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{userid:"rui.medeiros", "articletype":"article","pages":"","author":"T Hess, C Maj, J Gehlen, O Borisov, S L Haas, I Gockel, M Vieth, G Piessen, H Alakus, Y Vashist, C Pereira, M Knapp, V Schuller, A Quaas, H I Grabsch, J Trautmann, E Malecka-Wojciesko, A Mokrowiecka, J Speller, A Mayr, J Schroder, A M Hillmer, D Heider, F Lordick, A Perez-Aisa, R Campo, J Espinel, F Geijo, C Thomson, L Bujanda, F Sopena, A Lanas, M Pellise, C Pauligk, T O Goetze, C Zelck, J Reingruber, E Hassanin, P Elbe, S Alsabeah, M Lindblad, M Nilsson, N Kreuser, R Thieme, F Tavano, R Pastorino, D Arzani, R Persiani, J O Jung, H Nienhuser, K Ott, R R Schumann, O Kumpf, S Burock, V Arndt, A Jakubowska, M Lawniczak, V Moreno, V Martin, M Kogevinas, M Pollan, J Dabrowska, A Salas, O Cussenot, A Boland-Auge, D Daian, J F Deleuze, E Salvi, M Teder-Laving, G Tomasello, M Ratti, C Senti, V De Re, A Steffan, A H Holscher, K Messerle, C J Bruns, A Sivins, I Bogdanova, J Skieceviciene, J Arstikyte, M Moehler, H Lang, P P Grimminger, M Kruschewski, N Vassos, C Schildberg, P Lingohr, K Ridwelski, H Lippert, N Fricker, P Krawitz, P Hoffmann, M M Nothen, L Veits, J R Izbicki, A Mostowska, F Martinon-Torres, D Cusi, R Adolfsson,  others","year":"2023","title":"Dissecting the genetic heterogeneity of gastric cancer","month":"","journal":"EBioMedicine","publisher":"","volume":"92","number":"","note":"","tags":"","booktitle":"","editor":"","abstract":"","address":"","school":"","issn":"2352-3964 (Electronic) 2352-3964 (Linking)","doi":"10.1016\/j.ebiom.2023.104616","isi":"","pubmed":"","key":"RN3323","howpublished":"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37209533","urllink":"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37209533","refid":798,"weight":798}
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{userid:"manuel.r.teixeira", "refid":"162","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.","year":"2013","author":"Rosalind A Eeles, Ali Amin Al Olama, Sara Benlloch, Edward J Saunders, Daniel A Leongamornlert, Malgorzata Tymrakiewicz, Maya Ghoussaini, Craig Luccarini, Joe Dennis, Sarah Jugurnauth-Little, Tokhir Dadaev, David E Neal, Freddie C Hamdy, Jenny L Donovan, Ken Muir, Graham G Giles, Gianluca Severi, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Fredrick Schumacher, Brian E Henderson, Loic Le Marchand, Sara Lindstrom, Peter Kraft, David J Hunter, Susan Gapstur, Stephen J Chanock, Sonja I Berndt, Demetrius Albanes, Gerald Andriole, Johanna Schleutker, Maren Weischer, Federico Canzian, Elio Riboli, Tim J Key, Ruth C Travis, Daniele Campa, Sue A Ingles, Esther M John, Richard B Hayes, Paul D P Pharoah, Nora Pashayan, Kay-Tee Khaw, Janet L Stanford, Elaine A Ostrander, Lisa B Signorello, Stephen N Thibodeau, Dan Schaid, Christiane Maier, Walther Vogel, Adam S Kibel, Cezary Cybulski, Jan Lubinski, Lisa Cannon-Albright, Hermann Brenner, Jong Y Park, Radka Kaneva, Jyotsna Batra, Amanda B Spurdle, Judith A Clements, Manuel R Teixeira, Ed Dicks, Andrew Lee, Alison M Dunning, Caroline Baynes, Don Conroy, Melanie J Maranian, Shahana Ahmed, Koveela Govindasami, Michelle Guy, Rosemary A Wilkinson, Emma J Sawyer, Angela