http://publicationslist.org/data/androniki.tosca/atom.xml Androniki Toscahttp://publicationslist.org/androniki.tosca$basepathfavicon.icoRecent additions to Androniki Tosca's PublicationsList.org pagehttp://publicationslist.org/publications.png2010-10-27T12:08:56Z http://publicationslist.org/androniki.tosca/refid2 2010-10-25T09:22:20Z

The co-expression of KIT receptor and its ligand stem cell factor (SCF) has been reported in biopsy specimens of Merkel cell carcinoma (MCC). However, the functional role of SCF/KIT in the pathogenesis of this aggressive tumor has not been elucidated. The present study reports expression and effects of SCF and KIT in the Merkel cell carcinoma cell line MCC-1 in vitro. SCF and KIT were endogenously...<br/><br/>Konstantin Krasagakis, Irene Fragiadaki, Maria Metaxari, Sabine Krüger-Krasagakis, George N Tzanakakis, Efstathios N Stathopoulos, Jürgen Eberle, Nektarios Tavernarakis, Androniki D Tosca (2010) <i>J Cell Physiol</i> <i></i> <i></i> : <br/>

http://publicationslist.org/androniki.tosca/refid40 2010-10-25T09:22:20Z

Background  Psoriasis is a chronic inflammatory skin disease associated with abnormal vascular expansion in the papillary dermis. Tumour necrosis factor (TNF)-α is a proinflammatory cytokine that can induce antiapoptotic proteins and endothelial cell activation factors in psoriasis. Objectives  The present study investigated the effect of the anti-TNF-α agent etanercept on the expression of ...<br/><br/>G Avramidis, S Krüger-Krasagakis, K Krasagakis, I Fragiadaki, G Kokolakis, A Tosca (2010) <i>Br J Dermatol</i> <i></i> <i></i> : <br/>

http://publicationslist.org/androniki.tosca/refid41 2010-10-25T09:22:20Z

P Papadantonakis, O Neofotistou, A Vasiliadi, A Skoutelis, A Tsatsakis, A Tosca, S Krüger-Krasagakis (2010) <i>J Eur Acad Dermatol Venereol</i> <i></i> <i></i> : <br/>

http://publicationslist.org/androniki.tosca/refid3 2010-10-25T09:22:20Z

Recent whole-genome and candidate-gene association studies in patients with psoriasis (PS) have identified a number of single-nucleotide polymorphisms (SNPs) that predispose to disease with moderate risk. Predisposition to PS is known to be affected by genetic variation in human leukocyte antigen-C as well as other non-human leukocyte antigen genes. We recently reported for the first time as a PS-...<br/><br/>Maria I Zervou, Francesc Castro-Giner, Prodromos Sidiropoulos, Dimitrios T Boumpas, Androniki D Tosca, Sabine Krueger-Krasagakis (2010) <i>Genet Test Mol Biomarkers</i> <i></i> <i></i> 14: 1 107-111<br/>

http://publicationslist.org/androniki.tosca/refid1 2010-10-25T09:22:20Z

BACKGROUND: Erysipelas is a superficial form of cellulitis affecting the upper dermis and superficial lymphatics. The widespread use of antibiotics may affect clinical findings and response to therapy of infectious disorders. The purpose of the study was to investigate the epidemiological, clinical, and laboratory features of erysipelas and to compare the results of treatment with penicillin vs. o...<br/><br/>Konstantin Krasagakis, Antonios Valachis, Panagiotis Maniatakis, Sabine Krüger-Krasagakis, George Samonis, Androniki D Tosca (2010) <i>Int J Dermatol</i> <i></i> <i></i> 49: 9 1012-1017<br/>

http://publicationslist.org/androniki.tosca/refid6 2010-10-25T09:22:20Z

BACKGROUND: Treatment of multiple cutaneous piloleiomyomas which are rare, frequently painful, benign tumors originating from the arrector pilorum muscle of hair follicles is difficult. OBJECTIVE: To determine the efficiency of botulinum toxin type A (BT-A) treatment for pain relief of cutaneous piloleiomyomas. Methods: A patient with multiple painful piloleiomyomas was treated with local injectio...<br/><br/>Maria K Sifaki, Sabine Krueger-Krasagakis, Anastasios Koutsopoulos, Georgios I Evangelou, Androniki D Tosca (2009) <i>Dermatology</i> <i></i> <i></i> 218: 1 44-47<br/>

http://publicationslist.org/androniki.tosca/refid4 2010-10-25T09:22:20Z

Recent genome-wide association studies (GWAS) of many complex diseases have successfully identified novel susceptibility loci, with many of them being associated with more than one condition. Taking into consideration that different autoimmune diseases may share some common pathogenetic pathways, we hypothesized that STAT4, a susceptibility gene found to be associated with increased risk for syste...<br/><br/>Maria I Zervou, George N Goulielmos, Francesc Castro-Giner, Androniki D Tosca, Sabine Krueger-Krasagakis (2009) <i>Hum Immunol</i> <i></i> <i></i> 70: 9 738-741<br/>

http://publicationslist.org/androniki.tosca/refid5 2010-10-25T09:22:20Z

BACKGROUND/AIMS: KIT receptor has been implicated in the pathogenesis of cancer, either by mutation or autocrine activation. Merkel cell carcinoma (MCC) is a rare KIT-positive cutaneous tumor. We investigated the co-expression of KIT and its ligand stem cell factor (SCF) in MCC. METHODS: Sixteen specimens from 13 MCC patients of various tumor stages were examined by immunohistochemistry for SCF, K...<br/><br/>Konstantin Krasagakis, Sabine Kruger-Krasagakis, Jürgen Eberle, Aristidis Tsatsakis, Androniki D Tosca, Efstathios N Stathopoulos (2009) <i>Dermatology</i> <i></i> <i></i> 218: 1 37-43<br/>

http://publicationslist.org/androniki.tosca/refid7 2010-10-25T09:22:20Z

Merkel cell carcinoma is a tumor with aggressive biological behavior and limited response to chemotherapy. The present study investigated the effect of interferon (IFN)-alpha on growth and apoptosis of Merkel carcinoma cells in vitro. Proliferation of MCC-1 cell line was reduced dose-dependently by IFN-alpha and diminished when higher IFN-alpha concentrations were used. Additionally, IFN-alpha pot...<br/><br/>Konstantin Krasagakis, Sabine Krüger-Krasagakis, George N Tzanakakis, Katherine Darivianaki, Efstathios N Stathopoulos, Androniki D Tosca (2008) <i>Cancer Invest</i> <i></i> <i></i> 26: 6 562-568<br/>

http://publicationslist.org/androniki.tosca/refid8 2010-10-25T09:22:20Z

A 64-year-old woman presented with erythematous, infiltrative plaques with a central atrophic area on both zygomatic regions. Several yellow-reddish papules were seen at the periphery of the plaques and showed an "apple-jelly" color on diascopy (Fig. 1). No visceral involvement was detected. The past medical history revealed that, at 3 years of age, she had developed an "Oriental sore" on both che...<br/><br/>Maria P Stefanidou, Maria Antoniou, Athanassios V Koutsopoulos, Yiannakis T Neofytou, Konstantinos Krasagakis, Sabine Krüger-Krasagakis, Yiannis Tselentis, Adroniki D Tosca (2008) <i>Int J Dermatol</i> <i></i> <i></i> 47: 6 588-589<br/>

http://publicationslist.org/androniki.tosca/refid43 2010-10-25T09:22:20Z

Transforming growth factor-beta (TGF-beta), a potent inhibitor of normal melanocyte growth, does not significantly suppress growth of melanoma cells. The mechanism of melanocyte desensitization to TGF-beta in the transformation process remains largerly unknown. We investigated whether the tumor promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) may induce melanocyte resistance to T...<br/><br/>Melanthia Stavroulaki, Dimitris Kardassis, Ekaterini Chatzaki, George Sakellaris, Carsten Lindschau, Hermann Haller, Androniki Tosca, Konstantin Krasagakis (2008) <i>J Cell Physiol</i> <i></i> <i></i> 214: 2 363-370<br/>

