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Murtaza
Tambuwala
mtambuwala@gmail.com
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Journal articles
2016
DOI
PMID
Miguel A S Cavadas
,
Marion Mesnieres
,
Bianca Crifo
,
Mario C Manresa
,
Andrew C Selfridge
,
Ciara E Keogh
,
Zsolt Fabian
,
Carsten C Scholz
,
Karen A Nolan
,
Liliane M A Rocha
,
Murtaza M Tambuwala
,
Stuart Brown
,
Anita Wdowicz
,
Danielle Corbett
,
Keith J Murphy
,
Catherine Godson
,
Eoin P Cummins
,
Cormac T Taylor
,
Alex Cheong
(2016)
REST is a hypoxia-responsive transcriptional repressor.
Scientific reports
6:
08.
DOI
PMID
Murtaza M Tambuwala
(2016)
Natural Nuclear Factor Kappa Beta Inhibitors: Safe Therapeutic Options for Inflammatory Bowel Disease.
Inflammatory bowel diseases
22:
3.
719-723
Mar.
DOI
PMID
Susan F Fitzpatrick
,
Zsolt Fábián
,
Bettina Schaible
,
Colin R Lenihan
,
Thomas Schwarzl
,
Javier Rodriguez
,
Xingnan Zheng
,
Zongwei Li
,
Murtaza M Tambuwala
,
Desmond G Higgins
,
Yvonne O'Meara
,
Craig Slattery
,
Mario C Manresa
,
Peter Fraisl
,
Ulrike Bruning
,
Myriam Baes
,
Peter Carmeliet
,
Glen Doherty
,
Alex von Kriegsheim
,
Eoin P Cummins
,
Cormac T Taylor
(2016)
Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.
Biochemical and biophysical research communications
474:
3.
579-586
Jun.
2015
DOI
PMID
Lan K Nguyen
,
Miguel A S Cavadas
,
Carsten C Scholz
,
Susan F Fitzpatrick
,
Ulrike Bruning
,
Eoin P Cummins
,
Murtaza M Tambuwala
,
Mario C Manresa
,
Boris N Kholodenko
,
Cormac T Taylor
,
Alex Cheong
(2015)
A dynamic model of the hypoxia-inducible factor 1a (HIF-1a) network.
Journal of cell science
128:
2.
Jan.
DOI
PMID
Murtaza M Tambuwala
,
Mario C Manresa
,
Eoin P Cummins
,
Vincenzo Aversa
,
Ivan S Coulter
,
Cormac T Taylor
(2015)
Targeted delivery of the hydroxylase inhibitor DMOG provides enhanced efficacy with reduced systemic exposure in a murine model of colitis.
Journal of controlled release : official journal of the Controlled Release Society
217:
221-227
Nov.
2013
DOI
PMID
Lan K Nguyen
,
Miguel A S Cavadas
,
Carsten C Scholz
,
Susan F Fitzpatrick
,
Ulrike Bruning
,
Eoin P Cummins
,
Murtaza M Tambuwala
,
Mario C Manresa
,
Boris N Kholodenko
,
Cormac T Taylor
,
Alex Cheong
(2013)
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
Journal of cell science
126:
Pt 6.
1454-1463
Mar.
DOI
PMID
Carsten C Scholz
,
Miguel A S Cavadas
,
Murtaza M Tambuwala
,
Emily Hams
,
Javier Rodríguez
,
Alex von Kriegsheim
,
Philip Cotter
,
Ulrike Bruning
,
Padraic G Fallon
,
Alex Cheong
,
Eoin P Cummins
,
Cormac T Taylor
(2013)
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America
110:
46.
18490-18495
Nov.
2011
DOI
PMID
Susan F Fitzpatrick
,
Murtaza M Tambuwala
,
Ulrike Bruning
,
Bettina Schaible
,
Carsten C Scholz
,
Annette Byrne
,
Aisling O'Connor
,
William M Gallagher
,
Colin R Lenihan
,
John F Garvey
,
Katherine Howell
,
Padraic G Fallon
,
Eoin P Cummins
,
Cormac T Taylor
(2011)
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia.
Journal of immunology (Baltimore, Md. : 1950)
186:
2.
1091-1096
Jan.
DOI
PMID
Ulrike Bruning
,
Luca Cerone
,
Zoltan Neufeld
,
Susan F Fitzpatrick
,
Alex Cheong
,
Carsten C Scholz
,
David A Simpson
,
Martin O Leonard
,
Murtaza M Tambuwala
,
Eoin P Cummins
,
Cormac T Taylor
(2011)
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia.
Molecular and cellular biology
31:
19.
4087-4096
Oct.
DOI
PMID
Emily Hams
,
Sean P Saunders
,
Eoin P Cummins
,
Aisling O'Connor
,
Murtaza T Tambuwala
,
William M Gallagher
,
Annette Byrne
,
Antonio Campos-Torres
,
Paul M Moynagh
,
Christian Jobin
,
Cormac T Taylor
,
Padraic G Fallon
(2011)
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells.
Shock (Augusta, Ga.)
36:
3.
295-302
Sep.
