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Jacques Griffet


jgriffet@chu-grenoble.fr

Journal articles

2013
J Leroux, P - H Vivier, M Ould Slimane, E Foulongne, S Abu-Amara, J Lechevallier, J Griffet (2013)  Early diagnosis of thoracolumbar spine fractures in children. A prospective study.   Orthop Traumatol Surg Res 99: 1. 60-65 Feb  
Abstract: Early detection of spine fractures in children is difficult because the clinical examination does not always raise worrisome symptoms and the vertebrae are still cartilaginous, and consequently incompletely visualized on routine X-rays. Therefore, diagnosis is often delayed or missed.
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2012
Sébastien Ruatti, Aurélien Courvoisier, Ahmad Eid, Jacques Griffet (2012)  Ureteral injury after percutaneous iliosacral fixation: a case report and literature review.   J Pediatr Surg 47: 8. e13-e16 Aug  
Abstract: We report a case of right ureter injury in an 11-year-old girl after a percutaneous iliosacral screwing with non-computer-assisted fluoroscopic guidance. The indication was a pelvic ring fracture, C1-1 in the Tile modified AO classification (J Am Acad Orthop Surg. 1996;4:143-151). The mechanism was a ski accident. A percutaneous iliosacral screwing was performed to stabilize the right iliac wing fracture. Twelve days after the initial trauma, a right ureter tear was highlighted, just opposite the fourth lumbar vertebra. Uneventful spontaneous healing of the ureteral injury site occurred following double J-stent catheterization.
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2011
Jacques Griffet, Julien Leroux, Toni El Hayek (2011)  Lumbopelvic stabilization with external fixator in a patient with lumbosacral agenesis.   Eur Spine J 20 Suppl 2: S161-S165 Jul  
Abstract: A case of caudal regression syndrome in which rehabilitation was obtained by lumbopelvic distraction and stabilization with external fixation Orthofix(®) is presented. The objective of the study is to describe the benefit of spine external fixator in caudal regression syndrome. Caudal regression syndrome is a rare and sporadic neural defect of distal spinal segments affecting the development of the spinal cord. It is characterized by vertebropelvic instability and essentially manifests as neurological deficit in the lower limbs and absence of bladder and bowel control. Pluridisciplinary management of this affection is complex. The clinical presentation and treatment of caudal regression syndromes are reviewed. A case of a boy for whom physical rehabilitation was obtained with external fixation Orthofix(®) is presented. Lumbopelvic stabilization was performed with autograft and allograft bone. A spine distraction was performed with external fixation with pedicular screws in L1 and L2 and in the pelvis bone. An elongation of 19 mm was obtained in 35 days. The external fixator was removed after 4 months and a spine cast was applied during 8 months. This treatment resulted in lumbopelvic nonunion of very low mobility. Lumbopelvic stability and the disappearance of pain were achieved. Sitting position was stable without hand support. At 14 years of follow-up, his condition is stable with possible deambulation at home with crutches. Lumbopelvic arthrodesis in caudal regression syndrome is difficult to obtain. The use of spine external fixator, however, allows trunk elongation and can achieve a stable sitting and upright position.
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R Recours, G Hanula, M Travert, C Sabiston, J Griffet (2011)  Governmental interventions and youth physical activity in France.   Child Care Health Dev 37: 3. 309-312 May  
Abstract: Data from a representative sample of 2474 French youth show that, despite a 7-year French Ministry of Health strategy for nutrition and physical activities, adolescents' motivation to practise sports and physical activities decreased significantly between 2001 and 2008. While this paper focuses on the context of physical activity in France, the general discussion may be applicable to other countries concerned with the obesity pandemic.
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Jacques Griffet, Ioana Oborocianu, Amandine Rubio, Julien Leroux, Jerome Lauron, Toni Hayek (2011)  Percutaneous aspiration irrigation drainage technique in the management of septic arthritis in children.   J Trauma 70: 2. 377-383 Feb  
Abstract: Septic arthritis in childhood is a therapeutic emergency. The authors present their experience using an intermediate technique with the advantages of the percutaneous aspiration irrigation drainage: joint aspiration, irrigation, and declivious drainage.
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Jacques Griffet, Julien Leroux, Nouar Boudjouraf, Ahmad Abou-Daher, Toni El Hayek (2011)  Elastic stable intramedullary nailing of tibial shaft fractures in children.   J Child Orthop 5: 4. 297-304 Aug  
Abstract: Tibial fractures in the skeletally immature patient are usually treated without surgery. Elastic stable intramedullary nailing (ESIN) is commonly used for other diaphyseal fracture locations. Its advantages are minimally invasive surgery with a short hospitalisation duration, primary bone union and early weight bearing. The purpose of this study was to assess the use of ESIN in displaced tibial fractures in children over 6 years old and in cases of polytrauma.
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J Griffet, L Decrocq, H Rauscent, C Richelme, M Fournier (2011)  Lower extremity surgery in muscular dystrophy.   Orthop Traumatol Surg Res 97: 6. 634-638 Oct  
Abstract: The natural progression of neuromuscular diseases results in inevitable musculotendinous contractures, most often in spite of early treatment. Surgery corrects this. The aim of this study was to evaluate the results of tendon surgery in these cases.
