http://publicationslist.org/data/christian.wunder/atom.xml Christian Wunderhttp://publicationslist.org/christian.wunder$basepathfavicon.icoRecent additions to Christian Wunder's PublicationsList.org pagehttp://publicationslist.org/publications.png2008-06-24T15:39:54Z http://publicationslist.org/christian.wunder/refid3 2008-06-24T15:39:06Z

BACKGROUND: Membrane-bound glucocorticoid receptors (mGCR) are up regulated on monocytes after in vitro stimulation and in patients with rheumatoid arthritis. Caveolin-1 is critical for the transport of plasma membrane oestrogen receptors to the cell surface. OBJECTIVES: To investigate the expression of mGCR in patients with systemic lupus erythematosus (SLE)-a disease with different aetiopathogen...<br/><br/>C M Spies, D H S Schaumann, T Berki, K Mayer, M Jakstadt, D Huscher, C Wunder, G-R Burmester, A Radbruch, R Lauster, A Scheffold, F Buttgereit (2006) <i>Ann Rheum Dis</i> <i></i> <i></i> 65: 9 1139-1146<br/>

http://publicationslist.org/christian.wunder/refid8 2008-06-24T15:39:24Z

O-Glycans of the human gastric mucosa show antimicrobial activity against the pathogenic bacterium Helicobacter pylori by inhibiting the bacterial cholesterol-alpha-glucosyltransferase (Kawakubo, M., Ito, Y., Okimura, Y., Kobayashi, M., Sakura, K., Kasama, S., Fukuda, M. N., Fukuda, M., Katsuyama, T., and Nakayama, J. (2004) Science 305, 1003-1006). This enzyme catalyzes the first step in the bios...<br/><br/>Anne-Helene Lebrun, Christian Wunder, Janosch Hildebrand, Yuri Churin, Ulrich Zähringer, Buko Lindner, Thomas F Meyer, Ernst Heinz, Dirk Warnecke (2006) <i>J Biol Chem</i> <i></i> <i></i> 281: 38 27765-27772<br/>

http://publicationslist.org/christian.wunder/refid6 2008-06-24T15:39:24Z

Correct localization and topology are crucial for the cellular function of a protein. To determine the topology of membrane proteins, a new technique, called the fluorescence protease protection (FPP) assay, can be applied. This assay uses the restricted proteolytic digestibility of GFP-tagged transmembrane proteins to indicate their intramembrane orientation. The sole requirements for FPP are the...<br/><br/>Holger Lorenz, Dale W Hailey, Christian Wunder, Jennifer Lippincott-Schwartz (2006) <i>Nat Protoc</i> <i></i> <i></i> 1: 1 276-279<br/>

http://publicationslist.org/christian.wunder/refid7 2008-06-24T15:39:24Z

Helicobacter pylori infection causes gastric pathology such as ulcer and carcinoma. Because H. pylori is auxotrophic for cholesterol, we have explored the assimilation of cholesterol by H. pylori in infection. Here we show that H. pylori follows a cholesterol gradient and extracts the lipid from plasma membranes of epithelial cells for subsequent glucosylation. Excessive cholesterol promotes phago...<br/><br/>Christian Wunder, Yuri Churin, Florian Winau, Dirk Warnecke, Michael Vieth, Buko Lindner, Ulrich Zähringer, Hans-Joachim Mollenkopf, Ernst Heinz, Thomas F Meyer (2006) <i>Nat Med</i> <i></i> <i></i> 12: 9 1030-1038<br/>

http://publicationslist.org/christian.wunder/refid4 2008-06-24T15:39:06Z

Ras proteins control the signalling pathways that are responsible for normal growth and malignant transformation. Raf protein kinases are direct Ras effector proteins that initiate the mitogen-activated protein kinase (MAPK) cascade, which mediates diverse biological functions such as cell growth, survival and differentiation. Here we show that prohibitin, a ubiquitously expressed and evolutionari...<br/><br/>Krishnaraj Rajalingam, Christian Wunder, Volker Brinkmann, Yuri Churin, Mirko Hekman, Claudia Sievers, Ulf R Rapp, Thomas Rudel (2005) <i>Nat Cell Biol</i> <i></i> <i></i> 7: 8 837-843<br/>

http://publicationslist.org/christian.wunder/refid1 2008-06-24T15:38:27Z

VEGF-A is a key regulator of inflammatory and tumor-associated angiogenesis. H. pylori plays a critical role in the pathogenesis of benign and malignant gastric diseases. It has been suggested that H. pylori infection is associated with activation of host angiogenesis, however, underlying mechanisms as well as angiogenic growth factors activated by the bacterium have not yet been identified. There...<br/><br/>Mathias Z Strowski, Thorsten Cramer, Georgia Schäfer, Stefan Jüttner, Anna Walduck, Ernestina Schipani, Wolfgang Kemmner, Silja Wessler, Christian Wunder, Matthias Weber, Thomas F Meyer, Bertram Wiedenmann, Thomas Jöns, Michael Naumann, Michael Höcker (2004) <i>FASEB J</i> <i></i> <i></i> 18: 1 218-220<br/>

http://publicationslist.org/christian.wunder/refid5 2008-06-24T15:39:06Z

The pathogenesis of Helicobacter pylori-associated disorders is strongly dependent on a specialized type IV secretion system (T4SS) encoded by the cag pathogenicity island (PAI). Cytotoxin-associated gene A (CagA) is the only known H. pylori protein translocated into the host cell followed by tyrosine phosphorylation through host protein kinases. H. pylori induces cellular processes which are eith...<br/><br/>Laila Al-Ghoul, Silja Wessler, Tanja Hundertmark, Sabine Krüger, Wolfgang Fischer, Christian Wunder, Rainer Haas, Albert Roessner, Michael Naumann (2004) <i>Biochem Biophys Res Commun</i> <i></i> <i></i> 322: 3 860-866<br/>

http://publicationslist.org/christian.wunder/refid2 2008-06-24T15:38:27Z

Cyclooxygenase-2 (COX-2) represents the inducible key enzyme of arachidonic acid metabolism and contributes to the pathogenesis of gastroduodenal ulcers and gastric cancer. Helicobacter pylori infection is associated with elevated gastric COX-2 levels, but the mechanisms underlying H. pylori-dependent cox-2 gene expression are unclear. H. pylori stimulated cox-2 mRNA and protein abundance in gastr...<br/><br/>Stefan Jüttner, Thorsten Cramer, Silja Wessler, Anna Walduck, Feng Gao, Frank Schmitz, Christian Wunder, Matthias Weber, Susan M Fischer, Wolfgang E Schmidt, Bertram Wiedenmann, Thomas F Meyer, Michael Naumann, Michael Höcker (2003) <i>Cell Microbiol</i> <i></i> <i></i> 5: 11 821-834<br/>