http://publicationslist.org/data/viviane.van.hoof/atom.xml Viviane Van Hoofhttp://publicationslist.org/viviane.van.hoof$basepathfavicon.icoRecent additions to Viviane Van Hoof's PublicationsList.org pagehttp://publicationslist.org/publications.png2009-04-29T14:32:24Z http://publicationslist.org/viviane.van.hoof/refid1 2009-04-29T14:29:21Z

BACKGROUND: Exercise increases natriuretic peptide levels in chronic heart failure (CHF) patients, but the effect is considered minor. We assessed acute and short-term release (<24 h) of NT-proBNP in CHF patients after a maximal cardiopulmonary exercise test (CPET) and 2 different submaximal training sessions. METHODS AND RESULTS: 102 CHF patients either performed CPET (Group 1), a 1 h endurance (...<br/><br/>Viviane M A Conraads, Cathérine De Maeyer, Paul Beckers, Nadine Possemiers, Manuella Martin, Viviane Van Hoof, Christiaan J Vrints (2008) <i>Eur J Heart Fail</i> <i></i> <i></i> 10: 8 793-795<br/>

http://publicationslist.org/viviane.van.hoof/refid6 2009-04-29T14:29:21Z

BACKGROUND: B-type natriuretic peptide (BNP) is used as prognostic marker in acute coronary syndromes. It is unknown whether BNP reflects the amount of jeopardised myocardium in the initial phase of acute ST-elevation myocardial infarction (STEMI). METHODS: Patients admitted for percutaneous coronary intervention in the acute phase of STEMI were studied. Samples for BNP were taken at the time of c...<br/><br/>Anne Vorlat, Marc J Claeys, Johan M Bosmans, Viviane Van Hoof, Christiaan J Vrints (2007) <i>Int J Cardiol</i> <i></i> <i></i> 114: 1 46-49<br/>

http://publicationslist.org/viviane.van.hoof/refid3 2009-04-29T14:29:21Z

The aim of this study was to test the influence of high-dose folic acid (10 mg/d) on endothelial function in patients referred for coronary intervention after an acute myocardial infarction (AMI) and determine its relation to homocysteine levels. Flow-mediated dilation (FMD) of the brachial artery was performed in 40 patients after AMI (16 with normal homocysteine levels and 24 patients with eleva...<br/><br/>An L Moens, Marc J Claeys, Floris L Wuyts, Inge Goovaerts, Els Van Hertbruggen, Luc C Wendelen, Viviane O Van Hoof, Christiaan J Vrints (2007) <i>Am J Cardiol</i> <i></i> <i></i> 99: 4 476-481<br/>

http://publicationslist.org/viviane.van.hoof/refid2 2009-04-29T14:29:21Z

The remnant kidney rat model has been extensively used for the evaluation of bone changes due to uremia. The present study aimed to assess the effect of the dietary phosphorus availability and of the severity of renal failure on bone histomorphometric changes and various biochemical markers over time in this model. Chronic renal failure (CRF) was induced in male Wistar rats by 5/6th nephrectomy. H...<br/><br/>Line Oste, Geert J Behets, Geert Dams, An R Bervoets, Rita L Marynissen, Hilde Geryl, Viviane O Van Hoof, Marc E De Broe, Patrick C D'Haese (2007) <i>Ren Fail</i> <i></i> <i></i> 29: 1 1-12<br/>

http://publicationslist.org/viviane.van.hoof/refid5 2009-04-29T14:29:21Z

The mouse mutant Ozzy, originating from an ENU-mutagenesis programme, displays a head bobbing phenotype. We report here that Ozzy mice show a clear deficit in vestibulo-ocular reflex (VOR). Micro-CT scanning of the inner ears showed narrowing and truncations of at least one of the semicircular canals and loss of the ampullae. Frequency-specific auditory-evoked brainstem response (ABR) tests reveal...<br/><br/>Karen Vrijens, Sofie Thys, Marcel T De Jeu, Andrei A Postnov, Markus Pfister, Luk Cox, An Zwijsen, Viviane Van Hoof, Marcus Mueller, Nora M De Clerck, Chris I De Zeeuw, Guy Van Camp, Lut Van Laer (2006) <i>Neurobiol Dis</i> <i></i> <i></i> 24: 1 28-40<br/>