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2009
Amandine S Rubio, Jacques R Griffet, Hervé Caci, Etienne Bérard, Toni El Hayek, Patrick Boutté (2009)  The moulded baby syndrome: incidence and risk factors regarding 1,001 neonates.   Eur J Pediatr 168: 5. 605-611 May  
Abstract: Postural deformities are frequent in neonates. The moulded baby syndrome (MBS) comprises one or more of the following disorders: plagiocephaly, torticollis, congenital scoliosis, pelvic obliquity, adduction contracture of a hip and/or malpositions of the knees or feet. We analysed the incidence of MBS in healthy neonates and identified the risk factors of its composing elements. One thousand and one healthy neonates were examined on the second or third day of life by the same paediatrician. Familial, obstetrical, perinatal history and putative risk factors for postural deformities were collected. Families of newborns with a torticollis or plagiocephaly were given positioning advice and the outcome was evaluated by a phone survey 2 months later. MBS was detected in 107 neonates (10.7%): 97 plagiocephalies or torticollis, 25 congenital scoliosis or pelvic obliquities, and 13 malpositions of the knees or feet. We identified risk factors related to the mother (age: OR=1.39, parity: OR=0.643), to the obstetrical history (preterm labour: OR=1.65, oligoamnios: OR=10.179, breech presentation: OR=2.746, pregnancy toxaemia: OR=3.773, instrumental delivery: OR=6.028) and to the newborn (male gender: OR=1.982, birth length: OR=1.196). The initial plagiocephaly or torticollis improved in 77% of infants after 2 months of stimulation and positioning measures. Paediatricians should be alert regarding the frequent but subtle MBS postural deformities and give positioning advice to the parents. A neonate of male gender or greater birth length, with an older primiparous mother, a history of preterm labour, oligoamnios or pregnancy toxaemia, a breech presentation or an assisted delivery is more likely to have MBS.
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Charlotte Lernout, Hervé Haas, Amandine Rubio, Jacques Griffet (2009)  Pediatric intervertebral disk calcification in childhood: three case reports and review of literature.   Childs Nerv Syst 25: 8. 1019-1023 Aug  
Abstract: Intervertebral disk calcification is a rare childhood disease. The etiology of disk calcification in children remains unclear.
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Toni el Hayek, Thomas D'Ollone, Amandine Rubio, Simon Lusakisimo, Jacques Griffet (2009)  A too-long anterior process of the calcaneus: a report of 31 operated cases.   J Pediatr Orthop B 18: 4. 163-166 Jul  
Abstract: A too-long anterior process of the calcaneus is one of the causes of repeated sprained ankles or painful feet in the child or adolescent that is often ignored and misdiagnosed. Among 31 cases of adolescents having consulted for these symptoms, a too-long anterior process of the calcaneus was discovered on radiographs, and explored in detail with a computed tomography scan or an MRI. The decision for surgical resection was taken considering the discomfort expressed by these children. The intraoperative observation corroborated the radiological findings and permitted a better understanding of the mechanisms responsible for the pain, the repeated sprained ankles and other instabilities. The surgical resection, which is a simple procedure, gave very good results. One must nevertheless be aware of the possible secondary lesions because of repeated sprained ankles: breakage of the lateral ligaments of the ankle and external malleolus nonunion or talus osteochondritis, which can compromise the operation's result, if they are not treated simultaneously.
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Jean Breaud, Amandine Rubio, Julien Leroux, Jacques Griffet (2009)  Residual hip growth after pinning of slipped capital femoral epiphysis.   J Pediatr Orthop B 18: 1. 7-9 Jan  
Abstract: Screwing of slipped capital femoral epiphysis must prevent its further slipping by prematurely fusing the physis. Whichever material is used, persistent femoral growth has been described, thereby increasing the risk of bone deformation. The objective of this study is to evaluate the residual growth after screwing of slipped capital femoral epiphysis. This study concerned 26 children, among which 13 children have been included, and 13 children excluded because of an incomplete clinical or radiological follow-up, or treatment by another technique. The pathological hip was treated with one screw (in eight cases) or two screws (in five cases). The controlateral hip was fixed with one screw. The different measures were taken on anteroposterior radiographs done the days after surgery, and on the first radiograph on which the growth plate had fused. Growth plate fusion was obtained after an average of 20 months. Each patient had presented a residual growth of at least one hip, thus 85% of the 26 fixed screws. Among the four hips, which did not grow, three were pathological, and were fixed by one screw (in one case) or two screws (in two cases), in a central or medial position. There was not any statistical relationship between the growth persistence and the other studied criteria. These results, proving the growth persistency, suggest that the follow-up must be extremely careful, as the number of threads crossing the growth plate will decrease, with the risk of loss of mechanical stability and reappearance of the femoral epiphysis slippage.
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d'Ollonne Thomas, Amandine Rubio, Julien Leroux, Simon Lusakisimo, Toni Hayek, Jacques Griffet (2009)  Early reduction versus skin traction in the orthopaedic treatment of femoral shaft fractures in children under 6 years old.   J Child Orthop 3: 3. 209-215 Jun  
Abstract: Femoral shaft fractures occur very frequently in children, and their prognosis usually is good. Nonoperative treatment is the gold standard for children under 6 years because of the excellent bony union and the remodelling qualities.
