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{userid:"brian.e.louie", "articletype":"article","pages":"","author":"Brian E Louie, Andreas M Schneider, Drew B Schembre, Ralph W Aye","year":"2016","title":"Impact of prior interventions on outcomes during per oral endoscopic myotomy.","month":"Aug","journal":"Surgical endoscopy","publisher":"","volume":"","number":"","note":"","tags":"","booktitle":"","editor":"","abstract":"Per oral endoscopic myotomy (POEM) is performed by accessing the submucosal space of the esophagus. This space may be impacted by prior interventions such as submucosal injections, dilations or previous myotomies. These interventions could make POEM more difficult and may deter surgeons during their initial experience. We sought to determine the impact of prior interventions on our early experience.","address":"","school":"","issn":"1432-2218","doi":"10.1007\/s00464-016-5182-5","isi":"","pubmed":"27553792","key":"Louie2016","howpublished":"","urllink":"","refid":72,"weight":72}
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{userid:"joel.tarning", "articletype":"article","pages":"","author":"Myat P Kyaw, Myat H Nyunt, Khin Chit, Moe M Aye, Kyin H Aye, Niklas Lindegardh, Joel Tarning, Mallika Imwong, Christopher G Jacob, Charlotte Rasmussen, Jamie Perin, Pascal Ringwald, Myaing M Nyunt","year":"2013","title":"Reduced susceptibility of Plasmodium falciparum to artesunate in southern Myanmar.","month":"03","journal":"PloS one","publisher":"","volume":"8","number":"3","note":"","tags":"Adult,Antimalarials,Artemisinins,Cambodia,Drug Resistance,Female,Humans,Malaria, Falciparum,Male,Myanmar,Plasmodium falciparum","booktitle":"","editor":"","abstract":"Plasmodium falciparum resistance to artemisinins, the first line treatment for malaria worldwide, has been reported in western Cambodia. Resistance is characterized by significantly delayed clearance of parasites following artemisinin treatment. Artemisinin resistance has not previously been reported in Myanmar, which has the highest falciparum malaria burden among Southeast Asian countries.","address":"","school":"","issn":"1932-6203","doi":"10.1371\/journal.pone.0057689","isi":"","pubmed":"23520478","key":"Kyaw2013","howpublished":"","urllink":"","refid":"45","weight":"45"}
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{userid:"brian.e.louie", "articletype":"article","pages":"","author":"Lisa M Brown, Brian E Louie, Nicole Jackson, Alexander S Farivar, Ralph W Aye, Eric Valli\u00e8res","year":"2016","title":"Recurrence and Survival After Segmentectomy in Patients With Prior Lung Resection for Early-Stage Non-Small Cell Lung Cancer.","month":"Jun","journal":"The Annals of thoracic surgery","publisher":"","volume":"","number":"","note":"","tags":"","booktitle":"","editor":"","abstract":"Lobectomy is the standard of care for patients with early-stage non-small cell lung cancer (NSCLC). However, the treatment of choice for patients with prior lung resection and a second primary NSCLC has not been established. We compared rates and patterns of recurrence and survival in patients with and without prior lung resection treated by segmentectomy and determined predictors of recurrence.","address":"","school":"","issn":"1552-6259","doi":"10.1016\/j.athoracsur.2016.04.037","isi":"","pubmed":"27350237","key":"Brown2016","howpublished":"","urllink":"","refid":8,"weight":8}
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{userid:"brian.e.louie", "articletype":"article","pages":"","author":"Ben M Hunt, Alexander S Farivar, Eric Valli\u00e8res, Brian E Louie, Ralph W Aye, Eva E Flores, Jed A Gorden","year":"2013","title":"Reply: To PMID 22513274.","month":"Oct","journal":"The Annals of thoracic surgery","publisher":"","volume":"96","number":"4","note":"","tags":"Catheters,Drainage,Female,Humans,Insufflation,Male,Palliative Care,Pleural Effusion, Malignant,Pleurodesis,Talc","booktitle":"","editor":"","abstract":"","address":"","school":"","issn":"1552-6259","doi":"10.1016\/j.athoracsur.2013.06.042","isi":"","pubmed":"24088484","key":"Hunt2013","howpublished":"","urllink":"","refid":40,"weight":40}
,

