http://publicationslist.org/data/e.r.brown/atom.xml Euan Brownhttp://publicationslist.org/e.r.brown$basepathfavicon.icoRecent additions to Euan Brown's PublicationsList.org pagehttp://publicationslist.org/publications.png2008-02-04T08:16:02Z http://publicationslist.org/e.r.brown/refid9 2008-02-02T05:31:08Z

L- and D-aspartic acids (L-Asp and D-Asp) are present in the majority of nervous systems. In phylogeny, significant levels have been reported in mollusc brains, particularly cephalopods. To examine the role of L- and D-Asp on a cephalopod receptor, we studied ligand gating of a squid glutamate receptor (SqGluR) expressed in HEK 239 (human embryonic kidney) cells. Under voltage clamp, application o...<br/><br/>E R Brown, S Piscopo, J-T Chun, M Francone, I Mirabile, A D'Aniello (2007) <i>Amino Acids</i> <i></i> <i></i> 32: 1 53-57<br/>

http://publicationslist.org/e.r.brown/refid2 2008-02-01T17:17:34Z

The ascidian Ciona intestinalis is a useful model for the study of nervous system development and function. The larva of this animal represents a 'primitive' vertebrate form that contains only about 100 neurons in the CNS. Although embryos can be easily subjected to genetic manipulation, the nervous system cells are not easily accessible for neurophysiological study at the larval stage. To remedy ...<br/><br/>Laura Zanetti, Filomena Ristoratore, Maria Francone, Stefania Piscopo, Euan R Brown (2007) <i>J Neurosci Methods</i> <i></i> <i></i> 165: 2 191-197<br/>

http://publicationslist.org/e.r.brown/refid5 2008-02-02T05:27:33Z

Ammonium uptake into the cell is known to be mediated by ammonium transport (Amt) proteins, which are present in all domains of life. The physiological role of Amt proteins remains elusive; indeed, loss-of-function experiments suggested that Amt proteins do not play an essential role in bacteria, yeast, and plants. Here we show that the reverse holds true in the tunicate Ciona intestinalis. The ge...<br/><br/>Rita Marino, Daniela Melillo, Miriam Di Filippo, Atsuko Yamada, Maria Rosaria Pinto, Rosaria De Santis, Euan R Brown, Giorgio Matassi (2007) <i>J Comp Neurol</i> <i></i> <i></i> 503: 1 135-147<br/>

http://publicationslist.org/e.r.brown/refid1 2008-02-02T05:25:54Z

Synaptic transmission was examined in the plexiform zone of Octopus vulgaris optic lobes using field-potential recording from optic lobe slices. Stimulation of the optic nerve produced pre- and postsynaptic field potentials. Transmission was abolished in calcium-free seawater, L- glutamate or the AMPA/Kainate receptor blocker CNQX (EC(50), 40 microm), leaving an intact presynaptic field potential....<br/><br/>Stefania Piscopo, Francesco Moccia, Carlo Di Cristo, Luigi Caputi, Anna Di Cosmo, Euan R Brown (2007) <i>Eur J Neurosci</i> <i></i> <i></i> 26: 8 2196-2203<br/>

http://publicationslist.org/e.r.brown/refid10 2008-02-02T05:31:08Z

L- and D-aspartic acids (L-Asp and D-Asp) are present in the majority of nervous systems. In phylogeny, significant levels have been reported in mollusc brains, particularly cephalopods. To examine the role of L- and D-Asp on a cephalopod receptor, we studied ligand gating of a squid glutamate receptor (SqGluR) expressed in HEK 239 (human embryonic kidney) cells. Under voltage clamp, application o...<br/><br/> Brown, Piscopo, Chun, Francone, Mirabile, D'Aniello (2006) <i>Amino Acids</i> <i></i> <i></i> : <br/>

http://publicationslist.org/e.r.brown/refid18 2008-02-02T05:36:34Z

In the marine mollusk Aplysia limacina, a substantial amount of endogenous D-aspartic acid (D-Asp) was found following its synthesis from L-aspartate by an aspartate racemase. Concentrations of D-Asp between 3.9 and 4.6 micromol/g tissue were found in the cerebral, abdominal, buccal, pleural, and pedal ganglia. In non nervous tissues, D-Asp occurred at a very low concentration compared to the nerv...<br/><br/>Patrizia Spinelli, Euan R Brown, Gabriele Ferrandino, Margherita Branno, Pier Giorgio Montarolo, Enrico D'Aniello, Rakesh K Rastogi, Biagio D'Aniello, Gabriella Chieffi Baccari, George Fisher, Antimo D'Aniello (2006) <i>J Cell Physiol</i> <i></i> <i></i> 206: 3 672-681<br/>

