http://publicationslist.org/data/fayaz.mir/atom.xmlFayaz Mir's Publications List Fayaz Mirhttp://publicationslist.org/fayaz.mir$basepathfavicon.icoRecent additions to Fayaz Mir's PublicationsList.org pagehttp://publicationslist.org/publications.png2009-02-04T13:34:29Z http://publicationslist.org/fayaz.mir/refid1 2009-02-04T13:26:17Z Mycobacterium tuberculosis 6-kDa early secreted antigenic target (ESAT-6) protein downregulates lipopolysaccharide induced c-myc expression by modulating the extracellular signal regulated kinases 1/2. BACKGROUND: Mycobacterium tuberculosis (Mtb) causes death of 2-3 million people every year. The persistence of the pathogenic mycobacteria inside the macrophage occurs through modulation of host cell signaling which allows them, unlike the other non-pathogenic species, to survive inside the host. The secretory proteins of M. tuberculosis have gained attention in recent years both as vaccine candid...<br/><br/>Niladri Ganguly, Pham H Giang, Sandip K Basu, Fayaz Ahmad Mir, Imran Siddiqui, Pawan Sharma (2007) <i>BMC Immunol</i> 8: <br/> http://publicationslist.org/fayaz.mir/refid2 2009-02-04T13:27:18Z A multivalent combination of experimental antituberculosis DNA vaccines based on Ag85B and regions of difference antigens. Two candidate DNA vaccines based on the proteins CFP10 and CFP21 encoded by regions of difference (RDs) of Mycobacterium tuberculosis were evaluated individually and in multivalent combination with the immunodominant protein Ag85B for induction of protective immune responses against experimental tuberculosis. Experimental DNA vaccines induced substantial levels of cell-mediated immune responses as...<br/><br/>Ajay Grover, Mir Fayaz Ahmed, Balwan Singh, Indu Verma, Pawan Sharma, G K Khuller (2006) <i>Microbes Infect</i> 8: 9-10 2390-2399<br/> http://publicationslist.org/fayaz.mir/refid3 2009-02-04T13:28:41Z Expression and purification of the Mycobacterium tuberculosis complex-restricted antigen CFP21 to study its immunoprophylactic potential in mouse model. Secreted proteins encoded by different regions of difference (RDs) from the genome of Mycobacterium tuberculosis have been considered as attractive candidates for vaccination against tuberculosis owing to their absence in most BCG strains. In this study, the structural gene for the RD2 locus encoding protein CFP21 was PCR amplified and expressed as a fusion protein with hexahistidine residues in E...<br/><br/>Ajay Grover, Mir Fayaz Ahmed, Indu Verma, Pawan Sharma, G K Khuller (2006) <i>Protein Expr Purif</i> 48: 2 274-280<br/>