// +author:f aboudan +author:aboudan var _ajax_res = { hits: 3, first: 0, results: [ {userid:"Dr_evers", "refid":"10","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Hemodialysis in metacresol poisoning.","year":"1994","author":"J Evers, F Aboudan, J Lewalter, E Renner","journal":"Clin Investig now J Mol Med","volume":"72","number":"","pages":"472","month":"","doi":"10.1007\/BF00180526","pubmed":"7950163","pdflink":"https:\/\/www.researchgate.net\/publication\/15249402_Hemodialysis_in_metacresol_poisoning","urllink":"","abstract":"","note":"","tags":"Cresols,Disinfectants,Humans,Male,Middle Aged,Renal Dialysis","weight":"10","publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"0941-0198","isi":"","key":"Evers1994","howpublished":""} , {userid:"Dr_evers", "refid":"18","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Mexiletine in terminal renal failure and various dialysis procedures","year":"1989","author":"J Evers, W Messer, F Aboudan, K Finke","journal":"Klin Wochenschr now J Mol Med","volume":"67","number":"","pages":"995-998","month":"","doi":"10.1007\/BF01716063","pubmed":"2615291","pdflink":"https:\/\/www.researchgate.net\/publication\/20541507_Mexiletin_bei_terminaler_Niereninsuffizienz_und_verschiedenen_Dialyseverfahren_Abstract_in_English","urllink":"","abstract":"We monitored the plasma levels of mexiletine in 20 dialysis patients with severe cardiac arrhythmias after repeated oral administration and the elimination by various dialysis procedures. The levels of mexiletine in plasma and dialysate were assayed by high-pressure liquid chromatography. After repeated administration of mexiletine 400-600 mg\/day trough levels were in the range from 500-2,000 ng\/ml. Treatment controlled by Holter monitoring was effective in 13\/20 patients. Doses of 600 mg\/day and more often were not tolerated by patients with dialysis after some weeks. There was no important removal of mexiletine from plasma during hemodialysis, hemofiltration, peritoneal dialysis, or plasmapheresis. In conclusion, we recommend a slightly reduced dosage of 400-600 mg mexiletine\/day (usually 600-800 mg) for patients with end-stage renal insufficiency, irrespective of dialysis.","note":"J Evers, J Brodbeck, T Hespe, E Renner (1992) Mexiletin-Clearance bei Dialysepatienten In:Klin Wochenschr 69 (Suppl XXIII) 98, 36\r\nJ Evers (1990) Antiarrhythmika bei Niereninsuffiziez In:Nieren- und Hochdruckkrankheiten 19: 486-488 Dustri Oberhaching-M\u00fcnchen ","tags":"Adult,Aged,Arrhythmias, Cardiac,Dose-Response Relationship, Drug,Female,Heart Ventricles,Hemofiltration,Humans,Kidney Failure, Chronic,Male,Metabolic Clearance Rate,Mexiletine,Middle Aged,Peritoneal Dialysis,Plasmapheresis,Renal Dialysis","weight":"18","publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"0023-2173","isi":"","key":"Evers1989","howpublished":""} , {userid:"Dr_evers", "refid":"20","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Pharmacokinetics of isosorbide-5-nitrate during haemodialysis and peritoneal dialysis.","year":"1987","author":"J Evers, R Bonn, A Boertz, W Cawello, V Luckow, M Fey, F Aboudan, H A Dickmans","journal":"Eur J Clin Pharmacol","volume":"32","number":"","pages":"503-505","month":"","doi":"10.1007\/BF00637678","pubmed":"3622599","pdflink":"https:\/\/www.researchgate.net\/publication\/19538530_Pharmacokinetics_of_isosorbide-5-nitrate_during_haemodialysis_and_peritoneal_dialysis","urllink":"","abstract":"The pharmacokinetics of isosorbide-5-nitrate (IS-5-N) was studied in ten patients on haemodialysis (HD) after a single oral dose of 20 mg IS-5-N, and in six patients on continuous ambulatory peritoneal dialysis (CAPD) after repeated oral doses of 3 X 20 mg IS-5-N. There was significant removal of IS-5-N from blood during HD; Cmax decreased by about 20%, AUC(0-8 h) by 30% and t1\/2 by about 20% from 4.3 to 3.4 h, and plasma clearance was increased by 81 ml\/min. No important loss of IS-5-N was observed in patients on CAPD.","note":"","tags":"Adult,Aged,Aged, 80 and over,Female,Half-Life,Humans,Isosorbide Dinitrate,Kinetics,Male,Metabolic Clearance Rate,Middle Aged,Peritoneal Dialysis, Continuous Ambulatory,Renal Dialysis","weight":"20","publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"0031-6970","isi":"","key":"Evers1987","howpublished":""} ] } ; ajaxResultsLoaded(_ajax_res);