http://publicationslist.org/data/pascal.seve/atom.xml Pascal Sevehttp://publicationslist.org/pascal.seve$basepathfavicon.icoRecent additions to Pascal Seve's PublicationsList.org pagehttp://publicationslist.org/publications.png2010-02-28T16:02:41Z http://publicationslist.org/pascal.seve/refid5 2010-02-28T15:59:22Z

Lung cancer is a leading cause of death among adults. Non-small cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancer cases. For more than half of all patients diagnosis does not occur until the disease has metastasised. At this advanced stage, the 5-year survival rate is just 15%. Platinum-based chemotherapy forms the backbone of treatment for patients with advanced NSCLC and...<br/><br/>Pascal Sève, Tony Reiman, Charles Dumontet (2010) <i>Lung Cancer</i> <i></i> <i></i> 67: 2 136-143<br/>

http://publicationslist.org/pascal.seve/refid3 2010-02-28T15:59:22Z

BACKGROUND: The natural history of multiple endocrine neoplasia type 1 (MEN1) is known through single-institution or single-family studies. We aimed to analyze the risk factors and causes of death in a large cohort of MEN1 patients. METHODS: Overall, 758 symptomatic MEN1 patients were identified through the GTE network (Groupe d'étude des Tumeurs Endocrines), which involves French and Belgian gen...<br/><br/>Pierre Goudet, Arnaud Murat, Christine Binquet, Christine Cardot-Bauters, Annie Costa, Philippe Ruszniewski, Patricia Niccoli, Fabrice Ménégaux, Georges Chabrier, Françoise Borson-Chazot, Antoine Tabarin, Philippe Bouchard, Brigitte Delemer, Alfred Beckers, Claire Bonithon-Kopp, C Ajzenberg, J J Altman, F Archambeaud, J R Attali, C Badet, J Barbier, M Barthet, E Baudin, B Bauduceau, P Bernades, X Bertagna, J Bertherat, P Boissel, P Bouchard, J M Boyaval, L Bresler, J F Bretagne, J Bringer, L Brunaud, J Burger, P Carenco, P Caron, B Cathebras, M Celerier, O Chabre, G Chabrier, D Chadenas, P Chanson, D Charitanski, J A Chayvialle, C Colmar Montiel, J M Comas, B Conte Devolx, A Cortot, E Cosson, P Cougard, P Cubertafond, P D'Anella, P Darsy, T Defechereux, F Delecourt, J Denis, C Derrien, D Dewailly, H du Boullay-Choplin, A S Dramais, C Droumaguet, C Dubost, F Duron, B Emperauger-Beauvais, P Emy, S Gauthier, A P Gimenez Roqueplo, B Goichot, D Goldfain, M Gosselin, I Guilhem, P J Guillausseau, P Hamon, J F Henry, P J Jaquet, V Kerlan, J M Khun, B Knebelmann, J L Kraimps, A Krivtzky, J D Lalau, P Lecomte, J J Legros, D Levoir, B Maizeray-Cailliau, D Malet, M Malinski, G Mantion, C Mathe, M Mathonnet, D Melliere, E H Metman, M Meurisse, R Modigliani, M Monsaigeon, C Naouri, C Oliver, F Olivier, J Orgiazzi, M Parneix, C Partenski, J L Peix, A Penfornis, A Pradignac, C Pouget, M Pugeat, M L Raffin-Sanson, M Rodier, P Roger, V Rohmer, P Rougier, H Rousset, J Roy, J L Sadoul, E Sarfati, J L Schlienger, M Schlumberger, P Seve, D Simon, O Soubrane, J C Soule, P Thieblot, C Thivolet, P Thomopoulos, G Turpin, P Valensi, M C Vantighem, M F Verger, B Verges, O Verier-Mine, E Verlet, B Vialettes, R Viard, S Walter, A Warnet, B Wechsler, J L Wemeau, G Weryha, B Woehl-Kremer (2010) <i>World J Surg</i> <i></i> <i></i> 34: 2 249-255<br/>

http://publicationslist.org/pascal.seve/refid2 2010-02-28T15:59:22Z

Background. Parvovirus B19 infection (PVB19) has been linked with a broad spectrum of clinical syndromes. In addition to erythema infectiosum and asymptomatic infection, other less common manifestations include transient aplastic crisis in patients with hemoglobinopathies, pure red cell aplasia and pancytopenia in immunocompromised persons, nonimmune hydrops fetalis, chronic arthritis, myocarditis...<br/><br/>Julie Le Scanff, Alain Vighetto, Yahia Mekki, Anh Minh Nguyen, Jean-François Dufour, Christiane Broussolle, Pascal Seve (2010) <i>Eur J Ophthalmol</i> <i></i> <i></i> : <br/>

http://publicationslist.org/pascal.seve/refid1 2010-02-28T15:59:22Z

INTRODUCTION: Hypereosinophilic syndromes rarely manifest as polyserositis. Imatinib mesylate is the reference treatment for myeloid variants of FIP1L1-PDGFRA-positive hypereosinophilic syndromes. A response to imatinib has also been reported in FIP1L1-PDGFRA-negative hypereosinophilic syndromes. CASE REPORT: We report a 25-year-old man who presented with a FIP1L1-PDGFRA-negative hypereosinophilic...<br/><br/>L Green, J-E Kahn, J-F Dufour, J Le Scanff, A Charhon, C Broussolle, P Sève (2010) <i>Rev Med Interne</i> <i></i> <i></i> : <br/>

