// +author:k aoki +author:aoki 
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{userid:"muhammad.spocter", "refid":59,"repocollections":"","attachment":"","_thumb":"","articletype":"incollection","sectionheading":"","title":"Evolutionary Medicine","year":"2020","author":"Finneran, K., Aoki, T., Barnes, M. J., & Spocter, M.A.","booktitle":"Encyclopedia of Evolutionary Psychological Science","editor":"T. K. Shackelford, & V.A. Weekes-Shackelford ","pages":"","organization":"","address":" New York, NY: ","publisher":"Springer Cham","isbn":"","doi":"https:\/\/doi.org\/10.1007\/978-3-319-16999-6_2785-1","pubmed":"","pdflink":"","urllink":"","abstract":"","note":"","tags":"","weight":59}
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{userid:"sugita", "refid":87,"attachment":"","articletype":"inproceedings","sectionheading":"","title":"Chloroplast transformation in tobacco and the moss Physcomitrella patens.","year":"2001","author":"Sugiura, C., Tsuruya, K., Aoki, S., Sugita, M.","booktitle":"PS2001 Proceedings: 12th International Congress on Photosynthesis","editor":"","pages":"CD-DOM publishing","organization":"","address":"","publisher":"CSIRO Publishing ","doi":"ISBN: 0643 06711 6","pubmed":"","pdflink":"","urllink":"","abstract":"","note":"","tags":""}
,

{userid:"sugita", "articletype":"article","pages":"302-306","author":"K Hara, M Sugita, S Aoki","year":"2001","title":"Cloning and characterization of the cDNA for a plastid sigma factor from the moss Physcomitrella patens.","month":"Jan","journal":"Biochim Biophys Acta","publisher":"","volume":"1517","number":"2","note":"","tags":"Amino Acid Sequence,Bryopsida,Cloning, Molecular,DNA, Complementary,Molecular Sequence Data,Plant Proteins,Plastids,Protein Sorting Signals,Sequence Alignment,Sigma Factor","booktitle":"","editor":"","abstract":"We isolated a cDNA PpSig1 encoding a plastid sigma factor from the moss Physcomitrella patens. The PpSIG1 protein is composed of the conserved subdomains for recognition of -10 and -35 promoter elements, core complex binding and DNA melting. Southern blot analysis showed that the moss sig1 gene is likely a member of a small gene family. Transient expression assay using green fluorescent protein demonstrated that the N-terminal region of PpSIG1 functions as a chloroplast-targeting signal peptide. These observations suggest that multiple nuclear-encoded sigma factors regulate chloroplast gene expression in P. patens.","address":"","school":"","issn":"0006-3002","doi":"","isi":"","pubmed":"11342113","key":"Hara2001","howpublished":"","urllink":"","refid":32}
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{userid:"junji_yodoi", "articletype":"article","pages":"289-292","author":"J Yodoi, K Takatsuki, N Aoki, T Masuda","year":"1974","title":"Chronic lymphocytic leukemia of T-cell origin: demonstration in two cases by the use of anti-thymocyte membrane antiserum.","month":"Jun","journal":"Nippon Ketsueki Gakkai Zasshi","publisher":"","volume":"37","number":"3","note":"","tags":"Adult,Animals,Cell Membrane,Child,Child, Preschool,Cytotoxicity Tests, Immunologic,Female,Humans,Immune Sera,Leukemia, Lymphoid,Male,Middle Aged,Rabbits,T-Lymphocytes","booktitle":"","editor":"","abstract":"","address":"","school":"","issn":"0001-5806","doi":"","isi":"","pubmed":"4548301","key":"Yodoi1974","howpublished":"","urllink":"","refid":487}
