stefano corra's Publications List

Factors affecting injury severity among recreational skiers and snowboarders: an epidemiology study.

2010-05-13T12:42:38Z

Different results have been reported for skiing and snowboarding injuries worldwide. Few studies consider the injury severity score (ISS) for the evaluation of differences among injured skiers-snowboarders. The aim of this study is to identify possible risk factors that affect the severity of skiing and snowboarding injuries in three winter seasons (2002-2005) in South Tyrol. For every injured ski...

Paolo Girardi, Marco Braggion, Giuseppe Sacco, Franco De Giorgi, Stefano Corra (2010) Knee Surg Sports Traumatol Arthrosc :

Sledding injuries: is safety in this winter pastime overlooked? A three-year survey in South-Tyrol.

2010-05-13T12:42:38Z

ABSTRACT: BACKGROUND: Sledding is a popular traditional pastime in northern countries. However it is only rarely thought as a potentially dangerous activity even though serious injuries and deaths do occur. The purpose of this study was to calculate the incidence, the severity and the pattern of sledding-related injuries in our area, in order to set up possible preventive measures. RESULTS: In thr...

Stefano Corra, Franco De Giorgi (2007) J Trauma Manag Outcomes 1: 1

Skiing and snowboarding injuries and their impact on the emergency care system in South Tyrol: a restrospective analysis for the winter season 2001--2002.

2010-05-13T12:42:38Z

OBJECTIVES: To evaluate the incidence and the pattern of skiing and snowboarding injuries in South Tyrol and their impact on the emergency medical system in the winter season 2001--2002 in an attempt to rationalize and improve the emergency care and assist in prevention strategies. METHODS: All medical records of patients referred to our emergency department (ED) that sustained a skiing or snow-bo...

Stefano Corra, Alessandro Conci, Giorgio Conforti, Giuseppe Sacco, Franco De Giorgi (2004) Inj Control Saf Promot 11: 4 281-285

Three novel mutations of the PKD1 gene in Italian families with autosomal dominant polycystic kidney disease.

2010-05-13T12:42:38Z

A E Turco, S Rossetti, E Bresin, S Englisch, S Corrà, P F Pignatti (1997) Hum Mutat 10: 2 164-167

Autosomal dominant polycystic kidney disease (ADPKD) in an Italian family carrying a novel nonsense mutation and two missense changes in exons 44 and 45 of the PKD1 Gene.

2010-05-13T12:42:38Z

Sixty-seven Italian patients with autosomal dominant polycystic kidney disease (ADPKD) were screened for mutations in the 3' unique region of the PKD1 gene, using heteroduplex DNA analysis. Novel aberrant bands were detected in 3 patients from the same family. DNA sequencing showed a C to T transition in exon 44 (C12269T), resulting in a premature stop codon (R4020X), predicted to impair the synth...

S Rossetti, E Bresin, G Restagno, A Carbonara, S Corrà, O De Prisco, P F Pignatti, A E Turco (1996) Am J Med Genet 65: 2 155-159

A common polymorphism in exon 46 of the human autosomal dominant polycystic kidney disease 1 gene (PKD1).

2010-05-13T12:42:38Z

Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common single gene diseases in humans. We have identified a synonymous T to C transition polymorphism in exon 46 of the PKD1 gene (12838T-->C, Pro4209Pro). The polymorphism was present with similar frequencies in ADPKD patients and unaffected individuals. The heterozygosity, determined in 89 Italian individuals, was 0.347. The...

E Bresin, S Rossetti, S Englisch, S Corrà, P F Pignatti, A E Turco (1996) Mol Cell Probes 10: 6 463-465

Detection of two different nonsense mutations in exon 44 of the PKD1 gene in two unrelated Italian families with severe autosomal dominant polycystic kidney disease.

2010-05-13T12:42:38Z

Sixty-seven Italian patients with autosomal dominant polycystic kidney disease (ADPKD) were screened for mutations in the PKD1 gene. We used PCR, heteroduplex and single-strand conformation polymorphism DNA analysis, and automated DNA sequencing for exons 35, 36, 38, 44 and 45. We detected abnormal heteroduplexes in affected individuals from two unrelated families with clinically severe ADPKD phen...

A E Turco, S Rossetti, E Bresin, S Corrà, G Restagno, A Carbonara, O De Prisco, L Gammaro, G Maschio, P F Pignatti (1996) Nephrol Dial Transplant 11 Suppl 6: 10-12

Comparison of heteroduplex and single-strand conformation analyses, followed by ethidium fluorescence visualization, for the detection of mutations in four human genes.

2010-05-13T12:41:07Z

Non-isotopic DNA single-strand conformation analysis and heteroduplex analysis by ethidium bromide fluorescence visualization (SSCAE and HAE, respectively) were compared for the detection of 15 different naturally occurring mutations in 15 different DNA samples. The mutations included single nucleotide transitions, transversions and deletions, in CFTR (cystic fibrosis transmembrane conductance reg...

S Rossetti, S Corrà, M O Biasi, A E Turco, P F Pignatti (1995) Mol Cell Probes 9: 3 195-200

Erroneous genetic risk assessment of Alport syndrome.

