http://publicationslist.org/data/nenad.bukvic/atom.xml Nenad Bukvichttp://publicationslist.org/nenad.bukvic$basepathfavicon.icoRecent additions to Nenad Bukvic's PublicationsList.org pagehttp://publicationslist.org/publications.png2010-06-26T09:20:56Z http://publicationslist.org/nenad.bukvic/refid2 2010-06-26T09:17:23Z

We have analyzed the frequency of premature centromeric division (PCD) in medical personnel professionally exposed to low doses of radiation. They had chromosome aberrations (CAs) involving dicentric chromosomes, ring chromosomes, acentric fragments, chromosome breaks, and chromatid breaks. The study included 30 exposed subjects and 23 controls who were each analyzed by a conventional cytogenetics...<br/><br/>Dubravka Jovicić, Snezana Milacić, Tanja D Vukov, Boban Rakić, Milena Stevanović, Danijela Drakulić, Rada Rakić, Nenad Bukvić (2010) <i>Health Phys</i> <i></i> <i></i> 98: 5 717-727<br/>

http://publicationslist.org/nenad.bukvic/refid1 2010-06-26T09:17:23Z

X;Y translocation is a relatively rare event in humans. Analyzed cytogenetically, the majority of these aberrations have breakpoints at Xp22 and Yq11. Females with t(X;Y)(p22;q11) are phenotypically normal except for short stature, while the males may have abnormalities. Aberrations that lead to nullisomy of the deleted region and complete loss of the respective genes have been recognized as a cau...<br/><br/>N Bukvic, V Delli Carri, M L Di Cosola, G Pustorino, C Cesarano, M Chetta, R Santacroce, M Sarno, F Sessa, V Longo, A Novelli, M Gentile, M Margaglione (2010) <i>Am J Med Genet A</i> <i></i> <i></i> 152A: 7 1730-1734<br/>

http://publicationslist.org/nenad.bukvic/refid7 2010-06-26T09:17:23Z

A few considerations, which we found in the literature, inspired us to reevaluate patients previously investigated [characterized for beta-thalassemia (beta-thal) and hereditary hemochromatosis (HH) genes] by our department at Medical Genetics, School of Medicine, University of Foggia, Italy.<br/><br/>Nenad Bukvic, Filomena Sportelli, Francesco Sessa, Vittoria Longo, Maria Grazia Roberti, Rosa Santacroce, Maurizio Margaglione (2009) <i>Hemoglobin</i> <i></i> <i></i> 33: 2 155-157<br/>

http://publicationslist.org/nenad.bukvic/refid6 2010-06-26T09:17:23Z

Occupational exposure to low doses of ionizing radiation is a particularly delicate subject for investigation, due to the cumulative effects of chronic exposure. It is extremely important to consider and to measure the biological response to given conditions of exposure. The aim of this study was to establish possible recovery from DNA damage in subjects professionally exposed to radiation in thei...<br/><br/>Dubravka Jovicic, Snezana Milacic, Natasa Milic, Nenad Bukvic, Tanja D Vukov (2009) <i>J Environ Pathol Toxicol Oncol</i> <i></i> <i></i> 28: 1 75-82<br/>

http://publicationslist.org/nenad.bukvic/refid5 2010-06-26T09:17:23Z

An 8-year-old boy was diagnosed with autism, along with development delay, seizures, and hypoplastic corpus callosum. His karyotype was 47, XY, +mar.ish (15) (D15Z1+, SNRPN+, GABRB3+, PML-(de novo?). The supernumerary marker chromosome 15 with euchromatin was monosatellited and monocentric. Although autism, seizures, and mental and developmental retardation are not rare in association with a dicen...<br/><br/>Jadranka D Jovanović-Privrodski, Ivana I Kavecan, Milan R Obrenović, Lucia A Buonadonna, Nenad M Bukvić (2009) <i>Pediatr Neurol</i> <i></i> <i></i> 41: 1 65-67<br/>

