http://publicationslist.org/data/jonas.hauser/atom.xml Jonas Hauserhttp://publicationslist.org/jonas.hauser$basepathfavicon.icoRecent additions to Jonas Hauser's PublicationsList.org pagehttp://publicationslist.org/publications.png2012-12-10T12:32:05Z http://publicationslist.org/jonas.hauser/refid12 2012-12-10T12:27:31Z

RATIONALE: The startle reflex to a sudden intense acoustic pulse stimulus is attenuated if the pulse is shortly preceded by a weak prepulse stimulus. This represents a form of sensory gating, known as prepulse inhibition (PPI), observable across species. PPI is modulated by dopamine and readily disrupted by acute amphetamine. Prior repeated exposures to amphetamine also disrupt PPI even when the d...<br/><br/>Daria Peleg-Raibstein, Jonas Hauser, Luis H Llano Lopez, Joram Feldon, Pascual A Gargiulo, Benjamin K Yee (2012) <i>Psychopharmacology (Berl)</i> <i></i> <i></i> : <br/>

http://publicationslist.org/jonas.hauser/refid11 2012-12-10T12:25:38Z

J Hauser (2012) <i>Adaptive and Maladaptive Aspects of Developmental Stress </i> <br/>

http://publicationslist.org/jonas.hauser/refid1 2010-08-03T11:34:07Z

The Morris water maze (WM) is a common spatial memory test in rats. It has been adapted for evaluating genetic manipulations in mice. One major acknowledged problem of this cross-species translation is floating. We investigated here in mice the feasibility and practicality of an alternative paradigm-the cheeseboard (CB), which is a dry version of the WM, in a within-subject design allowing direct ...<br/><br/>L Llano Lopez, J Hauser, J Feldon, P A Gargiulo, B K Yee (2010) <i>Behav Brain Res</i> <i></i> <i></i> 209: 1 85-92<br/>

http://publicationslist.org/jonas.hauser/refid3 2010-08-03T11:34:07Z

RATIONALE: A sensitized dopamine system may be linked to the genesis of psychotic symptoms in schizophrenia. Following withdrawal from amphetamine exposures, psychotic-like traits have been robustly demonstrated, but the presence of cognitive/mnemonic deficits remains uncertain. METHODS: Adult male Lewis and Fischer rats, differing in cognitive performance, were exposed intermittently to escalatin...<br/><br/>Daria Peleg-Raibstein, Benjamin K Yee, Joram Feldon, Jonas Hauser (2009) <i>Psychopharmacology (Berl)</i> <i></i> <i></i> 206: 4 603-621<br/>

http://publicationslist.org/jonas.hauser/refid2 2010-08-03T11:34:07Z

Prenatal stress can affect foetal neurodevelopment and result in increased risk of depression in adulthood. It promotes increased maternal hypothalamo-pituitary-adrenal gland (HPA) secretion of glucocorticoid (GC), leading to increased foetal and maternal GC receptor activity. Prenatal GC receptor activity is also increased during prenatal treatment with dexamethasone (DEX), which is commonly pres...<br/><br/>Jonas Hauser, Joram Feldon, Christopher R Pryce (2009) <i>Horm Behav</i> <i></i> <i></i> 56: 4 364-375<br/>

http://publicationslist.org/jonas.hauser/refid4 2010-08-03T11:34:07Z

Synthetic glucocorticoids such as dexamethasone (DEX) are commonly used to prevent respiratory distress syndrome in preterm infants, but there is emerging evidence of subsequent neurobehavioral abnormalities (e.g. problems with inattention/hyperactivity). In the present study, we exposed pregnant common marmosets (Callithrix jacchus, primates) to daily repeated DEX (5 mg/kg by mouth) during either...<br/><br/>Jonas Hauser, Alana Knapman, Nicole R Zürcher, Sonia Pilloud, Claudia Maier, Rochellys Diaz-Heijtz, Hans Forssberg, Andrea Dettling, Joram Feldon, Christopher R Pryce (2008) <i>Endocrinology</i> <i></i> <i></i> 149: 12 6343-6355<br/>