2010
DOI
PMID
Murtaza M Tambuwala
,
Eoin P Cummins
,
Colin R Lenihan
,
Judit Kiss
,
Markus Stauch
,
Carsten C Scholz
,
Peter Fraisl
,
Felix Lasitschka
,
Martin Mollenhauer
,
Sean P Saunders
,
Patrick H Maxwell
,
Peter Carmeliet
,
Padraic G Fallon
,
Martin Schneider
,
Cormac T Taylor
(2010)
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Gastroenterology
139:
6.
2093-2101
Dec.
2009
DOI
PMID
Kathleen A O'Hagan
,
Sinead Cocchiglia
,
Alexander V Zhdanov
,
Murtaza M Tambuwala
,
Murtaza M Tambawala
,
Eoin P Cummins
,
Mona Monfared
,
Terence A Agbor
,
John F Garvey
,
Dmitri B Papkovsky
,
Cormac T Taylor
,
Bernard B Allan
(2009)
PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells.
Proceedings of the National Academy of Sciences of the United States of America
106:
7.
2188-2193
Feb.
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All Tags:
129 Strain
,
Administration
,
alpha Subunit
(4),
Amino Acids
(2),
Analysis of Variance
,
Animal
(2),
Animals
(6),
Anoxia
(3),
Apoptosis
(2),
Biological
(2),
Blotting
,
Caco-2 Cells
(2),
Cell Hypoxia
,
Cells
(2),
Colitis
(2),
Colon
,
Computational Biology
,
Cultured
(2),
Cyclooxygenase 2
,
Dextran Sulfate
(2),
Dicarboxylic
(2),
Dioxygenases
,
Disease Models
(2),
Drug Delivery Systems
,
Enterocytes
,
Enzymologic
,
Epithelial Cells
,
Female
(2),
Fibroblasts
,
Firefly
,
Flow Cytometry
,
Gene Expression Regulation
(4),
Heat-Shock Proteins
,
HEK293 Cells
,
HeLa Cells
(3),
Humans
(7),
Hydroxylation
,
Hypoxia
,
Hypoxia-Inducible Factor 1
(4),
Hypoxia-Inducible Factor-Proline Dioxygenases
,
Immunoblotting
,
Immunoprecipitation
,
Inbred BALB C
,
Inbred C57BL
(2),
Inflammation
,
Inflammation Mediators
,
Interleukin-10
(2),
Interleukin-1beta
,
Intestinal Absorption
,
Intestinal Mucosa
,
Knockout
,
Lipopolysaccharides
,
Luciferases
(2),
Lung
,
Macrophages
,
Male
,
Mass Spectrometry
,
Mice
(13),
Microarray Analysis
,
MicroRNAs
,
Mitochondria
,
Mixed Function Oxygenases
(4),
Models
(2),
Muscle
,
Myocardium
,
NF-kappa B
(4),
NF-κB
,
Nuclear Proteins
,
Oral
,
Oxygen
(2),
Oxygen Consumption
,
Polymerase Chain Reaction
,
PPAR gamma
,
Procollagen-Proline Dioxygenase
,
Prolyl hydroxylase,
,
Prolyl Hydroxylases
,
Proteasome Endopeptidase Complex
,
Protein Stability
,
Proteolysis
,
Rats
,
Receptors
,
Repressor Proteins
,
RNA
,
RNA-Binding Proteins
,
Sepsis
,
Septic
,
Severity of Illness Index
,
Shock
,
Signal Transduction
(3),
Skeletal
,
Small Interfering
,
Trans-Activators
,
Transcription Factors
,
Transcriptional Activation
,
Transgenic
(2),
Treatment Outcome
,
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
,
Western
Authors
T Agbor
,
B Allan
,
V Aversa
,
M Baes
,
S Brown
,
U Bruning
(6),
A Byrne
(2),
A Campos-Torres
,
P Carmeliet
(2),
M Cavadas
(4),
L Cerone
,
A Cheong
(5),
S Cocchiglia
,
D Corbett
,
P Cotter
,
I Coulter
,
B Crifo
,
E Cummins
(11),
G Doherty
,
Z Fabian
,
P Fallon
(4),
S Fitzpatrick
(5),
P Fraisl
(2),
Z Fábián
,
W Gallagher
(2),
J Garvey
(2),
C Godson
,
E Hams
(2),
D Higgins
,
K Howell
,
C Jobin
,
C Keogh
,
B Kholodenko
(2),
J Kiss
,
A von Kriegsheim
(2),
F Lasitschka
,
C Lenihan
(3),
M Leonard
,
Z Li
,
M Manresa
(5),
P Maxwell
,
M Mesnieres
,
M Mollenhauer
,
M Monfared
,
P Moynagh
,
K Murphy
,
Z Neufeld
,
L Nguyen
(2),
K Nolan
,
A O'Connor
(2),
K O'Hagan
,
Y O'Meara
,
D Papkovsky
,
L Rocha
,
J Rodriguez
,
J Rodríguez
,
S Saunders
(2),
B Schaible
(2),
M Schneider
,
C Scholz
(7),
T Schwarzl
,
A Selfridge
,
D Simpson
,
C Slattery
,
M Stauch
,
M Tambawala
,
M Tambuwala
(12),
C Taylor
(11),
A Wdowicz
,
A Zhdanov
,
X Zheng
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