) <i>J Paediatr Child Health</i> <i></i> <i></i> 43: 5 331-336<br/>

http://publicationslist.org/andrew.day/refid39 2010-08-09T10:12:39Z

Kirsty Barnett, Phillip Emder, Andrew S Day, Warwick S Selby (2007) <i>Gastrointest Endosc</i> <i></i> <i></i> 66: 3 625-627<br/>

http://publicationslist.org/andrew.day/refid38 2010-08-09T10:12:39Z

OBJECTIVE: Various markers characterize the complex inflammatory processes seen in chronic inflammatory bowel disease (IBD) including calprotectin, a complex of two S100 proteins, which has been evaluated and validated as a faecal marker of inflammation. However, the systemic and mucosal expression patterns of calprotectin and related S100 proteins are not well characterized in this disease. The o...<br/><br/>Steven T Leach, Zheng Yang, Isabella Messina, Changjie Song, Carolyn L Geczy, Anne M Cunningham, Andrew S Day (2007) <i>Scand J Gastroenterol</i> <i></i> <i></i> 42: 11 1321-1331<br/>

http://publicationslist.org/andrew.day/refid41 2010-08-09T10:12:39Z

Exclusive enteral nutrition using polymeric formula (PF) is a well-established therapeutic option for active Crohn's disease; however, its mechanisms of action are unknown. We investigated the anti-inflammatory effects of PF in an in vitro model of epithelial cell inflammation. PF did not affect cell viability over a range of dilutions, but when PF was added to the culture medium the interleukin (...<br/><br/>Naomi S H de Jong, Steven T Leach, Andrew S Day (2007) <i>Dig Dis Sci</i> <i></i> <i></i> 52: 9 2029-2036<br/>

http://publicationslist.org/andrew.day/refid42 2010-08-09T10:12:39Z

BACKGROUND: Measurement of thiopurine metabolite levels may be useful as a clinical tool to optimize thiopurine treatment of paediatric inflammatory bowel disease (IBD). AIM: The authors evaluated correlations between 6-thioguanine nucleotide (6-TGN) and therapeutic response, metabolite levels and drug toxicity. METHODS: Fifty-six paediatric IBD patients treated with thiopurines had 326 metabolite...<br/><br/>C Y Ooi, T D Bohane, D Lee, D Naidoo, A S Day (2007) <i>Aliment Pharmacol Ther</i> <i></i> <i></i> 25: 8 941-947<br/>

http://publicationslist.org/andrew.day/refid44 2010-08-09T10:12:39Z

BACKGROUND: The calcium-binding protein S100A12 is related to calprotectin, a protein shown to be a useful marker of gut inflammation. S100A12 levels are elevated in serum and mucosa of children with inflammatory bowel disease (IBD) and may be implicated in the pathogenesis of IBD. The aims of this study were to validate an immunoassay for the detection of fecal S100A12, to assess its value as a n...<br/><br/>Naomi S H de Jong, Steven T Leach, Andrew S Day (2006) <i>Inflamm Bowel Dis</i> <i></i> <i></i> 12: 7 566-572<br/>

http://publicationslist.org/andrew.day/refid45 2010-08-09T10:12:39Z

Crohn's disease and ulcerative colitis (the inflammatory bowel diseases) are two well characterized conditions featuring inflammation of the gastrointestinal tract. Gut inflammation may be detected, assessed and measured by a variety of methods but their utility varies extensively. Over the past decade, calprotectin, belonging to a family of S100 proteins, has been shown to be a reliable marker of...<br/><br/>Steven T Leach, Andrew S Day (2006) <i>Expert Rev Clin Immunol</i> <i></i> <i></i> 2: 3 471-480<br/>

