http://publicationslist.org/data/mira.katan/atom.xml Mira Katanhttp://publicationslist.org/mira.katan$basepathfavicon.icoRecent additions to Mira Katan's PublicationsList.org pagehttp://publicationslist.org/publications.png2013-04-08T10:45:35Z http://publicationslist.org/mira.katan/refid23 2013-04-08T10:42:25Z

Grading of patients with aneurysmal subarachnoid hemorrhage (aSAH) is often confounded by seizure, hydrocephalus or sedation and the prediction of prognosis remains difficult. Recently, copeptin has been identified as a serum marker for outcomes in acute ischemic stroke and intracerebral hemorrhage (ICH). We investigated whether copeptin might serve as a marker for severity and prognosis in aSAH.<br/><br/>Christian Fung, Gian Marco De Marchis, Mira Katan, Marleen Seiler, Marcel Arnold, Jan Gralla, Andreas Raabe, Jürgen Beck (2013) <i>PLoS One</i> <i></i> <i></i> 8: 1 <br/>

http://publicationslist.org/mira.katan/refid21 2013-04-08T10:42:25Z

We hypothesized that infectious burden (IB), a composite serologic measure of exposure to common pathogens (i.e., Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus 1 and 2) associated with vascular risk in the prospective Northern Manhattan Study (NOMAS), would also be associated with cognition.<br/><br/>Mira Katan, Yeseon Park Moon, Myunghee Cho Paik, Ralph L Sacco, Clinton B Wright, Mitchell S V Elkind (2013) <i>Neurology</i> <i></i> <i></i> 80: 13 1209-1215<br/>

http://publicationslist.org/mira.katan/refid22 2013-04-08T10:42:25Z

OBJECTIVE: To evaluate and validate the incremental value of copeptin in the prediction of outcome and complications as compared with established clinical variables. METHODS: In this prospective, multicenter, cohort study, we measured copeptin in the emergency room within 24 hours from symptom onset in 783 patients with acute ischemic stroke. The 2 primary end points were unfavorable functional ou...<br/><br/>Gian Marco De Marchis, Mira Katan, Anja Weck, Felix Fluri, Christian Foerch, Oliver Findling, Philipp Schuetz, Daniela Buhl, Marwan El-Koussy, Henrik Gensicke, Marlen Seiler, Nils Morgenthaler, Heinrich P Mattle, Beat Mueller, Mirjam Christ-Crain, Marcel Arnold (2013) <i>Neurology</i> <i></i> <i></i> 80: 14 1278-1286<br/>

http://publicationslist.org/mira.katan/refid17 2012-08-10T16:58:36Z

The aim of this study was to determine the prognostic significance of microbleeds in TIA-patients. In patients with a transient ischaemic attack (TIA), the prognostic value of microbleeds is unknown.<br/><br/>F Fluri, F Jax, M Amort, S G Wetzel, P A Lyrer, M Katan, F Hatz, S T Engelter (2012) <i>Eur J Neurol</i> <i></i> <i></i> 19: 3 522-524<br/>

http://publicationslist.org/mira.katan/refid19 2012-11-22T15:23:45Z

RATIONALE: Copeptin independently predicts functional outcome and mortality at 90 days and one-year after ischemic stroke. In patients with transient ischemic attack, elevated copeptin values indicate an increased risk of further cerebrovascular events. AIMS: The Copeptin Risk Stratification (CoRisk) study aims to validate the predictive value of copeptin in patients with ischemic stroke and tra...<br/><br/>Gian Marco De Marchis, Mira Katan, Anja Weck, Caspar Brekenfeld, Heinrich P Mattle, Daniela Buhl, Beat Müller, Mirjam Christ-Crain, Marcel Arnold (2012) <i>Int J Stroke</i> <i></i> <i></i> : <br/>