http://publicationslist.org/viviane.van.hoof/refid4 2009-04-29T14:29:21Z

BACKGROUND: The Roche CARDIAC proBNP point-of-care (POC) test is the first test intended for the quantitative determination of N-terminal pro-brain natriuretic peptide (NT-proBNP) in whole blood as an aid in the diagnosis of suspected congestive heart failure, in the monitoring of patients with compensated left-ventricular dysfunction and in the risk stratification of patients with acute coronary ...<br/><br/>Christian Zugck, Manfred Nelles, Hugo A Katus, Paul O Collinson, David C Gaze, Bert Dikkeschei, Eberhard Gurr, Wiebke Hayen, Markus Haass, Christoph Hechler, Viviane van Hoof, Khadija Guerti, Carl van Waes, Gert Printzen, Kai Klopprogge, Ilse Schulz, Rainer Zerback (2006) <i>Clin Chem Lab Med</i> <i></i> <i></i> 44: 10 1269-1277<br/>

http://publicationslist.org/viviane.van.hoof/refid7 2009-04-29T14:29:21Z

Silicon (Si) deficiency in animals results in bone defects. Choline-stabilized orthosilicic acid (ch-OSA) was found to have a high bioavailability compared to other Si supplements. The effect of ch-OSA supplementation was investigated on bone loss in aged ovariectomized (OVX) rats. Female Wistar rats (n = 58, age 9 months) were randomized in three groups. One group was sham-operated (sham, n = 21)...<br/><br/>M Calomme, P Geusens, N Demeester, G J Behets, P D'Haese, J B Sindambiwe, V Van Hoof, D Vanden Berghe (2006) <i>Calcif Tissue Int</i> <i></i> <i></i> 78: 4 227-232<br/>

http://publicationslist.org/viviane.van.hoof/refid8 2009-04-29T14:29:21Z

BACKGROUND: Patients with impaired renal function can accumulate strontium in the bone, which has been associated with the development of osteomalacia. A causal role for strontium in the development of the disease was presented in chronic renal failure (CRF) rats. Strontium-ranelate has been put forward as a therapeutic agent in the treatment of osteoporosis. Since the target population for stront...<br/><br/>Line Oste, An R Bervoets, Geert J Behets, Geert Dams, Rita L Marijnissen, Hilde Geryl, Ludwig V Lamberts, Steven C Verberckmoes, Viviane O Van Hoof, Marc E De Broe, Patrick C D'Haese (2005) <i>Kidney Int</i> <i></i> <i></i> 67: 3 920-930<br/>

http://publicationslist.org/viviane.van.hoof/refid13 2009-04-29T14:30:10Z

This study was set up to determine the long-term (5 or more years) renal function after HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome during pregnancy and to answer the question whether long-term renal follow-up is necessary. Women with HELLP syndrome were compared with healthy control subjects who delivered their first child during the same period. There was no difference ...<br/><br/>Yves Jacquemyn, Lisbeth Jochems, Evelien Duiker, Jean-Louis Bosmans, Viviane Van Hoof, Christel Van Campenhout (2004) <i>Gynecol Obstet Invest</i> <i></i> <i></i> 57: 2 117-120<br/>

http://publicationslist.org/viviane.van.hoof/refid11 2009-04-29T14:30:10Z

OBJECTIVE: To report a case of D-lactic acid acidosis owing to massive oral ingestion of propylene glycol. CASE REPORT: A 72-year old man with known congestive failure was admitted to the ICU with encephalopathy. Twelve hours prior to admission he had erroneously ingested a large amount of propylene glycol (PG). The laboratory revealed high anion gap (anion gap = 27 meq/l) acidosis (arterial pH = ...<br/><br/>Philippe G Jorens, Hendrik E Demey, Paul J C Schepens, Vera Coucke, Gert A Verpooten, M M Couttenye, Viviane Van Hoof (2004) <i>J Toxicol Clin Toxicol</i> <i></i> <i></i> 42: 2 163-169<br/>

