http://publicationslist.org/data/kamil.oender/atom.xml kamil oenderhttp://publicationslist.org/kamil.oender$basepathfavicon.icoRecent additions to kamil oender's PublicationsList.org pagehttp://publicationslist.org/publications.png2009-01-25T23:19:36Z http://publicationslist.org/kamil.oender/refid1 2009-01-25T23:17:09Z

ABSTRACT: BACKGROUND: Protein-protein interaction (PPI) data sets generated by high-throughput experiments are contaminated by large numbers of erroneous PPIs. Therefore, computational methods for PPI validation are necessary to improve the quality of such data sets. Against the background of the theory that most extant PPIs arose as a consequence of gene duplication, the sensitive search for homo...<br/><br/> Frech, Kommenda, Dorfer, Kern, Hintner, Bauer, Oender (2009) <i>BMC Bioinformatics</i> <i></i> <i></i> 10: 1 <br/>

http://publicationslist.org/kamil.oender/refid2 2009-01-25T23:17:09Z

The contribution of extracellular matrix components to intrinsic skin aging has been investigated thoroughly, however, there is little information as to the role of the cytoskeletal proteins in this process. Therefore, we compared the expression of the constituents of the cytoskeleton, keratins 1-23 (K1-K23) as well as junction-plakoglobin (JUP), alpha-tubulin (TUBA), and beta-actin (ACTB) in huma...<br/><br/>Kamil Oender, Andrea Trost, Christoph Lanschuetzer, Martin Laimer, Michael Emberger, Michael Breitenbach, Klaus Richter, Helmut Hintner, Johann W Bauer (2008) <i>Mech Ageing Dev</i> <i></i> <i></i> 129: 10 563-571<br/>

http://publicationslist.org/kamil.oender/refid11 2009-01-25T23:18:32Z

BACKGROUND: The bacterium Staphylococcus aureus causes significant morbidity and mortality in humans, primarily due to the emergence of strains that are resistant to antibiotics - notably methicillin-resistant S. aureus (MRSA) isolates. Development of effective strategies for the control and treatment of MRSA infections may best be achieved through 'omics' approaches, which first requires cloning ...<br/><br/>Christina J Brandner, Richard H Maier, Daryl S Henderson, Helmut Hintner, Johann W Bauer, Kamil Onder (2008) <i>BMC Genomics</i> <i></i> <i></i> 9: <br/>

http://publicationslist.org/kamil.oender/refid10 2009-01-25T23:18:32Z

The yeast two-hybrid (Y2H) system is a powerful method to identify protein-protein inter-actions (PPI) in vivo, requiring minimal prior information of the putative interactors. The time and effort required for each experiment can be significantly reduced if the "bait" and the "prey" proteins are cloned into specific recombination-amenable two-hybrid vectors. We describe the construction of a readi...<br/><br/>Richard Maier, Christina Brandner, Helmut Hintner, Johann Bauer, Kamil Onder (2008) <i>Biotechniques</i> <i></i> <i></i> 45: 3 235-244<br/>

http://publicationslist.org/kamil.oender/refid12 2009-01-25T23:18:32Z

Mutations in the gene coding for the transmembrane receptor protein Patched (PTCH) are implicated in the autosomal dominant disorder Gorlin syndrome (also known as naevoid basal cell carcinoma syndrome), characterized by congenital abnormalities and cancer predisposition. Tumour promotion is thought to be associated with aberrant function of PTCH, leading to misregulation of the hedgehog signallin...<br/><br/>M Laimer, K Onder, P Schlager, C M Lanschuetzer, M Emberger, S Selhofer, H Hintner, J W Bauer (2008) <i>Br J Dermatol</i> <i></i> <i></i> 159: 1 222-227<br/>

http://publicationslist.org/kamil.oender/refid4 2009-01-25T23:17:09Z

The yeast ribosome is composed of two subunits, the large 60S subunit (LSU) and the small 40S subunit (SSU) and harbors 78 ribosomal proteins (RPs), 59 of which are encoded by duplicate genes. Recently, deletions of the LSU paralogs RPL31A and RPL6B were found to increase significantly yeast replicative life span (RLS). RPs Rpl10 and Rps6 are known translational regulators. Here, we report that he...<br/><br/>Andreas Chiocchetti, Jia Zhou, Huashun Zhu, Thomas Karl, Olaf Haubenreisser, Mark Rinnerthaler, Gino Heeren, Kamil Oender, Johann Bauer, Helmut Hintner, Michael Breitenbach, Lore Breitenbach-Koller (2007) <i>Exp Gerontol</i> <i></i> <i></i> 42: 4 275-286<br/>

http://publicationslist.org/kamil.oender/refid13 2009-01-25T23:18:32Z

As global transcriptome analyses with a growing demand on layer-specific applications are widely used in cutaneous biology, we investigated the effect of established and optimized dermo-epidermal separation methods on the quality of RNA. We compared enzymatic separation with dispase, chemical separation with 1 M sodium chloride and heat separation to a treatment with 3.8% ammonium thioyanate. The ...<br/><br/>Andrea Trost, Johann W Bauer, Christoph Lanschützer, Martin Laimer, Michael Emberger, Helmut Hintner, Kamil Onder (2007) <i>Exp Dermatol</i> <i></i> <i></i> 16: 3 185-190<br/>