{userid:"brian.e.louie", "articletype":"article","pages":"","author":"Andreas M Schneider, Brian E Louie, Heather F Warren, Alexander S Farivar, Drew B Schembre, Ralph W Aye","year":"2016","title":"A Matched Comparison of Per Oral Endoscopic Myotomy to Laparoscopic Heller Myotomy in the Treatment of Achalasia.","month":"Aug","journal":"Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract","publisher":"","volume":"","number":"","note":"","tags":"","booktitle":"","editor":"","abstract":"Per oral endoscopic myotomy (POEM) is increasingly utilized to treat patients with achalasia. Early results have demonstrated significant improvement of symptoms, but there are concerns about postoperative reflux. With only limited comparative data available, we sought to compare POEM to laparoscopic Heller myotomy (LHM) with partial fundoplication.","address":"","school":"","issn":"1873-4626","doi":"10.1007\/s11605-016-3232-x","isi":"","pubmed":"27514392","key":"Schneider2016","howpublished":"","urllink":"","refid":73,"weight":73}
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{userid:"brian.e.louie", "articletype":"article","pages":"1734-1740","author":"Ben M Hunt, Brian E Louie, Drew B Schembre, Anthony G Bohorfoush, Alexander S Farivar, Ralph W Aye","year":"2013","title":"Outcomes in patients who have failed endoscopic therapy for dysplastic Barrett's metaplasia or early esophageal cancer.","month":"May","journal":"The Annals of thoracic surgery","publisher":"","volume":"95","number":"5","note":"","tags":"Aged,Barrett Esophagus,Esophageal Neoplasms,Esophagectomy,Esophagoscopy,Female,Humans,Male,Metaplasia,Neoplasm Staging,Retrospective Studies","booktitle":"","editor":"","abstract":"Endoscopic therapy (ablation \u00b1 mucosal resection) for esophageal high-grade dysplasia (HGD) or intramucosal carcinoma has demonstrated promising results. Little is known about patients who have persistent or progressive disease despite endotherapy. We compared patients who had successful eradication of their disease with those in whom endotherapy failed to try to identify factors predictive of failure and outcomes after salvage therapy.","address":"","school":"","issn":"1552-6259","doi":"10.1016\/j.athoracsur.2013.02.023","isi":"","pubmed":"23561804","key":"Hunt2013","howpublished":"","urllink":"","refid":44,"weight":44}
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{userid:"brian.e.louie", "articletype":"article","pages":"951-7; discussion 957-8","author":"Ralph W Aye, Lee L Swanstrom, Seema Kapur, Gordon Buduhan, Christy M Dunst, Ariel Knight, Judith A Malmgren, Brian E Louie","year":"2012","title":"A randomized multiinstitution comparison of the laparoscopic Nissen and Hill repairs.","month":"Sep","journal":"The Annals of thoracic surgery","publisher":"","volume":"94","number":"3","note":"","tags":"Adolescent,Adult,Aged,Body Mass Index,Endosonography,Follow-Up Studies,Fundoplication,Gastroesophageal Reflux,Humans,Laparoscopy,Male,Middle Aged,Pain Measurement,Pain, Postoperative,Patient Positioning,Postoperative Complications,Preoperative Care,Prospective Studies,Quality of Life,Risk Assessment,Severity of Illness Index,Single-Blind Method,Suture Techniques,Treatment Outcome,Young Adult","booktitle":"","editor":"","abstract":"Laparoscopic Hill repair (LHR) and laparoscopic Nissen fundoplication (LNF) are established surgical antireflux procedures but have never been compared in a prospective trial. This trial was designed to compare the effectiveness of LHR against the gold-standard LNF.","address":"","school":"","issn":"1552-6259","doi":"10.1016\/j.athoracsur.2012.04.083","isi":"","pubmed":"22818965","key":"Aye2012","howpublished":"","urllink":"","refid":49,"weight":49}
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{userid:"brian.e.louie", "articletype":"article","pages":"1053-7; discussion 1057-9","author":"Ben M Hunt, Alexander S Farivar, Eric Valli\u00e8res, Brian E Louie, Ralph W Aye, Eva E Flores, Jed A Gorden","year":"2012","title":"Thoracoscopic talc versus tunneled pleural catheters for palliation of malignant pleural effusions.","month":"Oct","journal":"The Annals of thoracic surgery","publisher":"","volume":"94","number":"4","note":"","tags":"Aged,Catheters,Drainage,Female,Follow-Up Studies,Hospital Mortality,Humans,Insufflation,Length of Stay,Male,Palliative Care,Pleural Effusion, Malignant,Pleurodesis,Retrospective Studies,Survival Rate,Talc,Thoracic Surgery, Video-Assisted,Treatment Outcome,Washington","booktitle":"","editor":"","abstract":"A malignant