http://publicationslist.org/androniki.tosca/refid42 2010-10-25T09:22:20Z

Quantitative immunohistochemistry is needed in order to reliably and accurately assess the expression of cellular proteins in tissue. Skin is a difficult tissue for automated image analysis due to its heterogeneous composition and its architecture. In the present study we used a psoriatic skin model to compare the expression of p53 and bcl-2 before and after treatment with anti-tumor necrosis fact...<br/><br/>Georgios Kokolakis, Lambros Panagis, Efstathios Stathopoulos, Elpida Giannikaki, Androniki Tosca, Sabine Krüger-Krasagakis (2008) <i>J Immunol Methods</i> <i></i> <i></i> 331: 1-2 140-146<br/>

http://publicationslist.org/androniki.tosca/refid44 2010-10-25T09:22:20Z

A rare case of an invasive cutaneous infection by Geotrichum candidum in an 80-year-old male patient with diabetes mellitus is reported. The primary site of infection manifested after trauma as an ulcerative lesion on the distal phalanx of the midfinger and extended throughout the right hand. Histological examination showed fungal invasion in the deep dermis without vascular involvement and G. can...<br/><br/>Andreas Sfakianakis, Konstantin Krasagakis, Maria Stefanidou, Sofia Maraki, Anastassios Koutsopoulos, Diamantis Kofteridis, George Samonis, Androniki Tosca (2007) <i>Med Mycol</i> <i></i> <i></i> 45: 1 81-84<br/>

http://publicationslist.org/androniki.tosca/refid124 2010-10-25T12:53:33Z

K. Krasagakis, G. Samonis, A. Tosca. (2007) <i>Dermatology </i> 214: 192-193<br/>

http://publicationslist.org/androniki.tosca/refid13 2010-10-25T09:22:20Z

BACKGROUND: Tumour necrosis factor (TNF)-alpha blockade using infliximab, a chimeric anti-TNF-alpha antibody, is an effective treatment for plaque-type psoriasis, inducing remission in about 80% of patients. OBJECTIVES: To examine infliximab-induced programmed cell death (PCD) of keratinocytes in psoriatic plaques on serial skin biopsy samples. METHODS: Five patients with moderate to severe plaque...<br/><br/>S Krüger-Krasagakis, V K Galanopoulos, L Giannikaki, M Stefanidou, A D Tosca (2006) <i>Br J Dermatol</i> <i></i> <i></i> 154: 3 460-466<br/>

http://publicationslist.org/androniki.tosca/refid50 2010-10-25T09:22:20Z

BACKGROUND: Erysipelas is a bacterial infection of the dermis and hypodermis, mostly of streptococcal origin. Bullous erysipelas represents a severe form of the disease. OBJECTIVE: To evaluate the clinical and microbiological characteristics and treatment of bullous erysipelas. METHODS: Patients with a diagnosis of bullous erysipelas who were treated at the Department of Dermatology, University Ho...<br/><br/>Konstantin Krasagakis, George Samonis, Panagiotis Maniatakis, Sophia Georgala, Androniki Tosca (2006) <i>Dermatology</i> <i></i> <i></i> 212: 1 31-35<br/>

http://publicationslist.org/androniki.tosca/refid48 2010-10-25T09:22:20Z

BACKGROUND: Onychomycosis represents the most frequently encountered nail disease, which is difficult to eradicate with drug treatment. Epidemiological studies concerning onychomycosis have been performed in many countries worldwide. Differences in the incidence of onychomycosis have been reported not only for various geographical areas, but also for different regions of the same country. OBJECTIV...<br/><br/>D J Ioannidou, S Maraki, S K Krasagakis, A Tosca, Y Tselentis (2006) <i>J Eur Acad Dermatol Venereol</i> <i></i> <i></i> 20: 2 170-174<br/>

http://publicationslist.org/androniki.tosca/refid45 2010-10-25T09:22:20Z

BACKGROUND: Comparative analysis of the incidence rates and epidemiological features of cutaneous malignant melanoma (CMM) between different ethnic groups exposed to varying environmental factors is critical for consideration of the causes of CMM but can also be utilized in a public health approach to control of the disease. OBJECTIVES: To compare incidence rates and clinical features of CMM in a ...<br/><br/>K Lasithiotakis, U Leiter, S Krüger-Krasagakis, A Tosca, C Garbe (2006) <i>Br J Dermatol</i> <i></i> <i></i> 154: 6 1123-1127<br/>

http://publicationslist.org/androniki.tosca/refid46 2010-10-25T09:22:20Z

BACKGROUND: For Greece, no data regarding the incidence of cutaneous melanoma (CM) have been reported. In this report, we present epidemiologic data for CM on Crete, an island in southern Greece, during the years 1999-2002. We attempt a comparison with corresponding data reported for the Italian population. METHODS: One hundred and two CM patients of Cretan origin with primary CM first diagnosed b...<br/><br/>Konstantinos Lasithiotakis, Sabine Krüger-Krasagakis, Aglaia Manousaki, Despina Ioannidou, Ioannis Panagiotides, Androniki Tosca (2006) <i>Int J Dermatol</i> <i></i> <i></i> 45: 4 397-401<br/>

http://publicationslist.org/androniki.tosca/refid47 2010-10-25T09:22:20Z

OBJECTIVES: Primary biliary cirrhosis (PBC), a disease of probable autoimmune etiology that affects the small intrahepatic bile ducts of mainly middle-aged women is commonly associated with pruritus, xanthomatous lesions, and melanosis. We conducted a prospective study to systematically describe the skin disorders of a group of PBC patients. METHODS: A prospective evaluation and analysis of dermat...<br/><br/>Meri Koulentaki, Despina Ioannidou, Maria Stefanidou, Sofia Maraki, I Drigiannakis, Philippas Dimoulios, Jean Marie Enele Melono, Androniki Tosca, Elias A Kouroumalis (2006) <i>Am J Gastroenterol</i> <i></i> <i></i> 101: 3 541-546<br/>

http://publicationslist.org/androniki.tosca/refid12 2010-10-25T09:22:20Z

BACKGROUND: In Greece where primary health care services are not fully developed, patients with simple or minor conditions have to attend to hospitals to be treated. We analysed the data of patients with cutaneous disorders attending the tertiary referral hospital on the Island of Crete, with the aim to identify the most common conditions that patients complain of, in order to define the areas whe...<br/><br/>Emmanouil K Symvoulakis, Konstantin Krasagakis, Ioannis D Komninos, Ioannis Kastrinakis, Ioannis Lyronis, Anastasios Philalithis, Androniki D Tosca (2006) <i>BMC Fam Pract</i> <i></i> <i></i> 7: <br/>

http://publicationslist.org/androniki.tosca/refid49 2010-10-25T09:22:20Z

Despina Ioannidou, John Panayiotides, Konstantin Krasagakis, Maria Stefanidou, Andreas Manios, Androniki Tosca (2006) <i>Int J Dermatol</i> <i></i> <i></i> 45: 1 53-55<br/>

http://publicationslist.org/androniki.tosca/refid9 2010-10-25T09:22:20Z

BACKGROUND: For early melanoma diagnosis, experienced dermatologists have an accuracy of 64-80% using clinical diagnostic criteria, usually the ABCD rule, while automated melanoma diagnosis systems are still considered to be experimental and serve as adjuncts to the naked-eye expert prediction. In an attempt to aid in early melanoma diagnosis, we developed an image processing program with the aim ...<br/><br/>Aglaia G Manousaki, Andreas G Manios, Evgenia I Tsompanaki, John G Panayiotides, Dimitris D Tsiftsis, Anastasia K Kostaki, Androniki D Tosca (2006) <i>Int J Dermatol</i> <i></i> <i></i> 45: 4 402-410<br/>

http://publicationslist.org/androniki.tosca/refid11 2010-10-25T09:22:20Z

Melanocytic nevi are recognized as precursors of melanoma. Aiding in early recognition of melanoma, we estimated color texture parameters, fractal dimension and lacunarity of melanoma and other melanocytic nevi. Digital images of the lesions were processed. Graphic three-dimensional pseudoelevation images of the lesions and surrounding skin were produced to identify irregularities in color texture...<br/><br/>Aglaia G Manousaki, Andreas G Manios, Evgenia I Tsompanaki, Androniki D Tosca (2006) <i>Comput Biol Med</i> <i></i> <i></i> 36: 4 419-427<br/>