http://publicationslist.org/mira.katan/refid20 2013-04-08T10:42:25Z

Early predictors for the development of stroke-associated infection may identify patients at high risk and reduce post-stroke infection and mortality.<br/><br/>Felix Fluri, Nils G Morgenthaler, Beat Mueller, Mirjam Christ-Crain, Mira Katan (2012) <i>PLoS One</i> <i></i> <i></i> 7: 10 <br/>

http://publicationslist.org/mira.katan/refid1 2012-08-10T16:59:23Z

The risk of stroke after a transient ischaemic attack (TIA) can be predicted by scores incorporating age, blood pressure, clinical features, duration (ABCD-score), and diabetes (ABCD2-score). However, some patients have strokes despite a low predicted risk according to these scores. We designed the ABCDE+ score by adding the variables 'etiology' and ischaemic lesion visible on diffusion-weighted i...<br/><br/>S T Engelter, M Amort, F Jax, F Weisskopf, M Katan, A Burow, L H Bonati, F Hatz, S G Wetzel, F Fluri, P A Lyrer (2012) <i>Eur J Neurol</i> <i></i> <i></i> 19: 1 55-61<br/>

http://publicationslist.org/mira.katan/refid4 2011-07-13T20:32:10Z

Early and accurate prediction of outcome in acute stroke is important and influences risk-optimized therapeutic strategies. Endocrine alterations of the hypothalamic-pituitary axis are amongst the first measurable alterations after cerebral ischaemia. We therefore evaluated the prognostic value of cortisol, triiodothyronine (T3), free thyroxine (fT4), thyroid-stimulating hormone (TSH) and growth h...<br/><br/>S Neidert, M Katan, P Schuetz, F Fluri, A Ernst, R Bingisser, L Kappos, S T Engelter, A Steck, B Müller, M Christ-Crain (2011) <i>J Intern Med</i> <i></i> <i></i> 269: 4 420-432<br/>

http://publicationslist.org/mira.katan/refid3 2011-05-16T20:51:46Z

TIA is a strong predictor of subsequent stroke. The hypothalamic stress hormone copeptin is an accurate prognostic marker in acute ischemic stroke. This study assessed prognostic reliability of 2 distinct stress hormones, copeptin and cortisol, for the risk stratification of re-events in patients with TIA.<br/><br/>M Katan, N Nigro, F Fluri, P Schuetz, N G Morgenthaler, F Jax, S Meckel, A Gass, R Bingisser, A Steck, L Kappos, S Engelter, B Müller, M Christ-Crain (2011) <i>Neurology</i> <i></i> <i></i> 76: 6 563-566<br/>

http://publicationslist.org/mira.katan/refid2 2012-08-10T16:59:23Z

Stroke is the third leading cause of mortality in the USA and one of the leading causes of severe morbidity. It is important to provide stroke patients and physicians with the most accurate prognostic information to optimize care and allocation of healthcare resources. Reliable prognostic markers available during the initial phase after acute stroke may aid clinical decision-making. Several intere...<br/><br/>Mira Katan, Mitchell S V Elkind (2011) <i>Expert Rev Neurother</i> <i></i> <i></i> 11: 2 225-239<br/>

http://publicationslist.org/mira.katan/refid13 2012-01-27T23:48:11Z

The Mannose-binding lectin (MBL) pathway of complement plays a pivotal role in the pathogenesis of ischemia/reperfusion (I/R) injury after experimental ischemic stroke. As comparable data in human ischemic stroke are limited, we investigated in more detail the association of MBL deficiency with infarction volume and functional outcome in a large cohort of patients receiving intravenous thrombolysi...<br/><br/>Michael Osthoff, Mira Katan, Felix Fluri, Philipp Schuetz, Roland Bingisser, Ludwig Kappos, Andreas J Steck, Stefan T Engelter, Beat Mueller, Mirjam Christ-Crain, Marten Trendelenburg (2011) <i>PLoS One</i> <i></i> <i></i> 6: 6 <br/>