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{userid:"kaz.kitamura", "articletype":"article","pages":"566-569","author":"M Tokunaga, T Aoki, M Hiroshima, K Kitamura, T Yanagida","year":"1997","title":"Subpiconewton intermolecular force microscopy.","month":"Feb","journal":"Biochemical and biophysical research communications","publisher":"","volume":"231","number":"3","note":"","tags":"Eyeglasses,Hot Temperature,Microscopy, Atomic Force,Motion,Potassium Chloride,Proteins,Solubility,Water,Zinc Oxide","booktitle":"","editor":"","abstract":"We refined scanning probe force microscopy to improve the sensitivity of force detection and control of probe position. Force sensitivity was increased by incorporating a cantilever with very low stiffness, 0.1 pN\/ nm, which is over 1000-fold more flexible than is typically used in conventional atomic force microscopy. Thermal bending motions of the cantilever were reduced to less than 1 nm by exerting feed-back positioning with laser radiation pressure. The system was tested by measuring electrostatic repulsive forces or hydrophobic attractive forces in aqueous solutions. Subpiconewton intermolecular forces were resolved at controlled gaps in the nanometer range between the probe and a material surface. These levels of force and position sensitivity meet the requirements needed for future investigations of intermolecular forces between biological macromolecules such as proteins, lipids and DNA.","address":"","school":"","issn":"0006-291X","doi":"10.1006\/bbrc.1997.6144","isi":"","pubmed":"9070846","key":"Tokunaga1997","howpublished":"","urllink":"","refid":28,"weight":28}
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{userid:"sugita", "refid":"89","attachment":"","articletype":"article","sectionheading":"","title":"Characterization of two genes, Sig1 and Sig2, encoding distinct plastid sigma factors(1) in the moss Physcomitrella patens: phylogenetic relationships to plastid sigma factors in higher plants.","year":"2001","author":"K Hara, M Morita, R Takahashi, M Sugita, S Kato, S Aoki","journal":"FEBS Lett","volume":"499","number":"1-2","pages":"87-91","month":"Jun","doi":"","pubmed":"11418118","pdflink":"","urllink":"","abstract":"We isolated the cDNA for a sigma factor from the moss Physcomitrella patens, which possesses unusually large N-terminal extension and the conserved subdomains 1.2-4.2. Phylogenetic analyses indicated that this novel sigma factor and PpSIG1*(2), a plastid sigma factor previously identified from Physcomitrella, were classified into SigA and SigB groups, two major classes of higher plant plastid sigma factors, respectively. According to the nomenclature recently proposed, we renamed PpSIG1* into PpSIG2, and named the novel sigma factor PpSIG1. A transient expression assay using a green fluorescent protein showed that the N-terminal region of PpSIG1 acts as a chloroplast-targeting signal. Reverse transcription-PCR experiments showed that light induces the expression of the Sig1 and Sig2 genes encoding PpSIG1 and PpSIG2, respectively. Thus, PpSIG1 and PpSIG2 are likely plastid sigma factors regulating plastid gene expression in response to light signals.","note":"","tags":"Amino Acid Sequence,Arabidopsis,Arabidopsis Proteins,Bryopsida,Gene Expression Regulation, Plant,Genes, Plant,Genes, Reporter,Light,Molecular Sequence Data,Multigene Family,Phylogeny,Plant Proteins,Plastids,Protein Transport,RNA, Messenger,RNA, Plant,Recombinant Fusion Proteins,Reverse Transcriptase Polymerase Chain Reaction,Sequence Alignment,Sigma Factor"}
,

{userid:"christopher.cain", "articletype":"article","pages":"4723-4739","author":"Hermina Nedelescu, Catherine M Kelso, Gabriel L\u00e1zaro-Mu\u00f1oz, Mari Purpura, Christopher K Cain, Joseph E Ledoux, Chiye Aoki","year":"2010","title":"Endogenous GluR1-containing AMPA receptors translocate to asymmetric synapses in the lateral amygdala during the early phase of fear memory formation: an electron microscopic immunocytochemical study.","month":"Dec","journal":"J Comp Neurol","publisher":"","volume":"518","number":"23","note":"","tags":"Amygdala,Animals,Avoidance Learning,Male,Microscopy, Immunoelectron,Neuropsychological Tests,Post-Synaptic