Prof. Vito Capriati
Università di Bari "Aldo Moro"
Dipartimento di Farmacia – Scienze del farmaco
Consorzio Interuniversitario Nazionale Metodologie e Processi Innovativi di Sintesi C.I.N.M.P.I.S.
Via E. Orabona 4
I-70125, Bari, Italy
Phone (+39) 080 5442174
Fax (+39) 080 5442539
skype: vcapriati
 | vito.capriati@uniba.it |
EDUCATION:
1990 – M.Sc. honours degree, University of Bari “Aldo Moro” (Chemistry and Pharmaceutical Technology, 5-year degree course; Mentor: Prof. Leonardo Di Nunno)
1991 – Qualified to practice as a Pharmacist with full marks (250/250)
1992-1993 – CNR (National Research Council) fellowship within "MISO" (Innovative Methodologies in Organic Synthesis) centre, then merged into “ICCOM” (Institute of Chemistry of Organometallic Compounds), Bari; Mentor: Prof. Francesco Naso
PROFESSIONAL HISTORY AND EXPERIENCE:
1990-1991 – Forensic chemist officer at the Carabinieri’s RIS (Scientific Investigation Department) of Rome
1993 – Assistant Professor of Organic Chemistry, Dipartimento di Farmacia–Scienze del Farmaco, University of Bari “Aldo Moro”
2001 – Visiting Scientist at the Department of Chemistry (Prof. Gideon Fraenkel’s group), Ohio State University (Ohio, USA)
2002-Present – Associate Professor of Organic Chemistry, Dipartimento di Farmacia–Scienze del Farmaco, University of Bari “Aldo Moro”
2003 – Visiting Professor at the Department of Chemistry (Prof. Per Ahlberg’s group), Göthenburg University (Göteborg, Sweden)
2014 – National Habilitation for Full Professorship of Organic Chemistry
PRESENT INTERNATIONAL COLLABORATIONS:
Prof. Dr. Konstantin Karaghiosoff (Ludwig-Maximilians-Universität München, Germany); Prof. Dr. Dietmar Stalke (University of Göttingen, Germany); Prof. Dr. Paul Knochel (Ludwig-Maximilians-Universität München, Germany); Dr. Sten O. Nilsson Lill (AstraZeneca, Göthenburg, Sweden); Prof. Mohamed Amedjkouh (Kjemisk institutt, Oslo, Norwey); Prof. Jacques Maddaluno, Prof. Anne Harrison-Marchand, and Prof. Hassan Oulyadi (University of Rouen, France); Prof. Eva Hevia (University of Strathclyde, UK); Dr. Joaquin Garcia-Alvarez (Universidad de Oviedo, Spain); Prof. Darren Dixon (University of Oxford, UK)
TEACHING:
• Organic Chemistry I (Master degreee course in Chemistry and Pharmaceutical Technology (5-yr degree course)) (since 2011)
• Organic Chemistry II (Master degreee course in Chemistry and Pharmaceutical Technology (5-yr degree course)) (since 2012)
• Organic Chemistry (Master degreee course in Pharmacy (5-yr degree course)) (2003–2011)
• Chemistry of Organic Natural Products (Master degree courses in Pharmacy and Chemistry and Pharmaceutical Technology (both 5-yr degree courses) (since 1997)
CONFERENCE ORGANIZATION:
• 1996 – “XXIII Convegno Nazionale della Divisione di Chimica Organica”, Monopoli (BA) (Organizing Committee)
• 2002 – “2nd Trans-Mediterranean Colloquium on Heterocyclic Chemistry” (TRAMEC), Bari (Organizing Committee)
• 2002 – Scientific meeting organized by the “Puglia Section” of the Italian Chemical Society: “I Giovani e la Ricerca Chimica in Puglia”, Bari (Organizing Committee)
• 2004 – Scientific meeting organized by the “Puglia Section” of the Italian Chemical Society: “La Chimica per la Qualità della Vita”, Bari (Organizing Committee)
• 2006 – “2nd Symposium on Heterocyclic Chemistry”, Bari (Organizing Committee)