http://publicationslist.org/nenad.bukvic/refid4 2010-06-26T09:17:23Z

OBJECTIVE: To evaluate the variation of some biomarkers related to the level of enzymatic activity dependent on the different polymorphisms. METHODS: We studied 27 butadiene-exposed workers and 37 controls using different biomarkers of the genotoxic effect. The genotypes were determined using polymerase chain reaction and restriction fragment length polymorphism-polymerase chain reaction technique...<br/><br/>Nenad Bukvic, Piero Lovreglio, Margherita Fanelli, Francesco C Susca, Andrea Ballini, Patrizia Lastella, Vito Foà, Silvia Fustinoni, Leonardo Soleo, Ginevra Guanti (2009) <i>J Occup Environ Med</i> <i></i> <i></i> 51: 7 811-821<br/>

http://publicationslist.org/nenad.bukvic/refid3 2010-06-26T09:17:23Z

AIM: Hemophilia A is an X-linked bleeding disorder caused by mutations widespread in the human coagulation F8 gene. Apart from common intrachromosomal translocations, most of the mutations in the F8 gene are detectable using genomic sequencing analysis. However, deletions of one or more exons or deletion encompassing the entire gene can go undetected, especially in heterozygous females. RESULTS: T...<br/><br/>Rosa Santacroce, Vittoria Longo, Valeria Bafunno, Francesco Sessa, Massimiliano Chetta, Michelina Sarno, Nenad Bukvic, Giovanna D'Andrea, Michela Tomaiuolo, Maurizio Margaglione (2009) <i>Genet Test Mol Biomarkers</i> <i></i> <i></i> 13: 5 573-576<br/>

http://publicationslist.org/nenad.bukvic/refid9 2010-06-26T09:17:23Z

Marilena C Di Giacomo, Francesco C Susca, Nicoletta Resta, Nenad Bukvic, Antonella Vimercati, Ginevra Guanti (2007) <i>Am J Med Genet A</i> <i></i> <i></i> 143: 5 518-520<br/>

http://publicationslist.org/nenad.bukvic/refid8 2010-06-26T09:17:23Z

In a previously published article (Resta et al., 2006) on Robert's syndrome in prenatal diagnosis, a case of a 36-year-old woman and her 36-year-old, nonconsanguineous husband were presented. Our findings suggest the existence of nonsense mediated decay (NMD) variability which could account for the varying severity reported in carriers of identical mutations. Furthermore, fetal cells were used to ...<br/><br/>Nenad Bukvic, Nicoletta Resta, Dragoslav Bukvic, Francesco C Susca, Rosanna Bagnulo, Margherita Fanelli, Ginevra Guanti (2007) <i>Twin Res Hum Genet</i> <i></i> <i></i> 10: 4 655-657<br/>

http://publicationslist.org/nenad.bukvic/refid10 2010-06-26T09:17:23Z

Roberts syndrome (RS) is a rare disorder characterized by tetraphocomelia and several other clinical features. Cells from RS patients exhibit characteristic premature separation of heterochromatic region of many chromosomes and abnormalities in cell cycle. Mutations in the ESCO2 gene have recently been identified in 20 RS families. We performed mutational analysis of the ESCO2 gene in two fetuses ...<br/><br/>Nicoletta Resta, Francesco Claudio Susca, Marilena C Di Giacomo, Alessandro Stella, Nenad Bukvic, Rosanna Bagnulo, Cristiano Simone, Ginevra Guanti (2006) <i>J Cell Physiol</i> <i></i> <i></i> 209: 1 67-73<br/>

http://publicationslist.org/nenad.bukvic/refid11 2010-06-26T09:18:07Z

1,3-Butadiene (BD), a probable carcinogen to humans, has been shown to have an ill-defined genotoxicity in occupationally exposed workers. In the present study, the influence of exposure to very low doses of BD and to cigarette smoking was investigated on some cytogenetic endpoints, namely, sister chromatid exchanges (SCE), chromosomal aberrations (CA) and cells with a high frequency of SCE (HFC),...<br/><br/>Piero Lovreglio, Nenad Bukvic, Silvia Fustinoni, Andrea Ballini, Ignazio Drago, Vito Foà, Ginevra Guanti, Leonardo Soleo (2006) <i>Arch Toxicol</i> <i></i> <i></i> 80: 6 378-381<br/>

