http://publicationslist.org/data/elifsu.sabuncu/atom.xmlElifsu Sabuncu's Publications List Elifsu Sabuncuhttp://publicationslist.org/elifsu.sabuncu$basepathfavicon.icoRecent additions to Elifsu Sabuncu's PublicationsList.org pagehttp://publicationslist.org/publications.png2011-02-17T13:32:15Z http://publicationslist.org/elifsu.sabuncu/refid6 2009-06-25T00:51:08Z Significant Reduction of Antibiotic Use in the Community after a Nationwide Campaign in France, 2002–2007 Background Overuse of antibiotics is the main force driving the emergence and dissemination of bacterial resistance in the community. France consumes more antibiotics and has the highest rate of beta-lactam resistance in Streptococcus pneumoniae than any other European country. In 2001, the government initiated “Keep Antibiotics Working”; the program's main component was a campaign entitled...<br/><br/>Sabuncu Elifsu, David Julie, Bernède-Bauduin Christian, Pépin Sophie, Leroy Michel, Boëlle Pierre-Yves, Watier Laurence, Guillemot Didier (2009) <i>PLoS Med</i> 6: 6 e1000084<br/> http://publicationslist.org/elifsu.sabuncu/refid9 2011-02-17T13:11:03Z Mathias Théry, "La vie après la mort d'Henrietta Lacks", 2004, France, 23 min (ENSAD) ; Mathias Théry et Étienne Chaillou, "Cherche toujours", 2008, France, 52 min (Arte France / Les Films d'ici) Comment entrer dans l’intimité d’un chercheur ? Comment rendre compte de la vision du monde qui est la sienne ? Comment accéder à une authentique recherche en train de se faire ? À ces questions, le réalisateur Mathias Théry donne quelques éléments de réponse dans ses deux films, La vie après la mort d’Henrietta Lacks (ci-après VAMHL) et Cherche toujours (CT). Le premier constitu...<br/><br/>Antoine Blanchard, Hélène Monfeuillard, Elifsu Sabuncu (2009) <i></i><br/> http://publicationslist.org/elifsu.sabuncu/refid7 2009-03-09T00:20:08Z Initier aux approches interdisciplinaires dès le master : l’exemple du master 2 "Approches Interdisciplinaires du Vivant" Livio Riboli-Sasco, Elifsu Sabuncu (2008) <i>Natures Sciences Sociétés</i> 16: Supp 24-30<br/> http://publicationslist.org/elifsu.sabuncu/refid5 2009-03-08T23:09:18Z Glycan chains modulate prion protein binding to immobilized metal ions. PrP(c) is the normal isoform of the prion protein which can be converted into PrP(Sc), the pathology-associated conformer in prion diseases. It contains two N-linked glycan chains attached to the C-proximal globular domain. While the biological functions of PrP(c) are still unknown, its ability to bind Cu(2+) is well documented. The main Cu(2+)-binding sites are located in the N-proximal, unstruct...<br/><br/>Mohammed Moudjou, Julie Bernard, Elifsu Sabuncu, Christelle Langevin, Hubert Laude (2007) <i>Neurochem Int</i> 50: 5 689-695<br/> http://publicationslist.org/elifsu.sabuncu/refid8 2009-03-09T00:28:49Z Étude de la susceptibilité génétique à l’agent de la tremblante du mouton dans un modèle cellulaire permissif aux prions Elifsu Sabuncu (2005) <br/> http://publicationslist.org/elifsu.sabuncu/refid4 2009-03-08T23:06:59Z Prion proteins from susceptible and resistant sheep exhibit some distinct cell biological features. It is well established that natural polymorphisms in the coding sequence of the PrP protein can control the expression of prion disease. Studies with a cell model of sheep prion infection have shown that ovine PrP allele associated with resistance to sheep scrapie may confer resistance by impairing the multiplication of the infectious agent. To further explore the biochemical and cellular mechanis...<br/><br/>Elifsu Sabuncu, Sophie Paquet, Jérome Chapuis, Mohammed Moudjou, Thanh Lan Lai, Jacques Grassi, Udo Baron, Hubert Laude, Didier Vilette (2005) <i>Biochem Biophys Res Commun</i> 337: 3 791-798<br/> http://publicationslist.org/elifsu.sabuncu/refid2 2009-03-08T23:04:01Z Prion infection of epithelial Rov cells is a polarized event. During prion infections, the cellular glycosylphosphatidylinositol-anchored glycoprotein PrP is converted into a conformational isoform. This abnormal conformer is thought to recruit and convert the normal cellular PrP into a likeness of itself and is proposed to be the infectious agent. We investigated the distribution of the PrP protein on the surface of Rov cells, an epithelial cell line highly...<br/><br/>Sophie Paquet, Elifsu Sabuncu, Jean-Louis Delaunay, Hubert Laude, Didier Vilette (2004) <i>J Virol</i> 78: 13 7148-7152<br/> http://publicationslist.org/elifsu.sabuncu/refid3 2009-03-08T23:06:05Z Glycan-controlled epitopes of prion protein include a major determinant of susceptibility to sheep scrapie. A key feature of prion encephalopathies is the accumulation of a misfolded form of the host glycoprotein PrP. Cell-free and cell culture studies have shown that the efficiency of conversion of PrP into the disease-associated form is influenced by its amino acid sequence and also by its carbohydrate moiety. Here, we characterize four novel glycoform-dependent monoclonal antibodies raised against pr...<br/><br/>Mohammed Moudjou, Eric Treguer, Human Rezaei, Elifsu Sabuncu, Erdmute Neuendorf, Martin H Groschup, Jeanne Grosclaude, Hubert Laude, Erdi Neuendorf (2004) <i>J Virol</i> 78: 17 9270-9276<br/> http://publicationslist.org/elifsu.sabuncu/refid1 2009-03-08T23:01:35Z PrP polymorphisms tightly control sheep prion replication in cultured cells. Prion diseases are fatal neurodegenerative disorders of animals and humans that are characterized by the conversion of the host-encoded prion protein (PrP) to an abnormal isoform. In several species, including humans, polymorphisms in the gene encoding the PrP protein tightly control susceptibility of individuals toward this disease. In the present study we show that Rov cells expressing an ovine ...<br/><br/>Elifsu Sabuncu, Stéphanie Petit, Annick Le Dur, Thanh Lan Lai, Jean-Luc Vilotte, Hubert Laude, Didier Vilette (2003) <i>J Virol</i> 77: 4 2696-2700<br/>