• 2010 – One-Day Symposium on “Advances in Organolithium Chemistry” on the occasion of the 70th birthday of Prof. Saverio Florio, Dipartimento di Farmacia – Scienze del Farmaco, University of Bari (10 international speakers invited) (Co-chair)
• 2016 – “Scientific Seminars of CINMPIS Fellows (XVI Edition)”, University of Calabria, Rende (CS, Italy) (Scientific Committe)
• 2020 – “International Conference on Coordination Chemistry – ICCC (44° Edition)”, “Session Chair” within the Topic “T05 - Main Group Chemistry and Coordination Compounds“ (Organizing Committe)
ACHIEVEMENTS and HONOURS:
• 1999 – JSP Fellowship of the 34th Euchem Conference on Stereochemistry – Bürgenstock Conference (Bürgenstock, Lucerna, Switzerland)
• 1993-1995 and 1995-1997 – Nato Research Grant for the development of bilateral scientific collaborations between Italy and USA in collaboration with Prof. Saverio Florio (University of Bari, Italy) and Prof. Theodore Cohen (University of Pittsburgh, USA)
• 2009 – Recipient of the C.I.N.M.P.I.S. Prize “Innovation in Organic synthesis” awarded by the Interuniversities Consortium C.I.N.M.P.I.S.
• 2014 – Recipient of the Award of the Italian Chemical Society (Organic Division) for “Mechanistic and Theoretical Aspects of Organic Chemistry”
RESEARCH INTERESTS:
Current research interests revolve around:
• Functionalized Organolithiums and Lithium Carbenoids Chemistry: elucidation of the structure-reactivity relationship and of their dynamic behavior by means of a synergistic combination of ab initio calculations, X-ray analysis, and multinuclear magnetic resonance investigations; mechanistic and kinetics studies of enantiomerization of chiral organolithiums; synthesis of enantiomerically or diastereomerically enriched organolithiums and their stereospecific functionalization by interception with electrophiles; optimization of organometallic reactions by in-situ IR and NMR monitoring of the reactive intermediates involved; asymmetric synthesis of (new) heterocycles, natural product analogues, and “target molecules” of pharmaceutical and biological interest; the discovery of new reactions
• Organoboron and organofluorine chemistry
• Cross-coupling reactions
• Strained cycles in organic synthesis
• Preparation of key optically active “buiding blocks” as starting materials for asymmetric synthesis by means of biocatalytic processes employing enzymes or whole cells microorganisms (in collaboration with Dr. Paola Vitale)
• The development of new sustainable chemical processes using unconventional solvents (e.g., water and deep eutectic solvents)
• The development of new drugs for rare diseases
• Application of lithium chemistry in medicine and in the field of material sciences
MEMBERSHIPS:
• Italian Chemical Society (since 1992)
• The American Chemical Society (since1998)
• Interdivisional Group of "Organometallic Chemistry" of the Italian Chemical Society (since 1992)
• Interdivisional Group of "Green Chemistry" of the Italian Chemical Society (since 2014)
• Division of Chemical Education of the Italian Chemical Society (since 1992)
• International Society of Heterocyclic Chemistry (2003–2008; 2016)
MENTORING:
More than 50 undergraduates in “Pharmacy” and “Chemistry and Pharmaceutical Technology” (University of Bari, Italy); 1 Adjunct Assistant Professor (RTDa); 11 PhDs in “Chemical and Molecular Sciences”; 4 Postdocs/Fellows; 20 Erasmus students; 4 Visiting students.