http://publicationslist.org/pascal.seve/refid63 2010-02-28T15:59:22Z

BACKGROUND: Case reports and small short case series have described patients with sarcoidosis and melanoma. OBJECTIVES: To examine the relation between sarcoidosis and melanoma. METHODS: Computerized search of all patients seen at our department of dermatology between 1998 and 2007 and review of the literature using a Medline search from 1985 to June 2008. RESULTS: We identified 7 cases in our pop...<br/><br/>Pascal Seve, Anne Marie Schott, Michel Pavic, Christiane Broussolle, Lila Gilis, Luc Thomas (2009) <i>Dermatology</i> <i></i> <i></i> 219: 1 25-31<br/>

http://publicationslist.org/pascal.seve/refid10 2010-02-28T15:59:22Z

BACKGROUND: In 2002, the French Federation of Comprehensive Cancer Centers published clinical practice guidelines (CPGs) for the management of carcinomas of unknown primary (CUP). METHODS: A controlled "before-after" study at two centers (experimental in Lyon, France and control in Edmonton, Canada) to assess the impact of CPGs on CUP management. Fifty-CUP patients treated in 2000-2001, i.e. befor...<br/><br/>P Sève, J Mackey, M Sawyer, T Lesimple, C de La Fouchardière, C Broussolle, C Dumontet, I Ray-Coquard (2009) <i>Bull Cancer</i> <i></i> <i></i> 96: 4 E7-17<br/>

http://publicationslist.org/pascal.seve/refid12 2010-02-28T15:59:22Z

In developed countries, uveitis is quite common and chronic course is associated with a poor visual prognosis. However, no guidelines for their management have been consensually proposed. Based on the experience of ophthalmologists and internists from tertiary care centers, this article describes the management of uveitis, including the diagnostic procedure, indications and types of anti-inflammat...<br/><br/>S Abad, P Sève, R Dhote, A-P Brézin (2009) <i>Rev Med Interne</i> <i></i> <i></i> 30: 6 492-500<br/>

http://publicationslist.org/pascal.seve/refid64 2010-02-28T15:59:22Z

OBJECTIVE: To describe the prevalence, main characteristics, and treatment of severe autoimmune cytopenias [autoimmune hemolytic anemia (AIHA), autoimmune thrombocytopenic purpura (AITP)] in patients with chronic hepatitis C virus (HCV) infection. METHODS: Retrospective chart review of patients with chronic HCV infection seen at our institution. Two additional departments contributed eight more pa...<br/><br/>Jean-François Dufour, Pierre Pradat, Marc Ruivard, Arnaud Hot, Charles Dumontet, Christiane Broussolle, Christian Trepo, Pascal Sève (2009) <i>Eur J Gastroenterol Hepatol</i> <i></i> <i></i> 21: 3 245-253<br/>

http://publicationslist.org/pascal.seve/refid11 2010-02-28T15:59:22Z

BACKGROUND: Spinal cord involvement in sarcoidosis is rare, occurring in <1% of patients with sarcoidosis. METHODS: We report seven cases of spinal cord sarcoidosis, seen in two French hospitals over a 13-year period. Presentation of disease, methods of diagnosis and response to treatment, with quantification according to the reduction of the modified Rankin scale (MRS), were noted. RESULTS: Six p...<br/><br/>L Varron, C Broussolle, J-P Candessanche, R Marignier, H Rousset, J Ninet, P Sève (2009) <i>Eur J Neurol</i> <i></i> <i></i> 16: 3 289-296<br/>

http://publicationslist.org/pascal.seve/refid8 2010-02-28T15:59:22Z

BACKGROUND: We have investigated predictors of 90-day-mortality in a large cohort of non-specific cancer of unknown primary patients. METHODS: Predictors have been identified by univariate and then logistic regression analysis in a single-center cohort comprising 429 patients (development cohort). We identified four predictors that produced a predictive score that has been applied to an independen...<br/><br/>Nicolas Penel, Sylvie Negrier, Isabelle Ray-Coquard, Charles Ferte, Patrick Devos, Antoine Hollebecque, Michael B Sawyer, Antoine Adenis, Pascal Seve (2009) <i>PLoS One</i> <i></i> <i></i> 4: 8 <br/>

http://publicationslist.org/pascal.seve/refid4 2010-02-28T15:59:22Z

Hepatic angiosarcoma is a rare malignant vascular tumor, which accounts for up to 2% of all primary liver tumors. The most frequent symptoms on presentation are weight loss, weakness and abdominal pain. Diagnosis of diffuse hepatic angiosarcoma can be challenging. We report an original case of diffuse liver angiosarcoma revealed by haematological abnormalities initially diagnosed as an Evans syndr...<br/><br/>Julie Le Scanff, Stéphane Durupt, François Bailly, Agnès Rode, Pascal Sève (2009) <i>Cases J</i> <i></i> <i></i> 2: <br/>

http://publicationslist.org/pascal.seve/refid9 2010-02-28T15:59:22Z

PURPOSE: To assess the value of fluorine-18 fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) in patients with unexplained chronic uveitis. METHODS: Retrospective review of 19 (18)F-FDG PET scans. All patients had normal chest CT. In the final analysis, the authors used criteria similar to the criteria of Abad et al. (Abad S, Meyssonier V, Allali J, et al. Association of peripheral m...<br/><br/>Pascal Seve, Claire Billotey, Marc Janier, Jean-Daniel Grange, Christiane Broussolle, Laurent Kodjikian (2009) <i>Ocul Immunol Inflamm</i> <i></i> <i></i> 17: 3 179-184<br/>

http://publicationslist.org/pascal.seve/refid6 2010-02-28T15:59:22Z

Pascal Seve, Emeline Mennesson, Jean-Daniel Grange, Christiane Broussolle, Laurent Kodjikian (2009) <i>Acta Ophthalmol</i> <i></i> <i></i> : <br/>