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Sophie Pierron, Christian Richelme, Valérie Triolo, Jean Christophe Mas, Jacques Griffet, Houda Karmous-Benailly, M Quere, Tadashi Kaname, Jean-Claude Lambert, Fabienne Giuliano (2009)  Evolution of a patient with Bohring-Opitz syndrome.   Am J Med Genet A 149A: 8. 1754-1757 Aug  
Abstract: We detailed the story from birth to the age of 5 years 9 months, of the oldest patient reported with a Bohring-Opitz syndrome with the three main diagnostic criteria: characteristic facial appearance, fixed contractures of the upper limbs and severe feeding difficulties. The facial anomalies described in our patient were microcephaly, bitemporal narrowing, "puffy" cheeks, forehead naevus flammeus, hypoplastic orbital ridges, prominent eyes, broad nasal bridge, high arched palate, buccal-alveola frenula and retrognathism. The magnetic resonance imaging (MRI) of the brain showed a hypoplastic corpus callosum and a narrowed upper cervical canal; and the cervical MRI showed a malformation of the atlas consisting in an agenesis of the anterior arch and an anterior slip of the posterior arch. We focused on her neurological and nutritional evolution. Despite the gastrostomy and a Nissen fundoplication at age 7 months, she still had developmental growth delays overall (<3rd centile). At 3 years 9 months of age, she began to put on weight quickly, which seemed to be atypical. Meanwhile she developed epilepsy, which was controlled with specific drugs. Currently, she is 5 years 9 months old and has significant psychomotor retardation, although this disease is often fatal in early childhood, due to obstructive apnea and unexplained bradycardia.
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2007
Cécile Martha, Jean Griffet (2007)  Brief report: how do adolescents perceive the risks related to cell-phone use?   J Adolesc 30: 3. 513-521 Jun  
Abstract: Besides the social risks of incivility and impoliteness (I-incivility), cell-phone use is classically associated with two types of physical risk: microwave radiation (LIMRadiation) and decreased attention while driving (CPUWDriving). As the literature has showed that adolescents' risky behavior was consistent with their risk perception, we ran a self-report survey to evaluate 1/how French adolescents (n=1129) perceived physical risks related to CPUWDriving, exposure to LIMRadiation, and social risks related to I-incivility; and 2/the factors underlying these risk perceptions. Results showed that adolescents have an acute perception of the risks associated with CPUWDriving and appeared to be concerned, as a whole, with social risks related to I-Incivility. They do not appear particularly concerned by the risks related to LIMRadiation, which may reflect societal confusion about risks still considered as hypothetical and/or based on equivocal evidence. Gender, ethnicity, and age were not predictive for perceived risks. Level of schooling had a positive influence on perceived risks related to CPUWDriving and I-Incivility, and cell-phone ownership had an inverse relationship with perceived risks related to I-Incivility.
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Cécile Martha, Jean Griffet (2007)  Risk taking and risk perception in road safety: comparative study of young sportsmen and nonsportsmen in southeastern France.   Percept Mot Skills 104: 3 Pt 2. 1243-1250 Jun  
Abstract: The relationship between participation in sporting activity and both risk taking and risk perception when traveling on a two-wheeled vehicle were evaluated among 614 adolescents between the ages of 14 and 17 years. The sex of the respondents (252 girls, 362 boys) and their experience with road accidents were taken into account. Three-way analyses of variance indicated a significant main effect for sex, with girls reporting both fewer risky behaviors and higher risk perception than boys when traveling on a two-wheeled vehicle. Effect for sporting activity was also significant, with sports practitioners reporting lower risk taking and higher risk perception than nonsportsmen. There was also a significant interaction between sex and sporting activity. For boys, risk taking was higher and risk perception lower among the nonsportsmen than among the sports practitioners. Experience with road accidents had no significant relationship with risk taking or risk perception when traveling on a two-wheeled vehicle.
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2006
C Martha, M Coulorr, M Souville, J Griffet (2006)  [Risks linked to mobile phone use and how they are portrayed in the media: examples from three daily newspapers].   Sante Publique 18: 2. 275-288 Jun  
Abstract: This study analyses how three French daily newspapers (Liberation, Le Monde, Le Figaro) convey information on the risks associated with mobile phone use in the period from 1995 to 2002. Quantitatively, the physical risks inherent to the low-intensity, electro-magnetic waves are most frequently reported, followed by those linked to mobile phone use while driving. "Social" risks, such as those related to noise or uncivil behaviour, are amongst the most rarely communicated. In general, the media present two types of physical risks connected to mobile phone use: the collective ones, which cover the low-intensity electro-magnetic waves which are emitted from the antennas on signal base stations, and the individual ones, which concem the waves produced by the mobile phone itself, and the danger associated with its use by a driver while operating a motor vehicle. Controversy surrounding the current scientific studies and the uncontrollable character of the risks linked to the low-intensity, electro-magnetic waves instill much more fear and debate than around those related to the combination of driving while talking on the telephone. While this latter point is scientifically proven, it is also subjectively under control.
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2004
J Griffet, J Habre, A Abou-Daher, T El Hayek (2004)  [Talus bipartitus].   Rev Chir Orthop Reparatrice Appar Mot 90: 4. 369-371 Jun  
Abstract: Talus bipartitus is an exceptional congenital malformation consisting in the presence of two non-fused bony talar fragments. We report the case of an adolescent girl who complained of mechanical pain in the left ankle which became increasingly invalidating. Plain radiographs, CT-scan and MRI led to the diagnosis of this congenital anomaly: talus bipartitus. Surgical correction by subtalar arthrodesis provided improvement at the cost of reduced ankle mobility. Surgical treatment should be proposed for talus bipartitus in patients with invalidating pain or stiffness when rehabilitation fails to provide sufficient improvement.
