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{userid:"claude.ferec", "articletype":"article","pages":"1144-1149","author":"K Rouault, V Scotet, S Autret, F Gaucher, F Dubrana, D Tanguy, C Yaacoub El Rassi, B Fenoll, C F\u00e9rec","year":"2010","title":"Evidence of association between GDF5 polymorphisms and congenital dislocation of the hip in a Caucasian population.","month":"Sep","journal":"Osteoarthritis and cartilage \/ OARS, Osteoarthritis Research Society","publisher":"","volume":"18","number":"9","note":"","tags":"Adolescent,Adult,Alleles,Case-Control Studies,Child,Child, Preschool,European Continental Ancestry Group,Female,Gene Frequency,Genetic Predisposition to Disease,Genotype,Growth Differentiation Factor 5,Hip Dislocation, Congenital,Humans,Infant,Infant, Newborn,Male,Middle Aged,Polymorphism, Genetic,Young Adult","booktitle":"","editor":"","abstract":"Congenital dislocation of the hip (CDH) is a multifactorial disease which involves genetic factors that are still unidentified. Recently, a functional polymorphism (rs143383) of the 5'-untranslated region of GDF5 (Growth\/Differentiation Factor 5) - previously reported to be associated with osteoarthritis - has been associated with CDH in a Chinese population. The aim of our study was to determine whether GDF5, known to be involved in bone, joint and cartilage morphogenesis, is also associated with CDH in Caucasians.","address":"","school":"","issn":"1522-9653","doi":"10.1016\/j.joca.2010.05.018","isi":"","pubmed":"20633687","key":"Rouault2010","howpublished":"","urllink":"","refid":98,"weight":98}
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{userid:"claude.ferec", "articletype":"article","pages":"1099-1105","author":"K Rouault, V Scotet, S Autret, F Gaucher, F Dubrana, D Tanguy, C Yaacoub El Rassi, B Fenoll, C F\u00e9rec","year":"2009","title":"Do HOXB9 and COL1A1 genes play a role in congenital dislocation of the hip? Study in a Caucasian population.","month":"Aug","journal":"Osteoarthritis and cartilage \/ OARS, Osteoarthritis Research Society","publisher":"","volume":"17","number":"8","note":"","tags":"Case-Control Studies,Collagen Type I,Female,France,Genetic Predisposition to Disease,Genetic Variation,Genotype,Haplotypes,Hip Dislocation, Congenital,Homeodomain Proteins,Humans,Male,Polymorphism, Genetic,Risk Factors","booktitle":"","editor":"","abstract":"Congenital dislocation of the hip (CDH), which is one of the most common congenital skeletal disorders, corresponds to an abnormal seating of the femoral head in the acetabulum. It is commonly admitted that CDH presents a genetic component. However, little is known about the genetic factors involved. This study aimed to determine the role of two potential candidate genes on chromosome 17 in CDH: HOXB9 (involved in limb embryonic development) and COL1A1 (involved in joint laxity).","address":"","school":"","issn":"1522-9653","doi":"10.1016\/j.joca.2008.12.012","isi":"","pubmed":"19341834","key":"Rouault2009","howpublished":"","urllink":"","refid":130,"weight":130}
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{userid:"jean-francois.michaud", "refid":"3","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Ti-Ni ohmic contacts on 3C-SiC doped by nitrogen or by phosphorus implantation","year":"2010","author":"A.E. Bazin, J.F. Michaud, C. Autret-Lambert, F. Cayrel, T. Chassagne, M. Portail, M. Zielinski, E. Collard and D. Alquier","journal":"Materials Science and Engineering B","volume":"171","number":"","pages":"120","month":"","doi":"10.1016\/j.mseb.2010.03.084","pubmed":"","pdflink":"","urllink":"","abstract":"For electronic devices, good ohmic contacts are required. To achieve such contacts, the semiconductor layer has to be highly doped. The only method available to locally dope the SiC is to implant dopants in the epilayer through a mask. In this work, non-intentionally doped 3C\u2013SiC epilayers were implanted using nitrogen or phosphorus at different energies and subsequently annealed