http://publicationslist.org/data/henrik.von.euler/atom.xml Henrik von Eulerhttp://publicationslist.org/henrik.von.euler$basepathfavicon.icoRecent additions to Henrik von Euler's PublicationsList.org pagehttp://publicationslist.org/publications.png2008-06-04T07:02:48Z http://publicationslist.org/henrik.von.euler/refid1 2008-06-04T07:00:38Z

Cutaneous canine melanomas are usually benign in contrast to human malignant melanoma. However, the canine oropharyngeal, uveal, and mucocutaneous neoplasms are aggressive and have metastatic potential. Surgery and to a lesser extent radiotherapy and chemotherapy are widely adopted treatments but are seldom curative in advanced stages. The similarities between human and canine melanoma make sponta...<br/><br/>Henrik von Euler, Arian Sadeghi, Björn Carlsson, Patricio Rivera, Angelica Loskog, Thomas Segall, Olle Korsgren, Thomas H Tötterman (2008) <i>J Immunother</i> <i></i> <i></i> 31: 4 377-384<br/>

http://publicationslist.org/henrik.von.euler/refid4 2008-06-04T07:00:38Z

The dorsal hair ridge in Rhodesian and Thai Ridgeback dogs is caused by a dominant mutation that also predisposes to the congenital developmental disorder dermoid sinus. Here we show that the causative mutation is a 133-kb duplication involving three fibroblast growth factor (FGF) genes. FGFs play a crucial role in development, suggesting that the ridge and dermoid sinus are caused by dysregulatio...<br/><br/>Nicolette H C Salmon Hillbertz, Magnus Isaksson, Elinor K Karlsson, Eva Hellmén, Gerli Rosengren Pielberg, Peter Savolainen, Claire M Wade, Henrik von Euler, Ulla Gustafson, Ake Hedhammar, Mats Nilsson, Kerstin Lindblad-Toh, Leif Andersson, Göran Andersson (2007) <i>Nat Genet</i> <i></i> <i></i> 39: 11 1318-1320<br/>

http://publicationslist.org/henrik.von.euler/refid3 2008-06-04T07:00:38Z

With several hundred genetic diseases and an advantageous genome structure, dogs are ideal for mapping genes that cause disease. Here we report the development of a genotyping array with approximately 27,000 SNPs and show that genome-wide association mapping of mendelian traits in dog breeds can be achieved with only approximately 20 dogs. Specifically, we map two traits with mendelian inheritance...<br/><br/>Elinor K Karlsson, Izabella Baranowska, Claire M Wade, Nicolette H C Salmon Hillbertz, Michael C Zody, Nathan Anderson, Tara M Biagi, Nick Patterson, Gerli Rosengren Pielberg, Edward J Kulbokas, Kenine E Comstock, Evan T Keller, Jill P Mesirov, Henrik von Euler, Olle Kämpe, Ake Hedhammar, Eric S Lander, Göran Andersson, Leif Andersson, Kerstin Lindblad-Toh (2007) <i>Nat Genet</i> <i></i> <i></i> 39: 11 1321-1328<br/>

http://publicationslist.org/henrik.von.euler/refid2 2008-06-04T07:00:38Z

The objectives of this study were to describe the incidence of, survival until, and survival after the diagnosis of canine bone tumors by breed, sex, age, and geographic location of residence. Dogs under 10 y old and insured by a Swedish insurance company between 1995 and 2002 were studied. In total, 764 dogs had claims for bone tumors, and the incidence rate was 5.5 cases per 10 000 dog-years at ...<br/><br/>Agneta Egenvall, Ane Nødtvedt, Henrik von Euler (2007) <i>Can J Vet Res</i> <i></i> <i></i> 71: 4 292-299<br/>

http://publicationslist.org/henrik.von.euler/refid7 2008-06-04T07:00:38Z

The aim of this study was to evaluate an enzyme-linked immunosorbent assay (ELISA), for determination of serum thymidine kinase 1 (sTK1) activity in dogs with malignant lymphoma (ML) and compare it with a thymidine kinase (TK) radioenzymatic assay (TK-REA). The TK-REA has recently been shown to be useful in determining the clinical stage and prognosis in canine ML. In addition, serum lactate dehyd...<br/><br/>Henrik P von Euler, Anders B Ohrvik, Staffan K Eriksson (2006) <i>Res Vet Sci</i> <i></i> <i></i> 80: 1 17-24<br/>

http://publicationslist.org/henrik.von.euler/refid5 2008-06-04T07:00:38Z

Multiple endocrine neoplasia (MEN) is defined as concurrent neoplasia or hyperplasia in more than one endocrine gland. MEN is well known in humans and has also been reported in small animals. We report on a dog family of a mixed breed with Alaskan malamute as a major influence, where three members developed thyroid carcinomas and another dog had clinical signs mimicking the other three but without...<br/><br/>Jia-Jing Lee, Catharina Larsson, Weng-Onn Lui, Anders Höög, Henrik Von Euler (2006) <i>Int J Oncol</i> <i></i> <i></i> 29: 5 1173-1182<br/>