http://publicationslist.org/andrew.day/refid43 2010-08-09T10:12:39Z

BACKGROUND: Exclusive enteral feeding has been shown to be as efficacious as corticosteroids in inducing remission in children with Crohn's disease (CD), with additional nutritional benefits. The use of polymeric formulae provides superior palatability and acceptance over elemental feeds, but polymeric formulae have not been universally adopted. The present retrospective analysis of enteral feedin...<br/><br/>Andrew S Day, Kylie E Whitten, Daniel A Lemberg, Cathy Clarkson, Maribel Vitug-Sales, Reuben Jackson, Tim D Bohane (2006) <i>J Gastroenterol Hepatol</i> <i></i> <i></i> 21: 10 1609-1614<br/>

http://publicationslist.org/andrew.day/refid52 2010-08-09T10:12:39Z

Daniel Lemberg, Andrew S Day, Barry Wyeth (2005) <i>J Paediatr Child Health</i> <i></i> <i></i> 41: 5-6 291-293<br/>

http://publicationslist.org/andrew.day/refid53 2010-08-09T10:12:39Z

BACKGROUND: To describe the presenting clinical features of coeliac disease in a single paediatric centre, and to determine if the presenting features vary with age. METHODS: A review was conducted of children who had been referred with clinical suspicion of coeliac disease to the paediatric gastroenterology department of a tertiary paediatric hospital in Sydney, Australia. Coeliac disease was def...<br/><br/>Monique L Stone, Timothy D Bohane, Kylie E Whitten, Vivienne H Tobias, Andrew S Day (2005) <i>BMC Pediatr</i> <i></i> <i></i> 5: 1 <br/>

http://publicationslist.org/andrew.day/refid55 2010-08-09T10:12:39Z

AIM: To document the concerns and expectations of parents of children with inflammatory bowel disease (IBD) within the context of a multidisciplinary IBD clinic, and to highlight the importance of a holistic approach to the care of these children. METHODS: The parents of 60 children with IBD were surveyed by mailed questionnaire. Parents were asked to provide details of their concerns regarding th...<br/><br/>A-S Day, K-E Whitten, T-D Bohane (2005) <i>World J Gastroenterol</i> <i></i> <i></i> 11: 7 1028-1031<br/>

http://publicationslist.org/andrew.day/refid50 2010-08-09T10:12:39Z

Orofacial granulomatosis is a term generally used to describe lip swelling secondary to an underlying granulomatous inflammatory process. Granulomatous cheilitis is the histopathological description of such inflammation occurring in the lips and surrounding tissues. Melkersson-Rosenthal syndrome (a triad of orofacial swelling, facial paralysis and a fissured tongue) is one manifestation of orofaci...<br/><br/>J M Khouri, T D Bohane, A S Day (2005) <i>Acta Paediatr</i> <i></i> <i></i> 94: 4 501-504<br/>

http://publicationslist.org/andrew.day/refid54 2010-08-09T10:12:39Z

Clinical pathways are useful tools in improving the quality of care of patients treated in hospitals. Gastroenteritis is a short, self-limiting, but common illness of childhood associated with significant costs to the community. The authors assessed the impact of a clinical pathway on investigation ordering in children with gastroenteritis. A retrospective analysis of 2 cohorts of children was per...<br/><br/>Daniel A Lemberg, Andrew S Day, Michael Brydon (2005) <i>Am J Med Qual</i> <i></i> <i></i> 20: 2 83-89<br/>

http://publicationslist.org/andrew.day/refid51 2010-08-09T10:12:39Z

The incidence of reporting and diagnosis of coeliac disease (CD) in children is increasing with the improvement in sensitivity and specificity of screening markers. This in turn has led to an increasing awareness of gluten-sensitive enteropathy and associated disorders. We report the unusual case of an 8-month-old child presenting to his general practitioner with pruritic skin lesions, subsequentl...<br/><br/>Daniel Lemberg, Andrew S Day, Timothy Bohane (2005) <i>J Paediatr Child Health</i> <i></i> <i></i> 41: 5-6 294-296<br/>