http://publicationslist.org/jonas.hauser/refid5 2010-08-03T11:34:07Z

The prophylactic treatment of diagnosed preterm delivery with synthetic glucocorticoids, such as dexamethasone (DEX), is commonplace. Long-term effects of such treatment are not well understood. In the present study, we exposed pregnant common marmosets (Callithrix jacchus), small-bodied monkeys that are therefore advantageous for long-term primate studies, to daily repeated DEX (5 mg/kg orally) e...<br/><br/>Jonas Hauser, Andrea Dettling-Artho, Sonia Pilloud, Claudia Maier, Alana Knapman, Joram Feldon, Christopher R Pryce (2007) <i>Endocrinology</i> <i></i> <i></i> 148: 4 1813-1822<br/>

http://publicationslist.org/jonas.hauser/refid6 2010-08-03T11:34:07Z

Prenatal stress is an important risk factor in schizophrenia, and the aetiological factors mediating this relationship are central to the neurodevelopmental hypothesis of schizophrenia. The glucocorticoid receptor (GR) agonist dexamethasone (DEX) is commonly prescribed for prenatal conditions, and results in GR activation, which is part of the stress response. To investigate animal evidence for wh...<br/><br/>Jonas Hauser, Joram Feldon, Christopher R Pryce (2006) <i>Behav Brain Res</i> <i></i> <i></i> 175: 1 51-61<br/>

http://publicationslist.org/jonas.hauser/refid9 2010-08-03T11:34:32Z

Thyroid hormone plays an important role in regulating the development and regeneration of the nervous system. Our previous work showed that local administration of triiodothyronine (T3) at the level of transected rat sciatic nerve increased the number and diameter of regenerated axons, but the mechanism underlying the improved regeneration is still unclear. Here, we have investigated the effect of...<br/><br/>I Voria, J Hauser, A Axis, M Schenker, S Bichet, T Kuntzer, G Grenningloh, I Barakat-Walter (2006) <i>Exp Neurol</i> <i></i> <i></i> 197: 1 258-267<br/>

http://publicationslist.org/jonas.hauser/refid8 2010-08-03T11:34:07Z

Prepulse inhibition (PPI) refers to the phenomenon in which a low-intensity prepulse stimulus attenuates the reflexive response to a succeeding startle-eliciting pulse stimulus. The hippocampus, among other structures, is believed to play an important role in the modulation of PPI expression. In alpha5(H105R) mutant mice, the expression of the alpha5 subunit-containing GABA(A) receptors in the hip...<br/><br/>J Hauser, U Rudolph, R Keist, H Möhler, J Feldon, B K Yee (2005) <i>Mol Psychiatry</i> <i></i> <i></i> 10: 2 201-207<br/>

http://publicationslist.org/jonas.hauser/refid7 2010-08-03T11:34:07Z

A reduction in alpha5 subunit-containing gamma-aminobutyric acid (GABA)A receptors has been reported to enhance some forms of learning in mutant mouse models. This effect has been attributed to impaired alpha5 GABAA receptor-mediated inhibitory modulation in the hippocampus. The introduction of a point mutation (H105R) in the alpha5 subunit is associated with a specific reduction of alpha5 subunit...<br/><br/>Benjamin K Yee, Jonas Hauser, Vadim V Dolgov, Ruth Keist, Hanns Möhler, Uwe Rudolph, Joram Feldon (2004) <i>Eur J Neurosci</i> <i></i> <i></i> 20: 7 1928-1936<br/>

http://publicationslist.org/jonas.hauser/refid10 2010-08-03T11:34:53Z

INTRODUCTION: There has been renewed interest in mushroom medicinal properties. We studied cholesterol lowering properties of Ganoderma lucidum (Gl), a renowned medicinal species. RESULTS: Organic fractions containing oxygenated lanosterol derivatives inhibited cholesterol synthesis in T9A4 hepatocytes. In hamsters, 5% Gl did not effect LDL; but decreased total cholesterol (TC) 9.8%, and HDL 11.2%...<br/><br/>A Berger, D Rein, E Kratky, I Monnard, H Hajjaj, I Meirim, C Piguet-Welsch, J Hauser, K Mace, P Niederberger (2004) <i>Lipids Health Dis</i> <i></i> <i></i> 3: <br/>