http://publicationslist.org/e.r.brown/refid20 2008-02-02T05:37:39Z

We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The geno...<br/><br/>Erica Sodergren, George M Weinstock, Eric H Davidson, R Andrew Cameron, Richard A Gibbs, Robert C Angerer, Lynne M Angerer, Maria Ina Arnone, David R Burgess, Robert D Burke, James A Coffman, Michael Dean, Maurice R Elphick, Charles A Ettensohn, Kathy R Foltz, Amro Hamdoun, Richard O Hynes, William H Klein, William Marzluff, David R McClay, Robert L Morris, Arcady Mushegian, Jonathan P Rast, L Courtney Smith, Michael C Thorndyke, Victor D Vacquier, Gary M Wessel, Greg Wray, Lan Zhang, Christine G Elsik, Olga Ermolaeva, Wratko Hlavina, Gretchen Hofmann, Paul Kitts, Melissa J Landrum, Aaron J Mackey, Donna Maglott, Georgia Panopoulou, Albert J Poustka, Kim Pruitt, Victor Sapojnikov, Xingzhi Song, Alexandre Souvorov, Victor Solovyev, Zheng Wei, Charles A Whittaker, Kim Worley, K James Durbin, Yufeng Shen, Olivier Fedrigo, David Garfield, Ralph Haygood, Alexander Primus, Rahul Satija, Tonya Severson, Manuel L Gonzalez-Garay, Andrew R Jackson, Aleksandar Milosavljevic, Mark Tong, Christopher E Killian, Brian T Livingston, Fred H Wilt, Nikki Adams, Robert Bellé, Seth Carbonneau, Rocky Cheung, Patrick Cormier, Bertrand Cosson, Jenifer Croce, Antonio Fernandez-Guerra, Anne-Marie Genevière, Manisha Goel, Hemant Kelkar, Julia Morales, Odile Mulner-Lorillon, Anthony J Robertson, Jared V Goldstone, Bryan Cole, David Epel, Bert Gold, Mark E Hahn, Meredith Howard-Ashby, Mark Scally, John J Stegeman, Erin L Allgood, Jonah Cool, Kyle M Judkins, Shawn S McCafferty, Ashlan M Musante, Robert A Obar, Amanda P Rawson, Blair J Rossetti, Ian R Gibbons, Matthew P Hoffman, Andrew Leone, Sorin Istrail, Stefan C Materna, Manoj P Samanta, Viktor Stolc, Waraporn Tongprasit, Qiang Tu, Karl-Frederik Bergeron, Bruce P Brandhorst, James Whittle, Kevin Berney, David J Bottjer, Cristina Calestani, Kevin Peterson, Elly Chow, Qiu Autumn Yuan, Eran Elhaik, Dan Graur, Justin T Reese, Ian Bosdet, Shin Heesun, Marco A Marra, Jacqueline Schein, Michele K Anderson, Virginia Brockton, Katherine M Buckley, Avis H Cohen, Sebastian D Fugmann, Taku Hibino, Mariano Loza-Coll, Audrey J Majeske, Cynthia Messier, Sham V Nair, Zeev Pancer, David P Terwilliger, Cavit Agca, Enrique Arboleda, Nansheng Chen, Allison M Churcher, F Hallböök, Glen W Humphrey, Mohammed M Idris, Takae Kiyama, Shuguang Liang, Dan Mellott, Xiuqian Mu, Greg Murray, Robert P Olinski, Florian Raible, Matthew Rowe, John S Taylor, Kristin Tessmar-Raible, D Wang, Karen H Wilson, Shunsuke Yaguchi, Terry Gaasterland, Blanca E Galindo, Herath J Gunaratne, Celina Juliano, Masashi Kinukawa, Gary W Moy, Anna T Neill, Mamoru Nomura, Michael Raisch, Anna Reade, Michelle M Roux, Jia L Song, Yi-Hsien Su, Ian K Townley, Ekaterina Voronina, Julian L Wong, Gabriele Amore, Margherita Branno, Euan R Brown, Vincenzo Cavalieri, Véronique Duboc, Louise Duloquin, Constantin Flytzanis, Christian Gache, François Lapraz, Thierry Lepage, Annamaria Locascio, Pedro Martinez, Giorgio Matassi, Valeria Matranga, Ryan Range, Francesca Rizzo, Eric Röttinger, Wendy Beane, Cynthia Bradham, Christine Byrum, Tom Glenn, Sofia Hussain, Gerard Manning, Esther Miranda, Rebecca Thomason, Katherine Walton, Athula Wikramanayke, Shu-Yu Wu, Ronghui Xu, C Titus Brown, Lili Chen, Rachel F Gray, Pei Yun Lee, Jongmin Nam, Paola Oliveri, Joel Smith, Donna Muzny, Stephanie Bell, Joseph Chacko, Andrew Cree, Stacey Curry, Clay Davis, Huyen Dinh, Shannon Dugan-Rocha, Jerry Fowler, Rachel Gill, Cerrissa Hamilton, Judith Hernandez, Sandra Hines, Jennifer Hume, Laronda Jackson, Angela Jolivet, Christie Kovar, Sandra Lee, Lora Lewis, George Miner, Margaret Morgan, Lynne V Nazareth, Geoffrey Okwuonu, David Parker, Ling-Ling Pu, Rachel Thorn, Rita Wright (2006) <i>Science</i> 314: 5801 941-952<br/>