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Toni El Hayek, Ahmad Abou Daher, Wissam Meouchy, Paul Ley, Nizar Chammas, Jacques Griffet (2004)  External fixators in the treatment of fractures in children.   J Pediatr Orthop B 13: 2. 103-109 Mar  
Abstract: New properties are being modified in the external fixator instrumentation that are leading to the more indicated use of this type of fixation especially in children's lower limb fractures. Dynamization, the ability to lengthen the limb and easy wound care are among the new properties of the monoplane external fixator, along with greater stability than older models. These new properties are now making the external fixator an indication rather than a choice in many cases. We have retrospectively studied 21 children with lower limb fractures treated by 28 external fixators. The results of this study show advantages such as lower infection rate, consolidation without the need of reoperation, easy physiotherapy, easy wound care and the ability to perform shortening and lengthening in the same set. Disadvantages are mostly complications that are due to the external fixation such as iatrogenic vascular lesions, pins tract infections and iatrogenic fractures.
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Fabrice O Lorente, Marc Souville, Jean Griffet, Laurent Grélot (2004)  Participation in sports and alcohol consumption among French adolescents.   Addict Behav 29: 5. 941-946 Jul  
Abstract: Using an anonymous self-report questionnaire (N=816 participants), we examined the relation between participation in sports and alcohol consumption and identified the risk factors associated with alcohol consumption among French high-school students. Univariate analysis showed that sport involvement was related to higher alcohol use (P<.05). Participants who participated in group sports drank significantly more than those who participated as individuals (P<.01). Multivariate analysis underlined factors associated with alcohol consumption, but these varied considerably according to the level of alcohol consumption. Three factors were associated with weekly and daily alcohol use: male gender, daily cigarette use, and perception of poor health.
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2003
Fabrice O Lorente, Patrick Peretti-Watel, Jean Griffet, Laurent Grélot (2003)  Alcohol use and intoxication in sport university students.   Alcohol Alcohol 38: 5. 427-430 Sep/Oct  
Abstract: To investigate patterns of alcohol consumption and intoxication in French sport science students.
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2002
J Griffet, F Bastiani-Griffet, T El-Hayek, C Dageville, B Pebeyre (2002)  Management of seat-belt syndrome in children. Gravity of 2-point seat-belt.   Eur J Pediatr Surg 12: 1. 63-66 Feb  
Abstract: We present our experience with a management of seat-belt syndrome in three children and draw particular attention to the severity of two-point fixation seat-belt injuries after a motor vehicle accident with 5 passengers whose vehicle was struck head-on by an oncoming vehicle. The parents were sitting in front, Adeline had a 2-point lap seat-belt, the 2 other children had 3-point seat-belts. The parents both had humerus fractures. The 4-year-old brother suffered a cervical and abdominal trauma with renal and splenic contusions and intestinal perforations. Adeline suffered multiple injuries, notably to the head, spine and abdominal viscera with erosions at the site of lap-seat-belt contact. The spinal injury was an L2 angular Chance fracture associated with paraplegia on the 7th day. Operative findings included a transverse tear of the left rectus abdominus muscle, an incomplete transection of the stomach and perforation of the ileum. The injuries were ultimately fatal. Given associated abdominal pain, skin erosions at the site of seatbelt contact, spinal fracture, and rectal muscle disruption apparent on emergency laparotomy, early diagnosis is important for better prognosis.
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2001
K F Zabjek, M A Leroux, C Coillard, X Martinez, J Griffet, G Simard, C H Rivard (2001)  Acute postural adaptations induced by a shoe lift in idiopathic scoliosis patients.   Eur Spine J 10: 2. 107-113 Apr  
Abstract: The objective of this study was to identify acute spinal and three-dimensional postural adaptations induced by a shoe lift in a population of idiopathic scoliosis (IS) patients. Forty-six IS patients (mean age: 12 +/- 2 years) were evaluated radiologically and with a stereovideographic system for pelvic obliquity. Based on the initial postural and radiological evaluation, a pertinent shoe lift height was chosen for each with the result that 12 patients were tested with 5-mm (S5) lifts, 20 patients were tested with 10-mm (S10) lifts, and 14 patients with 15-mm (S15) lifts. The posture for all 46 patients was then re-evaluated and a spinal radiograph obtained for 14 patients. The implementation of a shoe lift independent of the type of curve and amplitude significantly decreased the Cobb angle. As expected there was a change in the vertical height of the left tibial plateau and greater trochanter that induced a change in pelvic tilt. There was also a significant increase in the vertical height of S1 and T1. There was a significant change in the left and right iliac bone version, as well as a decrease in the difference in version between these two bones. The implementation of the shoe lifts also changed the lateral shift of the pelvis. A relative change between the shoulders and pelvis for tilt and anteroposterior shift was also found to be significant. In conclusion, using a shoe lift resulted in acute postural adaptations which specifically affected the spine and the three-dimensional position and orientation of the pelvis and shoulder girdle.
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2000
N Sirvent, F Fisher, T el Hayek, A Appert, H Giudicelli, J Griffet (2000)  Absence of congenital prethrombotic disorders in children with Legg-Perthes disease.   J Pediatr Orthop B 9: 1. 24-27 Jan  
Abstract: Resistance to activated protein C (RPCA) and other congenital prethrombotic disorders have been recently reported to be strongly associated with Legg-Perthes disease. RPCA and deficiencies of protein C, protein S, and antithrombin III were sought in 22 children with Legg-Perthes disease. Detection of the factor V Leiden mutation was found in children with RPCA. Twenty-two healthy children paired by age and sex served as controls. The prevalence of congenital prethrombotic disorders was not found to differ significantly among patients with Legg-Perthes disease and among control subjects. Only one patient had RPCA; this patient was heterozygous for the factor V Leiden mutation. Twenty patients and all the control subjects had entirely normal coagulation results. The authors conclude that unless more data become available, RPCA and deficiencies of protein C, protein S, and antithrombin III should not be considered associated with Legg-Perthes disease.