http://publicationslist.org/andrew.day/refid47 2010-08-09T10:12:39Z

INTRODUCTION: Diagnosis of inflammatory bowel disease (IBD) and differentiation between Crohn's disease (CD) and ulcerative colitis (UC) can be difficult in children. Several previous studies suggest that esophagogastroduodenoscopy (EGD) and biopsies are important in the initial investigation of children with suspected IBD. The aim of the present paper was to assess the importance of EGD in the in...<br/><br/>Daniel A Lemberg, Cathy M Clarkson, Timothy D Bohane, Andrew S Day (2005) <i>J Gastroenterol Hepatol</i> <i></i> <i></i> 20: 11 1696-1700<br/>

http://publicationslist.org/andrew.day/refid48 2010-08-09T10:12:39Z

BACKGROUND: Gastric epithelial cell lines have been utilized extensively as tools to define aspects of the interactions between Helicobacter pylori and host epithelial cells. Fetal calf serum (FCS) is employed as a growth stimulant, but it is unclear whether this agent may in itself alter host responses. METHODS: Two gastric epithelial cell lines were utilized to ascertain the effects of varying F...<br/><br/>Daniel Sieveking, Steven T Leach, Hazel M Mitchell, Andrew S Day (2005) <i>J Gastroenterol Hepatol</i> <i></i> <i></i> 20: 10 1610-1615<br/>

http://publicationslist.org/andrew.day/refid46 2010-08-09T10:12:39Z

Andrew S Day (2005) <i>Expert Rev Clin Immunol</i> <i></i> <i></i> 1: 4 489-492<br/>

http://publicationslist.org/andrew.day/refid49 2010-08-09T10:12:39Z

Vomiting and abdominal symptoms are uncommonly seen in children with Prader-Willi syndrome (PWS). A case is described of a child with PWS who presented with vomiting, abdominal distension and abdominal pain due to a duodenal web causing gross gastric distension. Prompt attention to the onset of such clinical features in children with PWS may prevent excess morbidity and complications.<br/><br/>Maribel I Vitug-Sales, Daniel A Lemberg, Clare Cunningham, Guy Henry, Andrew S Day (2005) <i>J Paediatr Child Health</i> <i></i> <i></i> 41: 9-10 527-528<br/>

http://publicationslist.org/andrew.day/refid59 2010-08-09T10:12:39Z

Brendan Drumm, Andrew S Day, Ben Gold, Frederic Gottrand, Seiichi Kato, Elisabete Kawakami, Armando Madrazo, John Snyder, Julian Thomas (2004) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 39 Suppl 2: S626-S631<br/>

http://publicationslist.org/andrew.day/refid60 2010-08-09T10:12:39Z

OBJECTIVE: Although there are published guidelines representing the consensus of several large groups, it is unclear whether these are used by practitioners in the management of Helicobacter pylori infection in children and if the guidelines are relevant to particular regions of the world. The aim of this study was to answer these questions in regard to the Australasian region. METHODS: An email-b...<br/><br/>A S Day, H M Mitchell, T D Bohane (2004) <i>J Paediatr Child Health</i> <i></i> <i></i> 40: 4 195-200<br/>

http://publicationslist.org/andrew.day/refid58 2010-08-09T10:12:39Z

BACKGROUND AND AIMS: Helicobacter pylori infection of the stomach is commonly associated with infiltration of neutrophils. Gastric epithelial cells are recognized as central mediators of tissue responses to this organism. The aim of the present study was to ascertain patterns of production of three neutrophil chemoattractant chemokines following infection of gastric epithelial cells with H. pylori...<br/><br/>Daniel Sieveking, Hazel M Mitchell, Andrew S Day (2004) <i>J Gastroenterol Hepatol</i> <i></i> <i></i> 19: 9 982-987<br/>

