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{userid:"paul.w.ackermann", "refid":"90","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Motor point heatmap guide for neuromuscular electrical stimulation of the quadriceps muscle.","year":"2023","author":"J Flodin, R Juthberg, P W Ackermann","journal":"Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology","volume":"70","number":"","pages":"","month":"Apr","doi":"10.1016\/j.jelekin.2023.102771","pubmed":"37054655","pdflink":"","urllink":"","abstract":"To create an anatomical chart that indicates the probability of finding a motor point (MP) in different areas of the quadriceps muscle.","note":"","tags":"","weight":90,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"1873-5711","isi":"","key":"Flodin2023","howpublished":""}
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{userid:"paul.w.ackermann", "refid":"70","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Effects of electrode size and placement on comfort and efficiency during low-intensity neuromuscular electrical stimulation of quadriceps, hamstrings and gluteal muscles.","year":"2022","author":"J Flodin, R Juthberg, P W Ackermann","journal":"BMC sports science, medicine & rehabilitation","volume":"14","number":"1","pages":"","month":"Jan","doi":"10.1186\/s13102-022-00403-7","pubmed":"35034633","pdflink":"","urllink":"","abstract":"Neuromuscular electrical stimulation (NMES) may prevent muscle atrophy, accelerate rehabilitation and enhance blood circulation. Yet, one major drawback is that patient compliance is impeded by the discomfort experienced. It is well-known that the size and placement of electrodes affect the comfort and effect during high-intensity NMES. However, during low-intensity NMES the effects of electrode size\/placement are mostly unknown. Therefore, the purpose of this study was to investigate how electrode size and pragmatic placement affect comfort and effect of low-intensity NMES in the thigh and gluteal muscles.","note":"","tags":"","weight":70,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"2052-1847","isi":"","key":"Flodin2022","howpublished":""}
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{userid:"paul.w.ackermann", "refid":"87","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Correction to: Neuromuscular electrical stimulation in garments optimized for compliance.","year":"2023","author":"R Juthberg, J Flodin, L Guo, S Rodriguez, N K Persson, P W Ackermann","journal":"European journal of applied physiology","volume":"","number":"","pages":"","month":"May","doi":"10.1007\/s00421-023-05211-6","pubmed":"37154951","pdflink":"","urllink":"","abstract":"","note":"","tags":"","weight":87,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"1439-6327","isi":"","key":"Juthberg2023","howpublished":""}
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{userid:"rcalifano", "refid":"82","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"First-line immune checkpoint inhibitors for extensive stage small-cell lung cancer: clinical developments and future directions.","year":"2021","author":"A Ortega-Franco, C Ackermann, L Paz-Ares, R Califano","journal":"ESMO open","volume":"6","number":"1","pages":"","month":"Jan","doi":"10.1016\/j.esmoop.2020.100003","pubmed":"33450659","pdflink":"","urllink":"","abstract":"Small-cell lung cancer (SCLC) is an aggressive and rapidly growing disease with poor prognosis. Despite intense efforts to improve clinical outcomes, platinum\/etoposide chemotherapy has remained the most effective regimen for first-line extensive disease SCLC for decades. The addition of immune checkpoint inhibitors, and specifically programmed death-ligand 1 inhibitors, to standard platinum\/etoposide, significantly improves survival and represents a promising advance in this field. However, identification of a predictive biomarker to refine patient selection is an area of unmet need. Further understanding of tumour immunity and mechanism of resistance is required to design novel strategies that improve survival. In this review, we describe recent developments and future directions on first-line immune checkpoint blockade for extensive disease-SCLC.","note":"","tags":"","weight":82,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"2059-7029","isi":"","key":"Ortega-Franco2021","howpublished":""}