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J Griffet, F Bastiani-Griffet, S Jund, M Moreigne, K F Zabjek (2000)  Duplication of the leg--renal agenesis: congenital malformation syndrome.   J Pediatr Orthop B 9: 4. 306-308 Oct  
Abstract: A case is given of a male born with a duplication of the left leg and ipsilateral kidney agenesis. Although the etiology is unknown, we believe this association represents a congenital malformation syndrome. It is a polytopic developmental field defect. The growth factor IGF-I produced by the intermediary mesoderm or mesonephros (embryonary kidney) could be implicated in the induction limb development and the application of FGF-8 protein to the flank of young chick embryos inducing the development of additional limbs. It is possible that one or more of the growth factors produced by the mesonephros take some cells of the intermediary mesoderm out of their renal way to form a supernumerary limb.
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J Griffet, M A Leroux, J Badeaux, C Coillard, K F Zabjek, C H Rivard (2000)  Relationship between gibbosity and Cobb angle during treatment of idiopathic scoliosis with the SpineCor brace.   Eur Spine J 9: 6. 516-522 Dec  
Abstract: The objective of this study was to quantify the relationship between gibbosity and spinal deformation expressed by the angle of Cobb before and during treatment with a brace for different classes of idiopathic scoliosis patients. As part of the standard treatment with the Dynamic Corrective Brace (SpineCor), 89 idiopathic scoliosis patients underwent an initial radiological examination and gibbosity measurement with a scoliometer wearing and not wearing the brace. The 89 patients were classified in relation to the apex of the scoliosis curves: thoracic (n = 29); thoracolumbar (n = 40); lumbar (n = 7) and double (n = 13). With the dynamic corrective brace, the patients showed a mean decrease of 8.3 degrees for the major Cobb angle, and a mean decrease of 2.3 degrees for their gibbosity. There was a significant positive relationship between gibbosity and Cobb angle with and without the brace for the thoracic and thoracolumbar curves. A linear regression analysis identified a small mean estimation error for the thoracic curves (7.4 degrees no-brace; 2.7 degrees with brace) and thoracolumbar curves (5.2 degrees no-brace; 5.3 degrees with brace), indicating a predictive potential of the scoliometer. The measure of gibbosity with the scoliometer provides a fairly reliable estimation of Cobb angle at the initial clinical examination of a scoliosis patient. However, when initial Cobb angle and gibbosity are considered, the measure of gibbosity when wearing a brace provides the clinician with a highly reliable estimation of the Cobb angle while in a brace. This relationship also exists for the follow-up with a brace, permitting a judgement of the patient's evolution under the treatment with SpineCor.
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1999
J Griffet, A Chevallier, T El Hayek, G Odin, B Pebeyre, E Accorsi (1999)  Diaphyseal fractures treated by polylactide and hydroxyapatite pins. Experimental study in rat.   J Mater Sci Mater Med 10: 7. 411-418 Jul  
Abstract: In order to develop a biodegradable interlocking nail for fracture fixation, polylactic acid (PLA) pins and hydoxyapatite pins were implanted in the femoral bone in rats. A distal fracture was performed. The union and the tissue reaction to PLA and hydroxyapatite versus stainless steel rods were studied after 15 days, 1, 2 and 6 months implantation. Metal and PLA pins induced a union. Hydroxyapatite pins (Ossatite) did not prevent callus formation, but did not lead to consolidation in all cases because of weakness of the gelatin matrix binding the apatite particles together. PLA and stainless steel pins induced the same union and a similar tissue reaction during the studied implantation of 6 months. The biocompatility of Ossatite is satisfactory and the osteo-inductive properties of hydroxyapatite was confirmed. With injectable Ossatite, we could not obtain rat femoral fracture consolidation. We can confirm good biomaterial tolerance in bone which contrasts with important soft tissue reactions. Use of such material should be carefully limited to filling intra-osseous cavities.
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J Griffet, A Chevallier, E Accorsi, T El Hayek, G Odin, B Pebeyre (1999)  Osteosynthesis of diaphyseal fracture by Ossatite experimental study in rat.   Biomaterials 20: 6. 511-515 Mar  
Abstract: In order to develop a biodegradable interlocking nail for fracture fixation, hydoxylapatite pins and paste were implanted in the femoral bone of rats. A distal fracture was performed. The union and the tissue reaction to hydroxylapatite versus stainless-steel rods were studied after 15 days, 1, 2 and 6 months implantation. Metal pins induced a union. Hydroxylapatite pins (Ossatite) did not prevent callus formation, but did not lead to consolidation in all cases due to weakness of gelatin matrix binding the apatite particles together. The biocompatibility of material is satisfactory and the osteo-inductive properties of hydroxylapatite was confirmed. With injectable Ossatite , we could not obtain rat femoral fracture consolidation. We can confirm good biomaterial tolerance in bone which contrasts with important soft tissue reactions. Use of such material should be carefully limited to filling intra-osseous cavities.