pleural effusion (MPE) is a late complication of malignancy that affects respiratory function and quality of life. A strategy for palliation of the symptoms caused by MPE should permanently control fluid accumulation, preclude any need for reintervention, and limit hospital length of stay (LOS). We compared video-assisted thorascopic (VATS) talc insufflation with placement of a tunneled pleural catheter (TPC) to assess which intervention better met these palliative goals.","address":"","school":"","issn":"1552-6259","doi":"10.1016\/j.athoracsur.2012.01.103","isi":"","pubmed":"22513274","key":"Hunt2012","howpublished":"","urllink":"","refid":52,"weight":52}
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{userid:"brian.e.louie", "articletype":"article","pages":"362-367","author":"B M Hunt, B E Louie, C M Dunst, J C Lipham, A S Farivar, A Sharata, R W Aye","year":"2014","title":"Esophagectomy for failed endoscopic therapy in patients with high-grade dysplasia or intramucosal carcinoma.","month":"May\/Jun","journal":"Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus \/ I.S.D.E","publisher":"","volume":"27","number":"4","note":"","tags":"Aged,Barrett Esophagus,Carcinoma,Catheter Ablation,Cohort Studies,Esophageal Neoplasms,Esophagectomy,Esophagoscopy,Female,Humans,Male,Mucous Membrane,Neoplasm Invasiveness,Neoplasms, Multiple Primary,Retrospective Studies,Salvage Therapy,Treatment Failure,Treatment Outcome","booktitle":"","editor":"","abstract":"Endoscopic therapy (ablation +\/- endoscopic resection) for high-grade dysplasia and\/or intramucosal carcinoma (IMC) of the esophagus has demonstrated promising results. However, there is a concern that a curable, local disease may progress to systemic disease with repeated endotherapy. We performed a retrospective review of patients who underwent esophagectomy after endotherapy at three tertiary care esophageal centers from 2006 to 2012. Our objective was to document the clinical and pathologic outcomes of patients who undergo esophagectomy after failed endotherapy. Fifteen patients underwent esophagectomy after a mean of 13\u2009months and 4.1 sessions of endotherapy for progression of disease (53%), failure to clear disease (33%), or recurrence (13%). Initially, all had Barrett's, 73% had \u22653-cm segments, 93% had a nodule or ulcer, and 91% had multifocal disease upon presentation. High-grade dysplasia was present at index endoscopy in 80% and IMC in 33%, and some patients had both. Final pathology at esophagectomy was T0 (13%), T1a (60%), T1b (20%), and T2 (7%). Positive lymph nodes were found in 20%: one patient was T2N1 and two were T1bN1. Patients with T1b, T2, or N1 disease had more IMC on index endoscopy (75% vs. 18%) and more endotherapy sessions (median 6.5 vs. 3). There have been no recurrences a mean of 20\u2009months after esophagectomy. Clinical outcomes were comparable to other series, but submucosal invasion (27%) and node-positive disease (20%) were encountered in some patients who initially presented with a locally curable disease and eventually required esophagectomy after failed endotherapy. An initial pathology of IMC or failure to clear disease after three treatments should raise concern for loco-regional progression and prompt earlier consideration of esophagectomy.","address":"","school":"","issn":"1442-2050","doi":"10.1111\/dote.12096","isi":"","pubmed":"23795720","key":"Hunt2014","howpublished":"","urllink":"","refid":43,"weight":43}
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{userid:"michael.urbich", "refid":"23","repocollections":"","attachment":"","_thumb":"","articletype":"misc","sectionheading":"Posters","title":"IPECAD Modeling Workshop 2023 Cross Comparison Challenge on Cost-Effectiveness Models in Alzheimer\u2019s Disease","year":"2023","author":"R Handels, W Herring, F Kamgar, S Aye, A Tate, C Green, A Gustavsson, A Wimo, B Winblad, A Sk\u00f6ldunger, L Lau Raket, C Bedrejo Stellick, J Hlavka, Y Wei, J Mar, M Soto-Gordoa, I de Kok, C Br\u00fcck, R Anderson, P Pemberton-Ross, M Urbich, E Spackman, B Tysinger, R Wittenberg, L J\u00f6nsson","howpublished":"ISPOR Europe, November 13-15","doi":"","pubmed":"","pdflink":"https:\/\/osf.io\/7xbez","urllink":"https:\/\/osf.io\/jv85a","abstract":"","note":"","tags":"","weight":23}
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