// +author:m ashton +author:ashton var _ajax_res = { hits: 57, first: 0, results: [ {userid:"michael-johnson", "refid":"74","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Process of care in Hispanic, black, and white VA beneficiaries.","year":"2002","author":"Howard S Gordon, Michael L Johnson, Carol M Ashton","journal":"Medical care","volume":"40","number":"9","pages":"824-833","month":"Sep","doi":"10.1097\/01.MLR.0000024721.45426.8D","pubmed":"12218772","pdflink":"","urllink":"","abstract":"To examine whether process of hospital care differs among Hispanic, black, and white VA beneficiaries.","note":"","tags":"African Americans,Analysis of Variance,Case-Control Studies,Chi-Square Distribution,Diabetes Mellitus,European Continental Ancestry Group,Heart Failure,Hispanic Americans,Hospitals, Veterans,Humans,Linear Models,Male,Process Assessment (Health Care),Pulmonary Disease, Chronic Obstructive,Quality of Health Care,United States,Veterans","weight":74,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"0025-7079","isi":"","key":"Gordon2002","howpublished":""} , {userid:"michael-johnson", "articletype":"article","pages":"415-421","author":"C M Ashton, D H Kuykendall, M L Johnson, N P Wray, L Wu","year":"1995","title":"The association between the quality of inpatient care and early readmission.","month":"Mar","journal":"Annals of internal medicine","publisher":"","volume":"122","number":"6","note":"","tags":"APACHE,Aged,Cardiac Output, Low,Case-Control Studies,Comorbidity,Diabetes Mellitus,Hospitals, Veterans,Humans,Lung Diseases, Obstructive,Male,Middle Aged,Multivariate Analysis,Outcome and Process Assessment (Health Care),Patient Discharge,Patient Readmission,United States","booktitle":"","editor":"","abstract":"To determine whether the quality of care during a hospital stay is associated with unplanned readmission within 14 days.","address":"","school":"","issn":"0003-4819","doi":"","isi":"","pubmed":"7856989","key":"Ashton1995","howpublished":"","urllink":"","refid":78,"weight":78} , {userid:"michael-johnson", "articletype":"article","pages":"589-602","author":"J M Geraci, C M Ashton, D H Kuykendall, M L Johnson, L Wu","year":"1997","title":"International Classification of Diseases, 9th Revision, Clinical Modification codes in discharge abstracts are poor measures of complication occurrence in medical inpatients.","month":"Jun","journal":"Medical care","publisher":"","volume":"35","number":"6","note":"","tags":"Abstracting and Indexing as Topic,Comorbidity,Diabetes Complications,Disease,Heart Failure,Hospitals, Veterans,Humans,Iatrogenic Disease,Lung Diseases, Obstructive,Medical Audit,Medical Records,Patient Discharge,Reproducibility of Results,Retrospective Studies,Sensitivity and Specificity,United States","booktitle":"","editor":"","abstract":"The authors tested the ability of International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) codes in discharge abstracts to identify medical inpatients who experienced an in-hospital complication, using complications identified through chart review as the gold standard.","address":"","school":"","issn":"0025-7079","doi":"","isi":"","pubmed":"9191704","key":"Geraci1997","howpublished":"","urllink":"","refid":81,"weight":81} , {userid:"michael-johnson", "articletype":"article","pages":"307-314","author":"J M Geraci, C M Ashton, D H Kuykendall, M L Johnson, L Wu","year":"1995","title":"In-hospital complications among survivors of admission for congestive heart failure, chronic obstructive pulmonary disease, or diabetes mellitus.","month":"Jun","journal":"Journal of general internal medicine","publisher":"","volume":"10","number":"6","note":"","tags":"APACHE,Adult,Aged,Aged, 80 and over,Cohort Studies,Comorbidity,Diabetes Complications,Heart Failure,Hospitalization,Hospitals, Veterans,Humans,Lung Diseases, Obstructive,Male,Middle Aged,Outcome and Process Assessment (Health Care),Retrospective Studies,United States","booktitle":"","editor":"","abstract":"To determine the frequency of hospital complications among survivors of inpatient treatment for congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), or diabetes mellitus (DM).","address":"","school":"","issn":"0884-8734","doi":"","isi":"","pubmed":"7562121","key":"Geraci1995","howpublished":"","urllink":"","refid":82,"weight":82} , {userid:"michael-johnson", "refid":"83","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Identifying complications and low provider adherence to normative practices