Department of Pharmacy - Drug Sciences
University of Bari "A. Moro"
Via E. Orabona 4
70125 Bari - Italy
 | renzo.luisi@uniba.it |
EDUCATION:
1997-2000 – PhD student in Chemical Sciences at the University of Bari “A. Moro” (Mentor: Prof. S. Florio);
1996 – Degree (cum laude) in Chemistry and Pharmaceutical Technology at the University of Bari “A. Moro” (Mentor: Prof. S. Florio);
PROFESSIONAL EXPERIENCE:
2014 - Abilitation as Full Professor of Organic Chemistry
2005-present – Associate Professor of Organic Chemistry at the University of Bari “A. Moro”.
2012 – Visiting Professor at the University of Manchester – England (host professor, Jonathan Clayden).
2012 – Visiting Professor, at Brown University – USA (host professor, Paul Williard).
2011 – Visiting Professor at the University of Charlotte – USA (host professor, Craig Ogle).
2001-2005 – Assistant Professor of Organic Chemistry at the University of Bari “A. Moro”.
2000 – Research fellow at the University of Bari with consortium CINMPIS.
1998-1999 – Visiting Scholar at the Roger Adams Lab (School of Chemical Sciences) University of Illinois at Urbana – Champaign (Advisor Prof. P. Beak).
1996-1997 – Instructor Officer at the National School of Artillery in Bracciano (Rome).
1990-1994 – Employed as analytical chemist in wine quality assurance.
RECENT COLLABORATIONS:
Prof. Jonathan Clayden (University of Manchester, England); Prof. J.-ichi Yoshida, Dr Aiichiro Nagaki (Kyoto University, Japan); Prof. Paul Williard (Brown University, RI - USA); Prof. Craig Ogle (University of Charlotte, NC - USA); Prof. Larry Pratt (Medgar Evers College, the City University of New York, USA) Dr. Daniele Castagnolo (University of Newcastle, England); Prof. Ugo Azzena, Dr. Luisa Pisano (University of Sassari, Italy); Dr. Giuseppe Romanazzi (Dicatech – Polytechnic of Bari, Italy); Dr. A. Altomare, Dr. C. Cuocci, Dr. A. Moliterni, Dr. R. Rizzi (Institute of Crystallography, IC-CNR, Bari, Italy).
TEACHING:
- Physical Methods in Organic Chemistry (5-yr degree course in Chemistry and Pharmaceutical Technology);
- Organic Chemistry II (5-yr degree course in Chemistry and Pharmaceutical Technology);
- Organic Chemistry I (5-yr degree course in Chemistry and Pharmaceutical Technology);
- Monographic courses on "Modern NMR techniques for structural analysis" for PhD students in “Chemical and Molecular Sciences” and “Pharmaceutical Sciences”.
RESEARCH INTERESTS:
As an organic chemist I’m involved in the development of new sustainable synthetic methodologies for the construction of new molecules with defined stereochemistry and functional properties.
Jointly with my coworkers we are involved in three main research themes:
1) Heterosubstituted Organolithiums. We explore the reactivity of lithiated 3,4,5,6-membered N,S,O-heterocycles (aziridines, azetidines, oxazetidines, thietanes, oxazolines, piperazines. morfolines) and their utility in stereoselective synthesis. Our approach is aimed to establish the chemical and configurational stability of the lithiated intermediates as well as their structure in solution by means of modern spectrometric and spectroscopic techniques such as in line -IR, in line-MS, and NMR.
2) Microreactor Technology and Flow-Chemistry. With the aim to develop more sustainable synthetic processes, we set up a well equipped “microfluidic-lab”, at the Depatment of Pharmacy, for the development of continuous-flow microreactor-mediated organometallic and organocatalytic synthesis.
3) Molecular Dynamics. As a “curiosity driven” research activity, we investigate the dynamic behavior of small molecules that could function as molecular switches with “on-off” states and as versatile scaffolds useful in catalysis and in “dynamic-controlled and predictable reactivity”.
MEMBERSHIPS:
- Italian Chemical Society (since 1996);
- The Royal Society of Chemistry (since 2011)
- Member of ResearchGate® and LinkedIn® communities.
OTHER INFORMATION:
- Co-Editor of "Lithium Compounds in Organic Synthesis – From Fundamentals to Applications"; Publisher: Wiley-VCH Verlag GmbH & Co. KGaA, Germany.
- Department Service: Safety Committee (since 2007).
- Department Service: Member of the Advisory body (since 2007).
- Board of the Master course “REACH Regulation and CLP” activated by the University of Bari “A. Moro” (since 2011).
- Board of the Doctorate School in “Chemical and Molecular Sciences”.
- Founder and board of directors of the academic spin-off "SYNCHIMIA Materials & Nanomaterials" of the University of Bari active in the preparation of innovative material and nanomaterial useful for photonics and electronics, (chiral nonracemic products of pharmaceutical, biological and agrochemical interest, heterocyclic compounds and pheromones traps.
- Proposal reviewer for MIUR-Italian Ministry of University and Research.
- Reviewer for many international scientific journals (The Journal of Organic Chemistry, Organic Letters, The Journal of American of Chemical Society, European Journal of Organic Chemistry, ChemSusChem, Angew. Chem. Int. Ed, Synlett, Chemical Communication, Organic Biomolecular Chemistry, Tetrahedron, Tetrahedron Letters.