http://publicationslist.org/mira.katan/refid14 2012-08-10T16:59:23Z

There is insufficient evidence regarding which clinical features are best suited to distinguish between transient ischemic attack (TIA) and disorders mimicking TIA (TIA mimics).<br/><br/>Margareth Amort, Felix Fluri, Juliane Schäfer, Florian Weisskopf, Mira Katan, Annika Burow, Heiner C Bucher, Leo H Bonati, Philippe A Lyrer, Stefan T Engelter (2011) <i>Cerebrovasc Dis</i> <i></i> <i></i> 32: 1 57-64<br/>

http://publicationslist.org/mira.katan/refid15 2011-07-13T20:36:22Z

Cardiac embolism is an important etiology of cerebrovascular ischaemic events (CIE). Echocardiography is routinely performed in patients with CIE despite guidelines recommending restriction of echocardiography to patients with clinically suspected cardioembolism.<br/><br/>M Wachter, M Katan, S Muzzarelli, A Rohner, M Christ-Crain, F Fluri, A M Bernheim (2011) <i>Eur J Neurol</i> <i></i> <i></i> 18: 6 925-928<br/>

http://publicationslist.org/mira.katan/refid16 2012-11-22T15:23:45Z

Sodium imbalance is common in-hospital electrolyte disturbance and is largely related to inequalities in water homeostasis. An important mechanism leading to dysnatraemic disorders is inadequately secreted plasma arginine vasopressin (AVP). Unfortunately, AVP measurement is cumbersome and not reliable. Copeptin is secreted in an equimolar ratio to AVP and is a promising marker in the differential ...<br/><br/>Nicole Nigro, Beat Müller, Nils G Morgenthaler, Felix Fluri, Philipp Schütz, Stefanie Neidert, Daiana Stolz, Roland Bingisser, Michael Tamm, Mirjam Christ-Crain, Mira Katan (2011) <i>Swiss Med Wkly</i> <i></i> <i></i> 141: <br/>

http://publicationslist.org/mira.katan/refid18 2012-01-27T23:48:11Z

Endocrine alterations of the hypothalamic-pituitary-axis are one of the first measurable physiological changes in cerebral insults. During acute stress, human growth hormone (GH) is stimulated and has shown to have a prognostic value in various diseases. Within this pilot study, we evaluated the prognostic value of GH in patients with acute intracerebral hemorrhage (ICH).<br/><br/>Christian Zweifel, Mira Katan, Philipp Schuetz, Andrea Ernst, Luigi Mariani, Beat Müller, Mirjam Christ-Crain (2011) <i>Biomarkers</i> <i></i> <i></i> 16: 6 511-516<br/>

http://publicationslist.org/mira.katan/refid5 2011-05-16T20:51:46Z

Stress is defined as anything that throws the body out of homeostatic balance; for example an acute illness. Any stressor which activates the hypothalamo-pituitary-adrenal (HPA) axis leads to an increase in concentrations of the adrenal stress hormone, cortisol. One of the major hypothalamic stress hormones, which is stimulated by different stressors, is vasopressin (AVP). However, measurement of ...<br/><br/>M Katan, M Christ-Crain (2010) <i>Swiss Med Wkly</i> <i></i> <i></i> 140: <br/>

http://publicationslist.org/mira.katan/refid6 2011-05-16T20:51:46Z

The purpose of this study was to examine the prognostic value of midregional pro-atrial natriuretic peptide (MR-proANP) in patients with acute ischemic stroke.<br/><br/>Mira Katan, Felix Fluri, Philipp Schuetz, Nils G Morgenthaler, Christian Zweifel, Roland Bingisser, Ludwig Kappos, Andreas Steck, Stefan T Engelter, Beat Müller, Mirjam Christ-Crain (2010) <i>J Am Coll Cardiol</i> <i></i> <i></i> 56: 13 1045-1053<br/>