http://publicationslist.org/pascal.seve/refid7 2010-02-28T15:59:22Z

Relapsing polychondritis is an episodic and progressive systemic inflammatory disease characterized by auricular chondritis, polyarthritis, nasal and respiratory tract chondritis. About 30% of the patients have additional autoimmune and or hematological diseases, most frequently systemic vasculitis, rheumatoid arthritis, myelodysplastic syndromes or systemic lupus erythematosus. So far, only one c...<br/><br/>Florian Pasquet, Vincent Cottin, Nadia Sivova, Julie Le Scanff, Christiane Broussolle, Pascal Sève (2009) <i>Rheumatol Int</i> <i></i> <i></i> : <br/>

http://publicationslist.org/pascal.seve/refid18 2010-02-28T15:59:22Z

Ectopic adrenocorticotropic (ACTH) syndrome is a rare condition, generally due to lung or carcinoid tumors. 18-fluorodeoxy-glucose positron emission tomography ((18)FDG-PET) can be useful where conventional localization techniques often fail. A 50-year-old man presented with sudden diffuse oedema, hypokaliemic alkalosis, Diabetes mellitus and high serum levels of ACTH and cortisol. Ectopic ACTH sy...<br/><br/>E Gomard-Mennesson, P Sève, E De La Roche, S Collardeau-Frachon, C Lombard-Bohas, C Broussolle (2008) <i>Rev Med Interne</i> <i></i> <i></i> 29: 9 751-753<br/>

http://publicationslist.org/pascal.seve/refid19 2010-02-28T15:59:22Z

On the basis of preclinical studies that show overexpression of class III beta-tubulin is associated with resistance to tubulin-binding agents, several investigators have addressed the relation between class III beta-tubulin and outcome in patients treated with such agents. High expression of class III beta-tubulin has been found to be correlated either with low response rates in patients treated ...<br/><br/>Pascal Sève, Charles Dumontet (2008) <i>Lancet Oncol</i> <i></i> <i></i> 9: 2 168-175<br/>

http://publicationslist.org/pascal.seve/refid20 2010-02-28T15:59:22Z

Our study aimed to determine the frequency of uveitis among MS patients through the Lyon MS Database and compare the clinical spectrum and time course of MS in patients with or without uveitis. Twenty-eight patients with uveitis were detected. The prevalence of uveitis in our population was 0.65% (28/4,300). Uveitis preceded onset of MS in 46% of the patients; it occurred simultaneously or after M...<br/><br/>Julie Le Scanff, Pascal Sève, Christel Renoux, Christiane Broussolle, Christian Confavreux, Sandra Vukusic (2008) <i>Mult Scler</i> <i></i> <i></i> 14: 3 415-417<br/>

http://publicationslist.org/pascal.seve/refid17 2010-02-28T15:59:22Z

INTRODUCTION: Cancer-related fatigue is very common but its management remains frustrating. We thus sought to review current knowledge in this field: epidemiologic data, pathophysiological mechanisms, assessment, and treatment. METHODS: We queried the Medline database for all articles on this topic published between 1997 and 2007 and analyzed the articles published in English and French, as well a...<br/><br/>Michel Pavic, Pascal Sève, Hugues Rousset, Philippe Debourdeau (2008) <i>Presse Med</i> <i></i> <i></i> 37: 6 Pt 1 957-966<br/>

http://publicationslist.org/pascal.seve/refid16 2010-02-28T15:59:22Z

AIM: To determine the prognostic value of microtubule component expression in tumors of patients with carcinomas of unknown primary site (CUP). PATIENTS AND METHODS: Class III beta-tubulin, Delta2-alpha-tubulin and tau protein were examined immunohistochemically in 51 CUP tumors from patients receiving paclitaxel and compared with their response to treatment. RESULTS: The overall response rate was...<br/><br/>Pascal Sève, Tony Reiman, Sylvie Isaac, Véronique Trillet-Lenoir, Laurence Lafanéchère, Michael Sawyer, Charles Dumontet (2008) <i>Anticancer Res</i> <i></i> <i></i> 28: 2B 1161-1167<br/>

http://publicationslist.org/pascal.seve/refid14 2010-02-28T15:59:22Z

P Sève, J Mackey, M Sawyer, T Lesimple, C de la Fouchardière, C Broussolle, C Dumontet, I Ray-Coquard (2008) <i>Clin Oncol (R Coll Radiol)</i> <i></i> <i></i> 20: 8 658-659<br/>

http://publicationslist.org/pascal.seve/refid13 2010-02-28T15:59:22Z

J Le Scanff, F Bailly, S Durupt, P Sève, M Ruivard (2008) <i>Rev Med Interne</i> <i></i> <i></i> 29: 10 840-845<br/>

http://publicationslist.org/pascal.seve/refid15 2010-02-28T15:59:22Z

To describe the main characteristics and treatment of autoimmune hemolytic anemia (AHA) in patients with common variable immunodeficiency (CVID), we analyzed data from 18 patients, 4 from an earlier study and 14 from the French DEF-I cohort on adult patients with primary hypogammaglobulinemia. To be included, patients had to have CVID and a previous history of AHA with a hemoglobin level < or =90 ...<br/><br/>Pascal Sève, Laure Bourdillon, Francoise Sarrot-Reynauld, Marc Ruivard, Rolland Jaussaud, Damien Bouhour, Bernard Bonotte, Martine Gardembas, Vincent Poindron, Marie-France Thiercelin, Christiane Broussolle, Eric Oksenhendler (2008) <i>Medicine (Baltimore)</i> <i></i> <i></i> 87: 3 177-184<br/>

http://publicationslist.org/pascal.seve/refid27 2010-02-28T15:59:22Z

BACKGROUND: The authors conducted a comprehensive review of the efficacy of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography (FDG-PET) in the detection of primary tumors in patients with disseminated carcinoma of unknown primary site. METHODS: Ten studies (involving a total of 221 patients) tat were published between 1998 and 2006 were reviewed. Each study evaluated the role of FDG-PE...<br/><br/>Pascal Sève, Claire Billotey, Christiane Broussolle, Charles Dumontet, John R Mackey (2007) <i>Cancer</i> <i></i> <i></i> 109: 2 292-299<br/>