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{userid:"paul.w.ackermann", "refid":"88","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Effects on hemodynamic enhancement and discomfort of a new textile electrode integrated in a sock during calf neuromuscular electrical stimulation.","year":"2023","author":"C Sundstr\u00f6m, R Juthberg, J Flodin, L Guo, N-K Persson, P W Ackermann","journal":"European journal of applied physiology","volume":"","number":"","pages":"","month":"May","doi":"10.1007\/5584_2016_128","pubmed":"37145130","pdflink":"","urllink":"","abstract":"To compare fixed transverse textile electrodes (TTE) knitted into a sock versus motor point placed standard gel electrodes (MPE) on peak venous velocity (PVV) and discomfort, during calf neuromuscular electrical stimulation (calf-NMES).","note":"","tags":"","weight":88,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"1439-6327","isi":"","key":"Sundstr\u00f6m2023","howpublished":""}
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{userid:"paul.w.ackermann", "refid":"91","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Neuromuscular electrical stimulation in garments optimized for compliance.","year":"2023","author":"R Juthberg, J Flodin, L Guo, S Rodriguez, N K Persson, P W Ackermann","journal":"European journal of applied physiology","volume":"","number":"","pages":"","month":"Apr","doi":"10.1016\/j.exger.2017.03.006","pubmed":"37010623","pdflink":"","urllink":"","abstract":"Physical inactivity is associated with muscle atrophy and venous thromboembolism, which may be prevented by neuromuscular electrical stimulation (NMES). This study aimed to investigate the effect on discomfort, current amplitude and energy consumption when varying the frequency and phase duration of low-intensity NMES (LI-NMES) via a sock with knitting-integrated transverse textile electrodes (TTE).","note":"","tags":"","weight":91,"publisher":"","booktitle":"","editor":"","address":"","school":"","issn":"1439-6327","isi":"","key":"Juthberg2023","howpublished":""}
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{userid:"k.m.rosler", "articletype":"article","pages":"664-670","author":"T Roth, R Ackermann, R Stein, R Inderbitzi, K R\u00f6sler, R A Schmid","year":"2002","title":"Thirteen years follow-up after radical transsternal thymectomy for myasthenia gravis. Do short-term results predict long-term outcome?","month":"Apr","journal":"European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery","publisher":"","volume":"21","number":"4","note":"","tags":"Adolescent,Adult,Age Factors,Aged,Antibodies,Female,Follow-Up Studies,Humans,Male,Middle Aged,Morbidity,Myasthenia Gravis,Postoperative Complications,Predictive Value of Tests,Quality of Life,Receptors, Cholinergic,Severity of Illness Index,Sex Factors,Sternum,Switzerland,Thymectomy,Thymus Gland,Time,Time Factors,Treatment Outcome","booktitle":"","editor":"","abstract":"Long-term evaluation of efficacy and quality of life after radical surgical approach for myasthenia gravis (MG). Comparison between short-term follow-up and long-term outcome.","address":"","school":"","issn":"1010-7940","doi":"","isi":"","pubmed":"11932165","key":"Roth2002","howpublished":"","urllink":"","refid":84,"weight":84}
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{userid:"sven.haller", "articletype":"article","pages":"1335-1342","author":"S Haller, M-L Montandon, C Rodriguez, M Ackermann, F R Herrmann, P Giannakopoulos","year":"2017","title":"* Is Associated with Gray Matter Loss in the Posterior Cingulate Cortex in Healthy Elderly Controls Subsequently Developing Subtle Cognitive Decline.","month":"Jul","journal":"AJNR. American journal of neuroradiology","publisher":"","volume":"38","number":"7","note":"","tags":"Aged,Aging,Apolipoprotein E4,Cognition Disorders,Cognitive Dysfunction,Female,Follow-Up Studies,Gray Matter,Gyrus Cinguli,Healthy Volunteers,Humans,Magnetic Resonance Imaging,Male,Neuropsychological Tests,Prospective Studies","booktitle":"","editor":"","abstract":"The presence of  (*) is the strongest currently known genetic risk factor for Alzheimer disease and is associated with brain gray matter loss, notably in areas involved in Alzheimer disease pathology. Our objective was to assess the effect of * on brain structures in healthy elderly controls who subsequently developed subtle cognitive decline.","address":"","school":"","issn":"1936-959X","doi":"10.3174\/ajnr.A5184","isi":"","pubmed":"28495939","key":"Haller2017","howpublished":"","urllink":"","refid":128,"weight":128}