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J Griffet, T el Hayek, M Baby (1999)  Intramedullary nailing of forearm fractures in children.   J Pediatr Orthop B 8: 2. 88-89 Apr  
Abstract: Forearm fractures are very common in children. They are usually treated orthopedically. For the last few years, Métaizeau's elastic stable nailing has been used in the authors' hospital. This study is based on 80 children with forearm fractures treated with intramedullary nailing: 64 boys and 16 girls, aged 6 to 16 (23 right sides, 58 left sides: 81 fractures). Nailing was performed 67 times for a displaced fracture, 3 times for a recurrent fracture, 3 times after a secondary displacement, and 7 times in patients with multiple injuries. Sound union was normally achieved in 78 patients, and normal motion in 79. Ten children experienced complications, but only complications involving the skin and sepsis were due to the technique. The seven skin complications (three in the ulnar fractures, and four in the radial fractures) consisted of three major local infections, one radial osteomyelitis, and three minor local nonunion of skin. One patient had limited thumb extension, and two patients fell a second time. One advantage of the method described here is that plaster casts are avoided, allowing children to go back to school early. Sound union is achieved as quickly as with orthopedic treatment, and recovery is excellent.
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1998
J Griffet, J Thévenot, F Barral (1998)  Presentation of GTB orthoses for hyperlordotic treatment of idiopathic scoliosis.   Eur J Pediatr Surg 8: 3. 163-167 Jun  
Abstract: Screening of scoliosis means it is possible to make an early diagnosis. Treatment is started when the angle reading is still quite low but as soon as it has been proven that the scoliosis is progressive. A 3-D examination of the scoliosis makes it possible to have a better understanding of its development, which is in kyphosis at lumbar level and in lordosis at thoracic level. It would seem logical that in order to prevent a lumbar scoliosis becoming kyphotic, lordosis must be maintained and if necessary, a hyperlordosis created. The same applies to the thoracic curve when attempting to restore a thoracic kyphosis with a lumbar hyperlordosis. We have developed new orthoses with the correction principle based on creating a lumbar hyperlordosis. Correction of the translation is the second correction principle. In theory, correction involves: a translation (convex lateral pressure) and a hyperlordosis which puts back in place the convex articular facet (posterior pressure). With these two principles in mind, the aim of the orthosis is to invert the torsion movement and to avoid pressure in the opposite direction of the deformity. We have maintained the principle of a single shell made of ribbed polypropylene to produce a brace which is both light and strong. There are three types of models depending on the spine curve: the short GTB 1 brace for lumbar curves, the long GTB 2 brace for thoracic and double curves, the long or short GTB 3 brace depending on the upper end vertebra for thoraco-lumbar curves.
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M Lonjon, P Paquis, J F Michiels, J Griffet, P Grellier (1998)  Endodermal cyst of the foramen magnum: case report and review of the literature.   Childs Nerv Syst 14: 3. 100-103 Mar  
Abstract: The majority of endodermal cysts occur in the cervicothoracic spine, ventral to the cord. Intracranial locations are rare. We report a case involving the foramen magnum in a 14-year-old child, which was an incidental finding following a traumatic head injury. A review of the literature revealed six other cases involving this same location. These lesions are asymptomatic for a long time, and may cause brain stem medullary compression. Treatment is surgical. Effective simple removal can be achieved by a posterior approach.
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J Griffet, T el Hayek, P Giboin (1998)  Melorheostosis: complications of a tibial lengthening with the Ilizarov apparatus.   Eur J Pediatr Surg 8: 3. 186-189 Jun  
Abstract: Melorheostosis is a rare bone dysplasia, exceptionally described in childhood. It has been discovered in a 12-year-old boy who had a hemimelic affection associated with straw-berry skin marks. A 25 mm inequality of length of the lower limbs and a valgus deformation of the ankle resulting in a claudication and gonalgia requiring surgical correction. A reaxation and a progressive lengthening with the Ilizarov apparatus has been performed. Non-consolidation and a secondary bone infection led to the necessity of formation of a soleus flap. Consolidation and healing were finally obtained. In addition to vascular complications to be feared in this disease during surgical treatment, we have to take into consideration the absence of consolidation when the osteotomy is not performed on a safe bone.
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1996
J Griffet, T El Hayek (1996)  [Percutaneous drainage of septic hip arthritis in children].   Rev Chir Orthop Reparatrice Appar Mot 82: 3. 251-254  
Abstract: Hip arthritis is a therapeutic emergency which requires sure diagnosis and pus evacuation. Two methods are presently in use: isolated or oriterative punction and arthrotomy.
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1994
P A Giordano, J Griffet, C Argenson (1994)  Pedicled greater omentum transferred to the spine in a case of postoperative infection.   Plast Reconstr Surg 93: 7. 1508-1511 Jun  
Abstract: An alternate surgical treatment was proposed in a case of vertebral postoperative chronic infection. The combination of an anterior omental flap with a posterior internal fixation plus bone grafting was successful, allowing the patient to walk 8 weeks after surgery. This relatively short recovery period compares favorably with the long months of confinement to bed usually required after an all-anterior approach with bone grafting only.