at temperatures between 1150 \u00b0C and 1350 \u00b0C in order to form n+ implanted layers. Different techniques such as Fourier Transformed InfraRed spectroscopy (FTIR), Secondary Ion Mass Spectroscopy (SIMS) and Transmission Electron Microscopy (TEM) were used to characterize implanted 3C\u2013SiC epilayers subsequently to the different annealing steps. Then, Ti\u2013Ni contacts were carried out and the specific contact resistance (\u03c1C) was determined by using circular Transfer Length Method (c-TLM) patterns. \u03c1C values were investigated as a function of implanted species and contact annealing conditions, and compared to those obtained for highly doped 3C\u2013SiC epilayers. As expected, \u03c1C value is highly sensitive to post-implantation annealing. This work demonstrates that low resistance values can be achieved using nitrogen or phosphorus implantation at room temperature hence enabling device processing.","note":"","tags":"","weight":"3"}
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{userid:"fernando.rannou", "refid":"8","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"GATE: a simulation toolkit for PET and SPECT.","year":"2004","author":"S Jan, G Santin, D Strul, S Staelens, K Assi\u00e9, D Autret, S Avner, R Barbier, M Bardi\u00e8s, P M Bloomfield, D Brasse, V Breton, P Bruyndonckx, I Buvat, A F Chatziioannou, Y Choi, Y H Chung, C Comtat, D Donnarieix, L Ferrer, S J Glick, C J Groiselle, D Guez, P F Honore, S Kerhoas-Cavata, A S Kirov, V Kohli, M Koole, M Krieguer, D J van der Laan, F Lamare, G Largeron, C Lartizien, D Lazaro, M C Maas, L Maigne, F Mayet, F Melot, C Merheb, E Pennacchio, J Perez, U Pietrzyk, F R Rannou, M Rey, D R Schaart, C R Schmidtlein, L Simon, T Y Song, J M Vieira, D Visvikis, R Van de Walle, E Wie\u00ebrs, C Morel","journal":"Physics in Medicine & Biology","volume":"49","number":"19","pages":"4543-4561","month":"Oct","doi":"","pubmed":"15552416","pdflink":"","urllink":"","abstract":"Monte Carlo simulation is an essential tool in emission tomography that can assist in the design of new medical imaging devices, the optimization of acquisition protocols and the development or assessment of image reconstruction algorithms and correction techniques. GATE, the Geant4 Application for Tomographic Emission, encapsulates the Geant4 libraries to achieve a modular, versatile, scripted simulation toolkit adapted to the field of nuclear medicine. In particular, GATE allows the description of time-dependent phenomena such as source or detector movement, and source decay kinetics. This feature makes it possible to simulate time curves under realistic acquisition conditions and to test dynamic reconstruction algorithms. This paper gives a detailed description of the design and development of GATE by the OpenGATE collaboration, whose continuing objective is to improve, document and validate GATE by simulating commercially available imaging systems for PET and SPECT. Large effort is also invested in the ability and the flexibility to model novel detection systems or systems still under design. A public release of GATE licensed under the GNU Lesser General Public License can be downloaded at http:\/www-lphe.epfl.ch\/GATE\/. Two benchmarks developed for PET and SPECT to test the installation of GATE and to serve as a tutorial for the users are presented. Extensive validation of the GATE simulation platform has been started, comparing simulations and measurements on commercially available acquisition systems. References to those results are listed. The future prospects towards the gridification of GATE and its extension to other domains such as dosimetry are also discussed.","note":"","tags":"Computer Simulation,Monte Carlo Method,Reproducibility of Results,Software,Thermodynamics,Tomography, Emission-Computed, Single-Photon","publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"0031-9155","isi":"","key":"Jan2004","howpublished":""}
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