http://publicationslist.org/androniki.tosca/refid10 2010-10-25T09:22:20Z

M P Stefanidou, M Chatzaki, K G Lasithiotakis, D J Ioannidou, A D Tosca (2006) <i>J Eur Acad Dermatol Venereol</i> <i></i> <i></i> 20: 4 486-487<br/>

http://publicationslist.org/androniki.tosca/refid14 2010-10-25T09:22:20Z

Scleredema adultorum is a rare sclerotic disorder characterized by diffuse swelling and nonpitting induration of the skin. Its occurrence has been documented in association with infections, diabetes mellitus, paraproteinemia, multiple myeloma, and monoclonal gammopathy. We report an unusual case of a 48-year-old man with an asymptomatic bilateral eyelid edema of sudden onset. During a period of 6 ...<br/><br/>Despina I Ioannidou, Konstantin Krasagakis, Maria P Stefanidou, Spyros Karampekios, John Panayiotidis, Androniki D Tosca (2005) <i>J Am Acad Dermatol</i> <i></i> <i></i> 52: 2 Suppl 1 41-44<br/>

http://publicationslist.org/androniki.tosca/refid52 2010-10-25T09:22:20Z

The aim of this study was to reveal differences in the epidemiology and to identify significant risk factors for cutaneous melanoma (CM) in a relatively dark-skinned, chronically sun-exposed Caucasian population. This group is considered to have a low risk for this tumour. One hundred and ten newly diagnosed patients with primary CM and 110 age- and gender-matched controls, all of Cretan origin, w...<br/><br/>Konstantinos Lasithiotakis, Sabine Krüger-Krasagakis, Despina Ioannidou, Ioannis Pediaditis, Androniki Tosca (2004) <i>Eur J Cancer</i> <i></i> <i></i> 40: 16 2502-2507<br/>

http://publicationslist.org/androniki.tosca/refid54 2010-10-25T09:22:20Z

Konstantin Krasagakis, Sabine Krüger-Krasagakis, Despina Ioannidou, Androniki Tosca (2004) <i>J Am Acad Dermatol</i> <i></i> <i></i> 50: 4 651-652<br/>

http://publicationslist.org/androniki.tosca/refid53 2010-10-25T09:22:20Z

We report a case of cutaneous alternariosis in a 69-year-old male patient. During hospitalization for treatment of the skin disorder, acute myeloid leukaemia was diagnosed. He received multiple chemotherapeutic agents but the leukaemia remained refractory to therapy and the patient died. The clinical picture, diagnosis and treatment of cutaneous alternariosis will be discussed and a review of the ...<br/><br/>D Ioannidou, S Maraki, S Krüger Krasagakis, M Stefanidou, K Krasagakis, M Alexandrakis, A Tosca (2004) <i>Mycoses</i> <i></i> <i></i> 47: 5-6 227-230<br/>

http://publicationslist.org/androniki.tosca/refid51 2010-10-25T09:22:20Z

M Stefanidou, D Ioannidou, J Panayotides, A Tosca (2004) <i>Int J Dermatol</i> <i></i> <i></i> 43: 12 958-961<br/>

http://publicationslist.org/androniki.tosca/refid55 2010-10-25T09:22:20Z

The aim of this work was to present an efficient and objective method of wound healing assessment based on serial measurements of ulcer dimensions and calculation of wound margin advancement towards the center of the lesion. The method is implemented via computer software, which permits clinicians to perform necessary computations. The proposed method of wound assessment integrates pieces of work ...<br/><br/>Andreas Manios, Androniki Tosca, Evaggelos Volakakis, Moshoula Leivadara, Dimitris Tsiftsis (2003) <i>Comput Biol Med</i> <i></i> <i></i> 33: 4 311-317<br/>

http://publicationslist.org/androniki.tosca/refid123 2010-10-25T12:50:52Z

Ioannidou D, Krasagakis K, Panayiotidis J, Stefanidou M, Alexandrakis M, Tosca A. (2003) <i>J Eur Acad Dermatol Venereol </i> 17(6): 702-705<br/>

http://publicationslist.org/androniki.tosca/refid16 2010-10-25T09:22:20Z

Konstantin Krasagakis, Androniki D Tosca (2003) <i>Int J Dermatol</i> <i></i> <i></i> 42: 9 669-676<br/>

http://publicationslist.org/androniki.tosca/refid15 2010-10-25T09:22:20Z

BACKGROUND: Topical application of 5-aminolaevulinic acid (ALA) to condylomata acuminata leads to accumulation of protoporphyrin IX (PpIX); therefore ALA-induced photodynamic therapy (ALA-PDT) appears to be a potential treatment. OBJECTIVES: To investigate in vivo the PpIX fluorescence time course after topical application of ALA in order to determine the optimal time for irradiation, and to asses...<br/><br/>I M Stefanaki, S Georgiou, G C Themelis, E M Vazgiouraki, A D Tosca (2003) <i>Br J Dermatol</i> <i></i> <i></i> 149: 5 972-976<br/>

http://publicationslist.org/androniki.tosca/refid17 2010-10-25T09:22:20Z

We report a case of Netherton syndrome manifested as congenital ichthyosiform erythroderma, trichorrhexis invaginata and atopy, who in early adulthood developed multiple, aggressive epithelial neoplasms in sun-exposed areas of the skin, in areas with papillomatous skin hyperplasia and at the left parotid region. The occurrence of cutaneous neoplasia has been reported in syndromes with congenital i...<br/><br/>K Krasagakis, D J Ioannidou, M Stephanidou, A Manios, J G Panayiotides, A D Tosca (2003) <i>Dermatology</i> <i></i> <i></i> 207: 2 182-184<br/>

http://publicationslist.org/androniki.tosca/refid18 2010-10-25T09:22:20Z

Despina J Ioannidou, Konstantin Krasagakis, Eugene K Daphnis, Konstantinos E Perakis, Flora Sotsiou, Androniki D Tosca (2002) <i>Arch Dermatol</i> <i></i> <i></i> 138: 3 412-414<br/>

http://publicationslist.org/androniki.tosca/refid122 2010-10-25T12:48:51Z

Ioannidou D, Krasagakis K, Stefanidou M, Tosca A. (2002) <i>Clinical & Exper Dermatology</i> 27: 720<br/>

http://publicationslist.org/androniki.tosca/refid56 2010-10-25T09:22:20Z

D Ioannidou, K Krasagakis, M Stefanidou, A Tosca (2002) <i>Clin Exp Dermatol</i> <i></i> <i></i> 27: 8 720-722<br/>

http://publicationslist.org/androniki.tosca/refid19 2010-10-25T09:22:20Z

BACKGROUND: Milia en plaque (MEP) is an unusual entity with a distinctive clinicohistologic appearance. Optimal treatment is unestablished, particularly for MEP located on difficult anatomic areas. OBJECTIVE: To illustrate by a case report the clinical presentation and management of MEP. METHODS: A 35-year-old woman with numerous tiny cysts within an slightly erythematous base in unilateral perior...<br/><br/>Maria P Stefanidou, John G Panayotides, Androniki D Tosca (2002) <i>Dermatol Surg</i> <i></i> <i></i> 28: 3 291-295<br/>

http://publicationslist.org/androniki.tosca/refid57 2010-10-25T09:22:20Z

M Stefanidou, D Ioannidou, A Tosca (2001) <i>Dermatology</i> <i></i> <i></i> 202: 3 270-271<br/>

http://publicationslist.org/androniki.tosca/refid22 2010-10-25T09:22:20Z

M P Stefanidou, P E Kanavaros, A D Tosca (2001) <i>Int J Dermatol</i> <i></i> <i></i> 40: 1 50-52<br/>

http://publicationslist.org/androniki.tosca/refid21 2010-10-25T09:22:20Z

D J Ioannidou, M P Stefanidou, J G Panayiotides, A D Tosca (2001) <i>Int J Dermatol</i> <i></i> <i></i> 40: 1 54-57<br/>