Morgan, David P Dearnaley, Alan Horwich, Robert A Huddart, Vincent S Khoo, Christopher C Parker, Nicholas J Van As, Christopher J Woodhouse, Alan Thompson, Tim Dudderidge, Chris Ogden, Colin S Cooper, Artitaya Lophatananon, Angela Cox, Melissa C Southey, John L Hopper, Dallas R English, Markus Aly, Jan Adolfsson, Jiangfeng Xu, Siqun L Zheng, Meredith Yeager, Rudolf Kaaks, W Ryan Diver, Mia M Gaudet, Mariana C Stern, Roman Corral, Amit D Joshi, Ahva Shahabi, Tiina Wahlfors, Teuvo L J Tammela, Anssi Auvinen, Jarmo Virtamo, Peter Klarskov, B\u00f8rge G Nordestgaard, M Andreas R\u00f8der, Sune F Nielsen, Stig E Bojesen, Afshan Siddiq, Liesel M Fitzgerald, Suzanne Kolb, Erika M Kwon, Danielle M Karyadi, William J Blot, Wei Zheng, Qiuyin Cai, Shannon K McDonnell, Antje E Rinckleb, Bettina Drake, Graham Colditz, Dominika Wokolorczyk, Robert A Stephenson, Craig Teerlink, Heiko Muller, Dietrich Rothenbacher, Thomas A Sellers, Hui-Yi Lin, Chavdar Slavov, Vanio Mitev, Felicity Lose, Srilakshmi Srinivasan, Sofia Maia, Paula Paulo, Ethan Lange, Kathleen A Cooney, Antonis C Antoniou, Daniel Vincent, Fran\u00e7ois Bacot, Daniel C Tessier, Zsofia Kote-Jarai, Douglas F Easton","journal":"Nat Genet","volume":"45","number":"4","pages":"385-91, 391e1-2","month":"Apr","doi":"10.1038\/ng.2560","pubmed":"23535732","pdflink":"","urllink":"","abstract":"Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a custom Illumina array (iCOGS) in blood DNA from 25,074 prostate cancer cases and 24,272 controls from the international PRACTICAL Consortium. Twenty-three new prostate cancer susceptibility loci were identified at genome-wide significance (P < 5 \u00d7 10(-8)). More than 70 prostate cancer susceptibility loci, explaining \u223c30% of the familial risk for this disease, have now been identified. On the basis of combined risks conferred by the new and previously known risk loci, the top 1% of the risk distribution has a 4.7-fold higher risk than the average of the population being profiled. These results will facilitate population risk stratification for clinical studies.","note":"","tags":"Case-Control Studies,Cooperative Behavior,Genetic Loci,Genetic Predisposition to Disease,Genome-Wide Association Study,Genotype,Humans,Male,Meta-Analysis as Topic,Oligonucleotide Array Sequence Analysis,Polymorphism, Single Nucleotide,Prostatic Neoplasms,Risk Factors","publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"1546-1718","isi":"","key":"Eeles2013","howpublished":""}
,

{userid:"manuel.r.teixeira", "refid":"152","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.","year":"2013","author":"Ali Amin Al Olama, Zsofia Kote-Jarai, Fredrick R Schumacher, Fredrik Wiklund, Sonja I Berndt, Sara Benlloch, Graham G Giles, Gianluca Severi, David E Neal, Freddie C Hamdy, Jenny L Donovan, David J Hunter, Brian E Henderson, Michael J Thun, Michael Gaziano, Edward L Giovannucci, Afshan Siddiq, Ruth C Travis, David G Cox, Federico Canzian, Elio Riboli, Timothy J Key, Gerald Andriole, Demetrius Albanes, Richard B Hayes, Johanna Schleutker, Anssi Auvinen, Teuvo L J Tammela, Maren Weischer, Janet L Stanford, Elaine A Ostrander, Cezary Cybulski, Jan Lubinski, Stephen N Thibodeau, Daniel J