2010-05-13T12:41:07Z

A E Turco, S Rossetti, E Bresin, S Corrá (1995) Lancet 346: 8984

A novel nonsense mutation in the PKD1 gene (C3817T) is associated with autosomal dominant polycystic kidney disease (ADPKD) in a large three-generation Italian family.

2010-05-13T12:41:07Z

We have looked for disease-causing mutations in the PKD1 gene in 20 unrelated ADPKD probands from northern Italy, all members of families in which our previous studies had indicated linkage to PKD1. Using PCR with primer pairs located in the 3' unique region of the gene and heteroduplex DNA analysis, we have detected novel aberrant bands in five affected individuals from the same family, which wer...

A E Turco, S Rossetti, E Bresin, S Corra, L Gammaro, G Maschio, P F Pignatti (1995) Hum Mol Genet 4: 8 1331-1335

Production of scatter factor-like activity by a nitrosamine-induced pancreatic cancer cell line.

2010-05-13T12:41:07Z

Two hamster pancreatic cancer cell lines, PC-1 and PC1.0, established from N-nitrosobis(2-oxopropyl)amine-induced pancreatic ductal/ductular adenocarcinomas exhibit different growth patterns. PC-1 cells, which produce well differentiated adenocarcinomas in vitro after allogeneic inoculation, form cell aggregates and characteristic island-like structures in vitro. PC1.0 cells, which produce poorly ...

M Hirota, H Egami, S Corra, H Fujii, W G Chaney, A Rizzino, P M Pour (1993) Carcinogenesis 14: 2 259-264

Modification of antigen expression in human and hamster pancreatic cancer cell lines induced by sodium butyrate.

2010-05-13T12:41:07Z

The effects of sodium butyrate (NaB) on the growth, morphology, and expression of blood group A, Lewis(a), and CA 19-9 antigen in the hamster pancreatic cancer cell lines, PC-1 (well differentiated) and PC-1.0 (poorly differentiated), and of blood group A, DU-PAN-2, and CA 19-9 antigens in four human pancreatic cancer cell lines, HPAF and CD11 (well differentiated) and CD18 and PANC-1 (poorly diff...

S Corra, K Kazakoff, M Mogaki, M Cano, P M Pour (1993) Teratog Carcinog Mutagen 13: 5 199-215

Submandibular gland as a site for islet transplantation.

2010-05-13T12:41:07Z

Homologous transplantation of islets of Langerhans into the submandibular glands of Syrian hamsters was successful in 8 out of 10 recipients. The technique was simple and led to formation of islets of various sizes within the parenchyma of the gland. The morphology and endocrine cell patterns of this islets were identical to pancreatic islets. The advantage of this model for islet transplantation ...

P M Pour, L G Weide, K Ueno, S Corra, K Kazakoff (1992) Int J Pancreatol 12: 2 187-191

Treatment of infected pancreatic necrosis without surgery. A reported case.

2010-05-13T12:41:07Z

C Bassi, S Corra, P Pederzoli (1992) Int J Pancreatol 11: 3 209-211

Cholecystokinin inhibits DNA alkylation induced by N-nitrosobis (2-oxopropyl)amine (BOP) in hamster pancreas.

2010-05-13T12:41:07Z

Cholecystokinin (CCK) inhibits pancreatic cancer but not hepatic tumor induction by N-nitrosobis (2-oxopropyl) amine (BOP) in hamsters when administered with or shortly before BOP. In this study, we evaluated the capability of sulfated CCK-8 to inhibit DNA alkylation in the hamster pancreas. We examined the pattern of O6-methylguanine (G6-Me) and N7-methylguanine (G7-Me) in pancreatic ductal, acin...

S Corra, K Kazakoff, T A Lawson, T E Adrian, P M Pour (1992) Cancer Lett 62: 3 251-256

Antibacterial and mezlocillin-enhancing activity of pure human pancreatic fluid.

2010-05-13T12:41:07Z

The majority of deaths in severe pancreatitis are the result of superinfection of necrotic tissue. The pathogen most commonly responsible for such infections is Escherichia coli. Antibiotic prophylaxis would appear a logical precaution. The antibacterial drugs of choice should possess two basic characteristics: they must be active against the flora responsible for the infections and must be capabl...

C Bassi, R Fontana, S Vesentini, G Cavallini, L Marchiori, M Falconi, S Corrà, P Pederzoli (1991) Int J Pancreatol 10: 3-4 293-297

Necrosectomy by lavage in the surgical treatment of severe necrotizing pancreatitis. Results in 263 patients.

2010-05-13T12:41:07Z

A conservative surgical technique for treatment of necrotizing pancreatitis is described. Standardized since 1976, the technique is based on washout mechanical necrosectomy accomplished by lavages via intraoperatively placed wide-bore drainage tubes. The overall mortality rate from necrotizing pancreatitis was thereby reduced from 61% (with resective technique) to 18%, and in 106 cases observed fr...

P Pederzoli, C Bassi, S Vesentini, C Iacono, N Nicoli, G Mangiante, S Corrà, M Falconi, F Nifosi, R Girelli (1990) Acta Chir Scand 156: 11-12 775-780