http://publicationslist.org/androniki.tosca/refid20 2010-10-25T09:22:20Z

Human papilloma virus infection is increasing at an alarming rate. The ability of the virus to establish a subclinical infection and its association with malignancy of the lower genital tract make the statistics even more worrisome. Topical application of acetic acid solution provokes temporal alterations of the light-scattering properties of human papilloma virus-induced lesions of anogenital are...<br/><br/>I M Stefanaki, A D Tosca, G C Themelis, E M Vazgiouraki, D N Dokianakis, J G Panayiotidis, D A Spandidos, C J Balas (2001) <i>J Photochem Photobiol B</i> <i></i> <i></i> 65: 2-3 115-121<br/>

http://publicationslist.org/androniki.tosca/refid23 2010-10-25T09:22:20Z

A 78-year-old farmer presented with symptomless skin lesions for evaluation. Two years prior, he had developed idiopathic pulmonary fibrosis (IPF) and had been treated thereafter with oral prednisolone 20 mg/day and occasionally with colchicine 1 mg/day. On examination, erythematoviolaceous, slightly infiltrated plaques, measuring approximately 5 x 9 cm, rubbery in consistency, intermingled with p...<br/><br/>D J Ioannidou, M P Stefanidou, S G Maraki, J G Panayiotides, A D Tosca (2000) <i>Int J Dermatol</i> <i></i> <i></i> 39: 4 293-295<br/>

http://publicationslist.org/androniki.tosca/refid58 2010-10-25T09:22:20Z

Photodynamic therapy (PDT) with topical d-aminolevulinic acid (ALA) has become a therapeutic option of growing interest for superficial non-melanoma precancerous and malignant lesions. After application of ALA, in situ conversion to endogenous porphyrins is accomplished in a gradual manner. Therefore, the determination of fluorescence kinetics and spatial distribution in vivo versus time is a cruc...<br/><br/>M Stefanidou, A Tosca, G Themelis, E Vazgiouraki, C Balas (2000) <i>Eur J Dermatol</i> <i></i> <i></i> 10: 5 351-356<br/>

http://publicationslist.org/androniki.tosca/refid24 2010-10-25T09:22:20Z

BACKGROUND: Few studies of prospectively collected data regarding the natural course of bullous pemphigoid have been performed. METHODS: The following factors were combined both quantitatively and qualitatively to obtain results: gender, clinical activity based on the estimation of the body area involvement, disease duration, relapses, coexistence with other disease states, and serology Twenty-sev...<br/><br/>K P Kyriakis, V A Paparizos, D N Panteleos, A D Tosca (1999) <i>Int J Dermatol</i> <i></i> <i></i> 38: 12 909-913<br/>

http://publicationslist.org/androniki.tosca/refid26 2010-10-25T09:22:20Z

In this article we present a method for the objective assessment and monitoring of tissue blood supply using a specially developed endoscopic imaging colorimeter that enables quantitative color modeling of the back-scattered light during endoscopic examination. Tissue blood volume changes in the nasal mucosa, induced by xylometazoline hydrochloride nasal spray, were evaluated with this method. It ...<br/><br/>E P Prokopakis, C J Balas, P N Christodoulou, N C Gourtsoyiannis, A D Tosca, E S Helidonis (1999) <i>Otolaryngol Head Neck Surg</i> <i></i> <i></i> 121: 3 307-312<br/>

http://publicationslist.org/androniki.tosca/refid25 2010-10-25T09:22:20Z

Heparin analogues in low doses have antiproliferative and immunomodulatory properties. The aim of this study was to evaluate the effect of low-dose enoxaparin administered subcutaneously in lichen planus (LP). Eighteen patients with various types of LP were treated in an open study for 6-13 weeks. Efficacy and safety data were recorded. Complete remission was observed in 11 of 18 patients (61%) an...<br/><br/>M P Stefanidou, D J Ioannidou, J G Panayiotides, A D Tosca (1999) <i>Br J Dermatol</i> <i></i> <i></i> 141: 6 1040-1045<br/>

http://publicationslist.org/androniki.tosca/refid27 2010-10-25T09:22:20Z

Amicrobial pustulosis (AP) is a recently defined entity associated with connective tissue diseases. Few cases have appeared in the literature. We report a case of AP coexisting with a systemic lupus erythematosus-scleroderma overlap syndrome and marked photosensitivity. The patient presented prominent pustular skin lesions and a few discoid lupus ones. No significant differences in the inflammator...<br/><br/>M P Stefanidou, P E Kanavaros, K S Stefanaki, A D Tosca (1998) <i>Dermatology</i> <i></i> <i></i> 197: 4 394-396<br/>

http://publicationslist.org/androniki.tosca/refid28 2010-10-25T09:22:20Z

BACKGROUND: During the last 20 years, few prospective studies on the natural course of pemphigus vulgaris (PV) have been performed. METHODS: Various correlations of disease duration, clinical activity fluctuations, serology, and coexistence with other disease states were analyzed with regard to their impact upon the natural history of pemphigus. Thirty-seven consecutive PV patients were involved i...<br/><br/>K P Kyriakis, A D Tosca (1998) <i>Int J Dermatol</i> <i></i> <i></i> 37: 3 215-219<br/>

http://publicationslist.org/androniki.tosca/refid121 2010-10-25T12:46:40Z

Tosca AD. (1997) <i>J Eur Acad Dermatol & Venereol. </i> 9: 100-101<br/>

http://publicationslist.org/androniki.tosca/refid120 2010-10-25T12:45:33Z

Stiakaki E, Kalmanti M, Tosca A, Pakitzaki E, Melidoni M, Stournaras C. (1996) <i>Chimika Chronika </i> 25(3): 117<br/>

http://publicationslist.org/androniki.tosca/refid119 2010-10-25T12:44:38Z

Tosca AD, Nicolaidou A, Kyriakis KP. (1996) <i>Skin Cancer </i> 11: 121-132<br/>

http://publicationslist.org/androniki.tosca/refid115 2010-10-25T12:07:34Z

Tosca AD, Ioannidou DJ, Katsantonis JC, Kyriakis KP. (1996) <i>Eur J Acad Dermatol & Venereol</i> 6: 135-141<br/>

http://publicationslist.org/androniki.tosca/refid59 2010-10-25T09:22:20Z

BACKGROUND: The finite element analysis (FEA) is a recently introduced method in biomechanics that permits modeling of complex structures considering them as an aggregate of small elements. Skin flaps are highly suggested to be amenable to the continuum mechanic laws that underly the development of FEA. OBJECTIVE: A combination of "large deformation analysis," based on FEA with the criteria for sk...<br/><br/>A Manios, J Katsantonis, A Tosca, C H Skulakis, D Tsiftsis (1996) <i>Dermatol Surg</i> <i></i> <i></i> 22: 12 1029-1033<br/>

http://publicationslist.org/androniki.tosca/refid29 2010-10-25T09:22:20Z

BACKGROUND: Photodynamic therapy with delta-aminolevulinic acid is a promising alternative treatment for superficial skin malignancies. OBJECTIVE: Further clinical experience, study of tissue alterations leading to recovery, and correlation/prediction of the therapeutic response through in vivo skin color changes as represented by erythema development. METHODS: The therapeutic procedure, sequentia...<br/><br/>A D Tosca, C J Balas, M P Stefanidou, J C Katsantonis, S K Georgiou, M N Tzardi (1996) <i>Dermatol Surg</i> <i></i> <i></i> 22: 11 929-934<br/>

http://publicationslist.org/androniki.tosca/refid30 2010-10-25T09:22:20Z

BACKGROUND AND DESIGN: Sunlight and air temperature are environmental parameters with considerable influence upon autoimmunity. Their impact on idiopathic bullous pemphigoid (BP) was studied 1) in a prospective series of 27 patients with regard to clinical activity and 2) in a retrospective series of 232 cases during a 7-year period with regard to immunoserology. RESULTS: Skin involvement and the ...<br/><br/>K S Kyriakis, D N Panteleos, A D Tosca (1996) <i>Int J Dermatol</i> <i></i> <i></i> 35: 7 498-501<br/>