http://publicationslist.org/andrew.day/refid57 2010-08-09T10:12:39Z

OBJECTIVES: The use of complementary and alternative medicines (CAM) appears increasingly prevalent in children and adolescents. Individuals with chronic illness may have patterns of greater usage. This questionnaire-based study aimed to ascertain the frequency of use by a group of children with proven inflammatory bowel disease (IBD) and to consider the reasons for their use. METHODS: A questionn...<br/><br/>A S Day, K E Whitten, T D Bohane (2004) <i>J Paediatr Child Health</i> <i></i> <i></i> 40: 12 681-684<br/>

http://publicationslist.org/andrew.day/refid56 2010-08-09T10:12:39Z

Helicobacter pylori colonization of the stomach results in a chronic-active gastritis characterized by mucosal infiltration of both neutrophils and lymphocytes. A T helper lymphocyte (Th1) profile predominates, which promotes the chronic and persistent inflammatory changes in the gastric mucosa in response to this bacterial pathogen. The cytokine interleukin-18 induces production of interferon-gam...<br/><br/>Andrew S Day, Bin Su, Peter J M Ceponis, Nicola L Jones, Edwin Yau, Daniel Sieveking, Philip M Sherman (2004) <i>Dig Dis Sci</i> <i></i> <i></i> 49: 11-12 1830-1835<br/>

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Intestinal lymphangiectasia is a well-recognized complication of the Fontan procedure, occurring in up to 24% of patients. Because of the loss of chylous fluid into the gut lumen, protein-losing enteropathy results as well as lymphopenia and hypogammaglobulinaemia. In some cases, dilated lymphatics in the intestinal serosa or mesentery also rupture, causing chylous ascites. Standard medical and ca...<br/><br/>Frances L Connor, Socrates Angelides, Miriam Gibson, Dale W Larden, Marcin R Roman, Owen Jones, Bruce G Currie, Andrew S Day, Timothy D Bohane (2003) <i>Pediatrics</i> <i></i> <i></i> 112: 3 Pt 1 e242-e247<br/>

http://publicationslist.org/andrew.day/refid61 2010-08-09T10:12:39Z

BACKGROUND: An accurate diagnosis of Helicobacter pylori infection in children currently relies upon histological assessment or culture of gastric biopsies obtained at endoscopy. Noninvasive testing would permit simpler assessment of children with dyspeptic symptoms. The primary aim of the present study was to prospectively evaluate a novel urea breath testing method in children undergoing diagnos...<br/><br/>Andrew S Day, Sander Veldhuyzen van Zanten, Anthony R Otley, Linda Best, AnneMarie Griffiths, Philip M Sherman (2003) <i>Can J Gastroenterol</i> <i></i> <i></i> 17: 12 701-706<br/>

http://publicationslist.org/andrew.day/refid67 2010-08-09T10:12:39Z

OBJECTIVES: Complementary and alternative medicines (CAM) and probiotic therapies appear to be increasingly accepted and used. This questionnaire-based study aimed to ascertain the frequency of use and the acceptance of these therapies by children attending outpatient gastroenterology clinics. METHODS: Parents accompanying children to their appointments were asked to complete a questionnaire in or...<br/><br/>A S Day (2002) <i>J Paediatr Child Health</i> <i></i> <i></i> 38: 4 343-346<br/>

http://publicationslist.org/andrew.day/refid68 2010-08-09T10:12:39Z

BACKGROUND: Rapid non-invasive diagnostic tests that can reliably document the presence or absence of Helicobacter pylori infection are urgently required. The aim of this study was to determine the accuracy of two immunoassays (Flex-Sure and MedMira), developed for use outside the laboratory setting by practitioners, in the setting of a low prevalence of H. pylori infection. METHODS: Serum samples...<br/><br/>Andrew S Day, Philip M Sherman (2002) <i>Helicobacter</i> <i></i> <i></i> 7: 3 205-209<br/>