using administrative data.","year":"1995","author":"D H Kuykendall, C M Ashton, M L Johnson, J M Geraci","journal":"Health services research","volume":"30","number":"4","pages":"531-554","month":"Oct","doi":"","pubmed":"7591780","pdflink":"","urllink":"","abstract":"This study investigated whether unexpected length of stay (LOS) could be used as an indicator to identify hospital patients who experienced complications or whose care exhibited low adherence to normative practices.","note":"","tags":"Diabetes Mellitus, Type 1,Facility Regulation and Control,Heart Failure,Hospitals, Veterans,Humans,Length of Stay,Linear Models,Lung Diseases, Obstructive,Outcome Assessment (Health Care),Quality of Health Care,United States","weight":83,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"0017-9124","isi":"","key":"Kuykendall1995","howpublished":""} , {userid:"michael-johnson", "articletype":"article","pages":"798-808","author":"C M Ashton, D H Kuykendall, M L Johnson, N P Wray","year":"1999","title":"An empirical assessment of the validity of explicit and implicit process-of-care criteria for quality assessment.","month":"Aug","journal":"Medical care","publisher":"","volume":"37","number":"8","note":"","tags":"Case-Control Studies,Diabetes Mellitus,Heart Failure,Hospitals, Veterans,Humans,Lung Diseases, Obstructive,Male,Observer Variation,Patient Readmission,Process Assessment (Health Care),Quality Indicators, Health Care,Reproducibility of Results,Statistics, Nonparametric,United States","booktitle":"","editor":"","abstract":"To evaluate the validity of three criteria-based methods of quality assessment: unit weighted explicit process-of-care criteria; differentially weighted explicit process-of-care criteria; and structured implicit process-of-care criteria.","address":"","school":"","issn":"0025-7079","doi":"","isi":"","pubmed":"10448722","key":"Ashton1999","howpublished":"","urllink":"","refid":76,"weight":76} , {userid:"michael-johnson", "articletype":"article","pages":"140-148","author":"J M Geraci, C M Ashton, D H Kuykendall, M L Johnson, J Souchek, D del Junco, N P Wray","year":"1999","title":"The association of quality of care and occurrence of in-hospital, treatment-related complications.","month":"Feb","journal":"Medical care","publisher":"","volume":"37","number":"2","note":"","tags":"APACHE,Adult,Aged,Aged, 80 and over,Cohort Studies,Diabetes Complications,Diabetes Mellitus,Female,Heart Failure,Hospitals, Veterans,Humans,Iatrogenic Disease,Incidence,Lung Diseases, Obstructive,Male,Medical History Taking,Middle Aged,Outcome and Process Assessment (Health Care),Patient Discharge,Quality of Health Care,Retrospective Studies,Risk Factors,Southwestern United States","booktitle":"","editor":"","abstract":"Little data exist supporting the association of quality of care and nonfatal adverse outcomes in hospitalized patients, yet those outcomes are routinely scrutinized in quality assessment efforts.","address":"","school":"","issn":"0025-7079","doi":"","isi":"","pubmed":"10024118","key":"Geraci1999","howpublished":"","urllink":"","refid":77,"weight":77} , {userid:"joel.tarning", "articletype":"article","pages":"3400-3410","author":"J Tarning, N Lindegardh, S Sandberg, N J P Day, N J White, M Ashton","year":"2008","title":"Pharmacokinetics and metabolism of the antimalarial piperaquine after intravenous and oral single doses to the rat.","month":"Aug","journal":"Journal of pharmaceutical sciences","publisher":"","volume":"97","number":"8","note":"","tags":"Administration, Oral,Animals,Antimalarials,Biological Availability,Half-Life,Infusions, Intravenous,Male,Quinolines,Rats,Rats, Sprague-Dawley","booktitle":"","editor":"","abstract":"This study aimed to evaluate the pharmacokinetic properties of piperaquine in the rat after intravenous and oral administration, and to identify and characterize the main piperaquine metabolites in rat plasma, urine, faeces and bile after intravenous administration. Male Sprague-Dawley rats were administered piperaquine as an emulsion orally or as a short-term intravenous infusion. Venous blood for pharmacokinetic evaluation was frequently withdrawn up to 90 h after dose. Urine, bile and faeces were collected after an infusion in rats kept in metabolic cages or in anesthetized rats. Pharmacokinetic characterization was done by compartmental modeling and non-compartmental analysis using WinNonlin. Piperaquine disposition was best described by a 3-compartment model with a rapid initial