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1992
J Griffet, F Bastiani, P Hofman, C Argenson (1992)  [Prevention of scar formation by polyglactin 910 (Vicryl) mesh after lumbar laminectomy in the rat].   Rev Chir Orthop Reparatrice Appar Mot 78: 6. 365-371  
Abstract: Laminectomy in lumbar spine surgery often produces disabling adhesive arachnoiditis. We have tested, on the rat, polyglactin 910 mesh with collagen or not, with a mail 0.9 mm large. We have used 34 Wistar male rats. L5 laminectomy were realised on all the rats. Rats were ranged in four groups: group 1: control, L5 laminectomy alone, 6 months follow up--group 2: one month follow up, L5 laminectomy, vicryl mesh with collagen or not--group 3: two months follow up, L5 laminectomy, vicryl mesh with collagen or not--group 4: six months follow up, L5 laminectomy, vicryl mesh with collagen or not. On 28 rats, the histologic study have demonstrated: group 1 control: important and adhesive fibrosis scar--group 2: no or minimal reaction--group 3: fibroblastic or few cellular, non or little adhesive fibrosis--group 4: moderate adhesive fibrosis in half of the cases with vicryl mesh without collagen, minimal non adhesive fibrosis with collagen vicryl mesh.
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1991
1990
J Griffet, F Bastiani, J F Michiels (1990)  [Post-traumatic spinal arachnoid cyst].   Chir Pediatr 31: 2. 131-133  
Abstract: A 15 year old boy presents two fractures of the left inferior member (femur and tibia), after a motor-cycle accident. An osteosynthesis by plate and screws was performed, in emergency. In immediate post-operative days, a radicular paresia of the left inferior member appear especially on exterior popliteus sciatic nerve. The electromyogram confirm the diagnosis. However, these is nor pain nor fracture of the sacro-lumbar spine. The consolidation of femur and tibia fractures is normal. The neurologic recuperation is slow but progressive. A year after the accident, because the recuperation is not complete, an MRI is performed. An arachnoidal cyst surrounding the L5 and S1 roots is diagnosed. The surgery is decided. The ablation of the cyst is performed in the same operative time that the ablation of plate. The histology of the paries of the cyst confirm, by hemosiderimic deposits, the traumatic etiology. The arachnoïdal cyst is rare, particularly in the childhood. It is always difficult to know the relation between the cyst and the symptom. It is also impossible to be certain of traumatic etiology: traumatic cyst or traumatised cyst? The surgical indication is lawful by the existence of clinical signs, because 50 per cent of cases are improved or recovered.
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F Bastiani-Griffet, G Bollini, J Berard, J Griffet, J M Bouyala (1990)  [Pygomelus. Apropos of 2 cases and a review of the literature].   Chir Pediatr 31: 6. 333-336  
Abstract: The authors report two rare cases of pygomelus monster. The appearance and operative procedures undertaken are described. Pygomelus and caudal duplication are often mixed in literature. This monstruosity is classified in the twin monsters, but minor forms any be discussed with sacro-coccygeal teratomas and reduplication of lower limbs.
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C Argenson, M Frehel, J Lovet, J Griffet, F Deperetti (1990)  [Severe cervical spinal cord injuries without traumatic osteo-disco-ligamentous lesion].   Rev Chir Orthop Reparatrice Appar Mot 76: 7. 507-518  
Abstract: The existence of cervical spinal cord injury without bony nor disco-ligamentous lesion rises pathogenic, prognostic and therapeutic challenges. The extent and localisation of cord injury, which depends on intensity and direction of the applied force, can explain the different clinical patterns: incomplete quadriplegia: 8 cases, incomplete Brown-Sequard-like quadriplegia: 2 cases, diplegia brachialis: 5 cases. We have not observed any complete quadriplegia. The presence of arthritic or congenital spinal canal stenosis has been found in 12 cases. We have used a coupled myelographic-CT Scan study. MRI has been employed more recently. This X-ray study has never found any major cord compression. Improvement of neurologic troubles, under medical treatment, was constant, but sequelae were always present, hands being most concerned; their importance was paralleled to the initial clinical feature. The Brown-Sequard-like quadriplegia were more pejorative. 3 patients, after an initial improvement, have presented a cervical myelopathic evolution and have been successfully operated on. On the other hand, the only initially operated on patient has been immediately worsened. Operation is indicated by the third week, when coexist: a spinal stenosis and a poor clinical evolution.
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1989
C Argenson, J Griffet, C Lacour, H Arcamone, J Lovet, F de Peretti (1989)  [Vertebral hydatid cyst. Apropos of 2 cases].   Rev Chir Orthop Reparatrice Appar Mot 75: 4. 267-270  
Abstract: The hydatid disease is rare in osseous locations, especially in our country (2.2 per cent). It has some particularities: clinical latency, diagnosis difficulties, surgical treatment often unsatisfactory because of the difficulty of total excision. Pain and sometimes deformity are often the only clinical features at the beginning of the disease. But, the evolution is unfavourable as soon as neurological symptoms appear. Multiple recurrences lead to unavoidable paraplegia. The antihelminthic drug (mebendazole) is disappointing in osseous location. Surgery is the only hope but the excision must be carcinologic. Spinal instrumentation can be improved by the use of acrylic cement whereas osseous grafts can be invaded by hydatidosis extension or recurrence. At present, the prognosis is still poor with constant apparition of cord compression. The authors report two cases of patients with osseous hydatidosis of the spine which illustrate these difficulties.
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J Griffet, J Darcourt, F Lapalus, C Cougnot, R Mariani (1989)  [Specificity and indications of bone scan in non-neoplastic bone and joint disease in children. A study of seventy cases].   Ann Pediatr (Paris) 36: 10. 675-679 Dec  
Abstract: We studied 70 bone scans in pediatric patients to define the indications of this procedure in non-neoplastic disease. Sensitivity of bone scans in infections proved outstanding except in children under one year of age. Eighty-nine per cent of children with pain and fever and a positive bone scan had either an infection or osteochondritis. The same symptoms with a negative bone scan indicated either transient synovitis of the hip or the absence of bone lesions in 83% of cases. Children with pain as the only symptoms and a negative bone scan consistently had either transient synovitis of the hip, or normal bones and joints (100% of cases). Eighty-two per cent of children with pain and a positive bone scan had an infection or osteochondritis. Indications of bone scanning vary according to clinical features and include all children with functional impairment, pain and fever, and isolated limps with no obvious cause.