http://publicationslist.org/viviane.van.hoof/refid12 2009-04-29T14:30:10Z

OBJECTIVE: Parietal cell antibodies (PCAs) are found in 20% of type 1 diabetic patients, denoting autoimmune gastritis and pernicious anemia, which may predispose to enterochromaffin-like (ECL) cell hyper/dysplasia and gastric carcinoid tumors. We evaluated whether chromogranin A (CgA), 5-hydroxyindole acetic acid (5-HIAA), and neuron-specific enolase (NSE) contribute to screening for ECL cell hyp...<br/><br/>Christophe E M De Block, Gert Colpin, Kristof Thielemans, Willy Coopmans, Johannes J P M Bogers, Paul A Pelckmans, Eric A E Van Marck, Viviane Van Hoof, Manou Martin, Ivo H De Leeuw, Roger Bouillon, Luc F Van Gaal (2004) <i>Diabetes Care</i> <i></i> <i></i> 27: 6 1387-1393<br/>

http://publicationslist.org/viviane.van.hoof/refid10 2009-04-29T14:29:21Z

Growing complexity of diagnostic tests, combined with increased workload, stringent laboratory accreditation demands, continuous shortening of turn-around-time and budget restrictions have forced laboratories to automate most of their iterative tasks. Introduction of artificial intelligence by means of expert systems has gained an important place in this automation process. Different parts of clin...<br/><br/>Viviane Van Hoof, Arno Wormek, Sylvia Schleutermann, Theo Schumacher, Olivier Lothaire, Christian Trendelenburg (2004) <i>Stud Health Technol Inform</i> <i></i> <i></i> 107: Pt 1 89-93<br/>

http://publicationslist.org/viviane.van.hoof/refid9 2009-04-29T14:29:21Z

AIMS: This study was designed to evaluate the effects of combined endurance/resistance training on NT-proBNP levels in patients with chronic heart failure (CHF). The safety of resistive weight training for patients with CHF is questioned. Possible detrimental effects include an increase in ventricular diastolic pressure and secondary unfavourable remodelling. Circulating levels of the N-terminal f...<br/><br/>Viviane M Conraads, Paul Beckers, Johan Vaes, Manuella Martin, Viviane Van Hoof, Cathérine De Maeyer, Nadine Possemiers, Floris L Wuyts, Christiaan J Vrints (2004) <i>Eur Heart J</i> <i></i> <i></i> 25: 20 1797-1805<br/>

http://publicationslist.org/viviane.van.hoof/refid14 2009-04-29T14:30:10Z

BACKGROUND: Various biochemical markers have been evaluated in dialysis patients for the diagnosis of renal osteodystrophy (ROD). However, their value in predialysis patients with end-stage renal failure (ESRF) is not yet clear. METHODS: Bone histomorphometric evaluation was performed and biochemical markers of bone turnover were determined in serum of an unselected predialysis ESRF population (N ...<br/><br/>An R J Bervoets, Goce B Spasovski, Geert J Behets, Geert Dams, Momir H Polenakovic, Katica Zafirovska, Viviane O Van Hoof, Marc E De Broe, Patrick C D'Haese (2003) <i>Am J Kidney Dis</i> <i></i> <i></i> 41: 5 997-1007<br/>

http://publicationslist.org/viviane.van.hoof/refid16 2009-04-29T14:30:10Z

BACKGROUND: Fifteen to 20% of type 1 diabetic patients exhibit parietal cell antibodies (PCA), which are associated with autoimmune gastritis, hypochlorhydria, iron deficiency and pernicious anaemia. AIM: To examine whether Helicobacter pylori infection could explain the high prevalence of PCA and autoimmune gastropathy in diabetes. If so, H. pylori eradication could prevent autoimmune gastritis. ...<br/><br/>C E M De Block, I H De Leeuw, J J P M Bogers, P A Pelckmans, M M Ieven, E A E Van Marck, V Van Hoof, E Máday, K L Van Acker, L F Van Gaal (2002) <i>Aliment Pharmacol Ther</i> <i></i> <i></i> 16: 2 281-289<br/>

http://publicationslist.org/viviane.van.hoof/refid15 2009-04-29T14:30:10Z

Familial amyloidotic polyneuropathy is a systemic amyloidosis with a dismal prognosis for which a surgical treatment exists. Awareness of the clinical characteristics of the disease is critical for early genetic diagnosis and timely referral for liver transplantation. In this report we describe the history of a 49-year-old man in whom non-AA amyloidotic infiltration of the heart and the intestinal...<br/><br/>Viviane M Conraads, Cecile G Colpaert, Viviane Van Hoof, Ole B Suhr, Christiaan J Vrints (2002) <i>J Heart Lung Transplant</i> <i></i> <i></i> 21: 8 932-934<br/>