http://publicationslist.org/andrew.day/refid69 2010-08-09T10:12:39Z

Recent evidence suggests that immune-mediated gastric epithelial cell apoptosis through Fas-Fas ligand interactions participates in Helicobacter pylori disease pathogenesis. To define the role of Fas signaling in vivo, H. pylori strain SS1 infection in C57BL/6 mice was compared to that in mice deficient in the Fas ligand (gld). gld mice had a degree of gastritis similar to that of C57BL/6 mice aft...<br/><br/>Nicola L Jones, Andrew S Day, Hilary Jennings, Patrick T Shannon, Esther Galindo-Mata, Philip M Sherman (2002) <i>Infect Immun</i> <i></i> <i></i> 70: 5 2591-2597<br/>

http://publicationslist.org/andrew.day/refid66 2010-08-09T10:12:39Z

OBJECTIVES: Aspiration of gastric contents is a relatively common cause of acute and chronic pulmonary disease. However, a reliable method of diagnosing recurrent aspiration is currently lacking. The aim of this study was to determine whether the presence of gastric pepsin in tracheal aspirates of infants and children might be used as a reliable marker of the microaspiration of refluxed gastric co...<br/><br/>Usha Krishnan, John D Mitchell, Isabella Messina, Andrew S Day, Timothy D Bohane (2002) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 35: 3 303-308<br/>

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OBJECTIVES: Refluxed gastric material aspirated into the lungs is an important cause of acute and chronic pulmonary disease. Currently, the presence of fat-laden macrophages (FLM) in tracheobronchial secretions of children is a conventional marker for reflux aspiration. However, this assay is limited by its apparent lack of specificity. The aim of this study was to reevaluate the role of this assa...<br/><br/>Usha Krishnan, John D Mitchell, Vivian Tobias, Andrew S Day, Timothy D Bohane (2002) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 35: 3 309-313<br/>

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Annabel L Buxton, Alexander J Barber, Tim D Bohane, Andrew S Day (2002) <i>N Z Med J</i> <i></i> <i></i> 115: 1167 <br/>

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M O Stormon, J D Mitchell, J S Smoleniec, V Tobias, A S Day (2002) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 35: 5 691-694<br/>

http://publicationslist.org/andrew.day/refid70 2010-08-09T10:12:39Z

Gastric infection with Helicobacter pylori results in chronic active gastritis and in some individuals is associated with complications such as peptic ulceration and gastric cancers. A balance between bacterial factors and host responses may determine disease outcome. The mouse-adapted H. pylori strain SS1 has been utilized as a model to study disease pathogenesis. Although chronic gastritis is ob...<br/><br/>A S Day, N L Jones, Z Policova, H A Jennings, E K Yau, P Shannon, A W Neumann, P M Sherman (2001) <i>Dig Dis Sci</i> <i></i> <i></i> 46: 9 1943-1951<br/>

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AIMS: To evaluate the short and long term morbidity of gastrostomy insertion, and to identify ongoing management requirements. METHODS: A retrospective review was undertaken of the hospital casenotes of children aged up to fifteen years who had a gastrostomy placed in Christchurch over a six year period to March 1998. RESULTS: 42 children had a gastrostomy fashioned, 35 in the last three years of ...<br/><br/>A S Day, S W Beasley, A Meads, G D Abbott (2001) <i>N Z Med J</i> <i></i> <i></i> 114: 1129 164-167<br/>

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This study was undertaken to determine whether infection with Helicobacter pylori strains that contain the cagE gene was associated with duodenal ulceration in children. The presence of flaA, cagA, and cagE genes was determined by polymerase chain reaction in H. pylori previously cultured from 29 children. Twelve (92%) of 13 children with duodenal ulcers were infected with cagE-positive isolates, ...<br/><br/>A S Day, N L Jones, J T Lynett, H A Jennings, C A Fallone, R Beech, P M Sherman (2000) <i>J Infect Dis</i> <i></i> <i></i> 181: 4 1370-1375<br/>

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A S Day, P M Sherman (2000) <i>Pediatr Res</i> <i></i> <i></i> 47: 6 <br/>