http://publicationslist.org/androniki.tosca/refid118 2010-10-25T12:42:56Z

Lotti T, Tosca A. (1995) <i>Editorial Int Angiology Guest Editor</i> 14: 99-100<br/>

http://publicationslist.org/androniki.tosca/refid31 2010-10-25T09:22:20Z

In 30 male patients suffering from recurrent condylomata acuminata, immediate hypersensitivity parameters (total IgE, PTT and prick tests) and delayed hypersensitivity against seven recall antigens (multi test) were studied. Thirty healthy male volunteers, matched in age, were the controls. Significantly higher immediate hypersensitivity activity was shown in the patient group. Qualitative evaluat...<br/><br/>K P Kyriakis, A K Balamotis, A Katsarou-Katsari, A D Tosca (1995) <i>Eur J Clin Invest</i> <i></i> <i></i> 25: 12 906-909<br/>

http://publicationslist.org/androniki.tosca/refid32 2010-10-25T09:22:20Z

BACKGROUND: Histoid leprosy is a rare form of multibacillary leprosy as the result of secondary or even primary resistance to dapsone. The etiopathogenesis has not been clarified up to now. METHODS: An immunohistochemical study was carried out for the expression of various markers on epidermal and dermal cell populations using sections of frozen skin specimens from 5 patients with histoid leprosy ...<br/><br/>G J Kontochristopoulos, K Aroni, D N Panteleos, A D Tosca (1995) <i>Int J Dermatol</i> <i></i> <i></i> 34: 11 777-781<br/>

http://publicationslist.org/androniki.tosca/refid33 2010-10-25T09:22:20Z

BACKGROUND: Pemphigus vulgaris is an autoimmune disorder, in which environmental factors seem to play a role, both in the pathogenesis and the activity of the disease. The purpose of the study was to correlate the biologic activity of pemphigus vulgaris with sun exposure and air temperature. METHODS: An epidemiologic study was carried out, analyzing results of serology, skin involvement, and propo...<br/><br/>K P Kyriakis, A G Vareltzidis, A D Tosca (1995) <i>Int J Dermatol</i> <i></i> <i></i> 34: 3 181-185<br/>

http://publicationslist.org/androniki.tosca/refid60 2010-10-25T09:22:20Z

E Mamalaki, J Katsantonis, S Papavasiliou, P Avgoustinaki, I Petrogiannaki, M Tzardis, M Tabakaki, A Tosca (1995) <i>J Am Acad Dermatol</i> <i></i> <i></i> 32: 1 130-133<br/>

http://publicationslist.org/androniki.tosca/refid116 2010-10-25T12:40:19Z

Stefanidou M, Nikiforos A, Georgiou S, Datseris G, Katsantonis J, Tosca A. (1995) <i>J Eur Acad Dermatol & Venereol. </i> 5: 129-129<br/>

http://publicationslist.org/androniki.tosca/refid117 2010-10-25T12:41:26Z

Tosca AD. (1995) <i>J Eur Acad Dermatol & Venereol. </i> 5: S60<br/>

http://publicationslist.org/androniki.tosca/refid61 2010-10-25T09:22:20Z

The state of polymerization of actin and the organization of actin filaments is widely believed to be related to cellular transformation. Since the intracellular monomer (G) and filamentous (F) actin content reflects the state of microfilament polymerization, we measured the G/total actin ratio in primary cultures of normal and malignant human keratinocytes. In normal keratinocytes the mean value ...<br/><br/>J Katsantonis, A Tosca, S B Koukouritaki, P A Theodoropoulos, A Gravanis, C Stournaras (1994) <i>Cell Biochem Funct</i> <i></i> <i></i> 12: 4 267-274<br/>

http://publicationslist.org/androniki.tosca/refid64 2010-10-25T09:22:20Z

Physical properties of hematoporphyrin-enriched collagen gels relevant to the photodynamic treatment of cancer are characterized. The incorporation of the sensitizer within the gels does not affect either the structure of the gel or the absorption and fluorescence spectra of the sensitizer. The gel-embedded sensitizer photodegrades efficiently with the formation of a product emitting near 635 nm. ...<br/><br/>S Georgiou, T Papazoglou, D Dafnomili, A G Coutsolelos, V Kouklaki, A Tosca (1994) <i>J Photochem Photobiol B</i> <i></i> <i></i> 22: 1 45-50<br/>

http://publicationslist.org/androniki.tosca/refid114 2010-10-25T12:05:52Z

Katsantonis JC, Vlachonicolis IG, Papavasiliou E, Tosca AD. (1994) <i>J Eur Acad Dermatol. </i> 3: 490-494<br/>

http://publicationslist.org/androniki.tosca/refid62 2010-10-25T09:22:20Z

The expression of C-myc p62, bcl-2, p53, PCNA and EBV-encoded LMP-1 proteins was studied by immunohistochemistry on paraffin-embedded skin specimens from 14 patients with early stage (premycotic erythema and second stage plaques) mycosis fungoides (MF), 21 patients with advanced stage MF (third stage plaques and tumors), 3 patients with Sezary's syndrome (SS) and 3 patients with pleomorphic medium...<br/><br/>P Kanavaros, D Ioannidou, M Tzardi, G Datseris, J Katsantonis, G Delidis, A Tosca (1994) <i>Pathol Res Pract</i> <i></i> <i></i> 190: 8 767-774<br/>

http://publicationslist.org/androniki.tosca/refid113 2010-10-25T12:02:21Z

Avgerinous G, Asvesti C, Sikiotis K, Konti-Pafiti A, Nicolaidou A, Tosca A. (1994) <i>Les Nouvelles Dermatologiques </i> 12: 306-308<br/>

http://publicationslist.org/androniki.tosca/refid112 2010-10-25T12:01:08Z

Kroumpouzos G, Tosca A, Konstadoulakis M, Avgerinou G, Varelzidis A, Stratigos J. (1994) <i>J Eur Acad Dermatol & Venereol. </i> 3: 140-147<br/>

http://publicationslist.org/androniki.tosca/refid63 2010-10-25T09:22:20Z

DNA samples from recurrent condylomata acuminata biopsies of Greek males and females were examined for the presence of human papillomavirus (HPV) DNA using high-stringency Southern blot hybridization analysis. Of the twenty-six biopsies, 25 were positive for the HPV 6/11-related DNA sequences, and when further analyzed with the polymerase chain reaction (PCR) the HPV-negative biopsy was also posit...<br/><br/>V Labropoulou, A Balamotis, A Tosca, A Rotola, P Mavromara-Nazos (1994) <i>J Med Virol</i> <i></i> <i></i> 42: 3 259-263<br/>

http://publicationslist.org/androniki.tosca/refid111 2010-10-25T11:58:36Z

Hatzis J, Kyriakis K, Tzouvelekis L, Zhai HB, Tosca A. (1993) <i>Eur J Dermatol. </i> 3: 491-494<br/>

http://publicationslist.org/androniki.tosca/refid67 2010-10-25T09:22:20Z

Thirty four sera from: 12 patients with Systemic Lupus Erythematosus (SLE), 9 with Subacute Cutaneous Lupus Erythematosus (SCLE) and 13 with Discoid Lupus Erythematosus (DLE) (disseminatus 3, localised 10) were tested for the presence of: (a) anti-thyroglobulin and anti-microsomal autoantibodies (b) anti-Sm/RNP, anti-doublestranded. DNA (anti-ds. DNA), anti-single-Stranded. DNA (anti-ss. DNA), ant...<br/><br/>M M Konstadoulakis, G Kroubouzos, A Tosca, G Piperingos, P Marafelia, M Konstadoulakis, A Varelzidis, D A Koutras (1993) <i>Thyroidology</i> <i></i> <i></i> 5: 1 1-7<br/>