PUBLICATIONS:
• Author/co-author of more than 115 papers in high-profile peer-reviewed international scientific journals (average IF 2010-2015: 5.4), including 8 Reviews; 6 editor-reviewed book chapters; 2 editor-reviewed specialized monographies; delivered more than 130 Communications (oral and poster) at national and international meetings (20 plenary and invited talks and seminars); H index: 28 (source: Scopus; 2040 citations)
• Co-Editor of "Lithium Compounds in Organic Synthesis From Fundamentals to Applications"; Publisher: Wiley-VCH Verlag GmbH & Co. KGaA, Boschst.12, 69469 Weinheim, Germany
• Co-author in the english-to-italian translation of two university textbooks of Organic Chemistry
OTHER INFORMATION:
• Application reviewer for MIUR-Italian Ministry of University and Research and peer-reviewer for many international scientific journals of Nature, American Chemical Society, Wiley-WCH, Thieme, The Royal Society of Chemistry, Bentham and Elsevier
• Collaboration with the pharmaceutical industry Dompè (L’Aquila, Italy) for the development of new drugs for rare diseases (Project PON PON01_00862; proponent: Consortium CINMPIS)
• PhD External Examiner: University of Florence (I), Department of Chemistry (Italy-France co-tutorship PhD programme, 2010), University of Camerino (I), Department of Chemistry (2014), University of Oslo, Department of Chemistry (Norway) (2016), University of Calabria (I), Department of Chemistry and Chemical Technologies (2016), University of Alicante, Department of Organic Chemistry (Spain) (2017).
• Board of Directors’ member of the Doctorate School in “Chemical and Molecular Sciences”
• Departmental coordinator of three Erasmus programme between the Department of Pharmacy–Drug Sciences and (i) the Ludwig-Maximilians-Universität München (Germany), (ii) the Oslo University (Oslo, Norway), (III) the University of Rouen (Rouen, France)
• Founding and board of directors’ member of the academic spin-off "SYNCHIMIA Materials & Nanomaterials" (LINK) at the University of Bari for the preparation of (a) innovative material and nanomaterial useful for fotonics and electronics, (b) chiral nonracemic products of pharmaceutical, biological and agrochemical interest, (c) heterocyclic compounds, (d) pheromones traps
• Legally authorized representative on behalf of the University of Bari within the Consortium C.I.N.M.P.I.S (since 2012)
• Director of Consortium C.I.N.M.P.I.S (since 2016)
• Responsible for the management of the CINMPIS project “Synthesis of New Molecules as Drugs for Rare Diseases” funded by MIUR (code: COCM8470P0) (2017)
• Volunteer Translator for EURORDIS (The European Organization for Rare Desease) whose purpose is to empower rare disease organizations, patients and families throughout Europe so as to contribute in building a rare disease community across national and linguistic lines
• Hobbies: trekking, golf, shooting, collecting stamps, and playing chess
1990 – M.Sc. honours degree, University of Bari “Aldo Moro” (Chemistry and Pharmaceutical Technology, 5-year degree course; Mentor: Prof. Leonardo Di Nunno)
1991 – Qualified to practice as a Pharmacist with full marks (250/250)
1992-1993 – CNR (National Research Council) fellowship within "MISO" (Innovative Methodologies in Organic Synthesis) centre, then merged into “ICCOM” (Institute of Chemistry of Organometallic Compounds), Bari; Mentor: Prof. Francesco Naso
PROFESSIONAL HISTORY AND EXPERIENCE:
1990-1991 – Forensic chemist officer at the Carabinieri’s RIS (Scientific Investigation Department) of Rome