Density,Rats,Rats, Sprague-Dawley,Receptors, AMPA,Synapses,Synaptic Membranes","booktitle":"","editor":"","abstract":"Although glutamate receptor 1 (GluR1)-containing \u03b1-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors (GluR1-AMPARs) are implicated in synaptic plasticity, it has yet to be demonstrated whether endogenous GluR1-AMPARs undergo activity-dependent trafficking in vivo to synapses to support short-term memory (STM) formation. The paradigm of pavlovian fear conditioning (FC) can be used to address this question, because a discrete region-the lateral amygdala (LA)-has been shown unambiguously to be necessary for the formation of the associative memory between a neutral stimulus (tone [CS]) and a noxious stimulus (foot shock [US]). Acquisition of STM for FC can occur even in the presence of protein synthesis inhibitors, indicating that redistribution of pre-existing molecules to synaptic junctions underlies STM. We employed electron microscopic immunocytochemistry to evaluate alterations in the distribution of endogenous AMPAR subunits at LA synapses during the STM phase of FC. Rats were sacrificed 40 minutes following three CS-US pairings. In the LA of paired animals, relative to na\u00efve animals, the proportion of GluR1-AMPAR-labeled synapses increased 99% at spines and 167% in shafts. In the LA of unpaired rats, for which the CS was never associated with the US, GluR1 immunoreactivity decreased 84% at excitatory shaft synapses. GluR2\/3 immunoreactivity at excitatory synapses did not change detectably following paired or unpaired conditioning. Thus, the early phase of FC involves rapid redistribution specifically of the GluR1-AMPARs to the postsynaptic membranes in the LA, together with the rapid translocation of GluR1-AMPARs from remote sites into the spine head cytoplasm, yielding behavior changes that are specific to stimulus contingencies.","address":"","school":"","issn":"1096-9861","doi":"10.1002\/cne.22472","isi":"","pubmed":"20963825","key":"Nedelescu2010","howpublished":"","urllink":"","refid":6}
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{userid:"kato", "articletype":"article","pages":"2133-2137","author":"H Yamasue, T Fukui, R Fukuda, H Yamada, S Yamasaki, N Kuroki, O Abe, K Kasai, K Tsujii, A Iwanami, S Aoki, K Ohtomo, N Kato, T Kato","year":"2002","title":"1H-MR spectroscopy and gray matter volume of the anterior cingulate cortex in schizophrenia.","month":"Nov","journal":"Neuroreport","publisher":"","volume":"13","number":"16","note":"","tags":"Adult,Aspartic Acid,Choline,Creatine,Emotions,Female,Gyrus Cinguli,Humans,Magnetic Resonance Imaging,Magnetic Resonance Spectroscopy,Male,Middle Aged,Schizophrenia,Schizophrenic Psychology","booktitle":"","editor":"","abstract":"Schizophrenic and normal control subjects were examined using both H-magnetic resonance spectroscopy (MRS) and structural MR imaging, in order to accurately assess the partial volume within the spectroscopic volume of interest (VOI) in the anterior cingulate cortex. The gray matter volume within VOI correlated positively with the N-acetyl-aspartate (NAA) to choline (Cho) ratio in schizophrenics only, not in controls. Schizophrenic patients had a reduced NAA\/Cho ratio and an elevated Cho\/creatine ratio compared to controls after the partial volume effect was eliminated. There was a significant negative correlation between the NAA\/Cho ratio and the severity of blunted affect symptom in schizophrenics. These results provide further support to the idea that the measures of H-MRS indicate not only neuronal loss but also neuronal dysfunction in schizophrenia.","address":"","school":"","issn":"0959-4965","doi":"","isi":"","pubmed":"12438941","key":"Yamasue2002","howpublished":"","urllink":"","refid":138}
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