http://publicationslist.org/androniki.tosca/refid65 2010-10-25T09:22:20Z

Immunological responses to a panel of antigens were evaluated in 27 patients with lepromatous and 20 patients with tuberculoid leprosy and compared with 24 pulmonary tuberculosis patients, 25 systemic lupus erythematosus patients and 41 healthy blood donors. Some autoantibody specificities were extensively studied for the first time in mycobacterial infections. Striking immunoserological abnormali...<br/><br/>G Kroumpouzos, A Vareltzidis, M M Konstadoulakis, G Avgerinou, G Anastasiadis, H Kroubouzou, A Panteleos, A Tosca (1993) <i>Lepr Rev</i> <i></i> <i></i> 64: 3 199-207<br/>

http://publicationslist.org/androniki.tosca/refid66 2010-10-25T09:22:20Z

The serum levels of soluble interleukin 2 receptor (SIL-2R) and tumor necrosis factor (TNF) were assessed in 69 children from 6 months to 14 years old who suffered from acute lymphoblastic leukemia (39), Hodgkin's disease (15), non-Hodgkin's lymphoma (15) and in 54 normal age-matched controls prior to any therapy and at remission. Both SIL-2R and TNF levels were significantly higher at diagnosis c...<br/><br/>M Kalmanti, K Karamolengou, H Dimitriou, A Tosca, I Vlachonikolis, M Peraki, V Georgoulias, T Kalmantis (1993) <i>Int J Hematol</i> <i></i> <i></i> 57: 2 147-152<br/>

http://publicationslist.org/androniki.tosca/refid110 2010-10-25T11:55:25Z

Tosca AD, Stratigos JD. (1992) <i>J Eur Acad Derm. Vener. </i> 1: 179-186<br/>

http://publicationslist.org/androniki.tosca/refid68 2010-10-25T09:22:20Z

G Kroubouzos, A Tosca, M M Konstadoulakis, A Varelzidis (1992) <i>J Immunol Methods</i> <i></i> <i></i> 148: 1-2 261-263<br/>

http://publicationslist.org/androniki.tosca/refid69 2010-10-25T09:22:20Z

We have examined various autoimmunity parameters in AIDS with special emphasis on the expression of pemphigus and bullous pemphigoid antibodies. Sera from healthy seropositive individuals without syphilis (CS-, n = 17), seropositive individuals with syphilis (cs+, n = 11), and patients with AIDS (n = 6) were studied and compared with normal controls (n = 30); autoimmunity parameters related to der...<br/><br/>K Kyriakis, A Tosca, J Katsantonis, M Hatzivasiliou, G Eliopoulos, J Stratigos (1992) <i>Int J Dermatol</i> <i></i> <i></i> 31: 2 113-116<br/>

http://publicationslist.org/androniki.tosca/refid72 2010-10-25T09:22:20Z

A 53-year-old female patient with pemphigus vulgaris under continuous immunosuppressive therapy for about 2 years presented a superficial spreading malignant melanoma on a pre-existing melanocytic naevus. After surgical removal of the inguinal lymph node group, a diffuse low-grade polymorphous immunocytoma was proved both histologically and immunocytochemically. The possible induction mechanisms a...<br/><br/>K Kyriakis, P Stavropoulos, E Hatziolou, G Dellidis, A Varelzidis, A Tosca (1991) <i>Dermatologica</i> <i></i> <i></i> 183: 1 49-52<br/>

http://publicationslist.org/androniki.tosca/refid71 2010-10-25T09:22:20Z

In the present work, we have attempted to pay special attention to epidermal and dermal cellular events in Mycosis fungoides (MF). In the epidermis, the two dendritic cell populations, CD1+ and OKM5+, HLe-1+, the adhesion molecules OKM5 and DR on the surface of epidermal cells (Ecs), and cytoskeletal proteins were studied. CD1+ dendritic epidermal cells were generally more abundant than OKM5+, HLe...<br/><br/>A Tosca, A Ifantis, M Kalmanti, A Panagiotopoulos, J Stratigos (1991) <i>J Dermatol</i> <i></i> <i></i> 18: 3 152-160<br/>

http://publicationslist.org/androniki.tosca/refid70 2010-10-25T09:22:20Z

In the present work, we studied the expression of the c-myc oncoprotein p-62 and the ras oncoprotein p-21 in the dermal cellular infiltrate of paraffin embedded skin specimens, obtained from patients suffering from Mycosis Fungoides and Sezary syndrome. Nineteen specimens from early stage Mycosis Fungoides, nineteen from advanced stage Mycosis Fungoides and four from Sezary syndrome were included ...<br/><br/>A Tosca, S Linardopoulos, A Malliri, E Hatziolou, A Nicolaidou, D A Spandidos (1991) <i>Anticancer Res</i> <i></i> <i></i> 11: 4 1433-1438<br/>

http://publicationslist.org/androniki.tosca/refid73 2010-10-25T09:22:20Z

A Tosca, P G Stavropoulos, E Hatziolou, A Arvanitis, N Stavrianeas, M Hatzivassiliou, J D Stratigos (1990) <i>Int J Dermatol</i> <i></i> <i></i> 29: 8 575-578<br/>

http://publicationslist.org/androniki.tosca/refid75 2010-10-25T09:22:20Z

In a five year period 73 cases of pemphigus vulgaris (PV) and 94 of bullous pemphigoid (BP) were studied to investigate important parameters for these diseases. From the results it was found that the incidence of PV was higher in women whereas that of BP was almost equal in both sexes. The incidence of PV was highest in the sixth decade but was highest in the eighth decade for BP. Indirect immunof...<br/><br/>K Kyriakis, A Tosca, J Lehou, J Hatzis, A Vareltzidis, J Stratigos (1989) <i>Australas J Dermatol</i> <i></i> <i></i> 30: 1 33-36<br/>

http://publicationslist.org/androniki.tosca/refid74 2010-10-25T09:22:20Z

J Hatzis, P Kostakis, A Tosca, N Parissis, G Nicolis, A Varelzidis, J Stratigos (1989) <i>Dermatologica</i> <i></i> <i></i> 179: 4 <br/>

http://publicationslist.org/androniki.tosca/refid109 2010-10-25T11:53:42Z

Tosca A, Stratigos J. (1989) <i>Int J Dermatol. </i> 2: 291-298<br/>

http://publicationslist.org/androniki.tosca/refid108 2010-10-25T11:52:13Z

Hatzis J, Gourgiotou K, Tosca A, Varelzidis A, Stratigos J. (1989) <i>Dermatologica</i> 179: 137-138<br/>

http://publicationslist.org/androniki.tosca/refid106 2010-10-25T11:47:17Z

Hatzis J, Danopoulou I, Tosca A, Stratigos J. (1988) <i>Bioeng. Skin </i> 4: 53-65<br/>

http://publicationslist.org/androniki.tosca/refid107 2010-10-25T11:48:53Z

Goumas P, Tosca N, Tromboukis D., Sissis Th. (1988) <i>Laryng. Rhinol. Otol. </i> 67: 34-37<br/>

http://publicationslist.org/androniki.tosca/refid79 2010-10-25T09:22:20Z

In this work, the incidence of nuchal nevus flammeus was studied in 205 patients suffering from various forms of alopecia areata, as well as in a group of 555 volunteers without alopecia areata examined in our outpatient clinic. The incidence of nuchal nevus flammeus in the totalis-universalis form of alopecia areata was 58.2% (examined patients, n = 79), in ophiasis-extensive forms 22.8% (examine...<br/><br/>J Hatzis, P Kostakis, A Tosca, N Parissis, G Nicolis, A Varelzidis, J Stratigos (1988) <i>Dermatologica</i> <i></i> <i></i> 177: 3 149-151<br/>

http://publicationslist.org/androniki.tosca/refid78 2010-10-25T09:22:20Z

J Hatzis, K Georgiotouo, P Kostakis, G Anastasiadis, A Tosca, A Varelzidis, J Straigos (1988) <i>Australas J Dermatol</i> <i></i> <i></i> 29: 1 33-36<br/>

http://publicationslist.org/androniki.tosca/refid125 2010-10-25T13:03:57Z

Tosca A, Panagiotopoulos A, Stavrakakis M, Hatzis J, Vareltzidis A, Stratigos J. (1988) <i>Skin Cancer </i> 3: 85-89<br/>