http://publicationslist.org/pascal.seve/refid28 2010-02-28T15:59:22Z

Granulomatous myositis (GM) is a rare condition that has generally been described in association with sarcoidosis. In the absence of sarcoidosis or other underlying disease, a diagnosis of isolated GM is considered. Only one study has focused on the clinical difference between isolated GM and sarcoid myopathy (SM). We report 13 cases of symptomatic GM; 8 had sarcoidosis. All patients with sarcoido...<br/><br/>Karine Le Roux, Nathalie Streichenberger, Christophe Vial, Philippe Petiot, Leonard Feasson, Françoise Bouhour, Jacques Ninet, Florence Lachenal, Christiane Broussolle, Pascal Sève (2007) <i>Muscle Nerve</i> <i></i> <i></i> 35: 2 171-177<br/>

http://publicationslist.org/pascal.seve/refid32 2010-02-28T15:59:22Z

P Sève, E Lanier-Gachon, V Garbit, K Stankovic, V Lapras, C Broussolle (2007) <i>Rev Med Interne</i> <i></i> <i></i> 28: 2 120-121<br/>

http://publicationslist.org/pascal.seve/refid25 2010-02-28T15:59:22Z

INTRODUCTION: Granulomatous myositis is a rare condition that has been described in association with sarcoidosis. In the absence of sarcoidosis or other underlying disease, a diagnosis of isolated granulomatous myositis is considered. OBSERVATION: A 61-year-old African man presented with progressive limitation in running and proximal atrophy of the lower limbs for the past year. Quadricipital musc...<br/><br/>J-F Dufour, C Billotey, N Streichenberger, F Bouhour, C Broussolle, P Sève (2007) <i>Rev Med Interne</i> <i></i> <i></i> 28: 8 568-570<br/>

http://publicationslist.org/pascal.seve/refid30 2010-02-28T15:59:22Z

PURPOSE: In this study, we determine the prevalence and the prognostic value of the class III beta-tubulin microtubule protein examined immunohistochemically, in tumors of 40 patients with carcinomas of unknown primary site treated with paclitaxel-based chemotherapy. METHODS: Immunohistochemical intensity of staining and percentage of cells were quantified. Clinical characteristics, response to ch...<br/><br/>Pascal Sève, Tony Reiman, Raymond Lai, John Hanson, Cheryl Santos, Lorelei Johnson, Laith Dabbagh, Michael Sawyer, Charles Dumontet, John R Mackey (2007) <i>Cancer Chemother Pharmacol</i> <i></i> <i></i> 60: 1 27-34<br/>

http://publicationslist.org/pascal.seve/refid26 2010-02-28T15:59:22Z

PURPOSE: High class III beta-tubulin (bTubIII) expression in advanced non-small cell lung cancer is known to correlate with reduced response rates and inferior survival with anti-microtubule agents. JBR.10 showed a 12% and 15% improvement in 5-year recurrence-free survival (RFS) and overall survival (OS), respectively, with the addition of cisplatin and vinorelbine following resection of stage IB-...<br/><br/>Pascal Sève, Raymond Lai, Keyue Ding, Timothy Winton, Charles Butts, John Mackey, Charles Dumontet, Laith Dabbagh, Sarit Aviel-Ronen, Lesley Seymour, Marlo Whitehead, Ming-Sound Tsao, Frances A Shepherd, Tony Reiman (2007) <i>Clin Cancer Res</i> <i></i> <i></i> 13: 3 994-999<br/>

http://publicationslist.org/pascal.seve/refid21 2010-02-28T15:59:22Z

BACKGROUND: Kawasaki-like syndrome (KLS) is rare in adults; one third of these patients are infected by Human immunodeficiency virus (HIV). Our study reports cases of KLS occurring in HIV-positive adults and reviews the literature to compare their characteristics with HIV-negative adults and children with Kawasaki disease (KD). METHODS: Report of cases and review of the literature. RESULTS: Amongs...<br/><br/>K Stankovic, P Miailhes, D Bessis, T Ferry, C Broussolle, P Sève (2007) <i>J Infect</i> <i></i> <i></i> 55: 6 488-494<br/>

http://publicationslist.org/pascal.seve/refid23 2010-02-28T15:59:22Z

OBJECTIVE: An unusual case of a patient with Löfgren syndrome peritoneal involvement by sarcoidosis. Patient and methods: A 36-year-old woman presented with Löfgren syndrome and an increase in liver enzyme levels. An abdominal CT scan showed multiple nodules on the peritoneum mimicking peritoneal carcinomatosis. Laparoscopy was conducted with biopsy of the peritoneal nodules. RESULTS: Biopsy spe...<br/><br/>Laure Bourdillon, Emilie Lanier-Gachon, Katia Stankovic, Brigitte Bancel, Véronique Lapras, Christiane Broussolle, Pascal Sève (2007) <i>Chest</i> <i></i> <i></i> 132: 1 310-312<br/>

http://publicationslist.org/pascal.seve/refid22 2010-02-28T15:59:22Z

We present the case of a 79-year-old female patient with chronic obstructive pulmonary disease on home oxygen therapy who was diagnosed as having Sjögren's syndrome with arthralgias and painful sensory neuropathy. She subsequently developed bilateral numb chin syndrome. Because of refractory and disabling symptoms under high corticosteroids and severe chronic obstructive pulmonary disease, we dec...<br/><br/>Pascal Sève, Emilie Gachon, Philippe Petiot, Katia Stankovic, Annick Charhon, Christiane Broussolle (2007) <i>Rheumatol Int</i> <i></i> <i></i> 28: 2 175-177<br/>