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1988
1987
J Griffet, F Bastiani (1987)  [Fracture of the lumbar spine in a child, simulating Scheuermann's disease].   Chir Pediatr 28: 4-5. 259-261  
Abstract: The association of a low back pain and kyphosis in children has not a unique diagnosis. A type of fracture of lumbar spine in the child simulates Scheuermann's disease. As in Scheuermann's disease, a traumatic event in sport is frequently associated with the onset of symptoms. But the location of intraspongious herniation to the anterior margin of vertebral body signs the fracture of lumbar spine.
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1986
J Griffet, M Albertini, F Bastiani, T Bourrier, R Mariani (1986)  [Spondylodiscitis in children following lumbar puncture. Apropos of a case].   Chir Pediatr 27: 6. 354-355  
Abstract: We described a case of spondylodiscitis L3 L4, in a 3 year old child that appeared 3 weeks after a lumbar puncture. The infectious agent responsible wasn't found. The child recovered without sequelae with an antistaphylococcis treatment. The mecanism by inoculation has been described after surgery of the inter-vertebral disc but also after spinal anesthesis. The bone complications of the lumbar puncture are exceptionally rare but elementary aseptic precautions must not be overlooked in order minimise the infection.
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P Grellier, J L Roche, J Griffet, P Paquis, J Duplay, P Ballester (1986)  [The narrow lumbar canal. Study of a surgical series of 139 cases].   Neurochirurgie 32: 6. 471-476  
Abstract: Over a period of 9 years, 139 patients with a mean age of 61 years were operated upon for disorders due to narrow lumbar vertebral canal. Clinical expression varied: lumbago, movement sciatica, intermittent claudication... Importance must be attached to discordance of examination findings in apparently benign root pain (67% of cases). The two key examinations of radiologic investigation are radiculography and a CT scan. Treatment is surgical, generally by a two-stage wide laminectomy combined with abrasion of an articular facet (64%), excision of osteophytic pads (35%) and/or treatment for a soft herniated disc (26%). Recovery was obtained in 35% of cases and pronounced improvement in 49% (84% of very good and good results) as evaluated by patients and surgeons.
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J Griffet, J Berard, C R Michel, J Caton (1986)  [Congenital superior radioulnar synostoses. A study of 43 cases].   Int Orthop 10: 4. 265-269  
Abstract: Superior radioulnar synostosis is a rare abnormality which frequently gives rise to functional disability. Its pattern of inheritance is uncertain. We have studied 29 children, 18 boys and 11 girls, who had a total of 43 such synostoses. Twenty children had significant functional disability. Fourteen required operation, 10 undergoing a Judet's osteotomy and 4 osteotomy of the lower end of the radius. The dominant hand was placed in the position of function, and the other in 30-40 degrees of supination. The osteotomies were secured by pins and supported in a plaster splint. Use of the forearm and hand was improved in all cases. Operation is best carried out between the ages of 4 and 10, and a useful functional improvement can be expected.
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J Griffet, J Bérard, J F Fredenucci, F N Guillermet (1986)  [Osteitis due to anaerobic Corynebacteria in children. Apropos of 4 cases].   Rev Chir Orthop Reparatrice Appar Mot 72: 4. 311-316  
Abstract: The authors have seen four instances in children of osteitis due to a mycobacterium. The disease was subacute and situated in the tibia, the lumbar spine, the talus and the femur. In two cases the diagnosis was eventually mistakenly oriented towards tuberculosis or a malignant tumour. The correct diagnosis was obtained after a bone biopsy which demonstrated a granulomatous osteitis. In such cases there is an indication for a full biopsy and bacteriological examination with culture in aerobic and anaerobic media. Treatment based on pristinamycin resulted in healing.
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1985
J S Valla, F Bastiani, J Griffet, D Louis, M Jaubert de Beaujeu (1985)  [Digestive stenosis after neonatal enterocolitis].   Chir Pediatr 26: 6. 331-339  
Abstract: Nineteen clinical cases of intestinal stricture due to neonatal necrotising enterocolitis and a review of available references are presented in this paper. Intestinal strictures are estimated to arise in 20% to 30% on neonatal enterocolitis. However the delay between the acute episode and the occurrence of the stenosis is variable; the depth and the extend, of the necrosis as well as inflammation and superinfection may contribute to the building up of the intestinal stricture. The histological aspects of the lesions are not unique, more over cases of spontaneously regressive stenosis are known. Question thus arising as to the most appropriate timing for surgery and the choice of surgical technics as a function of clinical aspects and of derivation of the disease are discussed in this paper.
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J Griffet, J L Roche, P Grellier, J Duplay (1985)  [Epidermoid cysts of the cranial vault in children. Apropos of 6 cases].   Pediatrie 40: 7. 561-564 Oct/Nov  
Abstract: Six observations of epidermoid cysts of the cranial vault in children are reported. The main clinical sign is a cranial tumefaction; the radiological data consist in an edged osseous gap; the surgical extraction of this evolutional tumor is indicated.
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