http://publicationslist.org/androniki.tosca/refid77 2010-10-25T09:22:20Z

Fourteen patients with allergic cutaneous vasculitis of either the polymorphonuclear (PMN)- or the mononuclear (MN)-predominant type were studied as regards the following parameters: the disease duration, histology, monoclonal antibody typing of the mononuclear cell infiltrate from recent lesions, and the delayed hypersensitivity (DH) response, assessed both by recall antigens (tuberculin type) an...<br/><br/>A Tosca, J Hatzis, K Kyriakis, P Stavropoulos, A Varelzidis, J Stratigos (1988) <i>Angiology</i> <i></i> <i></i> 39: 4 360-364<br/>

http://publicationslist.org/androniki.tosca/refid76 2010-10-25T09:22:20Z

An immunohistological study of skin biopsy specimens from patients with early syphilis was undertaken before and after treatment (one day after intramuscular administration of 2.4 MIU benzathine penicillin and eight days later, after a total administration of 3.6 MIU. In chancres from seronegative patients treatment with 3.6 MIU usually resulted in fewer immunocompetent cells in the infiltrate. In...<br/><br/>A Tosca, J Lehou, M Hatjivasiliou, A Varelzidis, J D Stratigos (1988) <i>Genitourin Med</i> <i></i> <i></i> 64: 5 289-293<br/>

http://publicationslist.org/androniki.tosca/refid126 2010-10-25T13:05:25Z

Tosca A., Stratigos JD. (1988) <i> Int J Dermatol</i> 27: 291-296<br/>

http://publicationslist.org/androniki.tosca/refid80 2010-10-25T09:22:20Z

During the topical treatment of 45 patients, who had extensive forms of alopecia areata, with the allergen diphencyprone, 3 of them (6.7%) developed vitiligo. Two were females and 1 male aged 53, 19 and 28 years respectively. None of these patients had a personal or family history of vitiligo. Vitiligo appeared 3-5 months after the onset of treatment and was localized only to the areas of topical ...<br/><br/>J Hatzis, K Gourgiotou, A Tosca, A Varelzidis, J Stratigos (1988) <i>Dermatologica</i> <i></i> <i></i> 177: 3 146-148<br/>

http://publicationslist.org/androniki.tosca/refid81 2010-10-25T09:22:20Z

J Hatzis, A Tosca, A Varelzidis, J Stratigos (1987) <i>Br J Dermatol</i> <i></i> <i></i> 117: 6 797-798<br/>

http://publicationslist.org/androniki.tosca/refid82 2010-10-25T09:22:20Z

We have shown that skin surface marking exists on the prickle cell layer after provocation of intra-epidermal vesiculation with a 50% solution of NH4OH.<br/><br/>J Hatzis, A Tosca, A Varelzidis, J Stratigos (1987) <i>Br J Dermatol</i> <i></i> <i></i> 116: 4 497-501<br/>

http://publicationslist.org/androniki.tosca/refid34 2010-10-25T09:22:20Z

A D Tosca, N C Babanioti, A C Panagiotopoulos, J D Hatzis, A G Varelzidis, J D Stratigos (1987) <i>Australas J Dermatol</i> <i></i> <i></i> 28: 3 129-131<br/>

http://publicationslist.org/androniki.tosca/refid36 2010-10-25T09:22:20Z

Lesional skin specimens from twenty-eight patients with mycosis fungoides were studied by evaluating immunohistochemical criteria, primarily with monoclonal antibodies. It was demonstrated that significant differences exist between the control and the premycotic-stage group in regard to the monoclonal antibodies BE1, BE2, and OKT9. The detection of specific antigenic determinants on the surface of...<br/><br/>A D Tosca, A G Varelzidis, J Economidou, J D Stratigos (1986) <i>J Am Acad Dermatol</i> <i></i> <i></i> 15: 2 Pt 1 237-245<br/>

http://publicationslist.org/androniki.tosca/refid35 2010-10-25T09:22:20Z

A D Tosca, J Lehou, A Panagiotopoulos, A Varelzidis, J Stratigos (1986) <i>J Dermatol</i> <i></i> <i></i> 13: 5 366-371<br/>

http://publicationslist.org/androniki.tosca/refid105 2010-10-25T11:45:08Z

Tosca A, Panteleos D, Varelzidis A, Stratigos J. (1986) <i>Skin cancer </i> 2: 117-129<br/>

http://publicationslist.org/androniki.tosca/refid85 2010-10-25T09:22:20Z

Two further methods for the characterization of epidermal skin tumors are described: the antinuclear antibody (ANA) immunofluorescent test, which consists of indirect immunofluorescence with known high titer sera containing homogenous ANAs on epidermal skin tumors, and the ammoniacal-silver cytochemical method, which specifically stains nuclear histones. Squamous cell carcinomas (SCCs), basal cell...<br/><br/>A Tosca, A Varelzidis, K Bassioukas, J Hatzis, G Nicolis, J Stratigos (1985) <i>Dermatologica</i> <i></i> <i></i> 171: 1 21-26<br/>

http://publicationslist.org/androniki.tosca/refid84 2010-10-25T09:22:20Z

Peripheral blood lymphocytes from 21 patients with aleukaemic stages of mycosis fungoides were studied with monoclonal T cell antibodies. Patients with erythematous eruptions or infiltrated plaques (group I) had a higher percentage of OKT4+ cells than patients with a tumorous stage (group II) or normal subjects (p = 0.05). OKT8+ cells were decreased in group I patients whereas in group II they wer...<br/><br/>J Economidou, H Choremi, A Kofina, A Tosca, P Kotsakis, A Vareldzidis, J Stratigos (1985) <i>Dermatologica</i> <i></i> <i></i> 170: 2 59-64<br/>

http://publicationslist.org/androniki.tosca/refid83 2010-10-25T09:22:20Z

A Tosca, J Hatzis, D Panteleos, A Varelzidis (1985) <i>J Dermatol</i> <i></i> <i></i> 12: 3 226-231<br/>

http://publicationslist.org/androniki.tosca/refid86 2010-10-25T09:22:20Z

A Tosca, A Varelzidis, H Kavadda, M Michalopoulos, J Hatzis, J Stratigos (1984) <i>J Dermatol</i> <i></i> <i></i> 11: 4 354-360<br/>

http://publicationslist.org/androniki.tosca/refid88 2010-10-25T09:22:20Z

In this study, the in situ immunological typing of cell populations in lichen planus was attempted. T lymphocytes and suppressor/cytotoxic subsets, B lymphocytes, macrophages, immunocytes and Langerhans' cells were studied by one or more technical parameters and semiquantitative assessment of T cell populations were carried out. A critical evaluation of assays for T cell characterization was also ...<br/><br/>A Tosca, A Varelzidis, M Michalopoulos, S Georgala, J Stratigos (1983) <i>Dermatologica</i> <i></i> <i></i> 167: 3 113-120<br/>

http://publicationslist.org/androniki.tosca/refid87 2010-10-25T09:22:20Z

We studied sweat gland distribution, density and activity in thirteen cases of granuloma annulare and ten cases of necrobiosis lipoidica, using a combination of the plastic impression and starch-iodine methods. The pattern of sweat gland disturbance in the two diseases was entirely different. In necrobiosis lipoidica an intense and uniform hypohidrosis was detected throughout the lesion, whereas i...<br/><br/>J Hatzis, A Varelzidis, A Tosca, J Stratigos (1983) <i>Br J Dermatol</i> <i></i> <i></i> 108: 6 705-709<br/>

http://publicationslist.org/androniki.tosca/refid89 2010-10-25T09:22:20Z

In 54 cases of dermatophytosis, sweat gland disturbances and their possible mechanisms were studied. The basic perspiratory malfunction was intense hypohidrosis, with some hyperhidrotic phenomena being observed at particular points of the exanthem (margin and disc) in a few cases. It is worth noting that in 51.85% of the cases, hypohidrotic phenomena were also observed in areas of normal skin adja...<br/><br/>J Hatzis, A Varelzidis, A Tosca, J Stratigos, J Capetanakis (1982) <i>Arch Dermatol Res</i> <i></i> <i></i> 273: 1-2 1-7<br/>