http://publicationslist.org/pascal.seve/refid24 2010-02-28T15:59:22Z

Pseudoxanthoma elasticum (PXE) is a heritable connective tissue disorder affecting the elastic structures in the body, manifesting with cutaneous, ophthalmologic and cardiovascular findings. The association of PXE and systemic disease is rare, as only six cases have been reported in the literature. We describe herein two cases of coexisting PXE and cutaneous lupus and discuss a possible associatio...<br/><br/>Julie Le Scanff, Pascal Sève, Stephane Dalle, Laurent Kodjikian, Luc Thomas, Christiane Broussolle (2007) <i>Int J Dermatol</i> <i></i> <i></i> 46: 6 622-624<br/>

http://publicationslist.org/pascal.seve/refid34 2010-02-28T15:59:22Z

Michel Pavic, Pierre Moncharmont, Pascal Sève, Dominique Rigal, Christiane Broussolle (2006) <i>Gastroenterol Clin Biol</i> <i></i> <i></i> 30: 5 797-798<br/>

http://publicationslist.org/pascal.seve/refid35 2010-02-28T15:59:22Z

The aim of this study was to evaluate the response to treatment and the long-term outcome in a cohort of patients in whom severe autoimmune hemolytic anaemia (AHA) was the leading manifestation of systemic lupus erythematosus (SLE). Twenty-six women with severe isolated AHA were included. Corticosteroids were used as the initial treatment for all patients in our study. An initial response was obta...<br/><br/>E Gomard-Mennesson, M Ruivard, M Koenig, A Woods, N Magy, J Ninet, H Rousset, G Salles, C Broussolle, P Sève (2006) <i>Lupus</i> <i></i> <i></i> 15: 4 223-231<br/>

http://publicationslist.org/pascal.seve/refid33 2010-02-28T15:59:22Z

BACKGROUND: After exclusion of a masquerade syndrome, uveitis may be associated with infection, systemic diseases, specific ocular diseases, or may be drug-induced. In order to improve diagnostic strategy in uveitis, we performed a comparative study to assess the importance of internist and ophtalmologist's collaboration and we proposed a well-adapted diagnostic procedure. MATERIAL AND METHODS: A ...<br/><br/>J Le Scanff, P Sève, L Kodjikian, J-D Grange, C Broussolle (2006) <i>Rev Med Interne</i> <i></i> <i></i> 27: 9 671-678<br/>

http://publicationslist.org/pascal.seve/refid29 2010-02-28T15:59:22Z

BACKGROUND: The authors investigated how lymphopenia and low serum albumin levels correlate with the prognosis of patients with carcinoma of unknown primary (CUP). METHODS: Univariate and multivariate prognostic factor analyses were conducted in a population of 317 consecutive patients with CUP who were evaluated at the Cross Cancer Institute of Edmonton, Alberta, Canada, from 1998 to 2004. RESULT...<br/><br/>Pascal Seve, Isabelle Ray-Coquard, Veronique Trillet-Lenoir, Michael Sawyer, John Hanson, Christiane Broussolle, Sylvie Negrier, Charles Dumontet, John R Mackey (2006) <i>Cancer</i> <i></i> <i></i> 107: 11 2698-2705<br/>

http://publicationslist.org/pascal.seve/refid31 2010-02-28T15:59:22Z

This is a multicentric retrospective study of aspergillosis in patients treated by corticosteroids and/or immunosuppressive drugs for systemic diseases and a review of the literature. Nine patients, 5 men and 4 women, mean age of 62.8 years old were included among which Horton's diseases (3 cases), systemic lupus erythematosus (2), polymyositis (1), microscopic polyangiitis (1), idiopathic thrombo...<br/><br/>K Stankovic, P Sève, A Hot, N Magy, I Durieu, C Broussolle (2006) <i>Rev Med Interne</i> <i></i> <i></i> 27: 11 813-827<br/>

http://publicationslist.org/pascal.seve/refid36 2010-02-28T15:59:22Z

BACKGROUND: The authors investigated how comorbidities, age, and performance status were related to the choice of chemotherapy and to the prognosis of patients with carcinomas of unknown primary site (CUP). METHODS: Patients in Northern Alberta who were diagnosed with CUP during 2000 to 2003 were included (n = 389 patients). Survival was compared by age at diagnosis (ages <65 years, 65-74 years, a...<br/><br/>Pascal Seve, Michael Sawyer, John Hanson, Christiane Broussolle, Charles Dumontet, John R Mackey (2006) <i>Cancer</i> <i></i> <i></i> 106: 9 2058-2066<br/>

http://publicationslist.org/pascal.seve/refid38 2010-02-28T15:59:22Z

INTRODUCTION: Like Fusobacterium necrophorum, Fusobacterium nucleatum is capable causing Lemierre's syndrome. Various locations of venous thrombosis have been described associated with Fusobacterium sp. septicemia. EXEGESIS: We describe a 43-year old alcoholic patient with F.nucleatum septicemia complicated with hepatic abscesses, middle hepatic venous thrombosis, osteomyelitis and infiltrative pn...<br/><br/>K Le Roux, P Sève, E Gomard, A Boibieux, C Beziat, K Stankovic, C Broussolle (2006) <i>Rev Med Interne</i> <i></i> <i></i> 27: 6 482-486<br/>

http://publicationslist.org/pascal.seve/refid46 2010-02-28T15:59:22Z

P Sève, C Bui-Xuan, G David, K Stankovic, V Lapras, C Broussolle (2006) <i>Rev Med Interne</i> <i></i> <i></i> 27: 1 66-67<br/>