http://publicationslist.org/viviane.van.hoof/refid17 2009-04-29T14:30:10Z

A J Deprettere, A Eykens, V Van Hoof (2001) <i>J Pediatr Gastroenterol Nutr</i> <i></i> <i></i> 33: 3 346-348<br/>

http://publicationslist.org/viviane.van.hoof/refid18 2009-04-29T14:30:10Z

OBJECTIVE: A total of 15-20% of type 1 diabetic patients have parietal cell antibodies (PCAs). PCA+ subjects are at increased risk for iron deficiency anemia and atrophic gastritis. Recently, soluble transferrin receptor (sTfR) levels have proven to be a sensitive indicator for iron deficiency They are, in contrast with ferritin levels, independent of inflammation, liver and hormonal status, and s...<br/><br/>C E De Block, C M Van Campenhout, I H De Leeuw, B M Keenoy, M Martin, V Van Hoof, L F Van Gaal (2000) <i>Diabetes Care</i> <i></i> <i></i> 23: 9 1384-1388<br/>

http://publicationslist.org/viviane.van.hoof/refid19 2009-04-29T14:30:10Z

We report on three families with the Gly341Arg ryanodine receptor gene (RYR1) mutation. Thirteen individuals were heterozygote carriers of the Gly341Arg mutation and had clearly positive in vitro contracture tests, indicating malignant hyperthermia susceptibility. Nine Gly341Arg mutation positive individuals from two families had elevated serum creatine kinase (CK) activity at rest (up to six time...<br/><br/>K G Monsieurs, C Van Broeckhoven, J J Martin, V O Van Hoof, L Heytens (1998) <i>J Neurol Sci</i> <i></i> <i></i> 154: 1 62-65<br/>

http://publicationslist.org/viviane.van.hoof/refid21 2009-04-29T14:30:49Z

BACKGROUND: Adynamic bone disease (ABD) has been described in the current dialysis population to have an unexpectedly high prevalence. Moreover, it is clearly more prevalent in CAPD patients, compared to haemodialysis patients. Recently we demonstrated that both a low (< or = 27 U/1) level of bone alkaline phosphatase (BAP) as determined by an optimized agarose gel electrophoretic technique and a ...<br/><br/>M M Couttenye, P C D'Haese, J T Deng, V O Van Hoof, G A Verpooten, M E De Broe (1997) <i>Nephrol Dial Transplant</i> <i></i> <i></i> 12: 10 2144-2150<br/>

http://publicationslist.org/viviane.van.hoof/refid22 2009-04-29T14:30:49Z

An immunoradiometric assay (IRMA), involving specific monoclonal antibodies (Ostase, Hybritech) and agarose electrophoresis (Isopal, Beckman), two methods for quantification of serum bone alkaline phosphatase (ALP), a marker for osteoblastic activity, were analytically and clinically compared in 293 patients: 79 with end-stage renal failure treated with hemodialysis and 214 with malignant disease....<br/><br/>M Martin, V Van Hoof, M Couttenye, A Prove, P Blockx (1997) <i>Anticancer Res</i> <i></i> <i></i> 17: 4B 3167-3170<br/>

http://publicationslist.org/viviane.van.hoof/refid20 2009-04-29T14:30:49Z

Diagnostic enzymology measures the serum or plasma levels of enzymes that were originally located within the cell, or were attached to its plasma membrane with their active sites exposed to the external milieu. The process by which they are released varies under different physiological and pathological conditions. In this way, shedding of hepatocyte plasma membranes is thought to be responsible fo...<br/><br/>V O Van Hoof, J T Deng, M E De Broe (1997) <i>Clin Chim Acta</i> <i></i> <i></i> 266: 1 23-31<br/>