http://publicationslist.org/e.r.brown/refid3 2008-02-02T05:25:54Z

Octopus vulgaris maintained under a 12/12h light/dark cycle exhibit a pronounced nocturnal activity pattern. Animals deprived of rest during the light period show a marked 'rebound' in activity in the following 24h. 'Active' octopuses attack faster than 'quiet' animals and brain activity recorded electrically intensifies during 'quiet' behaviour. Thus, in Octopus as in vertebrates, brain areas inv...<br/><br/>Euan R Brown, Stefania Piscopo, Rosanna De Stefano, Antonio Giuditta (2006) <i>Behav Brain Res</i> <i></i> <i></i> 172: 2 355-359<br/>

http://publicationslist.org/e.r.brown/refid7 2008-02-02T05:27:33Z

The tadpole larvae prosencephalon of the ascidian Ciona intestinalis contains a single large ventricle, along the inner walls of which lie two sensory organs: the otolith (a gravity-sensing organ) and the ocellus (a photo-sensing organ composed of a single cup-shaped pigment cell, about 20 photoreceptor cells, and three lens cells). Comparison has been drawn between the morphology and physiology o...<br/><br/>Salvatore D'Aniello, Enrico D'Aniello, Annamaria Locascio, Alessandra Memoli, Marcella Corrado, Monia Teresa Russo, Francesco Aniello, Laura Fucci, Euan R Brown, Margherita Branno (2006) <i>Differentiation</i> <i></i> <i></i> 74: 5 222-234<br/>

http://publicationslist.org/e.r.brown/refid6 2008-02-02T05:27:33Z

The aim of this study was to characterize the swimming behaviour of C. intestinalis larvae during the first 6 h after hatching by measuring tail muscle field potentials. This recording method allowed a quantitative description of the responses of the larva under light and dark conditions. Three different larval movements were distinguished by their specific frequencies: tail flicks, 'spontaneous' ...<br/><br/>Giuliana Zega, Michael C Thorndyke, Euan R Brown (2006) <i>J Exp Biol</i> <i></i> <i></i> 209: Pt 17 3405-3412<br/>

http://publicationslist.org/e.r.brown/refid8 2008-02-02T05:27:33Z

To examine the role of the amino acid GABA in the locomotion of basal chordates, we investigated the pharmacology of swimming and the morphology of GABA-immunopositive neurones in tadpole larvae of the ascidians Ciona intestinalis and Ciona savignyi. We verified that electrical recording from the tail reflects alternating muscle activity during swimming by correlating electrical signals with tail ...<br/><br/>E R Brown, A Nishino, Q Bone, I A Meinertzhagen, Y Okamura (2005) <i>Eur J Neurosci</i> <i></i> <i></i> 22: 10 2541-2548<br/>

http://publicationslist.org/e.r.brown/refid19 2008-02-02T05:36:34Z

The starfish Asterias rubens is an invertebrate deuterostome whose nervous system shows remarkable regenerative properties. To understand when full functionality of a damaged part of the nervous system recovers, and to follow nerve regeneration in detail, we carried out behavioural experiments with 29 starfishes that had the nerve in one of the arms sectioned in a mid-arm position. Loss and recove...<br/><br/>Stefania Piscopo, Rosanna De Stefano, Michael C Thorndyke, Euan R Brown (2005) <i>Behav Brain Res</i> <i></i> <i></i> 164: 1 36-41<br/>