http://publicationslist.org/pascal.seve/refid39 2010-02-28T15:59:22Z

Monoclonal gammopathy has been reported rarely in association with infectious diseases. Viral infection has been the most frequently reported. We report a case of Bartonella quintana endocarditis in a 45-year-old homeless male associated with a monoclonal IgG kappa gammopathy. The gammopathy disappeared after 8 months of antibiotics while the Bartonella antibody titre was decreasing. This correlat...<br/><br/>Pascal Sève, Robert Turner, Katia Stankovic, Laurent Perard, Christiane Broussolle (2006) <i>Am J Hematol</i> <i></i> <i></i> 81: 2 115-117<br/>

http://publicationslist.org/pascal.seve/refid37 2010-02-28T15:59:22Z

PURPOSE: Carcinoma of unknown primary site is a common clinical syndrome, accounting for 2% of cancer patients. Diagnosis is a recurrent challenge for internists. Treatment is difficult and prognosis is still poor. This review presents one synthesis of diagnosis strategies and therapeutic trials. It envisages the interest of new molecular biology methods as well as therapeutic perspectives. CURREN...<br/><br/>P Sève, K Stankovic, A Charhon, C Broussolle (2006) <i>Rev Med Interne</i> <i></i> <i></i> 27: 7 532-545<br/>

http://publicationslist.org/pascal.seve/refid49 2010-02-28T15:59:22Z

The treatment of advanced non-small-cell lung cancer (NSCLC is based on the combination of platin and one of the following agents: taxanes, gemcitabine, vinorelbine or irinotecan. There are no significant differences in efficacy among these combinations suggesting that the maximum efficacy has been reached. In this review, we will consider the mechanisms of chemoresistance of the five groups of cy...<br/><br/>Pascal Sève, Charles Dumontet (2005) <i>Curr Med Chem Anticancer Agents</i> <i></i> <i></i> 5: 1 73-88<br/>

http://publicationslist.org/pascal.seve/refid48 2010-02-28T15:59:22Z

Pascal Sève, Olivier Dubreuil, Fadi Farhat, Henry Plauchu, Paul Touboul, Christiane Broussolle (2005) <i>J Thorac Cardiovasc Surg</i> <i></i> <i></i> 129: 3 680-681<br/>

http://publicationslist.org/pascal.seve/refid50 2010-02-28T15:59:22Z

PURPOSE: Autoimmune manifestations (AIM) are associated to common variable immunodeficiency (CVI) in about 20 to 25% of the cases. This study presents the clinical, biological characteristics and the evolution of nine patients developing CVI and AIM. A peripheral B-cell compartment analysis has been performed in seven cases. METHOD: This multicenter retrospective study analyses nine patients, six ...<br/><br/>M Pavic, P Sève, C Malcus, F Sarrot-Reynault, D Peyramond, P Debourdeau, D Andriamanantena, D Bouhour, N Philippe, H Rousset, C Broussolle (2005) <i>Rev Med Interne</i> <i></i> <i></i> 26: 2 95-102<br/>

http://publicationslist.org/pascal.seve/refid52 2010-02-28T15:59:22Z

We present the case of a 50-year-old female with polyarthralgias and dysphonia. Indirect laryngoscopy revealed the presence of cricoarytenoid arthritis. The patient complained of dryness of the eyes and oral mucosa and was diagnosed with Sjögren's syndrome. Treatment with prednisolone quickly brought remission of systemic and laryngeal symptoms as well as improvement in the results of video-laryn...<br/><br/>Pascal Sève, Marc Poupart, Cécile Bui-Xuan, Annick Charhon, Christiane Broussolle (2005) <i>Rheumatol Int</i> <i></i> <i></i> 25: 4 301-302<br/>

http://publicationslist.org/pascal.seve/refid53 2010-02-28T15:59:22Z

Survival is impaired in rheumatoid pericarditis complicated by cardiac compression by either tamponade or constriction. Conventional therapy with non-steroidal anti-inflammatory agents and glucocorticoids is frequently ineffective in reversing severe cardiac impairment and/or in preventing recurrences. Colchicine, an effective and safe treatment of idiopathic and post-viral pericarditis, has not b...<br/><br/>Pascal Sève, Katia Stankovic, Christiane Broussolle (2005) <i>Rheumatol Int</i> <i></i> <i></i> 25: 7 558-561<br/>

http://publicationslist.org/pascal.seve/refid58 2010-02-28T15:59:22Z

PURPOSE: To report on a patient affected by bilateral intermediate uveitis (IU) as the initial sign of an uveomeningitic syndrome. METHODS: Thorough history, physical examination and ancillary laboratory and radiological testing were performed in this observational case study. RESULTS: A 23-year-old Caucasian man developed bilateral IU, primarily diagnosed as "idiopathic" since a detailed etiologi...<br/><br/>Laurent Kodjikian, Pascal Seve, Phuc Le Hoang, Justus G Garweg (2005) <i>Graefes Arch Clin Exp Ophthalmol</i> <i></i> <i></i> 243: 3 263-265<br/>

http://publicationslist.org/pascal.seve/refid51 2010-02-28T15:59:22Z

OBJECTIVES: To describe 2 cases of parvovirus B19 (B19) infection mimicking systemic lupus erythematosus (SLE) and to identify all cases of SLE imitated by and/or associated with B19 in the medical literature. METHODS: A computer-assisted (PubMed) search of the medical literature from 1975 to 2003 was performed using the following key words: parvovirus, B19, SLE, lupus, antibodies, auto-immunity. ...<br/><br/>Pascal Sève, Tristan Ferry, Martial Koenig, Pascal Cathebras, Hugues Rousset, Christiane Broussolle (2005) <i>Semin Arthritis Rheum</i> <i></i> <i></i> 34: 4 642-648<br/>