http://publicationslist.org/viviane.van.hoof/refid25 2009-04-29T14:30:49Z

Membrane-bound liver alkaline phosphatase (Mem-LiALP, EC 3.1.3.1) is a high-molecular-mass liver alkaline phosphatase (ALP) present in metastatic, infiltrative and cholestatic liver disease. Shedding of hepatocyte plasma membrane fragments (LiPMF) is thought to be responsible for the appearance of Mem-LiALP in the circulation. Several other membrane-bound enzymes, such as gamma-glutamyltransferase...<br/><br/>J T Deng, M F Hoylaerts, E J Nouwen, M E De Broe, V O Van Hoof (1996) <i>Hepatology</i> <i></i> <i></i> 23: 3 445-454<br/>

http://publicationslist.org/viviane.van.hoof/refid24 2009-04-29T14:30:49Z

BACKGROUND. Adynamic bone disease was recently described to be increasingly prevalent in the dialysis population. At present the diagnosis of this type of renal osteodystrophy can only be made by bone histomorphometry. We assessed the value of different biochemical serum markers in the diagnosis of adynamic bone disease. METHODS. In 103 haemodialysis patients a bone biopsy was performed after doub...<br/><br/>M M Couttenye, P C D'Haese, V O Van Hoof, E Lemoniatou, W Goodman, G A Verpooten, M E De Broe (1996) <i>Nephrol Dial Transplant</i> <i></i> <i></i> 11: 6 1065-1072<br/>

http://publicationslist.org/viviane.van.hoof/refid23 2009-04-29T14:30:49Z

Circulating liver plasma membrane fragments (LPMF) were purified from human serum by means of a monoclonal antileucine aminopeptidase antibody, AD-1. This was done by immunoaffinity chromatography or by incubating the sera with AD-1-coated nitrocellulose disks. Alkaline phosphatase (ALP, EC 3.1.3.1) is bound to these LPMF through a glycosylphosphatidylinositol (GPI) anchor and is referred to as me...<br/><br/>J T Deng, M F Hoylaerts, M E De Broe, V O van Hoof (1996) <i>Am J Physiol</i> <i></i> <i></i> 271: 4 Pt 1 G655-G663<br/>

http://publicationslist.org/viviane.van.hoof/refid26 2009-04-29T14:30:49Z

Agarose electrophoresis (Isopal, Beckman) and an immunoradiometric assay (IRMA) involving specific monoclonal antibodies (Ostase, Hybritech), two methods for the quantification of serum bone alkaline phosphatase (ALP, EC 3.1.3.1), a marker of osteoblastic activity, were compared in 293 patients: 79 with end-stage renal failure treated with hemodialysis and 214 with malignant disease. Overall corre...<br/><br/>V O Van Hoof, M Martin, P Blockx, A Prove, A Van Oosterom, M M Couttenye, M E De Broe, L G Lepoutre (1995) <i>Clin Chem</i> <i></i> <i></i> 41: 6 Pt 1 853-857<br/>

http://publicationslist.org/viviane.van.hoof/refid27 2009-04-29T14:30:49Z

Alkaline phosphatase (ALP, EC 3.1.3.1) is a membrane-bound metalloenzyme that consists of a group of true isoenzymes, all glycoproteins, encoded for by at least four different gene loci: tissue-nonspecific, intestinal, placental, and germ-cell ALP. Through posttranslational modifications of the tissue-nonspecific gene, for example, through differences in carbohydrate composition, bone and liver AL...<br/><br/>V O Van Hoof, M E De Broe (1994) <i>Crit Rev Clin Lab Sci</i> <i></i> <i></i> 31: 3 197-293<br/>

http://publicationslist.org/viviane.van.hoof/refid29 2009-04-29T14:30:49Z

Human intestinal alkaline phosphatase (IAP) can be released by the enterocyte into duodenal fluid as a mixture of three isoforms. A proportion of the enzyme is associated with triple-layered membrane vesicles (vesicular IAP). Although, occasionally, free hydrophilic IAP dimers are present, the remaining enzyme usually consists of a mixture of hydrophobic IAP dimers and more complex hydrophobic IAP...<br/><br/>J T Deng, M F Hoylaerts, V O Van Hoof, M E De Broe (1992) <i>Clin Chem</i> <i></i> <i></i> 38: 12 2532-2538<br/>