http://publicationslist.org/kamil.oender/refid5 2009-01-25T23:17:09Z

BACKGROUND: Azathioprine, in combination with corticosteroids, is the first-line therapy of severe forms of pemphigus vulgaris. Patients with an impaired thiopurine S-methyltransferase (TPMT) activity are at risk of developing severe myelo-suppression upon treatment with thiopurines such as azathioprine. Analysis of the TPMT status prior to drug administration is therefore highly recommended. Howe...<br/><br/>K Oender, C M Lanschuetzer, M Laimer, A Klausegger, B Paulweber, B Kofler, H Hintner, J W Bauer (2006) <i>J Eur Acad Dermatol Venereol</i> <i></i> <i></i> 20: 4 396-400<br/>

http://publicationslist.org/kamil.oender/refid3 2009-01-25T23:17:09Z

The yeast two-hybrid (Y2H) method is capable of delivering vast amounts of interacting positive yeast colonies from a single library screen, particularly if a multifunctional protein is used as bait. However, the selection of definitive colonies for further molecular analysis is limited by both technical practicality and high costs. Here we demonstrate a cost-effective and simple method for the ra...<br/><br/>K Oender, P Niedermayr, H Hintner, K Richter, L Koller, A Trost, J W Bauer, H Hundsberger (2006) <i>Assay Drug Dev Technol</i> <i></i> <i></i> 4: 6 709-719<br/>

http://publicationslist.org/kamil.oender/refid7 2009-01-25T23:17:09Z

M Laimer, J W Bauer, A Klausegger, J Koller, G Pohla-Gubo, W Muss, E Sadler, M Emberger, C M Lanschuetzer, R Hametner, V Wally, K Oender, H Hinter (2006) <i>Br J Dermatol</i> <i></i> <i></i> 154: 1 185-187<br/>

http://publicationslist.org/kamil.oender/refid6 2009-01-25T23:17:09Z

PURPOSE: Sequences within the non-coding 3'UTR (untranslated region) of genes were reported to be involved in the regulation of gene expression by modifying pathways of (co)transcription, post-transcriptional processing and RNA transport. However, direct biological evidence (i.e., knock-out models) is sparse. This report intends to correlate the first reported alteration within the 3'UTR of the C1...<br/><br/>Martin Laimer, Alfred Klausegger, Werner Aberer, Kamil Oender, Mathias Steinhuber, Christoph M Lanschuetzer, Verena Wally, Helmut Hintner, Johann W Bauer (2006) <i>Genet Med</i> <i></i> <i></i> 8: 4 249-254<br/>

http://publicationslist.org/kamil.oender/refid8 2009-01-25T23:17:09Z

Functional ribosomes synthesize proteins in all living cells and are composed of two labile associated subunits, which are made of rRNA and ribosomal proteins. The rRNA of the small 40S subunit (SSU) of the functional eukaryotic 80S ribosome decodes the mRNA molecule and the large 60S subunit (LSU) rRNA catalyzes protein synthesis. Recent fine structure determinations of the ribosome renewed inter...<br/><br/>Karin Pachler, Thomas Karl, Kerstin Kolmann, Norbert Mehlmer, Michaela Eder, Michael Loeffler, Kamil Oender, Elisabeth O Hochleitner, Friedrich Lottspeich, Nikolaus Bresgen, Klaus Richter, Michael Breitenbach, Lore Koller (2004) <i>FEMS Yeast Res</i> <i></i> <i></i> 5: 3 271-280<br/>

http://publicationslist.org/kamil.oender/refid9 2009-01-25T23:17:09Z

Biogenesis of an active ribosome complement and a dynamic cell surface complement are two major determinants of cellular growth. In yeast, the 60S ribosomal subunit protein RpL10p/Grc5p functions during successive stages in ribosome biogenesis, specifically rRNA processing, nucle(ol)ar preribosomal subunit assembly, nucleo-cytoplasmic transport and cytoplasmic maturation of ribosomes. Here, we rep...<br/><br/>Kamil Oender, Michael Loeffler, Edith Doppler, Michaela Eder, Sibylle Lach, Felix Heinrich, Thomas Karl, Roland Moesl, Harald Hundsberger, Torsten Klade, Peter Eckl, J Richard Dickinson, Michael Breitenbach, Lore Koller (2003) <i>Yeast</i> <i></i> <i></i> 20: 4 281-294<br/>

http://publicationslist.org/kamil.oender/refid14 2009-01-25T23:18:32Z

The yeast gene, GRC5 (growth control), is a member of the highly conserved QM gene family, the human member of which has been associated with the suppression of Wilms' tumor. GRC5 encodes ribosomal protein L10, which is thought to play a regulatory role in the translational control of gene expression. A revertant screen identified four spontaneous revertants of the mutant grc5-1ts allele. Genetic ...<br/><br/>T Karl, K Onder, R Kodzius, A Pichová, H Wimmer, A Th r, H Hundsberger, M Löffler, T Klade, A Beyer, M Breitenbach, L Koller (1999) <i>Curr Genet</i> <i></i> <i></i> 34: 6 419-429<br/>