http://publicationslist.org/pascal.seve/refid47 2010-02-28T15:59:22Z

Resistance to gemcitabine is likely to be multifactorial and could involve a number of mechanisms involved in drug penetration, metabolism and targeting. In vitro studies of resistant human cell lines have confirmed that human equilibrative nucleoside transporter 1 (hENT1)-deficient cells display resistance to gemcitabine. Overexpression of certain nucleotidases, such as cN-II, has also been frequ...<br/><br/>Pascal Sève, John R Mackey, Sylvie Isaac, Olivier Trédan, Pierre Jean Souquet, Maurice Pérol, Carol Cass, Charles Dumontet (2005) <i>Lung Cancer</i> <i></i> <i></i> 49: 3 363-370<br/>

http://publicationslist.org/pascal.seve/refid45 2010-02-28T15:59:22Z

OBJECTIVES: To describe 2 cases of adult Kawasaki Disease (KD) and to review the medical literature to better define the epidemiological, clinical, laboratory, histopathological, cardiovascular, and therapeutic aspects of adult KD compared with pediatric KD. METHODS: Report of 2 cases, and review of the literature using a Medline search from 1967 to June 2003. RESULTS: Including our 2 cases, there...<br/><br/>Pascal Sève, Katia Stankovic, Amar Smail, Denis Vital Durand, Guillaume Marchand, Christiane Broussolle (2005) <i>Semin Arthritis Rheum</i> <i></i> <i></i> 34: 6 785-792<br/>

http://publicationslist.org/pascal.seve/refid40 2010-02-28T15:59:22Z

Both fundamental and clinical studies suggest that class III beta-tubulin expression is associated with resistance to taxanes and constitutes a prognostic factor in several solid tumors. In this study, we assessed the prognostic and predictive value of class III beta-tubulin in tumors of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) treated with paclitaxel-based o...<br/><br/>Pascal Sève, John Mackey, Sylvie Isaac, Olivier Trédan, Pierre-Jean Souquet, Maurice Pérol, Raymond Lai, Alain Voloch, Charles Dumontet (2005) <i>Mol Cancer Ther</i> <i></i> <i></i> 4: 12 2001-2007<br/>

http://publicationslist.org/pascal.seve/refid42 2010-02-28T15:59:22Z

P Sève, K Stankovic, S Ronger, C Broussolle (2005) <i>Rev Med Interne</i> <i></i> <i></i> 26 Suppl 2: S240-S241<br/>

http://publicationslist.org/pascal.seve/refid41 2010-02-28T15:59:22Z

K Stankovic, P Sève, C Broussolle (2005) <i>Rev Med Interne</i> <i></i> <i></i> 26 Suppl 2: S277-S278<br/>

http://publicationslist.org/pascal.seve/refid43 2010-02-28T15:59:22Z

PURPOSE: To determine the prevalence and the prognostic value of microtubule component expression in tumors of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). EXPERIMENTAL DESIGN: Expression of microtubular components was immunohistochemically examined in 93 tumor samples from untreated patients with stage III and IV NSCLC. All patients received vinorelbine-based c...<br/><br/>Pascal Sève, Sylvie Isaac, Olivier Trédan, Pierre-Jean Souquet, Yves Pachéco, Maurice Pérol, Laurence Lafanéchère, Aurélie Penet, Eva-Laure Peiller, Charles Dumontet (2005) <i>Clin Cancer Res</i> <i></i> <i></i> 11: 15 5481-5486<br/>

http://publicationslist.org/pascal.seve/refid44 2010-02-28T15:59:22Z

Vasculitis associated with anti-neutrophil cytoplasmic antibodies has been reported in patients treated with anti-thyroid drugs and especially propylthiouracil. We report here a case of granulomatous eosinophilic vasculitis mimicking gastric neoplasm and peripheral eosinophilia in a 27-year-old man who was treated with carbimazole for 5 months for Graves' disease. Clinical and morphologic features...<br/><br/>P Sève, K Stankovic, V Michalet, T Vial, J-Y Scoazec, C Broussolle (2005) <i>J Intern Med</i> <i></i> <i></i> 258: 2 191-195<br/>

http://publicationslist.org/pascal.seve/refid59 2010-02-28T15:59:22Z

F Durupt, P Seve, C Roure, F Biron, D Raoult, C Broussolle (2004) <i>Eur J Clin Microbiol Infect Dis</i> <i></i> <i></i> 23: 10 790-791<br/>

http://publicationslist.org/pascal.seve/refid60 2010-02-28T15:59:22Z

M Pavic, P Sève, J Le Scanff, E Gomard, A Charhon, C Broussolle (2004) <i>Rev Med Interne</i> <i></i> <i></i> 25: 8 <br/>

http://publicationslist.org/pascal.seve/refid62 2010-02-28T15:59:22Z

P Sève, M Pavic, C Malcus, J Le Scanff, E Gomard, C Broussolle (2004) <i>Rev Med Interne</i> <i></i> <i></i> 25: 1 96-97<br/>

http://publicationslist.org/pascal.seve/refid61 2010-02-28T15:59:22Z

P Sève (2004) <i>Rev Med Interne</i> <i></i> <i></i> 25: 5 412-417<br/>

http://publicationslist.org/pascal.seve/refid54 2010-02-28T15:59:22Z

OBJECTIVES: The role of hepatitis C virus (HCV) infection in the pathogenesis of non-Hodgkin's lymphoma (NHL) is controversial. A high prevalence of HCV infection in patients with NHL has been reported in Italy and Japan. By contrast, several studies in Northern Europe and Canada have not found any increased prevalence of HCV in B-cell NHL, suggesting a possible geographic variation. We sought to ...<br/><br/>Pascal Sève, Philippe Renaudier, Annie J Sasco, Charles Dumontet, Gilles Salles, Bertrand Coiffier, Fabien Zoulim, Christiane Broussolle, Christian Trépo (2004) <i>Eur J Gastroenterol Hepatol</i> <i></i> <i></i> 16: 12 1361-1365<br/>