http://publicationslist.org/nenad.bukvic/refid12 2010-06-26T09:18:07Z

The detection of very rare variants in prenatal diagnosis often causes counseling difficulties and anxiety in parents. We describe a duplication of the proximal region of chromosome 9 short arm in two cases of prenatal diagnosis and in one young woman, with evidence that such rearrangement is an uncommon variant. The duplication was investigated using Fluorescence in situ hybridization (FISH). Alt...<br/><br/>Marilena C Di Giacomo, Carla Cesarano, Nenad Bukvic, Evangelia Manisali, Ginevra Guanti, Francesco Susca (2004) <i>Prenat Diagn</i> <i></i> <i></i> 24: 8 619-622<br/>

http://publicationslist.org/nenad.bukvic/refid14 2010-06-26T09:18:07Z

In the present study we analysed the possible effect of age, sex and smoking on the mean values of micronucleus (MN) and sister chromatid exchange (SCE) frequencies on peripheral blood obtained from 38 subjects ranging in age from 16 to 63 years and 16 centenarians. The mean number of binucleated cells with micronuclei varied in function of age and sex (as demonstrated by the analysis of covarianc...<br/><br/>N Bukvic, M Gentile, F Susca, M Fanelli, G Serio, L Buonadonna, A Capurso, G Guanti (2001) <i>Mutat Res</i> <i></i> <i></i> 498: 1-2 159-167<br/>

http://publicationslist.org/nenad.bukvic/refid13 2010-06-26T09:18:07Z

In the period from January 1980 until December 1990 we treated 147 children and adolescents with supracondylar humerus fracture, and followed the outcome in 127 of them. Three (2.4%) patients had no displacement of fractured bones and were treated only with plaster cast immobilization. Twenty three (18.1%) underwent closed reduction of fragments and application of a plaster cast. The majority (97;...<br/><br/>S Vuckov, A Kvesić, Z Rebac, D Cuculić, F Lovasić, N Bukvić (2001) <i>Coll Antropol</i> <i></i> <i></i> 25: 1 255-262<br/>

http://publicationslist.org/nenad.bukvic/refid16 2010-06-26T09:18:07Z

Although several studies have examined the effects on health of exposure to epichlorohydrin (ECH) through normal industrial operations and production, there is still considerable interest in its potential harmful effects on humans. The aim of the present study was to evaluate ECH effects in vitro through controlled investigations by using sister chromatid exchange (SCE), micronucleus (MN), and chr...<br/><br/>N Bukvic, P Bavaro, L Soleo, M Fanelli, I Stipani, G Elia, F Susca, G Guanti (2000) <i>Teratog Carcinog Mutagen</i> <i></i> <i></i> 20: 5 313-320<br/>

http://publicationslist.org/nenad.bukvic/refid17 2010-06-26T09:18:07Z

Oral contraceptives are highly efficient and easily administered drugs; however, it must not be forgotten that they are composed of chemical substances which can be classified as potential carcinogens. Testing of a substance for genotoxicity represents a reliable approach both to evaluate the genetic hazard and to obtain information on its possible tumorigenic (cancerogenic) properties. The presen...<br/><br/>N Bukvic, F Susca, D Bukvic, M Fanelli, G Guanti (2000) <i>Teratog Carcinog Mutagen</i> <i></i> <i></i> 20: 3 147-159<br/>

http://publicationslist.org/nenad.bukvic/refid15 2010-06-26T09:18:07Z

Tumors of large bowel continue to be one of the leading causes of morbidity and mortality with about 300,000 new cases and 200,000 deaths per year in Europe and USA despite recent technological advancements. In sharp contrast with these discouraging data, the basic knowledge of colorectal neoplasms has grown remarkably in the last decades especially with the genetic elucidation of the two inherite...<br/><br/>G Guanti, N Bukvić (2000) <i>Acta Chir Iugosl</i> <i></i> <i></i> 47: 4 Suppl 1 23-25<br/>

