Division of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, Shuang Ho Hospital, Taipei Medical University, Taipei 23561, Taiwan
 | sbfang@tmu.edu.tw |
Dr Shiuh-Bin Fang is the incumbent Director of Division of Pediatric Gastroenterology and Hepatology, Department of Pediatrics at Taipei Medical University Shuang Ho Hospital. He is also Assistant Professor of Pediatrics at Taipei Medical University. He received his MD degree with the Best Intern Award at Taipei Medical University in 1993. After serving as a medical officer in the army for 2 years, he did his pediatric residency from 1995 to 1998 in Mackay Memorial Hospital. He was awarded as the Best Resident to continue his fellowship in paediatric gastroenterology and hepatology from 1998 to 2000. Afterward he worked as an Attending Physician in Pediatrics in Chung Shan Medical University Hospital in Taichung and Taiwan Adventist Hospital in Taipei. During the period between 2001 and 2007, he dedicated himself to not only clinical practice but also teaching medical and nursing students. Meanwhile, he collaborated with Professors Jung-Tang Huang and Shao-Yi Hou at National Taipei University of Technology to develop rapid non-PCR methods for early detection of Salmonella spp. and its antibiotic resistance using nanotechnology. This project supported by a grant from National Health Research Institutes in Taiwan. He was promoted as Director of the Department of Pediatrics in Taiwan Adventist Hospital from 2005 to 2006.
Awarded with the Taiwan Government Scholarship, Dr Fang earned his PhD under the supervision of Professor Alan Phillips in University College London Medical School in 2011, focusing on the early interactions of non-typhoidal Salmonella with human intestinal epithelium. During his study, he frequently collaborated with Professor Duncan Maskell in University of Cambridge and Wellcome Trust Sanger Institute and identified 6 novel Salmonella virulence genes responsible for bacterial adhesion, invasion, and intracellular replication in human epithelial cells. He returned Taiwan to continue his clinical and academic career at Taipei Medical University in June 2011 and successfully got three national grants from National Health Research Institutes and National Science Council during 2012-2014. His current research involves study of Salmonella virulence genes, attenuated Salmonella strains as oral vaccine vectors, regulation of non-typhoidal Salmonella on host innate immunity (particularly human β-defensin 3), effects/mechanisms of probiotics/health foods, and pathogen-host interactions using human intestinal in vitro organ culture and in vitro M cell models, showing his great interest in translational medicine bridging basic and clinical science.
Awarded with the Taiwan Government Scholarship, Dr Fang earned his PhD under the supervision of Professor Alan Phillips in University College London Medical School in 2011, focusing on the early interactions of non-typhoidal Salmonella with human intestinal epithelium. During his study, he frequently collaborated with Professor Duncan Maskell in University of Cambridge and Wellcome Trust Sanger Institute and identified 6 novel Salmonella virulence genes responsible for bacterial adhesion, invasion, and intracellular replication in human epithelial cells. He returned Taiwan to continue his clinical and academic career at Taipei Medical University in June 2011 and successfully got three national grants from National Health Research Institutes and National Science Council during 2012-2014. His current research involves study of Salmonella virulence genes, attenuated Salmonella strains as oral vaccine vectors, regulation of non-typhoidal Salmonella on host innate immunity (particularly human β-defensin 3), effects/mechanisms of probiotics/health foods, and pathogen-host interactions using human intestinal in vitro organ culture and in vitro M cell models, showing his great interest in translational medicine bridging basic and clinical science.