http://publicationslist.org/e.r.brown/refid21 2008-02-02T05:40:25Z

Cyclic ADP-ribose (cADPr) is a second messenger that regulates intracellular free [Ca2+] ([Ca2+](i)) in a variety of cell types, including immature oocytes from the starfish Astropecten auranciacus. In this study, we employed confocal laser scanning microscopy and voltage clamp techniques to investigate the source of the cADPr-elicited Ca2+ wave originating from the cortical Ca2+ patches we have d...<br/><br/>F Moccia, G A Nusco, D Lim, E Ercolano, G Gragnaniello, E R Brown, L Santella (2003) <i>Pflugers Arch</i> 446: 5 541-552<br/>

http://publicationslist.org/e.r.brown/refid4 2008-02-02T05:25:54Z

Cellular mechanisms underlying learning and memory were investigated in the octopus using a brain slice preparation of the vertical lobe, an area of the octopus brain involved in learning and memory. Field potential recordings revealed long-term potentiation (LTP) of glutamatergic synaptic field potentials similar to that in vertebrates. These findings suggest that convergent evolution has led to ...<br/><br/>Binyamin Hochner, Euan R Brown, Marina Langella, Tal Shomrat, Graziano Fiorito (2003) <i>J Neurophysiol</i> <i></i> <i></i> 90: 5 3547-3554<br/>

http://publicationslist.org/e.r.brown/refid11 2008-02-02T05:31:08Z

Glutamate receptor types were examined at the chromatophore synapses of the squids Alloteuthis subulata and Loligo vulgaris, where nerve-induced muscle contraction causes chromatophore expansion. Immunoblotting with antibody raised against a squid AMPA receptor (sGluR) demonstrated that AMPA/kainate receptors are present in squid skin. Application of l-glutamate evoked chromatophore muscle contrac...<br/><br/>Pedro A Lima, Giovanna Nardi, Euan R Brown (2003) <i>Eur J Neurosci</i> <i></i> <i></i> 17: 3 507-516<br/>

http://publicationslist.org/e.r.brown/refid13 2008-02-02T05:31:08Z

Intracellular microelectrode recordings were made from presynaptic and postsynaptic regions of the third order giant synapses of the squids Alloteuthis subulata and Loligo vulgaris. Synaptically generated postsynaptic action potential trains, and excitatory postsynaptic potentials (EPSPs) were reversibly decreased by glycine, beta - alanine or taurine while presynaptic action potentials (APs) were...<br/><br/>I M Vinogradova, J Zajicek, S Gentile, E R Brown (2002) <i>Neurosci Lett</i> <i></i> <i></i> 325: 1 42-46<br/>

http://publicationslist.org/e.r.brown/refid12 2008-02-02T05:31:08Z

Ionic currents from Schwann cells isolated enzymatically from the giant axons of the squids Loligo forbesi, Loligo vulgaris and Loligo bleekeri were compared with those obtained in situ. Macroscopic and single channel ionic currents were recorded using whole-cell voltage and patch clamp. In the whole-cell configuration, depolarisation from negative holding potentials evoked two voltage-dependent c...<br/><br/>Isao Inoue, Izuo Tsutsui, N Joan Abbott, Euan R Brown (2002) <i>J Physiol</i> <i></i> <i></i> 541: Pt 3 769-778<br/>

http://publicationslist.org/e.r.brown/refid14 2008-02-02T05:31:08Z

Voltage-dependent calcium currents in vertebrate (Scyliorhinus canicula), protochordate (Branchiostoma lanceolatum), and invertebrate (Alloteuthis subulata) skeletal and striated muscle were examined under whole-cell voltage clamp. Nifedipine (10 microM) suppressed and cobalt (5 mM) blocked striated/skeletal muscle calcium currents in all of the animals examined, confirming that they are of the L-...<br/><br/>C M Rogers, E R Brown (2001) <i>Exp Physiol</i> <i></i> <i></i> 86: 6 689-694<br/>

http://publicationslist.org/e.r.brown/refid15 2008-02-02T05:31:08Z

Synaptosomes from the optic lobes of squid (Loligo forbesi) were prepared by homogenization and allowed to settle onto glass coverslips. Synaptosomes were loaded with Ca(2+) sensitive dyes (Fura-2 AM, Calcium Green-1 AM and Calcium Green-5N AM), visualized by light microscopy and Ca(2+) sensitive fluorescence signals recorded and analyzed. With Fura-2, resting Ca(2+) was found to be 80 nM (n = 10,...<br/><br/>J C Benech, P A Lima, J R Sotelo, E R Brown (2000) <i>J Neurosci Res</i> <i></i> <i></i> 62: 6 840-846<br/>