- Editorial Board’s of the open access journal ISRN – Organic Chemistry (Hindawi Publishing Corporation).
1997-2000 – PhD student in Chemical Sciences at the University of Bari “A. Moro” (Mentor: Prof. S. Florio);
1996 – Degree (cum laude) in Chemistry and Pharmaceutical Technology at the University of Bari “A. Moro” (Mentor: Prof. S. Florio);
PROFESSIONAL EXPERIENCE:
2014 - Abilitation as Full Professor of Organic Chemistry
2005-present – Associate Professor of Organic Chemistry at the University of Bari “A. Moro”.
2012 – Visiting Professor at the University of Manchester – England (host professor, Jonathan Clayden).
2012 – Visiting Professor, at Brown University – USA (host professor, Paul Williard).
2011 – Visiting Professor at the University of Charlotte – USA (host professor, Craig Ogle).
2001-2005 – Assistant Professor of Organic Chemistry at the University of Bari “A. Moro”.
2000 – Research fellow at the University of Bari with consortium CINMPIS.
1998-1999 – Visiting Scholar at the Roger Adams Lab (School of Chemical Sciences) University of Illinois at Urbana – Champaign (Advisor Prof. P. Beak).
1996-1997 – Instructor Officer at the National School of Artillery in Bracciano (Rome).
1990-1994 – Employed as analytical chemist in wine quality assurance.
RECENT COLLABORATIONS:
Prof. Jonathan Clayden (University of Manchester, England); Prof. J.-ichi Yoshida, Dr Aiichiro Nagaki (Kyoto University, Japan); Prof. Paul Williard (Brown University, RI - USA); Prof. Craig Ogle (University of Charlotte, NC - USA); Prof. Larry Pratt (Medgar Evers College, the City University of New York, USA) Dr. Daniele Castagnolo (University of Newcastle, England); Prof. Ugo Azzena, Dr. Luisa Pisano (University of Sassari, Italy); Dr. Giuseppe Romanazzi (Dicatech – Polytechnic of Bari, Italy); Dr. A. Altomare, Dr. C. Cuocci, Dr. A. Moliterni, Dr. R. Rizzi (Institute of Crystallography, IC-CNR, Bari, Italy).
TEACHING:
- Physical Methods in Organic Chemistry (5-yr degree course in Chemistry and Pharmaceutical Technology);
- Organic Chemistry II (5-yr degree course in Chemistry and Pharmaceutical Technology);
- Organic Chemistry I (5-yr degree course in Chemistry and Pharmaceutical Technology);
- Monographic courses on "Modern NMR techniques for structural analysis" for PhD students in “Chemical and Molecular Sciences” and “Pharmaceutical Sciences”.
RESEARCH INTERESTS:
As an organic chemist I’m involved in the development of new sustainable synthetic methodologies for the construction of new molecules with defined stereochemistry and functional properties.
Jointly with my coworkers we are involved in three main research themes:
1) Heterosubstituted Organolithiums. We explore the reactivity of lithiated 3,4,5,6-membered N,S,O-heterocycles (aziridines, azetidines, oxazetidines, thietanes, oxazolines, piperazines. morfolines) and their utility in stereoselective synthesis. Our approach is aimed to establish the chemical and configurational stability of the lithiated intermediates as well as their structure in solution by means of modern spectrometric and spectroscopic techniques such as in line -IR, in line-MS, and NMR.
2) Microreactor Technology and Flow-Chemistry. With the aim to develop more sustainable synthetic processes, we set up a well equipped “microfluidic-lab”, at the Depatment of Pharmacy, for the development of continuous-flow microreactor-mediated organometallic and organocatalytic synthesis.
3) Molecular Dynamics. As a “curiosity driven” research activity, we investigate the dynamic behavior of small molecules that could function as molecular switches with “on-off” states and as versatile scaffolds useful in catalysis and in “dynamic-controlled and predictable reactivity”.
MEMBERSHIPS:
- Italian Chemical Society (since 1996);
- The Royal Society of Chemistry (since 2011)
- Member of ResearchGate® and LinkedIn® communities.
OTHER INFORMATION:
- Co-Editor of "Lithium Compounds in Organic Synthesis – From Fundamentals to Applications"; Publisher: Wiley-VCH Verlag GmbH & Co. KGaA, Germany.
- Department Service: Safety Committee (since 2007).
- Department Service: Member of the Advisory body (since 2007).
- Board of the Master course “REACH Regulation and CLP” activated by the University of Bari “A. Moro” (since 2011).
- Board of the Doctorate School in “Chemical and Molecular Sciences”.
- Founder and board of directors of the academic spin-off "SYNCHIMIA Materials & Nanomaterials" of the University of Bari active in the preparation of innovative material and nanomaterial useful for photonics and electronics, (chiral nonracemic products of pharmaceutical, biological and agrochemical interest, heterocyclic compounds and pheromones traps.
- Proposal reviewer for MIUR-Italian Ministry of University and Research.
- Reviewer for many international scientific journals (The Journal of Organic Chemistry, Organic Letters, The Journal of American of Chemical Society, European Journal of Organic Chemistry, ChemSusChem, Angew. Chem. Int. Ed, Synlett, Chemical Communication, Organic Biomolecular Chemistry, Tetrahedron, Tetrahedron Letters.
- Editorial Board’s of the open access journal ISRN – Organic Chemistry (Hindawi Publishing Corporation).
