// +author:o ayadi +author:ayadi 
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{userid:"guillaume.pavlovic", "refid":"10","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"The mammalian gene function resource: the International Knockout Mouse Consortium.","year":"2012","author":"Allan Bradley, Konstantinos Anastassiadis, Abdelkader Ayadi, James F Battey, Cindy Bell, Marie-Christine Birling, Joanna Bottomley, Steve D Brown, Antje B\u00fcrger, Carol J Bult, Wendy Bushell, Francis S Collins, Christian Desaintes, Brendan Doe, Aris Economides, Janan T Eppig, Richard H Finnell, Colin Fletcher, Martin Fray, David Frendewey, Roland H Friedel, Frank G Grosveld, Jens Hansen, Yann H\u00e9rault, Geoffrey Hicks, Andreas H\u00f6rlein, Richard Houghton, Martin Hrab\u00e9 de Angelis, Danny Huylebroeck, Vivek Iyer, Pieter J de Jong, James A Kadin, Cornelia Kaloff, Karen Kennedy, Manousos Koutsourakis, K C Kent Lloyd, Susan Marschall, Jeremy Mason, Colin McKerlie, Michael P McLeod, Harald von Melchner, Mark Moore, Alejandro O Mujica, Andras Nagy, Mikhail Nefedov, Lauryl M Nutter, Guillaume Pavlovic, Jane L Peterson, Jonathan Pollock, Ramiro Ramirez-Solis, Derrick E Rancourt, Marcello Raspa, Jacques E Remacle, Martin Ringwald, Barry Rosen, Nadia Rosenthal, Janet Rossant, Patricia Ruiz Noppinger, Ed Ryder, Joel Zupicich Schick, Frank Schn\u00fctgen, Paul Schofield, Claudia Seisenberger, Mohammed Selloum, Elizabeth M Simpson, William C Skarnes, Damian Smedley, William L Stanford, A Francis Stewart, Kevin Stone, Kate Swan, Hamsa Tadepally, Lydia Teboul, Glauco P Tocchini-Valentini, David Valenzuela, Anthony P West, Ken-ichi Yamamura, Yuko Yoshinaga, Wolfgang Wurst","journal":"Mammalian genome : official journal of the International Mammalian Genome Society","volume":"23","number":"9-10","pages":"580-586","month":"Oct","doi":"10.1007\/s00335-012-9422-2","pubmed":"22968824","pdflink":"","urllink":"","abstract":"In 2007, the International Knockout Mouse Consortium (IKMC) made the ambitious promise to generate mutations in virtually every protein-coding gene of the mouse genome in a concerted worldwide action. Now, 5 years later, the IKMC members have developed high-throughput gene trapping and, in particular, gene-targeting pipelines and generated more than 17,400 mutant murine embryonic stem (ES) cell clones and more than 1,700 mutant mouse strains, most of them conditional. A common IKMC web portal (www.knockoutmouse.org) has been established, allowing easy access to this unparalleled biological resource. The IKMC materials considerably enhance functional gene annotation of the mammalian genome and will have a major impact on future biomedical research.","note":"","tags":"Animals,Internationality,Internet,Mice,Mice, Knockout","weight":10,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"1432-1777","isi":"","key":"Bradley2012","howpublished":""}
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