1993 – Assistant Professor of Organic Chemistry, Dipartimento di Farmacia–Scienze del Farmaco, University of Bari “Aldo Moro”
2001 – Visiting Scientist at the Department of Chemistry (Prof. Gideon Fraenkel’s group), Ohio State University (Ohio, USA)
2002-Present – Associate Professor of Organic Chemistry, Dipartimento di Farmacia–Scienze del Farmaco, University of Bari “Aldo Moro”
2003 – Visiting Professor at the Department of Chemistry (Prof. Per Ahlberg’s group), Göthenburg University (Göteborg, Sweden)
2014 – National Habilitation for Full Professorship of Organic Chemistry
PRESENT INTERNATIONAL COLLABORATIONS:
Prof. Dr. Konstantin Karaghiosoff (Ludwig-Maximilians-Universität München, Germany); Prof. Dr. Dietmar Stalke (University of Göttingen, Germany); Prof. Dr. Paul Knochel (Ludwig-Maximilians-Universität München, Germany); Dr. Sten O. Nilsson Lill (AstraZeneca, Göthenburg, Sweden); Prof. Mohamed Amedjkouh (Kjemisk institutt, Oslo, Norwey); Prof. Jacques Maddaluno, Prof. Anne Harrison-Marchand, and Prof. Hassan Oulyadi (University of Rouen, France); Prof. Eva Hevia (University of Strathclyde, UK); Dr. Joaquin Garcia-Alvarez (Universidad de Oviedo, Spain); Prof. Darren Dixon (University of Oxford, UK)
TEACHING:
• Organic Chemistry I (Master degreee course in Chemistry and Pharmaceutical Technology (5-yr degree course)) (since 2011)
• Organic Chemistry II (Master degreee course in Chemistry and Pharmaceutical Technology (5-yr degree course)) (since 2012)
• Organic Chemistry (Master degreee course in Pharmacy (5-yr degree course)) (2003–2011)
• Chemistry of Organic Natural Products (Master degree courses in Pharmacy and Chemistry and Pharmaceutical Technology (both 5-yr degree courses) (since 1997)
CONFERENCE ORGANIZATION:
• 1996 – “XXIII Convegno Nazionale della Divisione di Chimica Organica”, Monopoli (BA) (Organizing Committee)
• 2002 – “2nd Trans-Mediterranean Colloquium on Heterocyclic Chemistry” (TRAMEC), Bari (Organizing Committee)
• 2002 – Scientific meeting organized by the “Puglia Section” of the Italian Chemical Society: “I Giovani e la Ricerca Chimica in Puglia”, Bari (Organizing Committee)
• 2004 – Scientific meeting organized by the “Puglia Section” of the Italian Chemical Society: “La Chimica per la Qualità della Vita”, Bari (Organizing Committee)
• 2006 – “2nd Symposium on Heterocyclic Chemistry”, Bari (Organizing Committee)
• 2010 – One-Day Symposium on “Advances in Organolithium Chemistry” on the occasion of the 70th birthday of Prof. Saverio Florio, Dipartimento di Farmacia – Scienze del Farmaco, University of Bari (10 international speakers invited) (Co-chair)
• 2016 – “Scientific Seminars of CINMPIS Fellows (XVI Edition)”, University of Calabria, Rende (CS, Italy) (Scientific Committe)
• 2020 – “International Conference on Coordination Chemistry – ICCC (44° Edition)”, “Session Chair” within the Topic “T05 - Main Group Chemistry and Coordination Compounds“ (Organizing Committe)
ACHIEVEMENTS and HONOURS:
• 1999 – JSP Fellowship of the 34th Euchem Conference on Stereochemistry – Bürgenstock Conference (Bürgenstock, Lucerna, Switzerland)
• 1993-1995 and 1995-1997 – Nato Research Grant for the development of bilateral scientific collaborations between Italy and USA in collaboration with Prof. Saverio Florio (University of Bari, Italy) and Prof. Theodore Cohen (University of Pittsburgh, USA)
• 2009 – Recipient of the C.I.N.M.P.I.S. Prize “Innovation in Organic synthesis” awarded by the Interuniversities Consortium C.I.N.M.P.I.S.