http://publicationslist.org/mira.katan/refid7 2011-05-16T20:52:42Z

An accurate long-term outcome prediction may improve management of stroke patients. We investigated the ability of copeptin to predict 1-year outcome in stroke patients.<br/><br/>Sandrine A Urwyler, Philipp Schuetz, Felix Fluri, Nils G Morgenthaler, Christian Zweifel, Andreas Bergmann, Roland Bingisser, Ludwig Kappos, Andreas Steck, Stefan Engelter, Beat Müller, Mirjam Christ-Crain, Mira Katan (2010) <i>Stroke</i> <i></i> <i></i> 41: 7 1564-1567<br/>

http://publicationslist.org/mira.katan/refid8 2011-05-16T20:52:42Z

Spontaneous intracerebral hemorrhage (ICH) accounts for a high mortality and morbidity. Early prediction of outcome is crucial for optimized care and treatment decision. Copeptin, the C-terminal part of provasopressin, has emerged as a new prognostic marker in a variety of diseases, but its prognostic value in ICH is unknown.<br/><br/>Christian Zweifel, Mira Katan, Philipp Schuetz, Martin Siegemund, Nils G Morgenthaler, Adrian Merlo, Beat Mueller, Mirjam Christ-Crain (2010) <i>BMC Neurol</i> <i></i> <i></i> 10: <br/>

http://publicationslist.org/mira.katan/refid9 2011-05-16T20:52:42Z

Early prediction of outcome in patients with ischemic stroke is important. Vasopressin is a stress hormone. Its production rate is mirrored in circulating levels of copeptin, a fragment of provasopressin. We evaluated the prognostic value of copeptin in acute stroke patients.<br/><br/>Mira Katan, Felix Fluri, Nils G Morgenthaler, Philipp Schuetz, Christian Zweifel, Roland Bingisser, Klaus Müller, Stephan Meckel, Achim Gass, Ludwig Kappos, Andreas J Steck, Stefan T Engelter, Beat Müller, Mirjam Christ-Crain (2009) <i>Ann Neurol</i> <i></i> <i></i> 66: 6 799-808<br/>

http://publicationslist.org/mira.katan/refid11 2011-05-16T20:52:42Z

The study conducted by Seligman and coworkers included in the previous issue of Critical Care demonstrates that copeptin is a promising marker to predict outcome in patients with ventilator-associated pneumonia. In recent years, copeptin has emerged as a new prognostic marker in a variety of diseases, such as sepsis, community-acquired pneumonia, chronic obstructive pulmonary failure, heart failur...<br/><br/>Mira Katan, Beat Müller, Mirjam Christ-Crain (2008) <i>Crit Care</i> <i></i> <i></i> 12: 2 <br/>

http://publicationslist.org/mira.katan/refid10 2011-05-16T20:52:42Z

During stress, vasopressin is a potent synergistic factor of CRH as a hypothalamic stimulator of the HPA axis. The measurements of CRH and vasopressin levels are cumbersome because of their instability and short half-life. Copeptin is a more stable peptide stoichiometrically released from the same precursor molecule. The aim of our study was to compare copeptin and cortisol levels in different str...<br/><br/>Mira Katan, Nils Morgenthaler, Isabelle Widmer, Jardena J Puder, Caroline König, Beat Müller, Mirjam Christ-Crain (2008) <i>Neuro Endocrinol Lett</i> <i></i> <i></i> 29: 3 341-346<br/>

http://publicationslist.org/mira.katan/refid12 2011-05-16T20:52:42Z

Posterior pituitary function in patients with suspected diabetes insipidus is usually assessed by a water deprivation test. Alternatively, a nonosmotic stimulus such as hypoglycemia may be used to stimulate vasopressin [arginine vasopressin (AVP)] secretion. Plasma AVP measurement may aid in the diagnosis and, especially, differential diagnosis of diabetes insipidus and polydipsia. However, AVP me...<br/><br/>Mira Katan, Nils G Morgenthaler, Kashinath C S Dixit, Jonas Rutishauser, Georg E Brabant, Beat Müller, Mirjam Christ-Crain (2007) <i>J Clin Endocrinol Metab</i> <i></i> <i></i> 92: 7 2640-2643<br/>