http://publicationslist.org/henrik.von.euler/refid6 2008-06-04T07:00:38Z

Heterogeneous gene expression in tumours and the degradation of RNA when sampling under non-RNAse-free conditions may limit the potential benefit of cDNA array studies. This study examines changes in the integrity of RNA by means of RNA gel electrophoresis at various post-operative intervals on canine mammary tumours (n=10) and malignant lymphoma (n=1). The tumours were cut into pieces (3-5 mm dia...<br/><br/>Henrik Von Euler, Reza Khoshnoud, Qimin He, Aida Khoshnoud, Tommy Fornander, Lars-Erik Rutqvist, Sven Skog (2005) <i>Int J Mol Med</i> <i></i> <i></i> 16: 6 979-985<br/>

http://publicationslist.org/henrik.von.euler/refid8 2008-06-04T07:00:38Z

The main objective of this study was to describe the incidence of mammary tumors (MTs) and the survival after MTs, in female dogs between 3 and 10 years of age (insured for veterinary care and with life insurance in a Swedish animal-insurance company) from 1995 to 2002. Measures of incidence are presented crudely, by breed and across age categories and birth cohorts (1991-1998). The survivals unti...<br/><br/>Agneta Egenvall, Brenda N Bonnett, Patrik Ohagen, Pekka Olson, Ake Hedhammar, Henrik von Euler (2005) <i>Prev Vet Med</i> <i></i> <i></i> 69: 1-2 109-127<br/>

http://publicationslist.org/henrik.von.euler/refid9 2008-06-04T07:00:38Z

Serum thymidine kinase (sTK) activity was evaluated as a tumor marker for canine malignant lymphoma (ML). The objective was to investigate if sTK, as in humans, could be used as a prognostic marker for survival time in dogs with ML and if sTK could identify early signs of progression of disease in treated dogs. Serum samples from 52 dogs with ML were tested for initial TK activity. Samples from 21...<br/><br/>Henrik von Euler, Roland Einarsson, Ulf Olsson, Anne-Sofie Lagerstedt, Staffan Eriksson (2004) <i>J Vet Intern Med</i> <i></i> <i></i> 18: 5 696-702<br/>

http://publicationslist.org/henrik.von.euler/refid10 2008-06-04T07:00:38Z

BACKGROUND: Several authors have recently reported encouraging results from Electrochemical treatment (EChT) in malignant tumours. However, EChT is not established and mechanisms are not completely understood. In vivo studies were conducted to evaluate the toxic changes and effectiveness of EChT on an animal tumour model. METHODS: Tumours were induced by injecting cells from the R3230AC rat mammar...<br/><br/>H von Euler, K Stråhle, A Thörne, G Yongqing (2004) <i>Bioelectrochemistry</i> <i></i> <i></i> 62: 1 57-65<br/>

http://publicationslist.org/henrik.von.euler/refid11 2008-06-04T07:02:16Z

INTRODUCTION: Electrochemical treatment (EChT) has been taken under serious consideration as being one of several techniques for local treatment of malignancies. The advantage of EChT is the minimal invasive approach and the absence of serious side effects. Macroscopic, histopathological and ultra-structural findings in liver following a four-electrode configuration (dog) and a two-electrode EChT ...<br/><br/>Henrik von Euler, Jerker M Olsson, Kjell Hultenby, Anders Thörne, Anne-Sofie Lagerstedt (2003) <i>Bioelectrochemistry</i> <i></i> <i></i> 59: 1-2 89-98<br/>

http://publicationslist.org/henrik.von.euler/refid12 2008-06-04T07:02:16Z

INTRODUCTION: The aim of this study was to evaluate the cellular toxicity of different pH levels on the R3230AC mammary tumour cell line (clone-D) in vitro and to determine in what way the pH affects the tumour cells. The results could be used to interpret the cell damaging effects seen in electrochemical treatment of tumours (EChT), where pH alteration in tissue is the major event. METHODS: Tumou...<br/><br/>Henrik von Euler, Agneta Söderstedt, Anders Thörne, Jerker M Olsson, Guo Yongqing (2002) <i>Bioelectrochemistry</i> <i></i> <i></i> 58: 2 163-170<br/>

http://publicationslist.org/henrik.von.euler/refid13 2008-06-04T07:02:16Z

BACKGROUND: A reinvented technique for tumour therapy, electrochemical treatment (EChT), is attracting increasing attention. This study compared results from treatment of liver and mammary tissue focusing on destruction and pH changes in the tissue close to the treatment electrodes. Subsequently, data were compared with a dose-planning model. METHODS: Mammary or liver tissue in 50 adult female Spr...<br/><br/>H von Euler, E Nilsson, J M Olsson, A S Lagerstedt (2001) <i>Bioelectrochemistry</i> <i></i> <i></i> 54: 2 117-124<br/>

http://publicationslist.org/henrik.von.euler/refid14 2008-06-04T07:02:16Z

The electrochemical treatment (EChT) of tumours implies that tumour tissue is treated with a continuous direct current through two or more electrodes placed in or near the tumour. The treatment offers considerable promise of a safe, simple and relatively noninvasive anti-tumour therapy for treatment of localised malignant as well as benign tumours. Although more than 10,000 patients have been trea...<br/><br/>E Nilsson, H von Euler, J Berendson, A Thörne, P Wersäll, I Näslund, A S Lagerstedt, K Narfström, J M Olsson (2000) <i>Bioelectrochemistry</i> <i></i> <i></i> 51: 1 1-11<br/>