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{userid:"rolf.kummerli", "refid":"35","repocollections":"","attachment":"","_thumb":"","articletype":"article","sectionheading":"","title":"Habitat structure and the evolution of diffusible siderophores in bacteria","year":"2014","author":"R K\u00fcmmerli, K T Schiessl, T Waldvogel, K. McNeill, M. Ackermann","journal":"Ecology Letters","volume":"17","number":"","pages":"1536-1544","month":"","doi":"10.1111\/ele.12371","pubmed":"","pdflink":"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ele.12371\/abstract","urllink":"","abstract":"Bacteria typically rely on secreted metabolites, potentially shareable at the community level, to scavenge resources from the environment. The evolution of diffusible, shareable metabolites is, however, difficult to explain because molecules can get lost, or be exploited by cheating mutants. A key question is whether natural selection can act on molecule structure to control loss and shareability. We tested this possibility by collating information on diffusivity properties of 189 secreted iron-scavenging siderophores and the natural habitats occupied by the siderophore-producing species. In line with evolutionary theory, we found that highly diffusible siderophores have preferentially evolved in species living in structured habitats, such as soil and hosts, because structuring can keep producers and their shareable goods together. Poorly diffusible siderophores, meanwhile, have preferentially evolved in species living in unstructured habitats, such as seawater, indicating that these metabolites are less shareable and more likely provide direct benefits to the producers.","note":"","tags":"Comparative analysis, diffusion, dispersal, microbes, public goods, secondary metabolites, spatial structure, siderophores, bacteria","weight":35}
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{userid:"paul.w.ackermann", "articletype":"article","pages":"208-215","author":"N Schizas, \u00d8 Lian, F Frihagen, L Engebretsen, R Bahr, P W Ackermann","year":"2010","title":"Coexistence of up-regulated NMDA receptor 1 and glutamate on nerves, vessels and transformed tenocytes in tendinopathy.","month":"Apr","journal":"Scand J Med Sci Sports","publisher":"","volume":"20","number":"2","note":"","tags":"Adult,Biopsy,Blood Vessels,Carrier Proteins,Case-Control Studies,Female,Glutamates,Humans,Immunohistochemistry,Male,Middle Aged,Nerve Fibers,Nerve Tissue Proteins,Pain,Patellar Ligament,Receptors, N-Methyl-D-Aspartate,Tendinopathy,Up-Regulation,Young Adult","booktitle":"","editor":"","abstract":"Elevated levels of the neurotransmitter glutamate and the presence of its receptor, N-methyl-d-aspartate receptor type 1 (NMDAR1), have been established in patients with tendinopathy, i.e. chronic tendon pain and degeneration. However, whether NMDAR1 is up- or down-regulated in tendinopathy and co-localized with glutamate is still unexplored. We hypothesize that an alteration in tissue expression and in the coexistence of NMDAR1 and glutamate occurs in tendinopathy and might play a role in nociception and possibly also progression of tendon degeneration (tendinosis). We therefore examined the tissue distribution and levels of NMDAR1 and glutamate in biopsies from patients with patellar tendinopathy (n=10) and from controls (n=8). The biopsies were single- and double-stained immunohistochemically for glutamate and NMDAR1 and assessed subjectively and semi-quantitatively. The chronic painful tendons exhibited a significant elevation of NMDAR1 (ninefold), which was independent of the observed increase in glutamate (10-fold). This up-regulation of NMDAR1 and glutamate was found to be co-localized on nerve fibers as well as on morphologically altered tenocytes and blood vessels. None of the controls exhibited neuronal coexistence of glutamate and NMDAR1. The neuronal coexistence of glutamate and NMDAR1, observed in painful tendinosis but not in controls, suggests a regulatory role in intensified pain signalling.","address":"","school":"","issn":"1600-0838","doi":"10.1111\/j.1600-0838.2009.00913.x","isi":"","pubmed":"19422642","key":"Schizas2010","howpublished":"","urllink":"","refid":"21"}
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