distribution phase after intravenous administration. The pharmacokinetics of piperaquine was characterized by a low clearance, a large volume of distribution and a long terminal half-life. Piperaquine displayed a low biliary clearance and less than 1% of the total dose was recovered in urine. The absolute oral bioavailability was approximately 50%. The main metabolite after intravenous administration of piperaquine was a carboxylic acid product identical to that reported in humans. The similarity with results in humans indicates the rat to be a suitable species for nonclinical in vivo piperaquine studies.","address":"","school":"","issn":"1520-6017","doi":"10.1002\/jps.21226","isi":"","pubmed":"17969131","key":"Tarning2008","howpublished":"","urllink":"","refid":"37","weight":"37"} , {userid:"rui.medeiros", "articletype":"article","pages":"","author":"D M Junqueira, R M de Medeiros, M C Matte, L A Ara\u00fajo, J A Chies, P Ashton-Prolla, S E Almeida","year":"2011","title":"Reviewing the history of HIV-1 : spread of subtype B in the Americas","month":"","journal":"","publisher":"","volume":"6","number":"11","note":"1932-6203 Junqueira, Dennis Maletich de Medeiros, R\u00fabia Mar\u00edlia Matte, Maria Cristina Cotta Ara\u00fajo, Leonardo Augusto Luvison Chies, Jose Artur Bogo Ashton-Prolla, Patricia Almeida, Sabrina Esteves de Matos Historical Article Journal Article Research Support, Non-U.S. Gov't Review PLoS One. 2011;6(11):e27489. doi: 10.1371\/journal.pone.0027489. Epub 2011 Nov 23.","tags":"Americas\/epidemiology Base Sequence Bayes Theorem HIV Infections\/classification\/*history\/*transmission\/virology HIV-1\/*genetics\/isolation & purification History, 20th Century Humans Phylogeny","booktitle":"","editor":"","abstract":"The dispersal of HIV-1 subtype B (HIV-1B) is a reflection of the movement of human populations in response to social, political, and geographical issues. The initial dissemination of HIV-1B outside Africa seems to have included the passive involvement of human populations from the Caribbean in spreading the virus to the United States. However, the exact pathways taken during the establishment of the pandemic in the Americas remain unclear. Here, we propose a geographical scenario for the dissemination of HIV-1B in the Americas, based on phylogenetic and genetic statistical analyses of 313 available sequences of the pol gene from 27 countries. Maximum likelihood and bayesian inference methods were used to explore the phylogenetic relationships between HIV-1B sequences, and molecular variance estimates were analyzed to infer the genetic structure of the viral population. We found that the initial dissemination and subsequent spread of subtype B in the Americas occurred via a single introduction event in the Caribbean around 1964 (1950-1967). Phylogenetic trees present evidence of several primary outbreaks in countries in South America, directly seeded by the Caribbean epidemic. Cuba is an exception insofar as its epidemic seems to have been introduced from South America. One clade comprising isolates from different countries emerged in the most-derived branches, reflecting the intense circulation of the virus throughout the American continents. Statistical analysis supports the genetic compartmentalization of the virus among the Americas, with a close relationship between the South American and Caribbean epidemics. These findings reflect the complex establishment of the HIV-1B pandemic and contribute to our understanding between the migration process of human populations and virus diffusion.","address":"","school":"","issn":"1932-6203","doi":"10.1371\/journal.pone.0027489","isi":"","pubmed":"","key":"ref273","howpublished":"","urllink":"","refid":642,"weight":642} , {userid:"fergal.grace", "articletype":"misc","pages":"","author":"G W Davison, R Morgan, N Hiscock, N Boisseau, J Garcia, F Grace, I S Young, B Davies, L Castell, T Ashton, D M Bailey","year":"2003","title":"ESR spectropic detection of exercise-induced free radical production : The significance of normobaric hypoxia and peripheral leucocytes","month":"","journal":"","publisher":"","volume":"","number":"","note":"","tags":"","booktitle":"","editor":"","abstract":"","address":"","school":"","issn":"","doi":"","isi":"","pubmed":"","key":"ref186","howpublished":" internal-pdf:\/\/2278141497\/ISEI_2003_abstracts.pdf","urllink":" internal-pdf:\/\/2278141497\/ISEI_2003_abstracts.pdf","refid":77,"weight":77} ] } ; ajaxResultsLoaded(_ajax_res);