http://publicationslist.org/pascal.seve/refid57 2010-02-28T15:59:22Z

P Sève, T Ferry, T Vial, K Stankovic, C Bui-Xuan, C Broussolle (2004) <i>Rev Med Interne</i> <i></i> <i></i> 25 Suppl 2: S290-S291<br/>

http://publicationslist.org/pascal.seve/refid55 2010-02-28T15:59:22Z

Pascal Sève, Laurent Kodjikian, Cyrille Vautrin, Jean-Daniel Grange, Christiane Broussolle (2004) <i>Arch Ophthalmol</i> <i></i> <i></i> 122: 10 1548-1549<br/>

http://publicationslist.org/pascal.seve/refid56 2010-02-28T15:59:22Z

PURPOSE: Parvovirus B19 (B19) causes many clinical disorders, of which the most common are erythema infectiosum, aplastic crisis complicating chronic hemolytic anemia, and hydrops fetalis. In young adults, the skin eruption caused by B19 is accompanied by polyarthritis and polyarthralgia in 60% of the cases. Rheumatoid factors and other antibodies including antinuclear antibodies, anti-ADN, and an...<br/><br/>P Sève, T Ferry, A Charhon, A Calvet, C Broussolle (2004) <i>Rev Med Interne</i> <i></i> <i></i> 25: 10 740-751<br/>

http://publicationslist.org/pascal.seve/refid65 2010-02-28T15:59:22Z

PURPOSE: Review of the literature on adult Kawasaki disease. CURRENT KNOWLEDGE AND KEY POINTS: Kawasaki disease is an acute multisystemic vasculitis affecting predominantly young children. Several studies have suggested that Kawasaki disease is mediated by bacterial superantigens. The diagnosis is established on clinical criteria since no specific laboratory test yet exists for this disorder. The ...<br/><br/>P Sève, C Bui-Xuan, A Charhon, C Broussolle (2003) <i>Rev Med Interne</i> <i></i> <i></i> 24: 9 577-584<br/>

http://publicationslist.org/pascal.seve/refid66 2010-02-28T15:59:22Z

C Confavreux, P Sève, C Broussolle, P Renaudier, C Ducerf (2003) <i>QJM</i> <i></i> <i></i> 96: 4 317-318<br/>

http://publicationslist.org/pascal.seve/refid68 2010-02-28T15:59:22Z

P Seve, C Thieblemont, C Dumontet, F Bouafia, P Arnaud, O Hequet, D Espinouse, G Salles, B Coiffier, P Steve, B Coiffer (2001) <i>J Clin Oncol</i> <i></i> <i></i> 19: 7 2100-2101<br/>

http://publicationslist.org/pascal.seve/refid67 2010-02-28T15:59:22Z

INTRODUCTION: Pubic osteomyelitis has been described in three situations: children in whom Staphylococcus aureus is the preeminent pathogen; elderly patients who have undergone genitourinary procedures, and parenteral drug abusers. In contrast, pubic osteomyelitis in athletes has been described less often. We report three cases of acute staphylococcal pubic osteomyelitis in young athletic men and ...<br/><br/>P Sève, A Boibieux, C Pariset, P L Clouet, D Bouhour, S Tigaud, F Biron, C Chidiac, D Peyramond (2001) <i>Rev Med Interne</i> <i></i> <i></i> 22: 6 576-581<br/>

http://publicationslist.org/pascal.seve/refid72 2010-02-28T15:59:22Z

P Sève, A Boibieux, D Bouhour, M Gérard, C Neyret, D Peyramond (1998) <i>Presse Med</i> <i></i> <i></i> 27: 1 <br/>

http://publicationslist.org/pascal.seve/refid71 2010-02-28T15:59:22Z

INTRODUCTION: Necrobiotic xanthogranulomatosis is a rare cutaneous disorder usually associated with monoclonal gammopathy. Most frequently, cutaneous lesions involve the face (periorbital region) and the trunk, and are characterized by indurated xanthomatous plaques and nodules. EXEGESIS: We describe a patient presenting with necrobiotic xanthogranulomatosis that was unusual, as it was associated ...<br/><br/>P Sève, T Zénone, I Durieu, G Moulin, R Levrat (1998) <i>Rev Med Interne</i> <i></i> <i></i> 19: 5 338-340<br/>

http://publicationslist.org/pascal.seve/refid70 2010-02-28T15:59:22Z

P Sève, A Boibieux, F Biron, D Bouhour, A Rode, B Bancel, C Chidiac, D Peyramond (1998) <i>Ann Med Interne (Paris)</i> <i></i> <i></i> 149: 6 386-388<br/>

http://publicationslist.org/pascal.seve/refid69 2010-02-28T15:59:22Z

P Sève, P Felman, C Gouillat, A Charhon, C Broussolle (1998) <i>Rev Med Interne</i> <i></i> <i></i> 19: 11 839-841<br/>

http://publicationslist.org/pascal.seve/refid73 2010-02-28T15:59:22Z

T Zénone, P Sève, I Durieu, D Vital Durand (1997) <i>Presse Med</i> <i></i> <i></i> 26: 7 <br/>

http://publicationslist.org/pascal.seve/refid74 2010-02-28T15:59:22Z

We report the case of a 75-year old woman presenting sarcoid myopathy with pseudohypertrophy and skin involvement. Muscular biopsy confirmed the diagnosis of sarcoidosis. Symptomatic muscle involvement in sarcoidosis is rare. Three forms are described: myopathic, myositic and nodular. The relevance of imaging techniques is reviewed. Treatment is based on corticotherapy which is less efficient in m...<br/><br/>P Sève, T Zénone, I Durieu, D Pillon, D V Durand (1997) <i>Rev Med Interne</i> <i></i> <i></i> 18: 12 984-988<br/>