Schaid, Karina D Sorensen, Jyotsna Batra, Judith A Clements, Suzanne Chambers, Joanne Aitken, Robert A Gardiner, Christiane Maier, Walther Vogel, Thilo D\u00f6rk, Hermann Brenner, Tomonori Habuchi, Sue Ingles, Esther M John, Joanne L Dickinson, Lisa Cannon-Albright, Manuel R Teixeira, Radka Kaneva, Hong-Wei Zhang, Yong-Jie Lu, Jong Y Park, Kathleen A Cooney, Kenneth R Muir, Daniel A Leongamornlert, Edward Saunders, Malgorzata Tymrakiewicz, Nadiya Mahmud, Michelle Guy, Koveela Govindasami, Lynne T O'Brien, Rosemary A Wilkinson, Amanda L Hall, Emma J Sawyer, Tokhir Dadaev, Jonathan Morrison, David P Dearnaley, Alan Horwich, Robert A Huddart, Vincent S Khoo, Christopher C Parker, Nicholas Van As, Christopher J Woodhouse, Alan Thompson, Tim Dudderidge, Chris Ogden, Colin S Cooper, Artitaya Lophatonanon, Melissa C Southey, John L Hopper, Dallas English, Jarmo Virtamo, Loic Le Marchand, Daniele Campa, Rudolf Kaaks, Sara Lindstrom, W Ryan Diver, Susan Gapstur, Meredith Yeager, Angela Cox, Mariana C Stern, Roman Corral, Markus Aly, William Isaacs, Jan Adolfsson, Jianfeng Xu, S Lilly Zheng, Tiina Wahlfors, Kimmo Taari, Paula Kujala, Peter Klarskov, B\u00f8rge G Nordestgaard, M Andreas R\u00f8der, Ruth Frikke-Schmidt, Stig E Bojesen, Liesel M Fitzgerald, Suzanne Kolb, Erika M Kwon, Danielle M Karyadi, Torben Falck Orntoft, Michael Borre, Antje Rinckleb, Manuel Luedeke, Kathleen Herkommer, Andreas Meyer, J\u00fcrgen Serth, James R Marthick, Briony Patterson, Dominika Wokolorczyk, Amanda Spurdle, Felicity Lose, Shannon K McDonnell, Amit D Joshi, Ahva Shahabi, Pedro Pinto, Joana Santos, Ana Ray, Thomas A Sellers, Hui-Yi Lin, Robert A Stephenson, Craig Teerlink, Heiko Muller, Dietrich Rothenbacher, Norihiko Tsuchiya, Shintaro Narita, Guang-Wen Cao, Chavdar Slavov, Vanio Mitev, Stephen Chanock, Henrik Gronberg, Christopher A Haiman, Peter Kraft, Douglas F Easton, Rosalind A Eeles","journal":"Hum Mol Genet","volume":"22","number":"2","pages":"408-415","month":"Jan","doi":"10.1093\/hmg\/dds425","pubmed":"23065704","pdflink":"","urllink":"","abstract":"Genome-wide association studies (GWAS) have identified multiple common genetic variants associated with an increased risk of prostate cancer (PrCa), but these explain less than one-third of the heritability. To identify further susceptibility alleles, we conducted a meta-analysis of four GWAS including 5953 cases of aggressive PrCa and 11 463 controls (men without PrCa). We computed association tests for approximately 2.6 million SNPs and followed up the most significant SNPs by genotyping 49 121 samples in 29 studies through the international PRACTICAL and BPC3 consortia. We not only confirmed the association of a PrCa susceptibility locus, rs11672691 on chromosome 19, but also showed an association with aggressive PrCa [odds ratio = 1.12 (95% confidence interval 1.03-1.21), P = 1.4 \u00d7 10(-8)]. This report describes a genetic variant which is associated with aggressive PrCa, which is a type of PrCa associated with a poorer prognosis.","note":"","tags":"","publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"1460-2083","isi":"","key":"AminAlOlama2013","howpublished":""}
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