http://publicationslist.org/androniki.tosca/refid90 2010-10-25T09:22:20Z

In 2 patients with anhidrotic ectodermal dysplasia, we were able to show that the hypoplastic eccrine glandular elements may give rise to normal eccrine glands both anatomically and functionally, after repeated local application of acetylcholine. The perspectives of our findings for the therapeutic management of the anhidrotic ectodermal dysplasia are discussed and special attention is paid to the...<br/><br/>J Hatzis, A Tosca, K Moulopoulou-Karakitsou, J Stratigos, A Varelzidis, J Capetanakis (1982) <i>Dermatologica</i> <i></i> <i></i> 164: 1 54-61<br/>

http://publicationslist.org/androniki.tosca/refid104 2010-10-25T11:42:52Z

Tosca AD, Parker D, Turk JL. (1981) <i>Cellular Immunology </i> 62: 28-37<br/>

http://publicationslist.org/androniki.tosca/refid91 2010-10-25T09:22:20Z

The present study deals with the evaluation of some substrates for the detection of nuclear antibodies by the indirect immunofluorescence method. We have examined white male mouse liver imprint, white female pregnant mouse liver imprint, compound substrate consisting of male mouse liver, kidney and gastric wall sections, skin sections from psoriatic patients, skin sections from squamous cell carci...<br/><br/>A Tosca, J Hatzis, A Haidas, A Varelzidis (1981) <i>Dermatologica</i> <i></i> <i></i> 163: 5 401-407<br/>

http://publicationslist.org/androniki.tosca/refid92 2010-10-25T09:22:20Z

A Tosca, Z Chrisoboli, J Hatzis, A Varelzidis, J Stratigos (1981) <i>Arch Dermatol Res</i> <i></i> <i></i> 271: 3 351-356<br/>

http://publicationslist.org/androniki.tosca/refid103 2010-10-25T11:41:21Z

Vella Briffa D, Parker D, Tosca AD, Turk JL, Greaves MW. (1981) <i>The J Invest Dermatol.</i> 77: 377-380<br/>

http://publicationslist.org/androniki.tosca/refid95 2010-10-25T09:22:20Z

A case of local hyperhidrosis at the ulnar aspect of the left forearm-carpal region with exacerbation, especially during summer, is presented. The sweat function is normal on the remainder of the body. This case is rare, and few similar cases are known in the literature. The possible pathogenetic mechanisms are discussed.<br/><br/>J Hatzis, C Papaioannou, A Tosca, A Varelzidis, J Capetanakis (1980) <i>Dermatologica</i> <i></i> <i></i> 161: 1 45-50<br/>

http://publicationslist.org/androniki.tosca/refid94 2010-10-25T09:22:20Z

Cutaneous leishmaniasis is a disease endemic in Greece. Cases collected between the years 1975 and 1979 are analyzed from a clinico-epidemiologic point of view. Prevalence is highest in the Ionian islands and Crete. The disease most commonly affects individuals 10 to 20 years of age. The exposed parts of the body are most commonly involved, particularly the face. The period of highest incidence is...<br/><br/>J Stratigos, A Tosca, G Nicolis, S Papavasiliou, J Capetanakis (1980) <i>Int J Dermatol</i> <i></i> <i></i> 19: 2 86-88<br/>

http://publicationslist.org/androniki.tosca/refid93 2010-10-25T09:22:20Z

One hundred tumors of epidermal origin were studied by means of indirect immunofluorescence technique with sera from patients with proven pemphigus and bullous pemphigoid. We found that in tumors of epidermal origin, there was a loss of antigenicity of the intercellular substance and basement membrane; this was minimal for benign tumors, greater for premalignant tumors, and very clear for maligna...<br/><br/>A Tosca, A Varelzidis, G Nicolis, J Hadzis, J Stratigos, J Capetanakis (1980) <i>Cancer</i> <i></i> <i></i> 45: 9 2284-2290<br/>

http://publicationslist.org/androniki.tosca/refid97 2010-10-25T09:22:20Z

In the present study, the development of pemphigus and bullous pemphigoid antigens was investigated by means of the indirect immunofluorescence technique using sera of pemphigus and bullous pemphigoid patients, respectively, on human foetus skin antigenic substrate. Seventy skin specimens from embryos of 9-38 weeks of gestation were studied. Both pemphigus and bullous pemphigoid antigens were obse...<br/><br/>A Varelzidis, A Tosca, E Coumantakis, G Nicolis, J Hatzis, S Papavasiliou, J Stratigos (1980) <i>Acta Derm Venereol</i> <i></i> <i></i> 60: 2 129-133<br/>

http://publicationslist.org/androniki.tosca/refid96 2010-10-25T09:22:20Z

Twelve patients with keratoacanthoma were studied to assess the role and importance of immunological factors in tumor regression. Direct immunofluorescence was determined with immunoglobulins, complement (C3), and fibrin to estimate the deposition of these factors in the lesion area. Indirect immunofluorescence was also undertaken using pemphigus and bullous pemphigoid sera against the keratoacant...<br/><br/>A Tosca, A Varelzidis, G Avgerinou, J Hatzis, A Perissios, G Nicolis (1980) <i>Arch Dermatol Res</i> <i></i> <i></i> 268: 2 149-155<br/>

http://publicationslist.org/androniki.tosca/refid37 2010-10-25T09:22:20Z

G D Nicolis, A D Tosca, J D Stratigos (1979) <i>Australas J Dermatol</i> <i></i> <i></i> 20: 2 93-94<br/>

http://publicationslist.org/androniki.tosca/refid38 2010-10-25T09:22:20Z

G D Nicolis, J D Stratigos, A D Tosca, J A Capetanakis (1979) <i>Acta Derm Venereol</i> <i></i> <i></i> 59: 1 80-82<br/>

http://publicationslist.org/androniki.tosca/refid98 2010-10-25T09:22:20Z

J Zervas, A Tosca, I Apostolakis, A Varelzidis (1979) <i>Br J Dermatol</i> <i></i> <i></i> 101: 3 357-358<br/>

http://publicationslist.org/androniki.tosca/refid100 2010-10-25T09:22:20Z

An immunohistochemical study has been undertaken on 25 biopsy specmens taken from lichen planus lesions, using antisera against human fibrin, immunoglobulins IgG, IgA, IgM and C3 (B1C/B1A) complement component. The findings of the present research are discussed and evaluated in relation to the problem of the etiopathogenesis of the disease.<br/><br/>A Varelzidis, A Tosca, A Perissios, J Capetanakis (1979) <i>Dermatologica</i> <i></i> <i></i> 159: 2 137-144<br/>

http://publicationslist.org/androniki.tosca/refid99 2010-10-25T09:22:20Z

A case is described with features both of Hailey-Hailey and Darier's disease in a male patient who presented skin lesions since he was 8 years old. The present case is discussed in relation to data obtained from the literature, and a differential diagnosis from Grover's disease is made.<br/><br/>G Nicolis, A Tosca, O Marouli, J Stratigos (1979) <i>Dermatologica</i> <i></i> <i></i> 159: 4 346-351<br/>

http://publicationslist.org/androniki.tosca/refid39 2010-10-25T09:22:20Z

Sixty-five cases of proved cutaneous Leishmaniasis have been studied on clinical, histological and laboratory grounds. A new histological classification is proposed and emphasis is given to specific histological changes and their correspondence to distinct clinical signs.<br/><br/>G D Nicolis, A D Tosca, J D Stratigos, J A Capetanakis (1978) <i>Acta Derm Venereol</i> <i></i> <i></i> 58: 6 521-525<br/>

http://publicationslist.org/androniki.tosca/refid102 2010-10-25T11:37:52Z

Balas P, Stratigos J, Tripolitis A, Tosca A, Kelaris G. (1977) <i>Folia Angiologica </i> : 241-243<br/>

http://publicationslist.org/androniki.tosca/refid101 2010-10-25T11:36:09Z

Stratigos J, Tzitzi K, Tosca A, Capetanakis J, Zissis NP (1976) <i>Current Tehrapeutic Research </i> 20: 24-31<br/>