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A S Day, N L Jones (2000) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 30: 3 344-345<br/>

http://publicationslist.org/andrew.day/refid73 2010-08-09T10:12:39Z

OBJECTIVE: To evaluate the efficacy of oral tacrolimus as an induction agent in steroid-refractory severe colitis. STUDY DESIGN: Open-label, multicenter trial of oral tacrolimus in patients with severe colitis. Patients not responding to conventional therapy received tacrolimus, 0.1 mg/kg/dose given twice a day, and the dosage was adjusted to achieve blood levels between 10 and 15 ng/mL. Response ...<br/><br/>A Bousvaros, B S Kirschner, S L Werlin, L Parker-Hartigan, F Daum, K B Freeman, J P Balint, A S Day, A M Griffiths, D Zurakowski, G D Ferry, A M Leichtner (2000) <i>J Pediatr</i> <i></i> <i></i> 137: 6 794-799<br/>

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AIMS: To determine the prevalence of coeliac disease in selected groups of children presenting to a paediatric department. METHODS: Children presenting to the Paediatric Department at Christchurch Hospital were enrolled upon identification of one or more factors associated with increased risk of coeliac disease. All subjects were screened with anti-endomysial antibody and antigliadin antibody test...<br/><br/>A S Day, H B Cook, M Whitehead, G D Abbott (2000) <i>N Z Med J</i> <i></i> <i></i> 113: 1119 412-413<br/>

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Coeliac disease and inflammatory bowel disease (IBD) individually are not uncommon in children, but the occurrence of both conditions together is rare. The combined presentation of coeliac disease and IBD in a girl of 7 years is presented with a review of the related literature. The occurrence of coeliac disease with IBD should be considered at the time of diagnosis and at relapse, or where there ...<br/><br/>A S Day, G D Abbott (1999) <i>J Paediatr Child Health</i> <i></i> <i></i> 35: 2 204-206<br/>

http://publicationslist.org/andrew.day/refid81 2010-08-09T10:12:39Z

Helicobacter pylori causes chronic active (type B) gastritis in the overwhelming majority of infected individuals. The relative contribution of virulence factors in the bacterium and host responses to the microbial infection in determining which subjects will go on to develop complications - such as peptic ulceration, gastric cancers and gastric lymphomas - is the subject of current investigative ...<br/><br/>A S Day, P M Sherman (1999) <i>Can J Gastroenterol</i> <i></i> <i></i> 13: 3 229-234<br/>

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The mechanisms involved in mediating the enhanced gastric epithelial cell apoptosis observed during infection with Helicobacter pylori in vivo are unknown. To determine whether H. pylori directly induces apoptosis of gastric epithelial cells in vitro and to define the role of the Fas-Fas ligand signal transduction cascade, human gastric epithelial cells were infected with H. pylori for up to 72 h ...<br/><br/>N L Jones, A S Day, H A Jennings, P M Sherman (1999) <i>Infect Immun</i> <i></i> <i></i> 67: 8 4237-4242<br/>

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Helicobacter pylori infection is primarily acquired during childhood, causes chronic, active gastritis and peptic ulcer disease, and is associated with the development of gastric malignancies. However, only a small number of infected individuals ever develop the more severe sequelae of peptic ulcer disease and gastric cancers. Therefore, the identification of bacterial and host factors that play a...<br/><br/>N L Jones, A S Day, P M Sherman (1999) <i>Can J Gastroenterol</i> <i></i> <i></i> 13: 7 613-317<br/>

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Short bowel syndrome can present many complex management issues and may be complicated by various metabolic problems. D-lactic acidosis in the setting of short bowel syndrome has been described only rarely in children. A further case is presented with a review of typical clinical manifestations of D-lactic acidosis and reported management options. Early recognition and appropriate management is es...<br/><br/>A S Day, G D Abbott (1999) <i>N Z Med J</i> <i></i> <i></i> 112: 1092 277-278<br/>

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A S Day, D O McGregor, S J Henderson, D W Teele (1998) <i>Pediatr Infect Dis J</i> <i></i> <i></i> 17: 1 83-85<br/>