http://publicationslist.org/nenad.bukvic/refid18 2010-06-26T09:18:07Z

In the period between January 1980 and December 1990 we had applied the operative Lich-Gregoir antireflux method on 166 patients, all of whom were children and adolescents, and performed 275 antireflux surgical procedures. The application of the above mentioned method on our patients yielded a success of 97.8%. There have been no intraoperative complications which would affect the ultimate success...<br/><br/>S Vuckov, H Nikolić, A Kvesić, N Bukvić (1999) <i>Eur J Pediatr Surg</i> <i></i> <i></i> 9: 1 33-36<br/>

http://publicationslist.org/nenad.bukvic/refid20 2010-06-26T09:18:07Z

The Authors reported data of benzene concentrations obtained in Bari during period of time between 1990 and 1995; the measured levels of benzene concentrations are not in accord with referent values prescribed by the law, mostly always they are exceeded. Present study also discuss problems related to gasoline consumption and the number of cars in circulation.<br/><br/>F Cassano, P Bavaro, G De Marinis, N Bukvic, A Giacomantonio (1998) <i>G Ital Med Lav Ergon</i> <i></i> <i></i> 20: 2 91-97<br/>

http://publicationslist.org/nenad.bukvic/refid19 2010-06-26T09:18:07Z

Peripheral blood lymphocytes from 22 men with low average exposure (229 micrograms/m3 = 0.72 ppm) to benzene and 19 control men were investigated for Sister Chromatid Exchange (SCE) frequency. The majority of the men (21 exposed, 19 controls) were also investigated using the micronucleus assay (MN). The exposed subjects were employed at 10 different gas stations in or near the city (Bari/South Ita...<br/><br/>N Bukvic, P Bavaro, G Elia, F Cassano, M Fanelli, G Guanti (1998) <i>Mutat Res</i> <i></i> <i></i> 415: 1-2 25-33<br/>

http://publicationslist.org/nenad.bukvic/refid22 2010-06-26T09:18:33Z

Approximately 2 weeks after accidental overexposure to X-ray radiation, a worker developed acute radiodermatitis on fingers of both hands. Exposure simulation indicated that total ionizing radiation absorbed by his fingers amounted to about 20 Gy. After 2 years, acute radiodermatitis evolved to chronicity of lesions with presence of atrophic skin, teleangiectasia, alopecia, and dyskeratosis on thr...<br/><br/>L Soleo, A Basso, L Di Lorenzo, N Bukvic, N L'Abbate (1996) <i>Am J Ind Med</i> <i></i> <i></i> 30: 2 207-211<br/>

http://publicationslist.org/nenad.bukvic/refid21 2010-06-26T09:18:33Z

Chromosome aberrations, micronuclei, and sister chromatid exchanges (SCE) were evaluated in cultured lymphocytes of coke oven workers of an Italian steel industry plant, occupationally exposed to polycyclic aromatic hydrocarbons, and in a group of unexposed controls from a non-oven plant in the same area. No differences were found between exposed and controls for rates of total abnormal metaphases...<br/><br/>A Forni, G Guanti, N Bukvic, G Ferri, V Foà (1996) <i>Toxicol Lett</i> <i></i> <i></i> 88: 1-3 185-189<br/>

http://publicationslist.org/nenad.bukvic/refid23 2010-06-26T09:18:33Z

We describe an unusual marker chromosome Y. This marker is present in 5% of the lymphocytes of a dysgenetic woman showing a mosaic karyotype 45,X/46,XY/47,XY+mar. Q-banding revealed that the marker was morphologically identical to the Y chromosome of the patient but presented the primary constriction in the heterochromatic region. C-banding confirmed that the heterochromatic region was C-positive;...<br/><br/>N Bukvic, F Susca, M Gentile, E Tangari, A Ianniruberto, G Guanti (1996) <i>Hum Genet</i> <i></i> <i></i> 97: 4 453-456<br/>