• 2014 – Recipient of the Award of the Italian Chemical Society (Organic Division) for “Mechanistic and Theoretical Aspects of Organic Chemistry”
RESEARCH INTERESTS:
Current research interests revolve around:
• Functionalized Organolithiums and Lithium Carbenoids Chemistry: elucidation of the structure-reactivity relationship and of their dynamic behavior by means of a synergistic combination of ab initio calculations, X-ray analysis, and multinuclear magnetic resonance investigations; mechanistic and kinetics studies of enantiomerization of chiral organolithiums; synthesis of enantiomerically or diastereomerically enriched organolithiums and their stereospecific functionalization by interception with electrophiles; optimization of organometallic reactions by in-situ IR and NMR monitoring of the reactive intermediates involved; asymmetric synthesis of (new) heterocycles, natural product analogues, and “target molecules” of pharmaceutical and biological interest; the discovery of new reactions
• Organoboron and organofluorine chemistry
• Cross-coupling reactions
• Strained cycles in organic synthesis
• Preparation of key optically active “buiding blocks” as starting materials for asymmetric synthesis by means of biocatalytic processes employing enzymes or whole cells microorganisms (in collaboration with Dr. Paola Vitale)
• The development of new sustainable chemical processes using unconventional solvents (e.g., water and deep eutectic solvents)
• The development of new drugs for rare diseases
• Application of lithium chemistry in medicine and in the field of material sciences
MEMBERSHIPS:
• Italian Chemical Society (since 1992)
• The American Chemical Society (since1998)
• Interdivisional Group of "Organometallic Chemistry" of the Italian Chemical Society (since 1992)
• Interdivisional Group of "Green Chemistry" of the Italian Chemical Society (since 2014)
• Division of Chemical Education of the Italian Chemical Society (since 1992)
• International Society of Heterocyclic Chemistry (2003–2008; 2016)
MENTORING:
More than 50 undergraduates in “Pharmacy” and “Chemistry and Pharmaceutical Technology” (University of Bari, Italy); 1 Adjunct Assistant Professor (RTDa); 11 PhDs in “Chemical and Molecular Sciences”; 4 Postdocs/Fellows; 20 Erasmus students; 4 Visiting students.
PUBLICATIONS:
• Author/co-author of more than 115 papers in high-profile peer-reviewed international scientific journals (average IF 2010-2015: 5.4), including 8 Reviews; 6 editor-reviewed book chapters; 2 editor-reviewed specialized monographies; delivered more than 130 Communications (oral and poster) at national and international meetings (20 plenary and invited talks and seminars); H index: 28 (source: Scopus; 2040 citations)
• Co-Editor of "Lithium Compounds in Organic Synthesis From Fundamentals to Applications"; Publisher: Wiley-VCH Verlag GmbH & Co. KGaA, Boschst.12, 69469 Weinheim, Germany
• Co-author in the english-to-italian translation of two university textbooks of Organic Chemistry
OTHER INFORMATION:
• Application reviewer for MIUR-Italian Ministry of University and Research and peer-reviewer for many international scientific journals of Nature, American Chemical Society, Wiley-WCH, Thieme, The Royal Society of Chemistry, Bentham and Elsevier
• Collaboration with the pharmaceutical industry Dompè (L’Aquila, Italy) for the development of new drugs for rare diseases (Project PON PON01_00862; proponent: Consortium CINMPIS)
• PhD External Examiner: University of Florence (I), Department of Chemistry (Italy-France co-tutorship PhD programme, 2010), University of Camerino (I), Department of Chemistry (2014), University of Oslo, Department of Chemistry (Norway) (2016), University of Calabria (I), Department of Chemistry and Chemical Technologies (2016), University of Alicante, Department of Organic Chemistry (Spain) (2017).
• Board of Directors’ member of the Doctorate School in “Chemical and Molecular Sciences”
• Departmental coordinator of three Erasmus programme between the Department of Pharmacy–Drug Sciences and (i) the Ludwig-Maximilians-Universität München (Germany), (ii) the Oslo University (Oslo, Norway), (III) the University of Rouen (Rouen, France)
• Founding and board of directors’ member of the academic spin-off "SYNCHIMIA Materials & Nanomaterials" (LINK) at the University of Bari for the preparation of (a) innovative material and nanomaterial useful for fotonics and electronics, (b) chiral nonracemic products of pharmaceutical, biological and agrochemical interest, (c) heterocyclic compounds, (d) pheromones traps
• Legally authorized representative on behalf of the University of Bari within the Consortium C.I.N.M.P.I.S (since 2012)
• Director of Consortium C.I.N.M.P.I.S (since 2016)
• Responsible for the management of the CINMPIS project “Synthesis of New Molecules as Drugs for Rare Diseases” funded by MIUR (code: COCM8470P0) (2017)
• Volunteer Translator for EURORDIS (The European Organization for Rare Desease) whose purpose is to empower rare disease organizations, patients and families throughout Europe so as to contribute in building a rare disease community across national and linguistic lines
• Hobbies: trekking, golf, shooting, collecting stamps, and playing chess