http://publicationslist.org/e.r.brown/refid26 2008-02-02T05:51:24Z

Excitation-contraction (EC) coupling was studied in central zone mantle muscle fibres of a squid (Alloteuthis subulata), a cuttlefish (Sepia officinalis) and an octopod (Eledone cirrhosa). Thin slices of muscle were used for twitch experiments and enzymatic isolation of single fibres for whole-cell patch-clamp studies. The current required for a supramaximal twitch response during direct stimulati...<br/><br/> Rogers, Nelson, Brown (1997) <i>J Exp Biol</i> <i></i> <i></i> 200 (Pt 23): 3033-3041<br/>

http://publicationslist.org/e.r.brown/refid16 2008-02-02T05:31:08Z

1. During action potential trains in giant axons from the squid Sepioteuthis, decline of the peak level of the undershoot potential was observed. The time course of the decline of the undershoot could be fitted with a three-exponential function with time constants of approximately 25, approximately 400 and approximately 7,000 ms, respectively. 2. When the osmolarity of the external solution was do...<br/><br/>I Inoue, I Tsutsui, E R Brown (1997) <i>J Physiol</i> <i></i> <i></i> 500 ( Pt 2): 355-366<br/>

http://publicationslist.org/e.r.brown/refid27 2008-02-02T05:51:24Z

The respiratory flow of water over the gills of the cuttlefish Sepia officinalis at rest is produced by the alternate activity of the radial muscles of the mantle and the musculature of the collar flaps; mantle circular muscle fibres are not involved. Inspiration takes place as the radial fibres contract, thinning the mantle and expanding the mantle cavity. The rise in mantle cavity pressure (up t...<br/><br/> Bone, Brown, Travers (1994) <i>J Exp Biol</i> <i></i> <i></i> 194: 1 153-165<br/>

http://publicationslist.org/e.r.brown/refid22 2008-02-02T05:43:23Z

K+ clearance following axon activity was measured around squid axons and found to be 20 times more efficient in preparations that were undissected. Around dissected preparations, Schwann cells were found to be swollen and vacuolated. It is suggested that traditional dissection methods damage Schwann cells and their K+ clearance function is impaired.<br/><br/>E R Brown (1993) <i>Jpn J Physiol</i> <i></i> <i></i> 43 Suppl 1: S279-S284<br/>

http://publicationslist.org/e.r.brown/refid17 2008-02-02T05:31:08Z

The ultrastructure of the Schwann cell layer surrounding the giant axon of the squid Alloteuthis subulata is described, and the permeability of extracellular compartments assessed by exposure to electron-dense tracers. Morphometric analysis is used to deduce the number, size and shape of the Schwann cells, and the routes for ion flux across the Schwann cell layer. Axons (mean diameter 233 microns)...<br/><br/>E R Brown, N J Abbott (1993) <i>J Neurocytol</i> <i></i> <i></i> 22: 4 283-298<br/>

http://publicationslist.org/e.r.brown/refid24 2008-02-02T05:43:23Z

N J Abbott, Y Pichon, E R Brown, I Inoue, F Kukita, P A Revest, I C Smith (1991) <i>Ann N Y Acad Sci</i> <i></i> <i></i> 633: 607-609<br/>

http://publicationslist.org/e.r.brown/refid23 2008-02-02T05:43:23Z

The first successful dye-fills of Schwann cells around the split giant axon of Loligo show them to be spindle-shaped cells ca. 600 microns long and 20 microns wide lying parallel to the axonal axis. There are some 50,000 Schwann cells per cm2 of axonal membrane. Only a small part (ca. 6% of each Schwann cell membrane) is in contact with the periaxonal space, the remainder is overlain by adjacent S...<br/><br/>E R Brown, Q Bone, K P Ryan, N J Abbott (1991) <i>Proc Biol Sci</i> <i></i> <i></i> 243: 1308 255-262<br/>

http://publicationslist.org/e.r.brown/refid25 2008-02-02T05:43:23Z

N J Abbott, Y Pichon, I Inoue, E R Brown, E M Lieberman, P A Revest, I C Smith (1989) <i>Acta Physiol Scand Suppl</i> <i></i> <i></i> 582: <br/>