http://publicationslist.org/viviane.van.hoof/refid28 2009-04-29T14:30:49Z

Early treatment of patients with malignant disease and liver or bone metastasis may increase their survival time. We have used the activity patterns of liver and bone isoenzymes of alkaline phosphatase (ALP), separated by agarose gel electrophoresis, to detect early metastasis. We studied ALP isoenzyme patterns in a background population of 101 patients with no evidence of any disease that might i...<br/><br/>V O Van Hoof, A T Van Oosterom, L G Lepoutre, M E De Broe (1992) <i>Clin Chem</i> <i></i> <i></i> 38: 12 2546-2551<br/>

http://publicationslist.org/viviane.van.hoof/refid32 2009-04-29T14:31:19Z

V O Van Hoof, M F Hoylaerts, M Van Mullen, L G Lepoutre, M E De Broe (1991) <i>Clin Chem</i> <i></i> <i></i> 37: 2 304-305<br/>

http://publicationslist.org/viviane.van.hoof/refid31 2009-04-29T14:31:19Z

The diagnostic value of serum amylase determination for pancreatic disease has been questioned due to its lack of specificity. Several methods have been developed to separate the tissue-unspecific salivary fractions from the tissue-specific pancreatic fractions. Agarose or cellulose acetate gel electrophoresis are most suitable for clinical practice. The isoamylase patterns were studied by agarose...<br/><br/>P Michielsen, V Van Hoof, L Lepoutre, Y Van Maercke (1991) <i>Acta Gastroenterol Belg</i> <i></i> <i></i> 54: 2 164-168<br/>

http://publicationslist.org/viviane.van.hoof/refid30 2009-04-29T14:31:19Z

M E De Broe, V O Van Hoof (1991) <i>Clin Chem</i> <i></i> <i></i> 37: 6 783-784<br/>

http://publicationslist.org/viviane.van.hoof/refid35 2009-04-29T14:31:19Z

V Van Hoof, L Geeraerts, H Van Meirvenne, M Van Mullem, R Chevigné, C Van Campenhout, L Lepoutre (1990) <i>Clin Chem</i> <i></i> <i></i> 36: 6 1251-1252<br/>

http://publicationslist.org/viviane.van.hoof/refid34 2009-04-29T14:31:19Z

We separated isoenzymes of alkaline phosphatase (ALP; EC 3.1.3.1) in 1383 sera of normal individuals (ages 4-65 years) by agarose electrophoresis with the Isopal system (Analis). As expected, the predominant isoenzyme in children was of bone origin, and almost all (99%) of the children had low activities of a second bone fraction, "bone variant" ALP. The "bone variant" disappeared after age 17 in ...<br/><br/>V O Van Hoof, M F Hoylaerts, H Geryl, M Van Mullem, L G Lepoutre, M E De Broe (1990) <i>Clin Chem</i> <i></i> <i></i> 36: 6 875-878<br/>

http://publicationslist.org/viviane.van.hoof/refid33 2009-04-29T14:31:19Z

V O Van Hoof, C M Van Campenhout, M E De Broe, L G Lepoutre (1990) <i>Clin Chem</i> <i></i> <i></i> 36: 11 2012-2014<br/>

http://publicationslist.org/viviane.van.hoof/refid36 2009-04-29T14:31:19Z

Human long-term bone marrow cultures (HLTBMCs) were established with bone marrow (BM) collected from five patients with myelomatous disorders (four with multiple myeloma, one with plasma cell leukemia). In all cases, up to at least 6 weeks of culture, there was a persistence of the monoclonal plasma cell population in the adherent layer of the culture. In some cultures proliferating plasma cells c...<br/><br/>Z N Berneman, Z Z Chen, M Ramael, V Van Hoof, M E Peetermans (1989) <i>Leukemia</i> <i></i> <i></i> 3: 2 151-154<br/>

http://publicationslist.org/viviane.van.hoof/refid37 2009-04-29T14:31:19Z

A modified agarose electrophoretic system for the separation of alkaline phosphatase (ALP, EC 3.1.3.1) isoenzymes is described. Bone, liver, high-molecular-mass, and intestinal ALP are separated with high reproducibility. The sensitivity of the agarose system is superior to cellulose acetate in detecting high-Mr ALP. Correlation is good between bone ALP fractions scanned before and after treatment...<br/><br/>V O Van Hoof, L G Lepoutre, M F Hoylaerts, R Chevigné, M E De Broe (1988) <i>Clin Chem</i> <i></i> <i></i> 34: 9 1857-1862<br/>